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Statins: Do They Aggravate or Ameliorate Neuropathic Pain?

Bhalla, S., Singh, N., & Jaggi, A. S. (2014) · Journal of Pain · doi:10.1016/j.jpain.2014.06.012 · Cited by 25

The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping

Maghe, C., Trillet, K., André‐Grégoire, G., Kerhervé, M., Merlet, L., Jacobs, K., Schauer, K., Bidère, N., & Gavard, J. (2024) · Cell Reports · doi:10.1016/j.celrep.2023.113631 · Cited by 23

Atorvastatin preconditioning attenuates the production of endothelin-1 and prevents experimental vasospasm in rats

Chang, C.-Z., Wu, S., Lin, C.-L., Hwang, S., Howng, S., & Kwan, A. (2010) · Acta Neurochirurgica · doi:10.1007/s00701-010-0652-3 · Cited by 23

Low Endogenous and Chemical Induced Heat Shock Protein Induction in a 0N3Rtau-Expressing Drosophila Larval Model of Alzheimer's Disease

Sinadinos, C., Quraishe, S., Sealey, M. A., Samson, P. B., Mudher, A. K., & Wyttenbach, A. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-121534 · Cited by 23

Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism

Barros, S., Coimbra, A. M., Alves, N., Pinheiro, M., Quintana, J. B., Santos, M. M., & Neuparth, T. (2020) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2020.1733722 · Cited by 23

The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats

Sun, J., Chuncheng, X., Liu, W., Lu, D., Qiao, W., Huang, Q., Huo, Z., Shen, H., & Lin, Z. (2012) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2012.1076 · Cited by 23

Statins decrease chondroitin sulfate proteoglycan expression and acute astrocyte activation in central nervous system injury

Holmberg, E. G., Zhang, S.-X., Sarmiere, P. D., Kluge, B., White, J. T., & Doolen, S. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.07.020 · Cited by 21

The Benefits Outweigh the Risks of Treating Hypercholesterolemia: The Statin Dilemma

Hussain, A., Kaler, J., & Ray, S. D. (2023) · Cureus · doi:10.7759/cureus.33648 · Cited by 20

The Mevalonate Pathway in Alzheimer’s Disease — Cholesterol and Non-Sterol Isoprenoids

Mohamed, A., Smith, K. T., & Chaves, E. (2015) · InTech eBooks · doi:10.5772/59904 · Cited by 17

Fluvastatin protects neuronal cells from hydrogen peroxide-induced toxicity with decreasing oxidative damage and increasing PI3K/Akt/mTOR signalling

Wang, M., Wang, J., Liu, M., & Chen, G. (2021) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgaa058 · Cited by 16

Non-traditional Dosing of Statins in Statin-Intolerant Patients—Is It Worth a Try?

Cornier, M., & Eckel, R. H. (2014) · Current Atherosclerosis Reports · doi:10.1007/s11883-014-0475-4 · Cited by 14

Molecular mechanisms of toxicity of simvastatin, widely used cholesterol-lowering drug. A review

Kaminsky, Y. G., & Kosenko, E. A. (2009) · Open Medicine · doi:10.2478/s11536-009-0123-5 · Cited by 12

Association of Long-Term Atorvastatin with Escalated Stroke-Induced Neuroinflammation in Rats

Simani, L., Naderi, N., Khodagholi, F., Mehrpour, M., & Nasoohi, S. (2016) · Journal of Molecular Neuroscience · doi:10.1007/s12031-016-0814-8 · Cited by 10

Evaluation of statins impacts on cognitive function among diabetic patients

Hammad, M. A., Sulaiman, S. A. S., Aziz, N. A., & Noor, D. A. M. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.04.006 · Cited by 9

Statin use and cognitive function in middle-aged adults with type 1 diabetes

Nunley, K. A., Orchard, T. J., Ryan, C. M., Miller, R. G., Costacou, T., & Rosano, C. (2017) · World Journal of Diabetes · doi:10.4239/wjd.v8.i6.286 · Cited by 5

Differential Roles of the Mevalonate Pathway in the Development and Survival of Mouse Purkinje Cells in Culture

Barszczyk, A., Sun, H., Quan, Y., Zheng, W., Charlton, M. P., & Feng, Z. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8778-6 · Cited by 5

Preliminary Study on Clusterin Protein (sCLU) Expression in PC-12 Cells Overexpressing Wild-Type and Mutated (Swedish) AβPP genes Affected by Non-Steroid Isoprenoids and Water-Soluble Cholesterol

Pająk, B., Kania, E., Gołaszewska, A., & Orzechowski, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20061481 · Cited by 5

Statin Use, Ageing, and Cognition: A Review

Stephenson, N. E., & Crowe, S. F. (2016) · Australian Psychologist · doi:10.1111/ap.12116 · Cited by 4

REVERSIBLE NEUROTROPHIC KERATOPATHY ASSOCIATED WITH ROSUVASTATIN THERAPY: A CASE REPORT

Elnahry, A. G., & Elnahry, G. A. (2019) · Journal of Population Therapeutics and Clinical Pharmacology · doi:10.15586/jptcp.v26i2.627 · Cited by 3

Lactacystin Stimulates Stellation of Cultured Rat Cortical Astrocytes

Ren, Q., Yu, Y., Pan, D., Luo, X., Wang, X., & Wang, W. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9830-6 · Cited by 3

Blood cholesterol and mitochondrial toxicity of simvastatin

Kaminsky, Y. G., & Kosenko, E. A. (2011) · Biology Bulletin Reviews · doi:10.1134/s2079086411040013 · Cited by 2

Rosuvastatin Induces Delayed Preconditioning Against Oxygen-glucose Deprivation In Cultured Cortical Neurons

David, B. (2009) · Frontiers in Systems Neuroscience · doi:10.3389/conf.neuro.01.2009.04.148 · Cited by 1

Combined Treatment with Hydrophilic and Lipophilic Statins Improves Neurological Outcomes Following Experimental Cardiac Arrest in Mice

Nakayama, S., Taguchi, N., Isaka, Y., Nakamura, T. K., & Tanaka, M. (2019) · Neurocritical Care · doi:10.1007/s12028-019-00862-w · Cited by 1

The Effect of Statins on the Differentiation and Function of Central Nervous System Cells

Chamani, S., Mobasheri, L., Zerehpoosh, S., Naghizadeh, A., McCloskey, A. P., Rizzo, M., Jamialahmadi, T., & Sahebkar, A. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230308121645 · Cited by 1

Cholesterol Disturbances in Inherited Neurodegenerative Diseases : Studies on Npc1, Ppt1 and Ctsd deficient mice

Mutka, A. (2009) · Työväentutkimus Vuosikirja

Cholesterol Disturbances in Inherited Neurodegenerative Diseases

Mutka, A. (2009)

Combined Pharmacotherapy for the Treatment of Traumatic Brain Injury Rehabilitation and Recovery of Function Following Prefrontal Cortex Controlled Cortical Impact in Rats

Kyser, A. N. (2009) · EngagedScholarship @ Cleveland State University (Cleveland State University)

The effects of long-term atorvastatin use on the cytoarchitecture of new and older neurons of sensorimotor nucleus HVC in a juvenile songbird modelPreprint

Tsoi, S. C., Barrientos, A. C., Pytte, C. L., Vicario, D. S., & Phan, M. L. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/196204

Statins and Protein Prenylation in the Retina

Ling, J. Y. M. (2017) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r39s1m03v

Degeneration of pyramidal cells of CA1, CA2, and CA3 are of the hippocampus in male rats under the influence of simvastatinPreprint

Ranaiy, M. S., Farokhi, F., & Babaei-Balderlou, F. (2021) · Research Square · doi:10.21203/rs.3.rs-882972/v1

Degeneration of pyramidal cells of CA1, CA2, and CA3 area of the hippocampus in male rats under the influence of SimvastatinPreprint

Ranaiy, M. S., Farokhi, F., & Babaei-Balderlou, F. (2021) · Research Square · doi:10.21203/rs.3.rs-898243/v1

Effect of Intracerebroventricular Injection (ICV) of Simvastatin on Cerebellum and CA1 Region of the Hippocampus

Farokhi, F. (2022) · Neurology & Neurotherapy Open Access Journal · doi:10.23880/nnoaj-16000165

Daily high doses of atorvastatin alter neuronal morphology in a juvenile songbird model

Tsoi, S. C., Barrientos, A. C., Vicario, D. S., Phan, M. L., & Pytte, C. L. (2025) · PLoS ONE · doi:10.1371/journal.pone.0314690

Role of mevalonate pathway in the central nervous system

Pallottini, V. (2017) · theses.fr (ABES) · doi:10.70675/0b915c38ze7faz4fabz9062z79d24e166f77

Elucidating the Vulnerability of Glioblastoma Stem-like Cells to Lysosomal Dysfunctions

Maghe, C. (2023) · theses.fr (ABES) · doi:10.70675/cb5da8bdzc225z4cf1z80a7zeb24afa442f9

Statin-Induced Mitochondrial Coenzyme Q Deficiency Alters Mitochondrial Redox Homeostasis and Bioenergetic Function in AstrocytesPreprint

Wojcicki, K., Gałgański, Ł., Budzinska, A., Figura, G., Pijanowski, W., & Jarmuszkiewicz, W. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.10.731318

Biphasic effects of statins on neuron cell functions under oxygen–glucose deprivation and normal culturing conditions via different mechanisms

Wang, H., Chen, Y., Li, P., Chen, Y., Yu, D., Tan, Q., Liu, X., & Guo, Z. (2022) · Pharmacology Research & Perspectives · doi:10.1002/prp2.1001 · Cited by 7

Strategies for Integrating Technology as a Team Member

Mani, N. S., Ottosen, T., Wright, S. T., McCall, R. C., Conklin, J., & Adapa, K. (2018) · North Carolina Medical Journal · doi:10.18043/ncm.79.4.245 · Cited by 2

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Protect Cortical Neurons from Excitotoxicity

Zacco, A., Togo, J. A., Spence, K., Ellis, A., Lloyd, D., Furlong, S., & Piser, T. M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-35-11104.2003 · Cited by 255

Differences in statin associated neuroprotection corresponds with either decreased production of IL-1β or TNF-α in an in vitro model of neuroinflammation-induced neurodegeneration

McFarland, A. J., Davey, A. K., McDermott, C., Grant, G. D., Lewohl, J. M., & Anoopkumar‐Dukie, S. (2018) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2018.03.005 · Cited by 42

Simvastatin Results in a Dose-Dependent Toxic Effect on Spiral Ganglion Neurons in anIn VitroOrganotypic Culture Assay

Leitmeyer, K., Glutz, A., Setz, C., Wieland, L., Egloff, S., Bodmer, D., & Brand, Y. (2016) · BioMed Research International · doi:10.1155/2016/3580359 · Cited by 7