What is the association between traumatic life events and alcohol abuse/dependence in people with and without PTSD? Findings from a nationally representative sample
Abstract
BACKGROUND: Approximately 60-90% of the general population will experience a traumatic event during their lifetime. However, relatively few will develop a trauma-related psychological disorder. Possible psychological sequelae of trauma include posttraumatic stress disorder (PTSD) and alcohol-use disorders (AUDs). While AUDs often occur in the context of PTSD, little is known about the degree to which AUDs are attributable to specific traumatic events. The purpose of the present investigation was to assess the degree to which specific traumatic events are predictive of AUDs in people with and without PTSD. METHODS: The current sample was selected from the National Epidemiological Survey of Alcohol and Related Conditions (NESARC; N = 34,160), a nationally representative sample of American adults. Multiple logistic regressions were performed to examine odds ratios of 27 traumatic events among individuals with and without PTSD in the prediction of AUD diagnoses. RESULTS: Results indicated significant positive odds ratios among individuals meeting criteria for PTSD and having experienced a childhood trauma (OR = 1.40 [95% CI: 1.08-1.83], P<.01) or assaultive violence (OR = 1.41 [95% CI: 1.13-1.77], P<.01) for predicting AUDs. Also, among individuals without PTSD, childhood trauma (OR = 1.32 [95% CI: 1.23-1.41], P<.001), assaultive violence (OR = 1.42 [95% CI: 1.13-1.78], P<.001), unexpected death (OR = 1.19 [95% CI: 1.12-1.28], P<.001), and learning of trauma (OR = 1.22 [95% CI: 1.13-1.30], P<.001) positively predicted the presence of AUDs. CONCLUSIONS: Results indicate significant positive relationships between traumatic events and AUDs, particularly among individuals without PTSD. Specific associations and theoretical implications will be discussed.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Exposure to potentially traumatic events is associated with increased risk for developing mental disorders, including PTSD, MDD, PD, GAD, SAD, and AUD.
“Such exposures have been associated with increased risk for the development of mental disorders, including posttraumatic stress disorder (PTSD),2 major depressive disorder (MDD),5 panic disorder (PD), generalized anxiety disorder (GAD), and social anxiety disorder (SAD), as well as vulnerability for an alcohol use disorder (AUD).6,7”
From Mental Disorder Symptoms among Public Safety Personnel in Canada (2018) · cites this paper as [7]
Cites
Combat Duty in Iraq and Afghanistan, Mental Health Problems, and Barriers to Care
Hoge, C. W., Castro, C. A., Messer, S. C., McGurk, D., Cotting, D. I., & Koffman, R. L. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040603 · Cited by 4,778 · see citing works
Grant, B. F., Stinson, F. S., Dawson, D. A., Chou, S. P., Dufour, M. C., Compton, W., Pickering, R. P., & Kaplan, K. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.8.807 · Cited by 2,889 · see citing works
Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
Kessler, R. C., McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., Aguilar-Gaxiola, S., Alhamzawi, A. O., Alonso, J., Angermeyer, M., et al. (2010) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.080499 · Cited by 2,640 · see citing works
Dube, S. R., Felitti, V. J., Dong, M., Chapman, D. P., Giles, W. H., & Anda, R. F. (2003) · Pediatrics · doi:10.1542/peds.111.3.564 · Cited by 2,333 · see citing works
Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering, R. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(03)00070-x · Cited by 1,110 · see citing works
Substance Use Disorders in Patients With Posttraumatic Stress Disorder: A Review of the Literature
Jacobsen, L. K., Southwick, S. M., & Kosten, T. R. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.8.1184 · Cited by 1,050 · see citing works
Perkonigg, A., Kessler, R. C., Storz, S., & Wïttchen, H. (2000) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2000.101001046.x · Cited by 971 · see citing works
The Psychiatric Sequelae of Traumatic Injury
Bryant, R. A., O'Donnell, M. L., Creamer, M., McFarlane, A. C., Clark, C. R., & Silove, D. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09050617 · Cited by 843 · see citing works
Epidemiologic Studies of Trauma, Posttraumatic Stress Disorder, and other Psychiatric Disorders
Breslau, N. (2002) · The Canadian Journal of Psychiatry · doi:10.1177/070674370204701003 · Cited by 622 · see citing works
Breslau, N., Davis, G. C., & Schultz, L. R. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.289 · Cited by 573 · see citing works
Afifi, T. O., Enns, M. W., Cox, B. J., Asmundson, G. J. G., Stein, M. B., & Sareen, J. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.120253 · Cited by 558 · see citing works
Self-citationRuan, W. J., Goldstein, R. B., Chou, S. P., Smith, S. M., Saha, T. D., Pickering, R. P., Dawson, D. A., Huang, B., Stinson, F. S., & Grant, B. F. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.06.001 · Cited by 557 · see citing works
Trauma exposure and stress-related disorders in inner city primary care patients
Gillespie, C. F., Bradley, B., Mercer, K., Smith, A. K., Conneely, K. N., Gapen, M., Weiss, T., Schwartz, A. C., Cubells, J. F., & Ressler, K. J. (2009) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2009.05.003 · Cited by 504 · see citing works
Khoury, L., Tang, Y. L., Bradley, B., Cubells, J. F., & Ressler, K. J. (2010) · Depression and Anxiety · doi:10.1002/da.20751 · Cited by 488 · see citing works
Investigations of causal pathways between ptsd and drug use disorders
Chilcoat, H. D., & Breslau, N. (1998) · Addictive Behaviors · doi:10.1016/s0306-4603(98)00069-0 · Cited by 367 · see citing works
Leeies, M., Pagura, J., Sareen, J., & Bolton, J. M. (2010) · Depression and Anxiety · doi:10.1002/da.20677 · Cited by 300 · see citing works
Self-citationEpidemiological evidence about the relationship between ptsd and alcohol abuse
McFARLANE, A. C. (1998) · Addictive Behaviors · doi:10.1016/s0306-4603(98)00098-7 · Cited by 259 · see citing works
Chatterji, S., Saunders, J. B., Vrasti, R., Grant, B. F., Hasin, D. S., & Mager, D. E. (1997) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(97)00088-4 · Cited by 247 · see citing works
The Course of PTSD, Major Depression, Substance Abuse, and Somatization After a Natural Disaster
North, C., Kawasaki, A., Spitznagel, E., & Hong, B. (2004) · Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000146911.52616.22 · Cited by 241 · see citing works
Bray, R. M., & Hourani, L. L. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01841.x · Cited by 204 · see citing works
The co-occurrence of substance use and high-risk behaviors
Baskin-sommers, A. R., & Sommers, I. B. (2006) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2005.07.010 · Cited by 182 · see citing works
Stevens, S. J., Murphy, B. S., & McKnight, K. (2003) · Child Maltreatment · doi:10.1177/1077559502239611 · Cited by 114 · see citing works
Flory, K., Hankin, B., Kloos, B., Cheely, C., & Turecki, G. (2009) · Substance Use & Misuse · doi:10.3109/10826080902962128 · Cited by 108 · see citing works
Grassi-Oliveira, R., & Stein, L. M. (2008) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2008.05.008 · Cited by 80 · see citing works
Schäfer, I., Reininghaus, U., Langeland, W., Voss, A., Zieger, N., Haasen, C., & Karow, A. (2007) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2007.05.013 · Cited by 69 · see citing works
Sartor, C. E., Lynskey, M. T., Bucholz, K. K., McCutcheon, V. V., Nelson, E. C., Waldron, M., & Heath, A. C. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.12.022 · Cited by 66 · see citing works
O’Hare, T., Shen, C., & Sherrer, M. V. (2010) · Journal of Traumatic Stress · doi:10.1002/jts.20515 · Cited by 44 · see citing works
Conrad, K. J., Bezruczko, N., Chan, Y.-F., Riley, B., Diamond, G. S., & Dennis, M. L. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.07.023 · Cited by 38 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Katzman, M. A., Bleau, P., Blier, P., Chokka, P., Kjernisted, K., Van Ameringen, M., & the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-s1-s1 · Cited by 1,090 · see citing works
“An estimated 75% of patients with PTSD have another comorbid psychiatric disorder [3,848]; and rates are particularly high for other anxiety and related disorders [3,849,859,869,870], MDD [3,849,859,871,872], oppositional defiant disorder [3], ADHD [3], SUD [849], alcohol dependence [3,873], and borderline personality…”
BackgroundMental Disorder Symptoms among Public Safety Personnel in Canada
Carleton, R. N., Afifi, T. O., Turner, S., Taillieu, T., Duranceau, S., LeBouthillier, D. M., Sareen, J., Ricciardelli, R., MacPhee, R. S., Groll, D., et al. (2018) · The Canadian Journal of Psychiatry · doi:10.1177/0706743717723825 · Cited by 558 · see citing works
“Such exposures have been associated with increased risk for the development of mental disorders, including posttraumatic stress disorder (PTSD),(2) major depressive disorder (MDD),(5) panic disorder (PD), generalized anxiety disorder (GAD), and social anxiety disorder (SAD), as well as vulnerability for an alcohol use…”
BackgroundSelf-citationPosttraumatic Stress Disorder in Adults: Impact, Comorbidity, Risk Factors, and Treatment
Sareen, J. (2014) · The Canadian Journal of Psychiatry · doi:10.1177/070674371405900902 · Cited by 467 · see citing works
Self-citationHasin, D. S., & Grant, B. F. (2015) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-015-1088-0 · Cited by 452 · see citing works
Assessing the Relative Impact of Diverse Stressors among Public Safety Personnel
Carleton, R. N., Afifi, T. O., Taillieu, T., Turner, S., Mason, J. E., Ricciardelli, R., McCreary, D. R., Vaughan, A. D., Anderson, G. S., Krakauer, R. L., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17041234 · Cited by 225 · see citing works
“Research has also demonstrated that PPTE exposure is associated with an increased risk of negative mental health outcomes, such as symptoms of posttraumatic stress disorder (PTSD; [2]), major depressive disorder (MDD; [6]) panic disorder (PD; [7]), generalized anxiety disorder (GAD; [8]), social anxiety disorder (SAD;…”
BackgroundRicciardelli, R., Carleton, R. N., Mooney, T., & Cramm, H. (2020) · Health: An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine · doi:10.1177/1363459318800167 · Cited by 148 · see citing works
PTSD symptom severity and impulsivity among firefighters: Associations with alcohol use
Bartlett, B. A., Smith, L. J., Lebeaut, A., Tran, J. K., & Vujanovic, A. A. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.06.039 · Cited by 30 · see citing works
Müller, M., Vandeleur, C., Rodgers, S., Rössler, W., Castelao, E., Preisig, M., & Ajdacic-Gross, V. (2015) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2015.03.006 · Cited by 28 · see citing works
- Authors
- Fetzner, M. G., McMillan, K. A., Sareen, J., & Asmundson, G. J. G.
- Affiliations
- University of Regina (CA)
- Venue
- Depression and Anxiety
- Publisher
- Hindawi Limited
- Published
- 2011-07-18
- Volume
- 28
- Issue
- 8
- Pages
- 632-638
- ISSN
- 1091-4269 (ISSN-L)
- OpenAlex
- W2054933439
- Cited by
- 137
- References
- 28
- Citations by year
- 2026: 3 · 2025: 13 · 2024: 7 · 2023: 8 · 2022: 7 · 2021: 7 · 2020: 7 · 2019: 6 · 2018: 16 · 2017: 11 · 2016: 11 · 2015: 11 · 2014: 13 · 2013: 12 · 2012: 4
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Keywords
- traumatic life events, alcoholism, post-traumatic stress disorder, childhood trauma, assaultive violence, unexpected death, trauma exposure
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Alcoholism, Female, Health Surveys, Humans, Interview, Psychological, Life Change Events, Male, Mental Health Services, Middle Aged, Risk Factors, Stress Disorders, Post-Traumatic, United States, Comorbidity, Prevalence, Substance-Related Disorders, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review