The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Proteome and proteomics: New technologies, new concepts, and new words
Abstract
The goal of proteomics is a comprehensive, quantitative description of protein expression and its changes under the influence of biological perturbations such as disease or drug treatment. Quantitative analysis of protein expression data obtained by high‐throughput methods has led us to define the concept of “regulatory homology” and use it to begin to elucidate the basic structure of gene expression control in vivo. Such investigations lay the groundwork for construction of comprehensive databases of mechanisms (cataloguing possible biological outcomes), the next logical step after the soon to be completed cataloguing of genes and gene products. Mechanism databases provide a roadmap towards effective therapeutic intervention that is more direct than that offered by conventional genomics approaches.
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Cites
Bilheimer, D. W., Grundy, S. M., Brown, M. S., & Goldstein, J. L. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.13.4124 · Cited by 557
Cited by
Mass spectrometry–based proteomics turns quantitative
Ong, S.-E., & Mann, M. (2005) · Nature Chemical Biology · doi:10.1038/nchembio736 · Cited by 1,572
Templin, M. F., Stoll, D., Schrenk, M., Traub, P. C., Vöhringer, C. F., & Joos, T. O. (2002) · Trends in Biotechnology · doi:10.1016/s0167-7799(01)01910-2 · Cited by 572
Proteomics: new perspectives, new biomedical opportunities
Banks, R. E., Dunn, M. J., Hochstrasser, D. F., Sanchez, J.-C., Blackstock, W., Pappin, D. J., & Selby, P. J. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03214-1 · Cited by 451
Gorrochategui, E., Jaumot, J., Lacorte, S., & Tauler, R. (2016) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2016.07.004 · Cited by 352
Wernersson, A.-S., Carere, M., Maggi, C., Tusil, P., Soldan, P., James, A., Sanchez, W., Dulio, V., Broeg, K., Reifferscheid, G., et al. (2015) · Environmental Sciences Europe · doi:10.1186/s12302-015-0039-4 · Cited by 353
Metadata
- Authors
- Anderson, N. L., & Anderson, N. G.
- Venue
- ELECTROPHORESIS
- Publisher
- Wiley
- Published
- 1998-08
- Volume
- 19
- Issue
- 11
- Pages
- 1853-1861
- ISSN
- 0173-0835 (ISSN-L)
- 1522-2683
- OpenAlex
- W2121418514
- Cited by
- 1,055
- References
- 1
- FWCI
- 26.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Anderson, N. L., & Anderson, N. G. (1998). Proteome and proteomics: New technologies, new concepts, and new words. ELECTROPHORESIS. https://doi.org/10.1002/elps.1150191103
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
