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Catecholamine innervation of the human cerebral cortex as revealed by comparative immunohistochemistry of tyrosine hydroxylase and dopamine-beta-hydroxylase
Abstract
The organization of the cortical monoamine systems, dopamine (DA), and noradrenaline (NA), which have been studied extensively in the rat and more recently in the monkey, had not yet been investigated directly in the human brain. We report here the first systematic account of the regional and laminar distributions of the catecholamine fibers in the human cerebral cortex, using immunohistochemistry of the catecholamine biosynthetic enzymes, tyrosine hydroxylase (TH), and dopamine‐β‐hydroxylase (DBH) in 13 cytoarchitectonic areas (4, 6, 9, 3b, 5, 40, 17, 18, 23, 24, 29, insula, and hippocampus) sampled postmortem. The noradrenergic (NA) innervation, mapped with DBH‐immunoreactivity (DBH‐IR), displayed a characteristic density gradient in the neocortex (highest in the primary sensorimotor areas, decreasing rostrally and caudally) that contrasted with the more uniform density in the limbic cortices (24, 23, 29, insula, hippocampus). NA axons were present in all cortical layers and were least numerous in layer I. The DBH‐IR fibers were only partly TH‐immunostained (10–50%, on double‐labeled sections), suggesting a heterogeneity of the cortical NA axons. The putative dopaminergic (DA) fibers were identified by comparing alternate or double‐immunolabeled (DBH‐TH) sections, as the TH‐IR fibers which contain no DBH‐IR. A DA‐like innervation was present in all cortical areas, with major regional differences in density and laminar distribution, which closely paralleled cytoarchitectural buildups: (1) the DA‐like innervation was densest in the agranular areas, primary and secondary motor areas, anterior cingulate, and insula; it distributed throughout layers I–VI; (2) density was lower in the granular cortices, areas 9 (prefrontal cortex), 23, 3b, 5, 40, and 18, displaying a bilaminar pattern in layers I and V–VI. In all areas, DA‐like fibers were most abundant in the molecular layer, with a predominant distribution in its deepest part. Convoluted and coily fibers represented a unique morphologic aspect of the CA innervation in the human cortex. These findings are in agreement with findings in nonhuman primates and demonstrate major evolutionary changes in the organization of the cortical aminergic input as compared with rodents. The most striking features are the expansion of the DA innervation to the whole cortex and the peak of highest density in the motor areas. The regional differentiation of NA innervation is also accentuated. Slight differences were found in the laminar distributions of the amines in humans and primates. These data seem quite promising and open new research fields in neurologic and psychiatric diseases.
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In the citing paper
“Notably, many if not all regions of the interoceptive circuit in Figure 7, are characterized by a high density of dopaminergic receptors and terminals across all cortical layers; this is particularly well-established for visceromotor regions like AIC, ACC, or OFC (Gaspar et al., 1989; Hurd et al., 2001; Lewis et al., 2001).”
From Allostatic Self-efficacy: A Metacognitive Theory of Dyshomeostasis-Induced Fatigue and Depression (2016) · cites this paper as Gaspar et al., 1989
In the citing paper
“It is well established that the aIns receives dopaminergic innervations (Gaspar et al., 1989) and processes dopamine-associated RPEs.”
From Cognitive flexibility in adolescence: Neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development (2015) · cites this paper as Gaspar et al., 1989
In the citing paper
“The entire granular subregion has notably high dopamine utilization (Gaspar et al., 1989) with the aIC having high density D1-subtype receptors surrounding dopaminergic terminals from the VTA and substantia nigra.”
From The Insula: A Brain Stimulation Target for the Treatment of Addiction (2019) · cites this paper as Gaspar et al., 1989
In the citing paper
“Furthermore, the insula has a high level of endogenous opioids (Gaspar et al., 1989), high density of µ-subtype opioid receptors (Baumgartner et al., 2006), high density of hypocretin subtype-1 receptors (Hollander et al., 2008), and a high level of nicotinic acetylcholine receptors (nAChRs) containing the β2 subunit”
From The Insula: A Brain Stimulation Target for the Treatment of Addiction (2019) · cites this paper as Gaspar et al., 1989
Citations
Cites
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
Handbook of chemical neuroanatomy
(2005) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(05)80001-6 · Cited by 906
Everitt, B. J., Hökfelt, T. G. M., Terenius, L. Y., Tatemoto, K., Mutt, V., & Goldstein, M. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90036-8 · Cited by 871
Scatton, B., Javoy-Agid, F., Rouquier, L., Dubois, B., & Agid, Y. (1983) · Brain Research · doi:10.1016/0006-8993(83)90993-9 · Cited by 727
Muakkassa, K. F., & Strick, P. L. (1979) · Brain Research · doi:10.1016/0006-8993(79)90928-4 · Cited by 630
Afferent and efferent projections of the inferior area 6 in the macaque monkey
Matelli, M., Camarda, R., Glickstein, M., & Rizzolatti, G. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902510302 · Cited by 525
REACTION TIME IN PARKINSON'S DISEASE
Evarts, E. V., Teräväinen, H., & Calne, D. B. (1981) · Brain · doi:10.1093/brain/104.1.167 · Cited by 515
Tramu, G., Pillez, A., & Léonardelli, J. (1978) · Journal of Histochemistry & Cytochemistry · doi:10.1177/26.4.207771 · Cited by 506
Hendry, S., Jones, E. G., & Emson, P. C. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-10-02497.1984 · Cited by 415
Organization of catecholamine neurons projecting to the frontal cortex in the rat
Lindvall, O., Björklund, A., & Divac, I. (1978) · Brain Research · doi:10.1016/0006-8993(78)90173-7 · Cited by 412
Flagged first, then by citations
Research works printed but not linked: 12
- Berger B., 1976, Axones catecholaminergiques du cortex cérébral humain. Observation, en histofluorscence, de biopsiescérébrales dont 2 cas de maladie d'Alzheimer, Rev. Neurol., 132, 183
- Berger B., 1980, Enzymes and Neurotransmitters in Mental Disease, 317
- Berger B., 1986, Differential distribution of dopamine and serotonin axons in monkey cerebral cortex. A radioautographic study, Neurosci. Lett. Suppl., 26, S105
- Burke W. J., 1987, Geriatrics Clinical Pharmacology, 47
- Hökfelt T., 1977, Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat. IITyrosine‐hydroxylase in the telencephalon, Med. Bio., 55, 21
- Hökfelt T., 1984, Handbook of Chemical Neuroanatomy, 277
- Javoy‐Agid F., 1987, Distribution of monoaminergic, cholinergic and peptidergic markers in the human cerebral cortex, Soc. Neurosci. Abstr., 13, 527
- Kitt C. A., 1984, Contribution of catecholaminergic systems to neurites in plaques of aged primates, Ann. Neurol., 16, 118
- Mann D. M. A., 1983, The pathology of the human locus coeruleus, Clinical Neuropathol., 2, 1
- Marin‐Padilla M., 1986, Cerebral Cortex, 447
- Sanidés F., 1964, The cyto‐myeloarchitecture of the human frontal lobe, its relation to phylogenetic differentiation of the cerebral cortex, J. für Hirnforsch., 6, 269
- Von Economo C. V., 1972, L'architecture cellulaire normale de l'écorce cérébrale
Cited by
Sorted by citations
Items 201–300 of 395
Spiess, M., Bernardi, G., Kurth, S., Ringli, M., Wehrle, F. M., Jenni, O. G., Huber, R., & Siclari, F. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.05.024 · Cited by 37
Localization of pontine PGO wave generation sites and their anatomical projections in the rat
Datta, S., Siwek, D. F., Patterson, E. H., & Cipolloni, P. B. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199812)30:4 · Cited by 162
Morphology and distribution of neuropeptide-containing neurons in human cerebral cortex
Hornung, J., de Tribolet, N., & Törk, I. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90321-r · Cited by 36
Schulz‐Heik, R. J., Schaer, M., D, S. E. M., Hallmayer, J. F., Lin, X., Kaloupek, D. G., & Woodward, S. H. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.06.012 · Cited by 35
de Haes, J. I. U., Maguire, R. P., Jager, P. L., Paans, A. M. J., & den Boer, J. A. (2006) · Human Brain Mapping · doi:10.1002/hbm.20293 · Cited by 37
Yılmaz, O., Şengül, Y., Sengul, H., Yıldız, F. B. P., & Öztürk, A. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s174552 · Cited by 35
Belief about Nicotine Modulates Subjective Craving and Insula Activity in Deprived Smokers
Gu, X., Lohrenz, T. M., Salas, R., Baldwin, P. R., Soltani, A., Kirk, U., Cinciripini, P. M., & Montague, P. R. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00126 · Cited by 33
Dopamine Modulation of Motor and Sensory Cortical Plasticity among Vertebrates
Macêdo-Lima, M., & Remage‐Healey, L. (2021) · Integrative and Comparative Biology · doi:10.1093/icb/icab019 · Cited by 38
Serra, L., D’Amelio, M., Esposito, S., Domenico, C. D., Koch, G., Marra, C., Mercuri, N. B., Caltagirone, C., Artusi, C. A., Lopiano, L., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210171 · Cited by 34
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Alm, P. A. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.662204 · Cited by 35
Porges, E. C., & Decety, J. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00447 · Cited by 34
Haapalinna, A., Leino, T., & Heinonen, E. H. (2003) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-003-0827-z · Cited by 34
Dopamine D2 Receptor and N-Methyl-D-Aspartate Receptor 2B Subunit Genetic Variants and Intelligence
Tsai, S., Yu, Y. W. ‐., Lin, C., Chen, T.-J., Chen, S.-P., & Hong, C. (2002) · Neuropsychobiology · doi:10.1159/000054951 · Cited by 33
Haber, S. N., & Gdowski, M. (2004) · Elsevier eBooks · doi:10.1016/b978-012547626-3/50022-3 · Cited by 33
Expression and distribution of two isoforms of tyrosine hydroxylase in macaque monkey brain
Lewis, D. A., Melchitzky, D. S., & Haycock, J. W. (1994) · Brain Research · doi:10.1016/0006-8993(94)91360-9 · Cited by 33
Activation of specific cortical regions by apomorphine: an [15O]H2O PET study in humans
Kapur, S., Meyer, J., Wilson, A. A., Houle, S., & Brown, G. M. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90861-3 · Cited by 33
Sutoo, D., Akiyama, K., Yabe, K., & Kohno, K. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90170-8 · Cited by 32
Development of dopamine‐beta hydroxylase—positive fiber innervation of the rat hippocampus
Moudy, A. M., Kunkel, D. D., & Schwartzkroin, P. A. (1993) · Synapse · doi:10.1002/syn.890150407 · Cited by 32
Reward signals in the motor cortex: from biology to neurotechnology
Derosière, G., Shokur, S., & Vassiliadis, P. (2025) · Nature Communications · doi:10.1038/s41467-024-55016-0 · Cited by 30
Herregodts, P., Ebinger, G., & Michotte, Y. M. (1991) · Brain Research · doi:10.1016/0006-8993(91)91582-l · Cited by 31
Transcriptomic Characterization of the Human Insular Cortex and Claustrum
Ibrahim, C., Foll, B. L., & French, L. (2019) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2019.00094 · Cited by 31
Chapter VIII Primate cingulate cortex chemoarchitecture and its disruption in Alzheimer's disease
Vogt, B. A., Vogt, L. J., Nimchinsky, E. A., & Hof, P. R. (1997) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(97)80010-3 · Cited by 32
Hof, P. R., Glezer, I. I., Revishchin, A. V., Bouras, C., Charnay, Y., & Morgane, P. J. (1995) · Brain Research Bulletin · doi:10.1016/0361-9230(94)00202-c · Cited by 30
Parkinsonian patients report blunted subjective effects of methylphenidate.
Persico, A. M., Reich, S., Henningfield, J. E., Kuhar, M. J., & Uhl, G. R. (1998) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.6.1.54 · Cited by 30
Althaus, M., Groen, Y., Wijers, A. A., Minderaa, R. B., Kema, I. P., Dijck-Brouwer, J., & Hoekstra, P. J. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.04.007 · Cited by 29
Antipsychotic regulation of hippocampal dopamine receptor messenger RNA expression
Ritter, L. M., & Meador‐Woodruff, J. H. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00186-8 · Cited by 29
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Brabander, B. D., Boone, C., & Gerits, P. (1992) · Perceptual and Motor Skills · doi:10.2466/pms.1992.75.1.131 · Cited by 29
Dysfunction of motor cortices in Parkinson’s disease
Chu, H., Smith, Y., Lytton, W. W., Grafton, S. T., Villalba, R. M., Masilamoni, G. J., & Wichmann, T. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae294 · Cited by 32
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Stough, C. K. K., Thompson, J. C., Bates, T. C., & Nathan, P. J. (2001) · Intelligence · doi:10.1016/s0160-2896(01)00077-0 · Cited by 30
Lewis, D. A., & Harris, H. W. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90014-k · Cited by 28
Tyrosine hydroxylase—immunoreactive neurons in the temporal lobe in complex partial seizures
Zhu, Z., Armstrong, D. L., Grossman, R. G., & Hamilton, W. J. (1990) · Annals of Neurology · doi:10.1002/ana.410270518 · Cited by 28
Basal ganglia oscillations as biomarkers for targeting circuit dysfunction in Parkinson's disease
Petersson, P., Kühn, A. A., Neumann, W., & Fuentes, R. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.02.002 · Cited by 27
Polydopamine Sensors of Bacterial Hypoxia via Fluorescence Coupling
Lee, J. H., Ryu, J. S., Kang, Y. K., Lee, H., & Chung, H. J. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202007993 · Cited by 28
Thorstensen, J. R., Henderson, T. T., & Kavanagh, J. J. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109761 · Cited by 26
Okita, K., Ghahremani, D. G., Payer, D. E., Robertson, C. L., Mandelkern, M. A., & London, E. D. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv129 · Cited by 27
Cortical dopamine in schizophrenia: Strategies for postmortem studies
Lewis, D. A., & Akil, M. (1997) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(96)00057-x · Cited by 26
Task-related hemodynamic responses are modulated by reward and task engagement
Cardoso, M. M. B., Lima, B., Sirotin, Y. B., & Das, A. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000080 · Cited by 27
The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing
Wang, K. S., Zegel, M., Molokotos, E. K., Moran, L. V., Olson, D. P., Pizzagalli, D. A., & Janes, A. C. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0611-5 · Cited by 30
Acquisition and Performance of Delayed-response Tasks: a Neural Network Model
Gisiger, T., Kerszberg, M., & Changeux, J. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh149 · Cited by 24
Learning and forgetting processes in Parkinson's disease:
FAGLIONI, P., Botti, C., Scarpa, M., Ferrari, V., & Saetti, M. C. (1997) · Neuropsychologia · doi:10.1016/s0028-3932(96)00125-x · Cited by 25
de la Cruz, F., Wagner, G., Schumann, A., Suttkus, S., Güllmar, D., Reichenbach, J. R., & Bär, K. (2020) · Human Brain Mapping · doi:10.1002/hbm.25264 · Cited by 23
Verney, C. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.08.002 · Cited by 24
Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats
Hall, B. J., Slade, S. K., Allenby, C. E., Kutlu, M. G., & Levin, E. D. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.03.005 · Cited by 26
Cocker, P. J., Lin, M.-Y., Barrus, M. M., Foll, B. L., & Winstanley, C. A. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4355-1 · Cited by 24
Charlton, B. G., McGadey, J., Russell, D., & Neal, D. E. (1992) · Europe PMC (PubMed Central) · Cited by 24
Functional Anatomy and Physiology of the Basal Ganglia: Non-motor Functions
Haber, S. N. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-360-8_2 · Cited by 23
Bradberry, C. W. (2008) · Reviews in the Neurosciences · doi:10.1515/revneuro.2008.19.2-3.113 · Cited by 23
Mapping of serotonin 5-HT4 receptor mRNA and ligand binding sites in the post-mortem human brain
Bonaventure, P., Hall, H., Gommeren, W., Cras, P. P., Langlois, X., Jurzak, M., & Leysen, J. E. (2000) · Synapse · doi:10.1002/(sici)1098-2396(200004)36:1 · Cited by 107
Radisavljevic, Z., Cepeda, C., Peacock, W. J., Buchwald, N. A., & Levine, M. S. (1994) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(94)90085-x · Cited by 23
Cocker, P. J., Hosking, J. G., Murch, W. S., Clark, L., & Winstanley, C. A. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.01.019 · Cited by 22
Neural correlates of primary and reflective consciousness of spatial orienting
Bartolomeo, P., Zieren, N., Vohn, R., Dubois, B., & Sturm, W. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.07.005 · Cited by 22
Astrocyte expression of D2-like dopamine receptors in the prefrontal cortex
Mladinov, M., Mayer, D., Brčić, L., Wolstencroft, E. C., Mân, N. T., Holt, I., Hof, P. R., Morris, G., & Šimić, G. (2010) · Translational Neuroscience · doi:10.2478/v10134-010-0035-6 · Cited by 22
The locus coeruleus in schizophrenia: a postmortem study of noradrenergic neurones
Craven, R., Priddle, T. H., Crow, T. J., & Esiri, M. M. (2005) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2004.00597.x · Cited by 21
Immunohistochemical localization of dopamine-ß-hydroxylase in human and monkey eyes
Chen, Z. Z., Jia, W. W., Kaufman, P. L. P., Kaufman, P. L. P., & Cynader, M. S. (1999) · Current Eye Research · doi:10.1076/ceyr.18.1.39.5391 · Cited by 21
Neuronal localization of tyrosine hydroxylase gene products in human neocortex
Lewis, D. A., Melchitzky, D. S., Gioio, A. E., Solomon, Z., & Kaplan, B. B. (1991) · Molecular and Cellular Neuroscience · doi:10.1016/1044-7431(91)90049-t · Cited by 21
Watakabe, A., Fujita, H., Hayashi, M., & Yamamori, T. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00177.x · Cited by 21
Chapter 2 Neurotransmitters in the cerebral cortex
Parnavelas, J. G. (1991) · Progress in brain research · doi:10.1016/s0079-6123(08)62674-6 · Cited by 21
Dopaminergic modulation of emotional conflict in Parkinson's disease
Fleury, V., Cousin, É., Czernecki, V., Schmitt, E., Lhommée, E., Poncet, A., Fraix, V., Troprés, I., Pollak, P., Krainik, A., et al. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00164 · Cited by 22
Differential magnitude coding of gains and omitted rewards in the ventral striatum
Pedroni, A., Koeneke, S., Velickaite, A., & Jäncke, L. (2011) · Brain Research · doi:10.1016/j.brainres.2011.07.019 · Cited by 21
Development of the human cerebral cortex: A histochemical study
Tiu, S. C., Yew, D. T. W., & Chan, W. Y. (2002) · Progress in Histochemistry and Cytochemistry · doi:10.1016/s0079-6336(02)80002-x · Cited by 20
Gebhard, R., Zilles, K., Schleicher, A., Everitt, B. J., Robbins, T. W., & Divac, I. (1995) · Anatomy and Embryology · doi:10.1007/bf00186741 · Cited by 20
Impact of frontal lobe lesions on rehabilitation and recovery from acute brain injury
Eslinger, P. J., Grattan, L. M., & Geder, L. (1995) · NeuroRehabilitation · doi:10.3233/nre-1995-5206 · Cited by 73
Processing of Positive and Negative Feedback in Patients with Cerebellar Lesions
Rustemeier, M., Koch, B., Schwarz, M., & Bellebaum, C. (2015) · The Cerebellum · doi:10.1007/s12311-015-0702-8 · Cited by 18
Trottier, S., Evrard, B., Biraben, A., & Chauvel, P. (1994) · Epilepsy Research · doi:10.1016/0920-1211(94)90026-4 · Cited by 19
Prenatal Monoaminergic Innervation of the Cerebral Cortex: Differences between Rodents and Primates
Berger, B., Verney, C., & Goldman-Rakic, P. S. (1992) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4684-6805-2_2 · Cited by 19
Self-citation5 Dopaminergic Modulation of Cognition in Human Aging
Li, S., Lindenberger, U., Nyberg, L. H., Heekeren, H. R., & Bäckman, L. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195328875.003.0005 · Cited by 20
Ji, N., Shuai, L., Chen, Y., Liu, L., Li, H.-M., Li, Z.-H., Yang, L., Qian, Q., Tang, Y.-L., Cubells, J., et al. (2011) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31215 · Cited by 14
Perrin, D., Mamet, J., Scarna, H., Roux, J., Bérod, A., & Dalmaz, Y. (2004) · Synapse · doi:10.1002/syn.20065 · Cited by 18
Synaptology of Dopamine Neurons
Sesack, S. R. (2002) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-56051-4_4 · Cited by 18
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Sindermann, C., Luo, R., Zhang, Y., Kendrick, K. M., Becker, B., & Montag, C. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00148 · Cited by 19
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Berger, B., Gaspar, P., & Verney, C. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb27359.x · Cited by 17
Self-citationPossible role of locus coeruleus neuronal loss in age-related memory and attention deficits
Gargano, A., Olabiyi, B. F., Palmisano, M., Zimmer, A., & Bilkei‐Gorzó, A. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1264253 · Cited by 17
An integrative analysis of regional gene expression profiles in the human brain
Myers, E. M., Bartlett, C. W., Machiraju, R., & Bohland, J. W. (2014) · Methods · doi:10.1016/j.ymeth.2014.12.010 · Cited by 16
Frequency analysis of catecholamine axonal morphology in human brain
Booze, R. M., Mactutus, C. F., Gutman, C. R., & Davis, J. N. (1993) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(93)90197-7 · Cited by 16
Koehler, S., Wacker, J., Odorfer, T., Reif, A., Gallinat, J., Fallgatter, A. J., & Herrmann, M. J. (2011) · Biological Psychology · doi:10.1016/j.biopsycho.2011.05.006 · Cited by 15
Sutoo, D., Akiyama, K., & Yabe, K. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02271-0 · Cited by 15
Developmental Neurobiology: Implications for Pediatric Psychopharmacology
CARREY, N. J. (2001) · The Canadian Journal of Psychiatry · doi:10.1177/070674370104600904 · Cited by 15
Widespread Autonomic Physiological Coupling Across the Brain-Body AxisPreprint
Bolt, T., Wang, S., Nomi, J. S., Setton, R., Gold, B. P., Frederick, B. B., Yeo, B. T. T., Chen, J. J., Picchioni, D., Spreng, R. N., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.19.524818 · Cited by 15
Rustemeier, M., Schwabe, L., & Bellebaum, C. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.01.009 · Cited by 15
Foote, S. L. (1997) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(97)80006-1 · Cited by 14
Chemical neuroanatomy of the hippocampal formation and the perirhinal and parahippocampal cortices
Kobayashi, Y., & Amaral, D. G. (1999) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(99)80026-8 · Cited by 14
Hurd, Y. L., & Hall, H. (2005) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(05)80013-2 · Cited by 14
Age-Related Cognitive Deficits and Neurotransmitters
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Harper, M. S., & Wallace, M. N. (1995) · Europe PMC (PubMed Central) · Cited by 13
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Hornung, J., & de Tribolet, N. (1995) · Advances in behavioral biology · doi:10.1007/978-1-4615-1853-2_4 · Cited by 12
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Gisiger, T., & Kerszberg, M. (2005) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020025 · Cited by 11
Gargano, A., Beins, E. C., Zimmer, A., & Bilkei‐Gorzó, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010005 · Cited by 10
Schaaff, N., Karch, S., Segmiller, F. M., Koch, W., Reicherzer, M., Mulert, C., Hegerl, U., Juckel, G., & Pogarell, O. M. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.03.051 · Cited by 10
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Lewis, D. A. (1990) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(90)90025-c · Cited by 10
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Metadata
- Authors
- Gaspar, P., Berger, B., Febvret, A., Vigny, A., & Henry, J. P.
- Affiliations
- Inserm (FR)
- Institut de Biologie Physico-Chimique (FR)
- Venue
- Journal of Comparative Neurology
- Publisher
- Wiley
- Published
- 1989-01-08
- Volume
- 279
- Issue
- 2
- Pages
- 249-271
- ISSN
- 0021-9967 (ISSN-L)
- 1096-9861
- OpenAlex
- W2069412440
- Cited by
- 395
- References
- 79
- Citations by year
- 2026: 4 · 2025: 11 · 2024: 7 · 2023: 8 · 2022: 5 · 2021: 14 · 2020: 13 · 2019: 9 · 2018: 9 · 2017: 11 · 2016: 8 · 2015: 11 · 2014: 11 · 2013: 12 · 2012: 9
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Comparative Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- catecholamine innervation, human cerebral cortex, noradrenergic innervation, dopaminergic innervation, tyrosine hydroxylase, dopamine beta-hydroxylase, cortical laminar distribution, cytoarchitectonic areas, molecular layer, neocortex, limbic cortex, norepinephrine, postmortem brain
- MeSH terms
- Adult, Aged, Aged, 80 and over, Catecholamines, Cerebral Cortex, Dopamine beta-Hydroxylase, Female, Humans, Immunohistochemistry, Male, Middle Aged, Nerve Fibers, Tyrosine 3-Monooxygenase
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