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T‐box genes in early embryogenesis

Open access
Showell, Chris, Binder, Olav, Conlon, Frank L.·2004·Developmental Dynamics

Abstract

The T‐box gene family, encoding related DNA‐binding transcriptional regulators, plays an essential role in controlling many aspects of embryogenesis in a wide variety of organisms. The T‐box genes exhibit diverse patterns of spatial and temporal expression in the developing embryo, and both genetic and molecular embryological studies have demonstrated their importance in regulating cell fate decisions that establish the early body plan, and in later processes underlying organogenesis. Despite these studies, little is known of either the regulation of the T‐box genes or the identities of their transcriptional targets. The aim of this review is to examine the diverse yet conserved roles of several T‐box genes in regulating early patterning in chordates and to discuss possible mechanisms through which this functional diversity might arise. Developmental Dynamics 229:201–218, 2004. © 2003 Wiley‐Liss, Inc.

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Metadata

Authors
Showell, C., Binder, O., & Conlon, F. L.
Venue
Developmental Dynamics
Publisher
Wiley
Published
2003-12-10
Volume
229
Issue
1
Pages
201-218
ISSN
  • 1058-8388 (ISSN-L)
  • 1097-0177
OpenAlex
W2132669667
Cited by
296
References
6
FWCI
4.29
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: T‐box genes in early embryogenesis. https://app.cochat.ai/papers/10.1002/dvdy.10480
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Showell, C., Binder, O., & Conlon, F. L. (2004). T‐box genes in early embryogenesis. Developmental Dynamics. https://doi.org/10.1002/dvdy.10480

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