The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Biomaterials and nanomedicine for bone regeneration: Progress and future prospects
Open accessAbstract
Bone defects pose a heavy burden on patients, orthopedic surgeons, and public health resources. Various pathological conditions cause bone defects including trauma, tumors, inflammation, osteoporosis, and so forth. Auto‐ and allograft transplantation have been developed as the most commonly used clinic treatment methods, among which autologous bone grafts are the golden standard. Yet the repair of bone defects, especially large‐volume defects in the geriatric population or those complicated with systemic disease, is still a challenge for regenerative medicine from the clinical perspective. The fast development of biomaterials and nanomedicine favors the emergence and promotion of efficient bone regeneration therapies. In this review, we briefly summarize the progress of novel biomaterial and nanomedical approaches to bone regeneration and then discuss the current challenges that still hinder their clinical applications in treating bone defects.
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Cites
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
Johnell, O., & Kanis, J. A. (2006) · Osteoporosis International · doi:10.1007/s00198-006-0172-4 · Cited by 4,704
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
Kusumbe, A. P., Ramasamy, S. K., & Adams, R. H. (2014) · Nature · doi:10.1038/nature13145 · Cited by 2,155
Dimensional ridge alterations following tooth extraction. An experimental study in the dog
Araújo, M. G., & Lindhe, J. (2005) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.2005.00642.x · Cited by 1,954
Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012
Eke, P. I., Dye, B. A., Wei, L., Slade, G. D., Thornton‐Evans, G. O., Borgnakke, W. S., Taylor, G. W., Page, R. C., Beck, J. D., & Genco, R. J. (2015) · Journal of Periodontology · doi:10.1902/jop.2015.140520 · Cited by 1,481
Long-Term Risk of Osteoporotic Fracture in Malmö
Kanis, J. A., Johnell, O., Oden, A., Sernbo, I., Redlund-Johnell, I., Dawson, A., De Laet, C., & Jonsson, B. (2000) · Osteoporosis International · doi:10.1007/s001980070064 · Cited by 1,027
Ho-Shui-Ling, A., Bolander, J., Rustom, L. E., Johnson, A. W., Luyten, F. P., & Picart, C. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.07.017 · Cited by 961
Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics
Tao, W., Zhu, X., Yu, X., Zeng, X., Xiao, Q., Zhang, X., Ji, X., Wang, X., Shi, J., Zhang, H., et al. (2017) · Advanced Materials · doi:10.1002/adma.201603276 · Cited by 883
Self-citationInflammatory bone loss: pathogenesis and therapeutic intervention
Redlich, K., & Smolen, J. S. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3669 · Cited by 830
Baldwin, P., Li, D. J., Auston, D. A., Mir, H. S., Yoon, R. S., & Koval, K. J. (2019) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0000000000001420 · Cited by 773
Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications
Tao, W., Kong, N., Ji, X., Zhang, Y., Sharma, A., Ouyang, J., Qi, B., Wang, J., Xie, N., Kang, C., et al. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00823j · Cited by 615
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Afzal, O., Altamimi, A. S. A., Nadeem, M. S., Alzarea, S. I., Almalki, W. H., Tariq, A., Mubeen, B., Murtaza, B. N., Iftikhar, S., Riaz, N., et al. (2022) · Nanomaterials · doi:10.3390/nano12244494 · Cited by 468
Controlling the biodistribution and clearance of nanomedicines
Cabral, H., Li, J., Miyata, K., & Kataoka, K. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00138-1 · Cited by 303
Novel approaches and biomaterials for bone tissue engineering: a focus on silk fibroin
Paladini, F., & Pollini, M. (2022) · Materials · doi:10.3390/ma15196952 · Cited by 51
Engineered stem cells by emerging biomedical stratagems
Wang, J., Zhang, X., Chen, H., Ren, H., Zhou, M., & Zhao, Y. (2024) · Science Bulletin · doi:10.1016/j.scib.2023.12.006 · Cited by 37
Self-citationMarszalik, K., Polak, M., Berniak, K., Knapczyk-Korczak, J., Szewczyk, P. K., Marzec, M. M., & Stachewicz, U. (2026) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01568 · Cited by 4
Metadata
- Authors
- Zhou, J., Zhang, Z., Joseph, J., Zhang, X., Ferdows, B. E., Patel, D. N., Chen, W., Banfi, G., Molinaro, R., Cosco, D., Kong, N., Joshi, N., Farokhzad, O. C., Corbo, C., & Tao, W.
- Venue
- Exploration
- Publisher
- Wiley
- Published
- 2021-10
- Volume
- 1
- Issue
- 2
- Pages
- 20210011-20210011
- ISSN
- 2766-2098 (ISSN-L)
- OpenAlex
- W3208265643
- Cited by
- 253
- References
- 62
- FWCI
- 12.95
- Type
- journal article
- Language
- en
- Open access
- gold
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- Zhou, J., Zhang, Z., Joseph, J., Zhang, X., Ferdows, B. E., Patel, D. N., Chen, W., Banfi, G., Molinaro, R., Cosco, D., Kong, N., Joshi, N., Farokhzad, O. C., Corbo, C., & Tao, W. (2021). Biomaterials and nanomedicine for bone regeneration: Progress and future prospects. Exploration. https://doi.org/10.1002/exp.20210011
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