The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Crosstalk between Wnt and bone morphogenic protein signaling: A turbulent relationship
Open accessAbstract
The Wnt and the bone morphogenic protein (BMP) pathways are evolutionarily conserved and essentially independent signaling mechanisms, which, however, often regulate similar biological processes. Wnt and BMP signaling are functionally integrated in many biological processes, such as embryonic patterning in Drosophila and vertebrates, formation of kidney, limb, teeth and bones, maintenance of stem cells, and cancer progression. Detailed inspection of regulation in these and other tissues reveals that Wnt and BMP signaling are functionally integrated in four fundamentally different ways. The molecular mechanism evolved to mediate this integration can also be summarized in four different ways. However, a fundamental aspect of functional and mechanistic interaction between these pathways relies on tissue‐specific mechanisms, which are often not conserved and cannot be extrapolated to other tissues. Integration of the two pathways contributes toward the sophisticated means necessary for creating the complexity of our bodies and the reliable and healthy function of its tissues and organs. Developmental Dynamics 239:16–33, 2010. © 2009 Wiley‐Liss, Inc.
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Cites
WNT and β-catenin signalling: diseases and therapies
Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1427 · Cited by 1,763
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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
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High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5
Boyden, L. M., Mao, J., Belsky, J., Mitzner, L., Farhi, A., Mitnick, M. A., Wu, D., Insogna, K., & Lifton, R. P. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013444 · Cited by 1,591
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling
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Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors
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Bouwmeester, T., Kim, S.-H., Sasai, Y., Lu, B., & Robertis, E. M. D. (1996) · Nature · doi:10.1038/382595a0 · Cited by 759 · cited 1×
“Cerberus, a secreted molecule isolated as a head inducer in Xenopus (Bouwmeester et al., 1996), has been shown to bind BMP, Nodal, and Wnt ligands and to inhibit these signals.”
BackgroundEssential role of β-catenin in postnatal bone acquisition.
Holmen, S. L., Zylstra, C. R., Mukherjee, A., Sigler, R. E., Faugere, M.-C., Bouxsein, M. L., Deng, L., Clemens, T. L., & Williams, B. O. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501900200 · Cited by 584
Distinct WNT Pathways Regulating AER Formation and Dorsoventral Polarity in the Chick Limb Bud
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Wise, a context-dependent activator and inhibitor of Wnt signalling
Itasaki, N., Jones, C. M., Mercurio, S., Rowe, A., Domingos, P. M., Smith, J. C., & Krumlauf, R. (2003) · Development · doi:10.1242/dev.00674 · Cited by 321
Self-citation
Cited by
Building Muscle: Molecular Regulation of Myogenesis
Bentzinger, C. F., Wang, Y. X., & Rudnicki, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008342 · Cited by 1,195
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
Takebe, N., Harris, P. J., Warren, R. Q., & Ivy, S. P. (2011) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2010.196 · Cited by 992
Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling
Crane, J. L., & Cao, X. (2014) · Journal of Clinical Investigation · doi:10.1172/jci70050 · Cited by 448
Transforming growth factor‐β in stem cells and tissue homeostasis
Xu, X., Zheng, L., Yuan, Q., Zhen, G., Crane, J. L., Zhou, X., & Cao, X. (2018) · Bone Research · doi:10.1038/s41413-017-0005-4 · Cited by 414
Beyond TGFβ: roles of other TGFβ superfamily members in cancer
Wakefield, L. M., & Hill, C. S. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3500 · Cited by 374
Metadata
- Authors
- Itasaki, N., & Hoppler, S.
- Venue
- Developmental Dynamics
- Publisher
- Wiley
- Published
- 2009-06-19
- Volume
- 239
- Issue
- 1
- Pages
- 16-33
- ISSN
- 1058-8388 (ISSN-L)
- 1097-0177
- OpenAlex
- W1989610585
- Cited by
- 161
- References
- 10
- FWCI
- 4.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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