Heightened sensitivity to reward and punishment in anorexia nervosa
Open accessAbstract
Objective: The objective of this study is to test whether females with anorexia nervosa (AN) have increased sensitivity to punishing or rewarding stimuli, behaviors that could drive high self‐control and anxious, avoidant behaviors. Method: Sixty‐four females completed the study: 33 control females (CFs, mean age 19.7 years) and 31 females with AN (mean age 19.6 years). Participants completed diagnostic exams, questionnaires for eating disorder severity and personality, and the Sensitivity to Punishment/Sensitivity to Reward Questionnaire (SPSRQ). Results: Females with AN scored higher than CFs on SPSRQ sensitivity to punishment ( p < 0.00001) and sensitivity to reward ( p = 0.005). Females with AN without anxiety or depression continued to have increased SPSRQ scores compared to CFs. Discussion: This is the first study comparing the SPSRQ in females with AN and CFs. Results suggest that reward and punishment sensitivity are increased in females with AN and could be potential trait markers. It is possible that harm‐avoidant, anxious behaviors in females with AN are related to this heightened sensitivity. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:317–324)
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Individuals with AN report a heightened response to both punishment and reward outcome, even in the absence of clinically significant symptoms of anxiety or depression.
“Individuals with AN report a heightened response to both punishment and reward outcome, even in the absence of clinically significant symptoms of anxiety or depression [338].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [338]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders.
Widiger, T. A. (2000) · Oxford University Press eBooks · doi:10.1037/10518-009 · Cited by 19,767 · see citing works
Carver, C. S., & White, T. L. (1994) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.67.2.319 · Cited by 7,306 · see citing works
A psychobiological model of temperament and character
Cloninger, C. R. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820240059008 · Cited by 5,458 · see citing works
The psychophysiological basis of introversion-extraversion
Gray, J. A. (1970) · Behaviour Research and Therapy · doi:10.1016/0005-7967(70)90069-0 · Cited by 1,558 · see citing works
Torrubia, R., Ávila, C., Moltó, J., & Caseras, X. (2001) · Personality and Individual Differences · doi:10.1016/s0191-8869(00)00183-5 · Cited by 1,348 · see citing works
Eating Disorder Inventory-2 ; Pro-fessional Manual
Garner, D. (1991) · Medical Entomology and Zoology · Cited by 1,283 · see citing works
Comorbidity of Anxiety Disorders With Anorexia and Bulimia Nervosa
Kaye, W. H., Bulik, C. M., Thornton, L., Barbarich, N., Masters, K., & the Price Foundation Collaborative Group (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.12.2215 · Cited by 1,162 · see citing works
Mortality in anorexia nervosa.
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.7.1073 · Cited by 974 · see citing works
Personality and eating disorders: A decade in review
Cassin, S. E., & von Ranson, K. M. (2005) · Clinical Psychology Review · doi:10.1016/j.cpr.2005.04.012 · Cited by 832 · see citing works
The Reinforcement Sensitivity Theory of Personality
Corr, P. J. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511819384 · Cited by 691 · see citing works
Bijttebier, P., Beck, I., Claes, L., & Vandereycken, W. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.04.002 · Cited by 566 · see citing works
The personality theories of H.J. Eysenck and J.A. Gray: a comparative review
Matthews, G., & Gilliland, K. (1999) · Personality and Individual Differences · doi:10.1016/s0191-8869(98)00158-5 · Cited by 504 · cited 1× · see citing works
“Although the BIS/BAS has been applied the most frequently in behavioral, psychophysiological and neuro-imaging studies, some have criticized the scale’s approach towards measuring “generalized sensitivity to reward and punishment, while Gray’s theory deals with sensitivity to specific cues” (15-17).”
MethodA systematic review and meta-analysis of set-shifting ability in eating disorders
Roberts, M., Tchanturia, K., Stahl, D. R., Southgate, L., & Treasure, J. L. (2007) · Psychological Medicine · doi:10.1017/s0033291707009877 · Cited by 502 · see citing works
The DISC Predictive Scales (DPS): Efficiently Screening for Diagnoses
Lucas, C. P., Zhang, H., Fisher, P. W., Shaffer, D., Regier, D. A., Narrow, W. E., Bourdon, K. H., Dulcan, M. K., CANINO, G. J., Rubio‐Stipec, M., et al. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200104000-00013 · Cited by 370 · see citing works
Loxton, N. J., & Dawe, S. (2001) · International Journal of Eating Disorders · doi:10.1002/eat.1042 · Cited by 275 · see citing works
Heym, N., Ferguson, E., & Lawrence, C. (2008) · Personality and Individual Differences · doi:10.1016/j.paid.2008.07.013 · Cited by 255 · see citing works
Temperament and Character in Women with Anorexia Nervosa
Klump, K. L., Bulik, C. M., Pollice, C., Halmi, K. A., Fichter, M. M., Berrettini, W. H., Devlin, B., Strober, M. A., Kaplan, A. S., Woodside, D. B., et al. (2000) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200009000-00001 · Cited by 212 · see citing works
Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder
Davis, C., Levitan, R. D., Kaplan, A. S., Carter, J., Reid, C., Curtis, C., Patte, K., Hwang, R., & Kennedy, J. L. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.09.024 · Cited by 200 · see citing works
Personality characteristics of women before and after recovery from an eating disorder
KLUMP, K. L., STROBER, M., BULIK, C. M., THORNTON, L., JOHNSON, C., DEVLIN, B., FICHTER, M. M., HALMI, K. A., KAPLAN, A. S., BLAKE WOODSIDE, D., et al. (2004) · Psychological Medicine · doi:10.1017/s0033291704002442 · Cited by 194 · see citing works
Impulsiveness and lack of inhibitory control in eating disorders.
Claes, L., Nederkoorn, C., Vandereycken, W., Guerrieri, R., & Vertommen, H. (2006) · Eating Behaviors · doi:10.1016/j.eatbeh.2006.05.001 · Cited by 192 · see citing works
Treatment of anorexia nervosa: Insights and obstacles
Guarda, A. S. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.020 · Cited by 189 · see citing works
Barrós‐Loscertales, A., Meseguer, V., Sanjuán, A., Belloch, V., Parcet, M. A., Torrúbia, R., & Ávila, C. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.07.025 · Cited by 151 · see citing works
Beck, I. M. E., Smits, D., Claes, L., Vandereycken, W., & Bijttebier, P. (2009) · Personality and Individual Differences · doi:10.1016/j.paid.2009.04.007 · Cited by 120 · see citing works
O’Connor, R. M., Colder, C. R., & Hawk, L. W. (2004) · Personality and Individual Differences · doi:10.1016/j.paid.2003.11.008 · Cited by 106 · see citing works
Review of the Eating Disorder Inventory–3
Cumella, E. J. (2006) · Journal of Personality Assessment · doi:10.1207/s15327752jpa8701_11 · Cited by 95 · see citing works
Neuroimaging Studies in Eating Disorders
Frank, G. K., Bailer, U. F., Henry, S., Wagner, A., & Kaye, W. H. (2004) · CNS Spectrums · doi:10.1017/s1092852900009639 · Cited by 94 · see citing works
Self-citationLoxton, N. J., & Dawe, S. (2006) · Appetite · doi:10.1016/j.appet.2006.05.014 · Cited by 87 · see citing works
Personality and conditioning: A test of four models.
Zinbarg, R. E., & Revelle, W. (1989) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.57.2.301 · Cited by 79 · see citing works
Asymmetric Cognitive Function in Anorexia Nervosa
Maxwell, J. K., Tucker, D. M., & Townes, B. D. (1984) · International Journal of Neuroscience · doi:10.3109/00207458409079532 · Cited by 44 · see citing works
Lee, S. H., Ham, B., Cho, Y.-H., Lee, S.-M., & Shim, S. H. (2007) · Neuropsychobiology · doi:10.1159/000115781 · Cited by 39 · see citing works
Deriving behavioural phenotypes in an international, multi-centre study of eating disorders
THE PRICE FOUNDATION COLLABORATIVE GROUP (2001) · Psychological Medicine · doi:10.1017/s0033291701003671 · Cited by 31 · see citing works
Current Directions in Implicit Learning: Where is it that we Were Supposed to Go Again
Cleeremans, A., & Content, A. (1997) · Psychologica Belgica · doi:10.5334/pb.905 · Cited by 3 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- [12]Deary V Punishment, Reward and Personality: A review of Corry, P.J Personality and Individual Differences 2009 46 565 6
- [23]First MB Spitzer RL Gibbon M Williams JBW Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P) New York Biometrics Research New York State Psychiatric Institute 2002
Cited by
Sorted by citations
Lavender, J. M., Wonderlich, S. A., Engel, S. G., Gordon, K. H., Kaye, W. H., & Mitchell, J. E. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.05.010 · Cited by 512 · see citing works
“Evidence more clearly indicates that avoidance tendencies and punishment sensitivity are elevated in AN (Claes et al., 2006, 2010; Glashouwer et al., 2014; Harrison, et al., 2011; Jappe et al., 2011).”
BackgroundDichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299 · see citing works
Wierenga, C. E., Ely, A., Bischoff-Grethe, A., Bailer, U. F., Simmons, A. N., & Kaye, W. H. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00410 · Cited by 195 · see citing works
Advances from neuroimaging studies in eating disorders
Frank, G. K. W. (2015) · CNS Spectrums · doi:10.1017/s1092852915000012 · Cited by 144 · see citing works
Self-citationPsychopharmacological advances in eating disorders
Himmerich, H., & Treasure, J. (2018) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2018.1383895 · Cited by 119 · see citing works
An overview of trauma-informed care and practice for eating disorders
Brewerton, T. D. (2019) · Journal of Aggression, Maltreatment & Trauma · doi:10.1080/10926771.2018.1532940 · Cited by 111 · see citing works
Altered brain response to reward and punishment in adolescents with Anorexia nervosa
Bischoff-Grethe, A., McCurdy, D., Grenesko-Stevens, E., (Zoe) Irvine, L. E., Wagner, A., Wendy Yau, W.-Y., Fennema-Notestine, C., Wierenga, C. E., Fudge, J. L., Delgado, M. R., et al. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2013.07.004 · Cited by 99 · see citing works
Hildebrandt, T., Grotzinger, A., Reddan, M., Greif, R., Levy, I., Goodman, W., & Schiller, D. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.06.008 · Cited by 82 · see citing works
Stress hormones and eating disorders
Chami, R., Monteleone, A. M., Treasure, J., & Monteleone, P. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2018.12.009 · Cited by 66 · see citing works
Greater insula white matter fiber connectivity in women recovered from anorexia nervosa
Shott, M. E., Pryor, T. L., Yang, T. T., & Frank, G. K. W. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.172 · Cited by 62 · see citing works
Self-citationThe Role of Serious Video Games in the Treatment of Disordered Eating Behaviors: Systematic Review
Tang, W. S. W., Ng, T. J. Y., Wong, J. Z. A., & Ho, C. S. H. (2022) · Journal of Medical Internet Research · doi:10.2196/39527 · Cited by 21 · see citing works
- Authors
- Jappe, L. M., Frank, G. K. W., Shott, M. E., Rollin, M. D. H., Pryor, T., Hagman, J. O., Yang, T. T., & Davis, E.
- Affiliations
- University of Colorado Denver (US)
- University of California San Diego (US)
- Corresponding author
- Frank, Guido K.W.
- Venue
- International Journal of Eating Disorders
- Publisher
- Wiley
- Published
- 2011-04-06
- Volume
- 44
- Issue
- 4
- Pages
- 317-324
- ISSN
- 0276-3478 (ISSN-L)
- 1098-108X
- PMC
- PMC3072848
- OpenAlex
- W2156148482
- Cited by
- 119
- References
- 33
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 10 · 2023: 13 · 2022: 5 · 2021: 14 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 10 · 2016: 7 · 2015: 11 · 2014: 12 · 2013: 7 · 2012: 5
- FWCI
- 5.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- International Journal of Eating Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH085734, K23MH080135)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- anorexia nervosa, punishment sensitivity, reward sensitivity, reward processing, punishment processing, self-control, harm avoidance, anxiety, female patients, trait markers, eating disorders
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Anorexia Nervosa, Child, Female, Humans, Middle Aged, Personality, Personality Inventory, Punishment, Surveys and Questionnaires, Reward, Self Concept
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
