Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J‐Aggregates with Bright Near‐Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications
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Colloidal nanoparticles (NPs) containing near‐infrared‐fluorescent J‐aggregates (JAGGs) of pyrrolopyrrole cyanines (PPcys) stabilized by amphiphilic block co‐polymers were prepared in aqueous medium. JAGG formation can be tuned by means of the chemical structure of PPcys, the concentration of chromophores inside the polymeric NPs, and ultrasonication. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, which is ideal for long‐term bioimaging.
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Currently reported J-aggregates formed in an aqueous environment, in particular polymethine-based J-aggregates, generally showed relatively low Φfl.
“It is important to stress that the currently reported J-aggregates formed in an aqueous environment, in particular, polymethine-based J-aggregates, generally showed relatively low Φfl.121−124”
From The Pursuit of Shortwave Infrared-Emitting Nanoparticles with Bright Fluorescence through Molecular Design and Excited-State Engineering of Molecular Aggregates (2022) · cites this paper as [122]
The Introduction (page unavailable) says that existing dye J-aggregates have relatively low fluorescence quantum yields and gives an example of J-aggregates formed in water. It does not specifically establish that polymethine-based J-aggregates in aqueous environments generally have low quantum yields. (LLM, conf=0.82)
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Cites
Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole
Luo, J., Xie, Z., Lam, J. W. Y., Cheng, L., Tang, B. Z., Chen, H., Qiu, C., Kwok, H. S., Zhan, X., Liu, Y., et al. (2001) · Chemical Communications · doi:10.1039/b105159h · Cited by 8,358 · see citing works
In vivo near-infrared fluorescence imaging
Frangioni, J. V. (2003) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2003.08.007 · Cited by 2,655 · see citing works
J‐Aggregates: From Serendipitous Discovery to Supramolecular Engineering of Functional Dye Materials
Würthner, F., Kaiser, T. E., & Saha‐Möller, C. R. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201002307 · Cited by 2,597 · see citing works
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Cabral, H., Matsumoto, Y., Mizuno, K., Chen, Q., Murakami, M., Kimura, M., Terada, Y., Kano, M. R., Miyazono, K., Uesaka, M., et al. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.166 · Cited by 2,429 · see citing works
Image-guided cancer surgery using near-infrared fluorescence
Vahrmeijer, A. L., Hutteman, M., van der Vorst, J. R., van de Velde, C. J. �., & Frangioni, J. V. (2013) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2013.123 · Cited by 1,470 · see citing works
Spectral Absorption and Fluorescence of Dyes in the Molecular State
Jelley, E. E. (1936) · Nature · doi:10.1038/1381009a0 · Cited by 1,419 · see citing works
Lovell, J. F., Jin, C. S., Huynh, E., Jin, H., Kim, C., Rubinstein, J. L., Chan, W. C. W., Cao, W., Wang, L. V., & Zheng, G. (2011) · Nature Materials · doi:10.1038/nmat2986 · Cited by 1,364 · see citing works
Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects
Maeda, H. (2010) · Bioconjugate Chemistry · doi:10.1021/bc100070g · Cited by 997 · see citing works
The role of micelle size in tumor accumulation, penetration, and treatment
Wang, J., Mao, W., Lock, L. L., Tang, J., Sui, M., Sun, W., Cui, H., Xu, D., & Shen, Y. (2015) · ACS Nano · doi:10.1021/acsnano.5b02017 · Cited by 635 · see citing works
Lineshapes of molecular aggregates, exchange narrowing and intersite correlation
Knapp, E. (1984) · Chemical Physics · doi:10.1016/s0301-0104(84)85174-5 · Cited by 596 · see citing works
The Dimeric State of Cyanine Dyes
West, W., & Pearce, S. (1965) · The Journal of Physical Chemistry · doi:10.1021/j100890a019 · Cited by 534 · see citing works
Über die Veränderlichkeit der Absorptionsspektren in Lösungen und die Nebenvalenzen als ihre Ursache
Scheibe, G. (1937) · Angewandte Chemie · doi:10.1002/ange.19370501103 · Cited by 502 · see citing works
Supramolecular Construction of Fluorescent J‐Aggregates Based on Hydrogen‐Bonded Perylene Dyes
Kaiser, T. E., Wang, H., Stepanenko, V., & Würthner, F. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200701139 · Cited by 500 · see citing works
Altınoğlu, E. İ., Russin, T. J., Kaiser, J. M., Barth, B. M., Eklund, P. C., KESTER, M. A., & Adair, J. H. (2008) · ACS Nano · doi:10.1021/nn800448r · Cited by 430 · see citing works
Molecular, Nematic and Crystal States of I: I-Diethyl--Cyanine Chloride
Jelley, E. E. (1937) · Nature · doi:10.1038/139631b0 · Cited by 420 · see citing works
Aggregation of sensitizing dyes in solution and their adsorption onto silver halides
Herz, A. H. (1977) · Advances in Colloid and Interface Science · doi:10.1016/0001-8686(77)80011-0 · Cited by 360 · see citing works
Möbius, D. (1995) · Advanced Materials · doi:10.1002/adma.19950070503 · Cited by 342 · see citing works
Fluorescence-enhanced, near infrared diagnostic imaging with contrast agents
Sevick-Muraca, E. M., Houston, J. P., & Gurfinkel, M. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00356-3 · Cited by 329 · see citing works
Würthner, F., Kaiser, T. E., & Saha‐Möller, C. R. (2011) · Angewandte Chemie · doi:10.1002/ange.201002307 · Cited by 299 · see citing works
Würthner, F. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00042 · Cited by 276 · see citing works
Sengupta, S., & Würthner, F. (2013) · Accounts of Chemical Research · doi:10.1021/ar400017u · Cited by 243 · see citing works
Eisele, D. M., Cone, C. W., Bloemsma, E. A., Vlaming, S. M., van der Kwaak, C., Silbey, R., Bawendi, M. G., Knoester, J., Rabe, J. P., & Bout, D. A. V. (2012) · Nature Chemistry · doi:10.1038/nchem.1380 · Cited by 205 · see citing works
Soper, S. A., & Mattingly, Q. L. (1994) · Journal of the American Chemical Society · doi:10.1021/ja00088a010 · Cited by 197 · see citing works
Li, X., Zhang, X., Ghosh, S., & Würthner, F. (2008) · Chemistry - A European Journal · doi:10.1002/chem.200800915 · Cited by 178 · see citing works
Near‐Infrared Dyes and Fluorophores Based on Diketopyrrolopyrroles
Fischer, G., Ehlers, A. P., Zumbusch, A., & Daltrozzo, E. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200604763 · Cited by 176 · see citing works
Würthner, F., Yao, S., & Beginn, U. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200351414 · Cited by 163 · see citing works
Photophysics of Cy3-Encapsulated Calcium Phosphate Nanoparticles
Muddana, H. S., Morgan, T. T., Adair, J. H., & Butler, P. J. (2009) · Nano Letters · doi:10.1021/nl803658w · Cited by 155 · see citing works
Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles
Pittet, M. J., Świrski, F. K., REYNOLDS, F. H., Josephson, L., & Weissleder, R. (2006) · Nature Protocols · doi:10.1038/nprot.2006.11 · Cited by 155 · see citing works
Selective NIR chromophores: Bis(Pyrrolopyrrole) Cyanines
Fischer, G., Daltrozzo, E., & Zumbusch, A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201004829 · Cited by 146 · see citing works
Supramolecular Construction of Fluorescent J‐Aggregates Based on Hydrogen‐Bonded Perylene Dyes
Kaiser, T. E., Wang, H., Stepanenko, V., & Würthner, F. (2007) · Angewandte Chemie · doi:10.1002/ange.200701139 · Cited by 146 · see citing works
Shao, C., Grüne, M., Stolte, M., & Würthner, F. (2012) · Chemistry - A European Journal · doi:10.1002/chem.201201661 · Cited by 145 · see citing works
Pyrrolopyrrole Cyanine Dyes: A New Class of Near‐Infrared Dyes and Fluorophores
Fischer, G. M., Isomäki‐Krondahl, M., Göttker‐Schnetmann, I., Daltrozzo, E., & Zumbusch, A. (2009) · Chemistry – A European Journal · doi:10.1002/chem.200801996 · Cited by 144 · see citing works
Reversible Self‐Organization of Semisynthetic Zinc Chlorins into Well‐Defined Rod Antennae
Huber, V., Katterle, M., Lysetska, M., & Würthner, F. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200462762 · Cited by 122 · see citing works
Stimuli-Responsive Photoacoustic Nanoswitch for in Vivo Sensing Applications
Ng, K. K., Shakiba, M., Huynh, E., Weersink, R., Roxin, Á., Wilson, B. C., & Zheng, G. (2014) · ACS Nano · doi:10.1021/nn502858b · Cited by 119 · see citing works
Multiplet structure of aggregated states in 1,1′-diethyl-2,2′-cyanine dye
Cooper, W. J. (1970) · Chemical Physics Letters · doi:10.1016/0009-2614(70)80252-4 · Cited by 97 · see citing works
J-aggregation and disaggregation of indocyanine green in water
Rotermund, F., Weigand, R., & Penzkofer, А. (1997) · Chemical Physics · doi:10.1016/s0301-0104(97)00151-1 · Cited by 94 · see citing works
Asymmetric PPCys: Strongly fluorescing NIR labels
Fischer, G., Jüngst, C., Isomäki‐Krondahl, M., Gauss, D., Möller, H. M., Daltrozzo, E., & Zumbusch, A. (2010) · Chemical Communications · doi:10.1039/c0cc00359j · Cited by 90 · see citing works
Shakiba, M., Ng, K. K., Huynh, E., Chan, H. H. L., Charron, D. M., Chen, J., Muhanna, N., Foster, F. S., Wilson, B. C., & Zheng, G. (2015) · Nanoscale · doi:10.1039/c5nr08165c · Cited by 90 · see citing works
Huang, S., Upputuri, P. K., Liu, H., Pramanik, M., & Wang, M. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02367j · Cited by 70 · see citing works
Self-citationHuang, S., Liu, S., Wang, K., Yang, C., Luo, Y., Zhang, Y., Cao, B., Kang, Y., & Wang, M. (2014) · Nanoscale · doi:10.1039/c4nr05576d · Cited by 60 · see citing works
Self-citationSelf-Sensing Porphysomes for Fluorescence-Guided Photothermal Therapy
Ng, K. K., Takada, M., Jin, C. C. S., & Zheng, G. (2015) · Bioconjugate Chemistry · doi:10.1021/bc500595d · Cited by 59 · see citing works
Crystallization-induced red emission of a facilely synthesized biodegradable indigo derivative
Yang, C., Trịnh, Q. T., Wang, X., Tang, Y., Wang, K., Huang, S., Chen, X., Mushrif, S. H., & Wang, M. (2015) · Chemical Communications · doi:10.1039/c4cc09540e · Cited by 57 · see citing works
Self-citationYang, C., Liu, H., Zhang, Y., Xu, Z., Wang, X., Cao, B., & Wang, M. (2016) · Biomacromolecules · doi:10.1021/acs.biomac.6b00092 · Cited by 52 · see citing works
Self-citationHuang, S., Kannadorai, R. K., Chen, Y., Liu, Q., & Wang, M. (2015) · Chemical Communications · doi:10.1039/c4cc09399b · Cited by 51 · see citing works
Self-citationWürthner, F., Yao, S., & Beginn, U. (2003) · Angewandte Chemie · doi:10.1002/ange.200351414 · Cited by 48 · see citing works
Water-soluble pyrrolopyrrole cyanine (PPCy) NIR fluorophores
Wiktorowski, S., Rosazza, C., Winterhalder, M., Daltrozzo, E., & Zumbusch, A. (2014) · Chemical Communications · doi:10.1039/c4cc01014k · Cited by 45 · see citing works
NIR‐Farbstoffe und NIR‐Fluorophore aus Diketopyrrolopyrrolen
Fischer, G., Ehlers, A. P., Zumbusch, A., & Daltrozzo, E. (2007) · Angewandte Chemie · doi:10.1002/ange.200604763 · Cited by 41 · see citing works
Selektive Nah‐Infrarot‐Chromophore: Bis(pyrrolopyrrol)‐Cyanine
Fischer, G., Daltrozzo, E., & Zumbusch, A. (2011) · Angewandte Chemie · doi:10.1002/ange.201004829 · Cited by 34 · see citing works
Huang, S., Wang, K., Wang, S., Wang, Y., & Wang, M. (2016) · Advanced Materials Interfaces · doi:10.1002/admi.201600259 · Cited by 28 · see citing works
Self-citationWang, K., Luo, Y., Huang, S., Yang, H., Liu, B., & Wang, M. (2015) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.27531 · Cited by 27 · see citing works
Self-citationA Preliminary Study of the In Vivo Behaviour of an Emulsion Formulation of Indocyanine Green
Devoisselle, J., Bégu, S., Mordon, S. R., Desmettre, T. J., & Maillols, H. (1998) · Lasers in Medical Science · doi:10.1007/s101030050008 · Cited by 26 · see citing works
Reversible Selbstorganisation semisynthetischer Zinkchlorine zu definierten Stabantennen
Huber, V., Katterle, M., Lysetska, M., & Würthner, F. (2005) · Angewandte Chemie · doi:10.1002/ange.200462762 · Cited by 26 · see citing works
Flagged first, then by citations
Research works printed but not linked: 45
- E. M. Sevick-Muraca, J. P. Houston, M. Gurfinkel, Curr. Opin. Chem. Biol. 2002, 6, 642-650;
- J. V. Frangioni, Curr. Opin. Chem. Biol. 2003, 7, 626-634.
- A. L. Vahrmeijer, M. Hutteman, J. R. van der Vorst, C. J. van de Velde, J. V. Frangioni, Nat. Rev. Clin. Oncol. 2013, 10, 507-518.
- H. Maeda, Bioconjugate Chem. 2010, 21, 797-802.
- M. J. Pittet, F. K. Swirski, F. Reynolds, L. Josephson, R. Weissleder, Nat. Protoc. 2006, 1, 73;
- S. Huang, S. Liu, K. Wang, C. Yang, Y. Luo, Y. Zhang, B. Cao, Y. Kang, M. Wang, Nanoscale 2015, 7, 889-895.
- H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M. R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, K. Kataoka, Nat. Nanotech. 2011, 6, 815-823;
- J. Wang, W. Mao, L. L. Lock, J. Tang, M. Sui, W. Sun, H. Cui, D. Xu, Y. Shen, ACS Nano 2015, 9, 7195-7206.
- K. Wang, Y. Luo, S. Huang, H. Yang, B. Liu, M. Wang, J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 1032-1042;
- C. Yang, H. Liu, Y. Zhang, Z. Xu, X. Wang, B. Cao, M. Wang, Biomacromolecules 2016, 17, 1673-1683.
- E. E. Jelley, Nature 1936, 138, 1009-1010;
- G. Scheibe, Angew. Chem 1936, 49, 563; (
- E. E. Jelley, Nature 1937, 139, 631-632; (
- G. Scheibe, Angew. Chem. Int. Ed. Eng. 1937, 50, 212-219.
- A. Herz, Adv. Colloid Interface Sci. 1977, 8, 237-298;
- D. Möbius, Adv. Mater. 1995, 7, 437-444;
- F. Würthner, T. E. Kaiser, C. R. Saha- Möller, Angew. Chem. Int. Ed. Eng. 2011, 50, 3376-3410;
- S. Sengupta, F. Würthner, Acc. Chem. Res. 2013, 46, 2498-2512.
- F. Rotermund, R. Weigand, A. Penzkofer, Chem. Phys. 1997, 220, 385- 392.
- J. F. Lovell, C. S. Jin, E. Huynh, H. Jin, C. Kim, J. L. Rubinstein, W. C. Chan, W. Cao, L. V. Wang, G. Zheng, Nat. Mater. 2011, 10, 324-332;
- M. Shakiba, K. K. Ng, E. Huynh, H. Chan, D. M. Charron, J. Chen, N. Muhanna, F. S. Foster, B. C. Wilson, G. Zheng, Nanoscale 2016, 8, 12618-12625;
- K. K. Ng, M. Takada, C. C. Jin, G. Zheng, Bioconjugate Chem. 2015, 26, 345-351.
- T. E. Kaiser, H. Wang, V. Stepanenko, F. Würthner, Angew. Chem. Int. Ed. Eng. 2007, 46, 5541-5544.
- G. M. Fischer, A. P. Ehlers, A. Zumbusch, E. Daltrozzo, Angew. Chem. Int. Ed. Eng. 2007, 46, 3750-3753;
- G. M. Fischer, M. Isomäki- Krondahl, I. Göttker-Schnetmann, E. Daltrozzo, A. Zumbusch, Chem. Eur. J. 2009, 15, 4857-4864;
- S. Wiktorowski, C. Rosazza, M. J. Winterhalder, E. Daltrozzo, A. Zumbusch, Chem. Commun. 2014, 50, 4755-4758;
- G. M. Fischer, E. Daltrozzo, A. Zumbusch, Angew. Chem. Int. Ed. Eng. 2011, 50, 1406-1409;
- G. M. Fischer, C. Jüngst, M. Isomäki-Krondahl, D. Gauss, H. M. Möller, E. Daltrozzo, A. Zumbusch, Chem. Commun. 2010, 46, 5289-5291.
- K. K. Ng, M. Shakiba, E. Huynh, R. A. Weersink, A. Roxin, B. C. Wilson, G. Zheng, ACS Nano 2014, 8, 8363-8373.
- W. West, S. Pearce, J. Phy. Chem. 1965, 69, 1894-1903;
- F. Würthner, Y. Sheng, B. Uwe, Angew. Chem. Int. Ed. Eng. 2003, 42, 3247- 3250;
- C. Shao, M. Grüne, M. Stolte, F. Würthner, Chem. Eur. J. 2012, 18, 13665-13677; (
- F. Würthner, Acc. Chem. Res. 2016, 49, 868-876.
- E. Knapp, Chem. Phys. 1984, 85, 73-82.
- S. A. Soper, Q. L. Mattingly, J. Am. Chem. Soc. 1994, 116, 3744-3752.
- H. S. Muddana, T. T. Morgan, J. H. Adair, P. J. Butler, Nano Lett. 2009, 9, 1559-1566;
- E. I. Altınoğlu, T. J. Russin, J. M. Kaiser, B. M. Barth, P. C. Eklund, M. Kester, J. H. Adair, ACS Nano 2008, 2, 2075- 2084.
- J. Devoisselle, S. Soulie-Begu, S. Mordon, T. Desmettre, H. Maillols, Laser. Med. Sci. 1998, 13, 279-282.
- W. Cooper, Chem. Phys. Lett. 1970, 7, 73-77;
- D. Eisele, C. Cone, E. Bloemsma, S. Vlaming, C. van der Kwaak, R. J. Silbey, M. G. Bawendi, J. Knoester, J. Rabe, D. V. Bout, Nat. Chem. 2012, 4, 655-662.
- X. Q. Li, X. Zhang, S. Ghosh, F. Würthner, Chem. Eur. J. 2008, 14, 8074-8078;
- V. Huber, M. Katterle, M. Lysetska, F. Würthner, Angew. Chem. Int. Ed. Eng. 2005, 117, 3208-3212.
- C. Yang, Q. T. Trinh, X. Wang, Y. Tang, K. Wang, S. Huang, X. Chen, S. H. Mushrif, M. Wang, Chem. Commun. 2015, 51, 3375-3378.
- S. Huang, P. K. Upputuri, H. Liu, M. Pramanik, M. Wang, J. Mater. Chem. B 2016, 4, 1696-1703;
- S. Huang, R. K. Kannadorai, Y. Chen, Q. Liu, M. Wang, Chem. Commun. 2015, 51, 4223-4226.
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Sun, P., Wu, Q., Sun, X., Miao, H., Deng, W., Zhang, W., Fan, Q., & Huang, W. (2018) · Chemical Communications · doi:10.1039/c8cc08096h · Cited by 167 · see citing works
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Xu, S., Liu, H., Huan, S., Yuan, L., & Zhang, X. (2020) · Materials Chemistry Frontiers · doi:10.1039/d0qm00557f · Cited by 133 · see citing works
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Sun, C., Zhao, M., Zhu, X., Pei, P., & Zhang, F. (2021) · CCS Chemistry · doi:10.31635/ccschem.021.202101332 · Cited by 64 · see citing works
Plasmon-Enhanced Oxidase-Like Activity and Cellular Effect of Pd-Coated Gold Nanorods
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Aggregation-induced emission luminogens for image-guided surgery in non-human primates
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Tian, Y., Yin, D., & Yan, L. (2022) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1831 · Cited by 54 · see citing works
Orderly Self‐Assembly of Organic Fluorophores for Sensing and Imaging
Li, Z., Liang, P., Ren, T., Yuan, L., & Zhang, X. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202305742 · Cited by 54 · see citing works
Wang, L., Xiong, Z., Ran, X., Tang, H., & Cao, D. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.110040 · Cited by 50 · see citing works
Piwoński, H., Nozue, S., Fujita, H., Michinobu, T., & Habuchi, S. (2021) · Nano Letters · doi:10.1021/acs.nanolett.0c04928 · Cited by 45 · see citing works
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Brodeur, J., Lei, H., Malinge, A., Eizner, E., Skene, W. G., & Kéna‐Cohen, S. (2019) · Advanced Optical Materials · doi:10.1002/adom.201901144 · Cited by 44 · see citing works
Upputuri, P. K., Yang, C., Huang, S., Wang, K., Wang, M., & Pramanik, M. (2018) · Journal of Biomedical Optics · doi:10.1117/1.jbo.24.3.031002 · Cited by 39 · see citing works
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Piwoński, H., Nozue, S., & Habuchi, S. (2022) · ACS Nanoscience Au · doi:10.1021/acsnanoscienceau.1c00038 · Cited by 39 · see citing works
Organic fluorescent nanoparticles with NIR-II emission for bioimaging and therapy
Dang, H., & Yan, L. (2020) · Biomedical Materials · doi:10.1088/1748-605x/abca4a · Cited by 34 · see citing works
Transparent and Colorless Dye‐Sensitized Solar Cells Based on Pyrrolopyrrole Cyanine Sensitizers
Baron, T., Naim, W., Nikolinakos, I., Andrin, B., Pellegrin, Y., Jacquemin, D., Haacke, S., Sauvage, F., & Odobel, F. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202207459 · Cited by 35 · see citing works
Li, S., Yan, X., Zhang, J., Guo, X., Zhang, Y., Su, M., Yang, C. F., Zhang, H., & Li, C. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202105189 · Cited by 29 · see citing works
Self-citationPotopnyk, M. A., Volyniuk, D. Y., Ceborska, M., Cmoch, P., Hladka, I., Danyliv, Y., & Gražulevičius, J. V. (2018) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.8b02098 · Cited by 29 · see citing works
Zhou, X., Lin, S., & Yan, H. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01449-y · Cited by 29 · see citing works
Supramolecular ensembles modified by near-infrared dyes and their biological applications
Jin, T., Huang, C., Cui, M., Yang, Y., Wang, Z., Zhu, W. P., & Qian, X. H. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01829e · Cited by 25 · see citing works
Pyrrolopyrrole aza boron dipyrromethene based two-photon fluorescent probes for subcellular imaging
Zhou, Y., Ma, C., Gao, N., Wang, Q., Lo, P., Wong, K. S., Xu, Q., Kinoshita, T., & Ng, D. K. P. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb01832d · Cited by 24 · see citing works
Yang, C., Wang, X., Huang, S., & Wang, M. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201705226 · Cited by 23 · see citing works
Self-citationXu, Y., Meng, X. J., Zhao, Y., Jia, M., Zhu, H., Song, J., Su, Y., Qiao, W., Qi, J., & Wang, Z. Y. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c06225 · Cited by 22 · see citing works
Tuning of Molecular Aggregation and Photoresponse of Narrow-band Organic Photodetectors
Xu, Y., Zhao, Y., Zhang, J., Wang, X., Gao, S., Wang, Z., Qiao, W., & Wang, Z. Y. (2023) · ACS Applied Electronic Materials · doi:10.1021/acsaelm.3c00118 · Cited by 21 · see citing works
Self-citationHuang, S., Liu, W., Huang, J., Wang, X., Yang, C., Bohra, H., Liu, Q., & Wang, M. (2018) · ACS Applied Bio Materials · doi:10.1021/acsabm.8b00321 · Cited by 20 · see citing works
Self-citationYang, C., Zhang, W., Pang, X., Xiao, F., Kalva, S. K., Zhang, Y., Pramanik, M., Tian, L., Liu, G., & Wang, M. (2022) · Aggregate · doi:10.1002/agt2.261 · Cited by 20 · see citing works
Self-citationApplications of cyanine-nanoparticle systems in science: Health and environmental perspectives
Marcelo, G. A., Galhano, J., & Oliveira, E. (2022) · Dyes and Pigments · doi:10.1016/j.dyepig.2022.110756 · Cited by 20 · see citing works
Zhu, J., Tang, B. Z., & Lo, K. K. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201901029 · Cited by 18 · see citing works
Huang, S., Yang, C., Huang, J., Wang, X., & Wang, M. (2018) · Dyes and Pigments · doi:10.1016/j.dyepig.2018.02.029 · Cited by 18 · see citing works
Self-citationWang, L., Xin, S., Xie, F., Ran, X., Tang, H., & Cao, D. (2022) · Journal of Materials Chemistry C · doi:10.1039/d2tc02426h · Cited by 17 · see citing works
Luminescence Probes in Bio-Applications: From Principle to Practice
Yan, T., Weng, F., Ming, Y., Zhu, S., Zhu, M., Wang, C., Guo, C., & Zhu, K. (2024) · Biosensors · doi:10.3390/bios14070333 · Cited by 14 · see citing works
The luminous frontier: transformative NIR-IIa fluorescent polymer dots for deep-tissue imaging
Lawrance, R., Chowdhury, P., Lin, H.-C., & Chan, Y. (2024) · RSC Applied Polymers · doi:10.1039/d4lp00076e · Cited by 13 · see citing works
Prasad, R., Prerna, K., Temgire, M., Banerjee, P., Kumari, R., Kundu, G. C., Hattila, D., Mangannavar, C. V., Meena, A. S., Gorain, M., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401233 · Cited by 13 · see citing works
Zhang, C., An, J., Wu, J., Liu, W., Rha, H., Kim, J. S., & Wang, P. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114701 · Cited by 11 · see citing works
Emerging Trends of J‐Aggregate Formation within Polymeric Nanoassemblies
Hou, M., & Liu, S. (2022) · Macromolecular Chemistry and Physics · doi:10.1002/macp.202200414 · Cited by 9 · see citing works
Bioinspired Fluorescent Polymers: Synthesis, Processing, and Applications†
Xu, H., Zhang, W., & Wang, M. (2022) · Chinese Journal of Chemistry · doi:10.1002/cjoc.202200493 · Cited by 9 · see citing works
Self-citationTransparent and Colorless Dye‐Sensitized Solar Cells Based on Pyrrolopyrrole Cyanine Sensitizers
Baron, T., Naim, W., Nikolinakos, I., Andrin, B., Pellegrin, Y., Jacquemin, D., Haacke, S., Sauvage, F., & Odobel, F. (2022) · Angewandte Chemie · doi:10.1002/ange.202207459 · Cited by 8 · see citing works
Polymerizations of Diketopyrrolopyrrole-Type Dyes in Unconventional Orientation
Zhang, R., Sun, M., Wang, X., Yan, H., Zhang, G., & Zhang, Q. (2020) · ACS Applied Polymer Materials · doi:10.1021/acsapm.0c00995 · Cited by 8 · see citing works
Self-citationOrderly Self‐Assembly of Organic Fluorophores for Sensing and Imaging
Li, Z., Liang, P., Ren, T., Yuan, L., & Zhang, X. (2023) · Angewandte Chemie · doi:10.1002/ange.202305742 · Cited by 7 · see citing works
Wang, M., Zhang, Y., & Zhang, W. (2022) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.1c03865 · Cited by 7 · see citing works
Self-citationBODIPY Dyes and Their Analogues
Kubota, Y. (2021) · Springer eBooks · doi:10.1007/978-981-33-4392-4_5 · Cited by 7 · see citing works
Wang, K., Bohra, H., Gonçalves, R. A., Bhatnagar, H., Wu, Y., Wang, X., Wang, Z., Wei, X., Lam, Y. M., & Wang, M. (2019) · Langmuir · doi:10.1021/acs.langmuir.9b00334 · Cited by 7 · see citing works
Self-citationYang, Y., Li, J., Li, H., Jiang, Z., Zhou, Z., Wang, Z. M., Wang, B., Gao, Y., & Lan, X. (2025) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.5c01089 · Cited by 6 · see citing works
Ultrabright Silica-Coated Organic Nanocrystals for Two-Photon In Vivo Imaging
Shenoi-Perdoor, S., Dubois, F., Barbara, A., Nguyen, C., Ali, L. M. A., Gary‐Bobo, M., Hristovska, I., Combet, K., Pascual, O., Micouin, G., et al. (2020) · ACS Applied Nano Materials · doi:10.1021/acsanm.0c02499 · Cited by 6 · see citing works
Lu, L., Chen, N., Yuan, B., Wang, J., He, L., Wu, A., & Li, J. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102210 · Cited by 6 · see citing works
Rational design and synthesis of pyrrolo-pyridine dinitrile dyes with strong dual-state emission
Xu, Y., Zhu, H., Zhao, Y., Li, Y., Shi, W., Zhu, Y., Wang, C., Chen, D., Qiao, W., & Wang, Z. Y. (2024) · Dyes and Pigments · doi:10.1016/j.dyepig.2024.112505 · Cited by 4 · see citing works
Zhang, Y., Lou, H., & Wang, M. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202303204 · Cited by 4 · see citing works
Self-citationShi, W., Xu, Y., Zhu, H., Qiao, W., & Wang, Z. Y. (2025) · Dyes and Pigments · doi:10.1016/j.dyepig.2025.112847 · Cited by 1 · see citing works
NIR Emissive Biomimetic Ghost Nanovesicles for Site-Selective Solid Tumor ImagingPreprint
PRASAD, R., Prerna, K., Temgire, M., Banerjee, P., Kumari, R., Kundu, G. C., Kumari, S., Bellare, J., Dubey, V. K., Chandra, P., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4616433/v1
- Authors
- Yang, C., Wang, X., Wang, M., Xu, K., & Xu, C.
- Affiliations
- Nanyang Technological University (SG)
- Corresponding author
- Wang, Mingfeng
- Venue
- Chemistry – A European Journal
- Publisher
- Wiley
- Published
- 2017-01-20
- Volume
- 23
- Issue
- 18
- Pages
- 4310-4319
- ISSN
- 0947-6539 (ISSN-L)
- 1521-3765
- OpenAlex
- W2560091949
- Cited by
- 54
- References
- 52
- Citations by year
- 2025: 2 · 2024: 7 · 2023: 4 · 2022: 13 · 2021: 6 · 2020: 8 · 2019: 5 · 2018: 7 · 2017: 2
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Chemistry - A European Journal (publishedVersion)
- PubMed (publishedVersion)
- DR-NTU (Nanyang Technological University) (submittedVersion)
- Funders
- Nanyang Assistant Professorship (M4080992.120)
- AcRF Tier 2 (ARC 36/13)
- NTU-Northwestern Institute for Nanomedicine (M4081502.F40)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Photochemistry and Electron Transfer Studies
- Physical Sciences › Materials Science › Materials Chemistry › Porphyrin and Phthalocyanine Chemistry
- Keywords
- J-aggregates, colloidal nanoparticles, near-infrared fluorescence, amphiphilic block copolymers, aqueous nanoparticle synthesis, spectral tuning, photostability, bioimaging, indocyanine green
- MeSH terms
- Animals, Cell Survival, Colloids, Fluorescent Dyes, Humans, Mice, Nude, Neoplasms, Polymers, Pyrroles, Sonication, Spectrophotometry, Transplantation, Heterologous, Water, Spectroscopy, Near-Infrared, Cell Line, Tumor, Mice, Nanoparticles
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