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Wound Healing--Aiming for Perfect Skin Regeneration

Martin, Paul·1997·Science

Abstract

The healing of an adult skin wound is a complex process requiring the collaborative efforts of many different tissues and cell lineages. The behavior of each of the contributing cell types during the phases of proliferation, migration, matrix synthesis, and contraction, as well as the growth factor and matrix signals present at a wound site, are now roughly understood. Details of how these signals control wound cell activities are beginning to emerge, and studies of healing in embryos have begun to show how the normal adult repair process might be readjusted to make it less like patching up and more like regeneration.

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Metadata

Authors
Martin, P.
Venue
Science
Published
1997-04-04
Volume
276
Issue
5309
Pages
75-81
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1989021197
Cited by
4,804
References
2
FWCI
103.77
Type
journal article
Language
en
Open access
closed

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