Feasibility of conducting a randomized clinical trial using family-based treatment for avoidant/restrictive food intake disorder
Abstract
Treatments for avoidant/restrictive food intake disorder (ARFID) lack strong empirical support. There is a critical need to conduct adequately powered studies to identify effective treatments for ARFID. As a first step, the primary aim of this study was to assess the feasibility of conducting a randomized clinical trial (RCT) comparing Family-based Treatment for ARFID (FBT-ARFID) to usual care (UC). The primary outcomes were recruitment, attrition, suitability, and expectancy rates. The secondary aim was to assess changes in percent estimated body weight, eating related psychopathology, and parental self-efficacy from baseline to end of treatment/UC period in both groups. Recruitment rates were 1.87 per month; 28 children with ARFID and their families were randomized and attrition rate was 21%. Therapeutic suitability and expectancy rating suggested that FBT-ARFID was acceptable to families. Effect size (ES) differences on measures of weight and clinical severity were moderate to large, favoring FBT-ARFID over UC. Parental self-efficacy improvement also demonstrated a large ES favoring FBT-ARFID, which was correlated with improvements in ARFID symptoms. There is a research gap between our knowledge base on how to treat children with ARFID and clinical need. The data presented suggest that an RCT comparing FBT-ARFID and UC is feasible to conduct.
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There are promising psychosocial treatments for ARFID in children and adolescents.
“There are currently a number of promising psychosocial treatments for ARFID in children and adolescents (e.g., Dumont, Jansen, Kroes, de Haan, & Mulkens, 2019); Lock, Sadeh-Sharvit, & L’Insalata, 2019; Sharp et al., 2016; Thomas et al., in press).”
From Cognitive-behavioral therapy for adults with avoidant/restrictive food intake disorder (2021) · cites this paper as Lock et al., 2019
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Eating Disorders: Evaluation and Management
Kim, Y. R., Murray, H. B., Thomas, J. J., & Eddy, K. T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-11844-9.00035-7
Eating Disorders: Updates and Innovations
(2024) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.24022009
Carletti, L., Porte, C., Helbert, S., Hooreman, M., Charpentier, F., Delorme, R., Elandaloussi, Y., Stordeur, C., & Ayrolles, A. (2024) · Research Square · doi:10.21203/rs.3.rs-4719121/v1
Self-Efficacy and Accommodation Behaviors in Caregivers of Youths With Eating Disorders
Radovic, L. K., Suen, J., Marshall, S. K., Lam, P., Geller, J., & Coelho, J. S. (2024) · Clinical Practice in Pediatric Psychology · doi:10.1037/cpp0000538
Avoidant Restrictive Food Intake Disorder: A Case Series
Chikkala, S. M., Russell, P. S. S., Basker, M. M., Joseph, R. G., Bavishna, S., Sebastian, S., & Reshmi, Y. S. (2024) · Current Medical Issues · doi:10.4103/cmi.cmi_74_24
Avoidant/Restrictive Food Intake Disorder: Comorbidities and Longitudinal Course
Kambanis, P. E., Rozzell‐Voss, K. N., Lawson, E. A., Thomas, J. J., & Eddy, K. T. (2024) · Springer eBooks · doi:10.1007/978-3-031-46096-8_91
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Psychological Assessment and Treatment
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Family-Based Treatment for Avoidant/Restrictive Food Intake Disorder: Last-Session Reflections
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- Authors
- Lock, J., Sadeh‐Sharvit, S., & L'Insalata, A.
- Affiliations
- Stanford University (US)
- Stanford Medicine (US)
- Department of Psychiatry and Behavioral Sciences Stanford University Stanford California
- Corresponding author
- Lock, James
- Venue
- International Journal of Eating Disorders
- Publisher
- Wiley
- Published
- 2019-03-29
- Volume
- 52
- Issue
- 6
- Pages
- 746-751
- ISSN
- 0276-3478 (ISSN-L)
- 1098-108X
- OpenAlex
- W2928472045
- Cited by
- 94
- References
- 28
- Citations by year
- 2026: 15 · 2025: 14 · 2024: 19 · 2023: 21 · 2022: 8 · 2021: 8 · 2020: 7 · 2019: 2
- FWCI
- 7.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Eating Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- avoidant/restrictive food intake disorder, family-based treatment, trial feasibility, usual care comparison, body weight, parental self-efficacy, children, eating disorders
- MeSH terms
- Feeding and Eating Disorders, Child, Feasibility Studies, Female, Humans, Male, Psychopathology, Retrospective Studies, Treatment Outcome
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