Cited by 1,374Chromosomal and Genetic VariationsEvolution and Genetic DynamicsGenomics and Phylogenetic Studies

The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.

Origin and evolution of retroelements based upon their reverse transcriptase sequences

Open access

Xiong, Y., Eickbush, T. H.·1990·The EMBO Journal

DOI 10.1002/j.1460-2075.1990.tb07536.xPMC PMC552073

Open this paper in CoChat — free account

Abstract

To study the evolutionary relationship of reverse transcriptase (RT) containing genetic elements, a phylogenetic tree of 82 retroelements from animals, plants, protozoans and bacteria was constructed. The tree was based on seven amino acid domains totalling 178 residues identified in all RTs. We have also identified these seven domains in the RNA-directed RNA polymerases from various plus-strand RNA viruses. The sequence similarity of these RNA polymerases to RT suggests that these two enzymes evolved from a common ancestor, and thus RNA polymerase can be used as an outgroup to root the RT tree. A comparison of the genetic organization of the various RT containing elements and their position on the tree allows several inferences concerning the origin and evolution of these elements. The most probable ancestor of current retroelements was a retrotransposable element with both gag-like and pol-like genes. On one major branch of the tree, organelle and bacterial sequences (e.g. group II introns and bacterial msDNA) appear to have captured the RT sequences from retrotransposons which lack long terminal repeats (LTRs). On the other major branch, acquisition of LTRs gave rise to two distinct groups of LTR retrotransposons and three groups of viruses: retroviruses, hepadnaviruses and caulimoviruses.

Integrity signals

Registry

Crossref · 10.1002/j.1460-2075.1990.tb07536.x

Cites

78 of 78 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Saitou, N., & Nei, M. (1987) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040454 · Cited by 59,959
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus
TEMIN, H. M., & MIZUTANI, S. (1970) · Nature · doi:10.1038/2261211a0 · Cited by 2,128
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
BALTIMORE, D. (1970) · Nature · doi:10.1038/2261209a0 · Cited by 2,068
Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
Feng, D.-F., & Doolittle, R. F. (1987) · Journal of Molecular Evolution · doi:10.1007/bf02603120 · Cited by 1,883
Identification of four conserved motifs among the RNA‐dependent polymerase encoding elements.
Poch, O., Sauvaget, I., Delarue, M. H., & Tordo, N. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08565.x · Cited by 1,202
NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION
Weiner, A. M., Deininger, P. L., & Efstratiadis, A. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.003215 · Cited by 1,019
Molecular Evolutionary Genetics
Wallace, B. B. (1988) · Journal of Heredity · doi:10.1093/oxfordjournals.jhered.a110475 · Cited by 964
Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses
Kamer, G., & Argos, P. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.18.7269 · Cited by 837
Origins and evolutionary relationships of retroviruses
Doolittle, R. F., Johnson, M. S., & McClure, M. A. (1989) · The Quarterly Review of Biology · doi:10.1086/416128 · Cited by 577
The Origin and Evolution of Retroposons
ROGERS, J. H. (1985) · International review of cytology · doi:10.1016/s0074-7696(08)61375-3 · Cited by 548

Show all 77 references

Sorted by citations

Items 201–300 of 1,000

Establishment and Characterization of Molecular Clones of Porcine Endogenous Retroviruses Replicating on Human Cells
Czauderna, F., Fischer, N., Böller, K., Kurth, R., & Tönjes, R. R. (2000) · Journal of Virology · doi:10.1128/jvi.74.9.4028-4038.2000 · Cited by 109
A diversity of uncharacterized reverse transcriptases in bacteria
Simon, D. M., & Zimmerly, S. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn867 · Cited by 111
Genes of the Pseudoviridae (Ty1/copia Retrotransposons)
Peterson-Burch, B. D., & Voytas, D. F. (2002) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a004008 · Cited by 107
Sequence determination of the Crimean–Congo hemorrhagic fever virus L segment
Kinsella, E., Martin, S. G., Grolla, A., Czub, M., Feldmann, H., & Flick, R. (2004) · Virology · doi:10.1016/j.virol.2003.09.046 · Cited by 108
C-Terminal Regions of the Human Telomerase Catalytic Subunit Essential for In Vivo Enzyme Activity
Banik, S. S. R., Guo, C., Smith, A. C., Margolis, S. S., Richardson, D. A., Tirado, C. A., & Counter, C. M. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.17.6234-6246.2002 · Cited by 108
Autonomous transposition of the tobacco retrotransposon Tto1 in rice.
Hirochika, H., Otsuki, H., Yoshikawa, M., Otsuki, Y., Sugimoto, K., & Takeda, S. (1996) · The Plant Cell · doi:10.1105/tpc.8.4.725 · Cited by 108
Nimble and Ready to Mingle: Transposon Outbursts of Early Development
Rodriguez‐Terrones, D., & Torres‐Padilla, M. (2018) · Trends in Genetics · doi:10.1016/j.tig.2018.06.006 · Cited by 106
Reverse transcription of retroviruses and LTR retrotransposons
Wilhelm, M. L., & Wilhelm, F. X. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000937 · Cited by 107
Genomic Evolution of the Long Terminal Repeat Retrotransposons in Hemiascomycetous YeastsPreprint
Neuvéglise, C., Feldmann, H., Bon, E., Gaillardin, C. M., & Casarégola, S. (2002) · Genome Research · doi:10.1101/gr.219202 · Cited by 106
Structure, Divergence, and Distribution of the CRR Centromeric Retrotransposon Family in Rice
Nagaki, K. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msi069 · Cited by 105
Mutually Exclusive Distribution of IS 1548 and GBSi1, an Active Group II Intron Identified in Human Isolates of Group B Streptococci
Granlund, M., Michel, F., & Norgren, M. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.8.2560-2569.2001 · Cited by 105
The contribution of transposable elements to size variations between four teleost genomes
Gao, B., Shen, D., Xue, S., Chen, C., Cui, H., & Song, C. (2016) · Mobile DNA · doi:10.1186/s13100-016-0059-7 · Cited by 100
Retrons and their applications in genome engineering
Simon, A. J., Ellington, A. D., & Finkelstein, I. J. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz865 · Cited by 104
Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases
Menéndez‐Arias, L. (2002) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(02)71042-8 · Cited by 102
Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity
Seleme, M. D. C., Vetter, M. R., Cordaux, R., Bastone, L. A., Batzer, M. A., & Kazazian, H. H. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601324103 · Cited by 104
Ty3/Gypsy Retrotransposons: Description of New Arabidopsis thaliana Elements and Evolutionary Perspectives Derived from Comparative Genomic Data
Marı́n, I., & Lloréns, C. (2000) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026385 · Cited by 104
Resistance of Hepatitis B Virus to Antiviral Drugs: Current Aspects and Directions for Future Investigation
Delaney, W. E., LOCARNINI, S. A., & Shaw, T. (2001) · Antiviral chemistry & chemotherapy · doi:10.1177/095632020101200101 · Cited by 103
Retrotransposons of rice: their regulation and use for genome analysis
Hirochika, H. (1997) · Plant Molecular Biology · doi:10.1023/a:1005774705893 · Cited by 103
An indicator gene for detection of germline retrotransposition in transgenic Drosophila demonstrates RNA‐mediated transposition of the LINE I element.
Jensen, S., & Heidmann, T. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07719.x · Cited by 103
The Proteins and Functions of Plant Pararetroviruses: Knowns and Unknowns
Höhn, T., Fütterer, J., & Hull, R. (1997) · Critical Reviews in Plant Sciences · doi:10.1080/07352689709701947 · Cited by 102
Synchronous Expression of LINE-1 RNA and Protein in Mouse Embryonal Carcinoma Cells
Martin, S. L., & Branciforte, D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.9.5383 · Cited by 102
The mauriceville plasmid reverse transcriptase can initiate cDNA synthesis de novo and may be related to reverse transcriptase and DNA polymerase progenitor
Wang, H., & Lambowitz, A. M. (1993) · Cell · doi:10.1016/0092-8674(93)90317-j · Cited by 102
Genomic Analysis of Caenorhabditis elegans Reveals Ancient Families of Retroviral-like Elements
Bowen, N. J., & McDonald, J. F. (1999) · Genome Research · doi:10.1101/gr.9.10.924 · Cited by 102
Involvement of Ethylene in Stress-Induced Expression of the TLC1.1 Retrotransposon from Lycopersicon chilense Dun.
Tapia, G., Verdugo, I., Yáñez, M., Ahumada, I., Theoduloz, C., Cordero, C., Poblete, F., González-Pérez, E., & Ruíz-Lara, S. (2005) · PLANT PHYSIOLOGY · doi:10.1104/pp.105.059766 · Cited by 101
The sunflower (Helianthus annuus L.) genome reflects a recent history of biased accumulation of transposable elements
Staton, S. E., Bakken, B. H., Blackman, B. K., Chapman, M. A., Kane, N. C., Tang, S., Ungerer, M. C., Knapp, S. J., Rieseberg, L. H., & Burke, J. M. (2012) · The Plant Journal · doi:10.1111/j.1365-313x.2012.05072.x · Cited by 101
Petunia Vein-Clearing Virus: A Plant Pararetrovirus with the Core Sequences for an Integrase Function
Richert‐Pöggeler, K. R., & Shepherd, R. J. (1997) · Virology · doi:10.1006/viro.1997.8712 · Cited by 101
Transient Selection of A Hepatitis B Virus Polymerase Gene Mutant Associated With A Decreased Replication Capacity and Famciclovir Resistance
Pichoud, C., Seignères, B., Wang, Z., TREPO, C. G., & Zoulim, F. (1999) · Hepatology · doi:10.1002/hep.510290119 · Cited by 101
Mammalian LINE‐1 Retrotransposons and Related Elements
Moran, J. V., & Gilbert, N. (2007) · Wiley eBooks · doi:10.1128/9781555817954.ch35 · Cited by 103
Penelope-like elements – a new class of retroelements: distribution, function and possible evolutionary significance
Evgen’ev, M. B., & Arkhipova, I. R. (2005) · Cytogenetic and Genome Research · doi:10.1159/000084984 · Cited by 99
OARE-1, a Ty1-copia Retrotransposon in Oat Activated by Abiotic and Biotic Stresses
Kimura, Y., Tosa, Y., Shimada, S., Sogo, R., Kusaba, M., Sunaga, T., Betsuyaku, S., Eto, Y., Nakayashiki, H., & MAYAMA, S. (2001) · Plant and Cell Physiology · doi:10.1093/pcp/pce171 · Cited by 100
Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon
Takahara, T. (1996) · Human Molecular Genetics · doi:10.1093/hmg/5.7.989 · Cited by 102
Retroviruses in plants?
Peterson-Burch, B. D., Wright, D. A., Laten, H. M., & Voytas, D. F. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)01981-8 · Cited by 100
Envelope -Class Retrovirus-Like Elements Are Widespread, Transcribed and Spliced, and Insertionally Polymorphic in PlantsPreprint
Vicient, C. M., Kalendar, R. N., & Schulman, A. H. (2001) · Genome Research · doi:10.1101/gr.193301 · Cited by 100
Occurrence of a LINE sequence in the 3′ UTR of the goat αs1-casein E-encoding allele associated with reduced protein synthesis level
Pérez, M. J., Leroux, C., Sánchez, A., & Martin, P. (1994) · Gene · doi:10.1016/0378-1119(94)90063-9 · Cited by 99
Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention
Jones, S. A., & Hu, J. (2013) · Emerging Microbes & Infections · doi:10.1038/emi.2013.56 · Cited by 98
Retroelements, transposons and methylation status in the genome of oil palm (Elaeis guineensis) and the relationship to somaclonal variation
Kubis, S. E., Castilho, A., Vershinin, A. V., & Heslop-Harrison, J. S. (2003) · Plant Molecular Biology · doi:10.1023/a:1023942309092 · Cited by 99
Non-LTR Retrotransposons Encoding a Restriction Enzyme-Like Endonuclease in Vertebrates
Volff, J., Körting, C., Froschauer, A., Sweeney, K., & Schartl, M. (2001) · Journal of Molecular Evolution · doi:10.1007/s002390010165 · Cited by 98
Evidence for long‐range oncogene activation by hepadnavirus insertion.
Fourel, G., Couturier, J., Wei, Y., Apiou, F., Tiollais, P., & Buendia, M. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06542.x · Cited by 98
Copia-like retrotransposable element evolution in diploid and polyploid cotton (Gossypium L.)
VanderWiel, P. L., Voytas, D. F., & Wendel, J. F. (1993) · Journal of Molecular Evolution · doi:10.1007/bf02406720 · Cited by 98
Drug therapy for chronic hepatitis B: antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy
Zoulim, F., & TREPO, C. G. (1998) · Journal of Hepatology · doi:10.1016/s0168-8278(98)80191-8 · Cited by 98
An in vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae.
Dombroski, B. A., Feng, Q., Mathias, S. L., Sassaman, D. M., Scott, A. F., Kazazian, H. H., & Boeke, J. D. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.7.4485 · Cited by 97
A new hepadnavirus endemic in arctic ground squirrels in Alaska
Testut, P., Renard, C., Terradillos, O., Vitvitski, L., Tekaia, F., Degott, C., Blake, J., Boyer, B., & Buendia, M. (1996) · Journal of Virology · doi:10.1128/jvi.70.7.4210-4219.1996 · Cited by 100
Comparison of the utility of barley retrotransposon families for genetic analysis by molecular marker techniques
Leigh, F. J., Kalendar, R. N., Lea, V. J., Lee, D., Donini, P., & Schulman, A. H. (2003) · Molecular Genetics and Genomics · doi:10.1007/s00438-003-0850-2 · Cited by 96
Alterations to the Primer Grip of p66 HIV-1 Reverse Transcriptase and Their Consequences for Template-Primer Utilization
Ghosh, M. P., Jacques, P. S., Rodgers, D. W., Ottman, M., Darlix, J., & Grice, S. F. J. L. (1996) · Biochemistry · doi:10.1021/bi952773j · Cited by 96
Retrons, msDNA, and the bacterial genome
Lampson, B. C., Inouye, M., & Inouye, S. (2005) · Cytogenetic and Genome Research · doi:10.1159/000084982 · Cited by 94
An Improved Melon Reference Genome With Single-Molecule Sequencing Uncovers a Recent Burst of Transposable Elements With Potential Impact on Genes
Castanera, R., Ruggieri, V., Pujol, M., García-Más, J., & Casacuberta, J. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2019.01815 · Cited by 94
Bacteria and Archaea Group II introns: additional mobile genetic elements in the environment
Toro, N. (2003) · Environmental Microbiology · doi:10.1046/j.1462-2920.2003.00398.x · Cited by 95
LINEs, SINEs and repetitive DNA: non-LTR retrotransposons in plant genomes
Schmidt, T. (1999) · Plant Molecular Biology · doi:10.1023/a:1006212929794 · Cited by 94
The 3′ ends of tRNA-derived SINEs originated from the 3’ ends of LINEs: A new example from the bovine genome
Okada, N., & Hamada, M. (1997) · Journal of Molecular Evolution · doi:10.1007/pl00000058 · Cited by 93
Is photosynthetic transcriptional regulation in Triticum aestivum L. cv. ‘TugelaDN’ a contributing factor for tolerance to Diuraphis noxia (Homoptera: Aphididae)?
Botha, A., Lacock, L., van Niekerk, C., Matsioloko, M. T., du Preez, F. B., Loots, S., Venter, E., Kunert, K. J., & Cullis, C. A. (2005) · Plant Cell Reports · doi:10.1007/s00299-005-0001-9 · Cited by 92
Long terminal repeat retrotransposons of Mus musculus
McCarthy, E. M., & McDonald, J. F. (2004) · Genome Biology · doi:10.1186/gb-2004-5-3-r14 · Cited by 91
Transfer, Incorporation, and Substitution of Envelope Fusion Proteins among Members of the Baculoviridae , Orthomyxoviridae , and Metaviridae (Insect Retrovirus) Families
Pearson, M. N., & Rohrmann, G. F. (2002) · Journal of Virology · doi:10.1128/jvi.76.11.5301-5304.2002 · Cited by 91
The genomic and physical organization of Ty1-copia-like sequences as a component of large genomes in Pinus elliottii var. elliottii and other gymnosperms.
Kamm, A., Doudrick, R. L., Heslop-Harrison, J. S., & Schmidt, T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.7.2708 · Cited by 91
Transposition of the Retrotransposon MAGGY in Heterologous Species of Filamentous Fungi
Nakayashiki, H., Kiyotomi, K., Tosa, Y., & MAYAMA, S. (1999) · Genetics · doi:10.1093/genetics/153.2.693 · Cited by 91
Alu RNA transcripts in human embryonal carcinoma cells
Sinnett, D., Richer, C., Deragon, J., & Labuda, D. (1992) · Journal of Molecular Biology · doi:10.1016/0022-2836(92)90626-u · Cited by 91
Origin of the retroviruses: when, where, and how?
Hayward, A. (2017) · Current Opinion in Virology · doi:10.1016/j.coviro.2017.06.006 · Cited by 90
The reverse transcriptase of the R2 non-LTR retrotransposon: continuous synthesis of cDNA on non-continuous RNA templates
Bibiłło, A., & Eickbush, T. H. (2002) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.5369 · Cited by 91
Self-citation
Domain structure and three-dimensional model of a group II intron-encoded reverse transcriptase
Blocker, F., Mohr, G., Conlan, L. H., Qi, L., Belfort, M., & Lambowitz, A. M. (2004) · RNA · doi:10.1261/rna.7181105 · Cited by 90
RNA‐mediated transposition of the tobacco retrotransposon Tnt1 in Arabidopsis thaliana.
Lucas, H., Feuerbach, F., Kunert, K. J., Grandbastien, M., & Caboche, M. M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07231.x · Cited by 90
Horizontal transfer
KIDWELL, M. G. (1992) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(05)80109-1 · Cited by 90
DNA methylation dynamics at transposable elements in mammals
Jansz, N. (2019) · Essays in Biochemistry · doi:10.1042/ebc20190039 · Cited by 95
Chicken repeat 1 elements contain a pol-like open reading frame and belong to the non-long terminal repeat class of retrotransposons.
Burch, J. B., Davis, D. L., & Haas, N. B. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.8199 · Cited by 89
In vitro enzymatic activity of human immunodeficiency virus type 1 reverse transcriptase mutants in the highly conserved YMDD amino acid motif correlates with the infectious potential of the proviral genome
Wakefield, J., Jablonski, S. A., & Morrow, C. D. (1992) · Journal of Virology · doi:10.1128/jvi.66.11.6806-6812.1992 · Cited by 89
Natural selection on gene function drives the evolution of LTR retrotransposon families in the rice genomePreprint
Baucom, R. S., Estill, J. C., Leebens‐Mack, J., & Bennetzen, J. L. (2008) · Genome Research · doi:10.1101/gr.083360.108 · Cited by 89
Characterization of the Uukuniemi Virus Group (Phlebovirus: Bunyaviridae): Evidence for Seven Distinct Species
Palacios, G. F., Savji, N., da Rosa, A. T., Guzmán, H., Yu, X., Desai, A., Rosen, G. E., Hutchison, S. K., Lipkin, W. I., & Tesh, R. B. (2013) · Journal of Virology · doi:10.1128/jvi.02719-12 · Cited by 88
An ultraprocessive, accurate reverse transcriptase encoded by a metazoan group II intron
Zhao, C., Liu, F., & Pyle, A. M. (2017) · RNA · doi:10.1261/rna.063479.117 · Cited by 89
Duck Hepatitis B Virus: An Invaluable Model System for HBV Infection
Schultz, U., Grgacic, E. V. L., & Nassal, M. (2004) · Advances in virus research · doi:10.1016/s0065-3527(04)63001-6 · Cited by 88
Evolution and Distribution of Class II-Related Endogenous Retroviruses
Gifford, R. J., Kabát, P., Martin, J. L., Lynch, C., & Tristem, M. (2005) · Journal of Virology · doi:10.1128/jvi.79.10.6478-6486.2005 · Cited by 88
The diversity of Banana streak virus isolates in Uganda
Harper, G., Hart, D. R., Moult, S., Hull, R., Geering, A. D. W., & Thomas, J. E. (2005) · Archives of Virology · doi:10.1007/s00705-005-0610-1 · Cited by 87
Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes
Chen, S., & Li, X. (2007) · BMC Evolutionary Biology · doi:10.1186/1471-2148-7-46 · Cited by 87
Distribution and Phylogeny of Penelope-Like Elements in Eukaryotes
Arkhipova, I. R. (2006) · Systematic Biology · doi:10.1080/10635150601077683 · Cited by 87
A Mutant of Tetrahymena Telomerase Reverse Transcriptase with Increased Processivity
Bryan, T. M., Goodrich, K. J., & Cech, T. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003246200 · Cited by 87
The DIRS1 Group of Retrotransposons
Goodwin, T. J. D., & Poulter, R. T. M. (2001) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a003748 · Cited by 87
Sequence relationship of retrotransposable elements R1 and R2 within and between divergent insect species.
Burke, W. D., Eickbush, D. G., Xiong, Y., Jakubczak, J. L., & Eickbush, T. H. (1993) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a039990 · Cited by 87
Self-citation
A novel exogenous retrovirus sequence identified in humans
Griffiths, D. J., Venables, P. J., Weiss, R. A., & Boyd, M. T. (1997) · Journal of Virology · doi:10.1128/jvi.71.4.2866-2872.1997 · Cited by 87
HRT, a Novel Zinc Finger, Transcriptional Repressor from Barley
Raventós, D., Skriver, K., Schlein, M., Karnahl, K., Rogers, S. W., ROGERS, J. C., & Mundy, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.36.23313 · Cited by 86
Zepp, a LINE‐like retrotransposon accumulated in the Chlorella telomeric region
Higashiyama, T., Noutoshi, Y., Fujie, M., & Yamada, T. (1997) · The EMBO Journal · doi:10.1093/emboj/16.12.3715 · Cited by 86
A novel family of mobile genetic elements is limited to the germline genome in Tetrahymena thermophila
Wuitschick, J. D. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.11.2524 · Cited by 86
NOTES: Ribonucleoprotein Particles with LINE-1 RNA in Mouse Embryonal Carcinoma Cells
Martin, S. L. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.9.4804-4807.1991 · Cited by 86
Interaction of Retroviral Reverse Transcriptase with Template–Primer Duplexes during Replication
Arts, E. J., & Grice, S. F. J. L. (1997) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60041-0 · Cited by 86
Molecular cloning and characterization of AtTERT, a telomerase reverse transcriptase homolog in Arabidopsis thaliana
Oguchi, K., Liu, H., Tamura, K., & Takahashi, H. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01083-2 · Cited by 85
Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase
Singh, K., Marchand, B., Kirby, K. A., Michailidis, E., & Sarafianos, S. G. (2010) · Viruses · doi:10.3390/v2020606 · Cited by 86
Tempo and Mode of Ty Element Evolution in Saccharomyces cerevisiae
Jordan, I. K., & McDonald, J. F. (1999) · Genetics · doi:10.1093/genetics/151.4.1341 · Cited by 84
Retropositional parasitism of SINEs on LINEs: identification of SINEs and LINEs in elasmobranchs
Ogiwara, I., Miya, M. U., Ohshima, K., & Okada, N. (1999) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026214 · Cited by 84
Determination of the entire sequence of turtle CR1: the first open reading frame of the turtle CR1 element encodes a protein with a novel zinc finger motif
Kajikawa, M., Ohshima, K., & Okada, N. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025730 · Cited by 84
Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution
Zhao, C., & Pyle, A. M. (2016) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3224 · Cited by 82
Adaptive Evolution Involving Gene Duplication and Insertion of a Novel Ty1/copia-Like Retrotransposon in Soybean
Kanazawa, A., Liu, B., Kong, F., Arase, S., & Abe, J. (2009) · Journal of Molecular Evolution · doi:10.1007/s00239-009-9262-1 · Cited by 83
Genomic neighborhoods for Arabidopsisretrotransposons: a role for targeted integration in the distribution of the Metaviridae
Peterson-Burch, B. D., Nettleton, D. S., & Voytas, D. F. (2004) · Genome biology · doi:10.1186/gb-2004-5-10-r78 · Cited by 83
Site-specific accumulation of a LINE-like retrotransposon in a sex chromosome of the dioecious plant Cannabis sativa
Sakamoto, K., Ohmido, N., Fukui, K., Kamada, H., & Satoh, S. (2000) · Plant Molecular Biology · doi:10.1023/a:1026574405717 · Cited by 83
Viruses and Evolution – Viruses First? A Personal Perspective
Moelling, K., & Broecker, F. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00523 · Cited by 90
Replication infidelity during a single cycle of Ty1 retrotransposition.
Gabriel, A., Willems, M., Mules, E. H., & Boeke, J. D. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.7767 · Cited by 84
Dasheng: A Recently Amplified Nonautonomous Long Terminal Repeat Element That Is a Major Component of Pericentromeric Regions in Rice
Jiang, N., Bao, Z., Temnykh, S. V., Cheng, Z., Jiang, J., Wing, R. A., McCouch, S. R., & Wessler, S. R. (2002) · Genetics · doi:10.1093/genetics/161.3.1293 · Cited by 82
Nucleotide sequence and protein analysis of a complex piscine retrovirus, walleye dermal sarcoma virus
Holzschu, D. L., Martineau, D., Fodor, S. K., Vogt, V. M., Bowser, P. R., & Casey, J. W. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5320-5331.1995 · Cited by 82
Analysis and chromosomal localization of retrotransposons in sugar beet (Beta vulgaris L.): LINEs andTy1-copia-like elements as major components of the genome
Schmidt, T., Kubis, S. E., & Heslop-Harrison, J. S. (1995) · Chromosome Research · doi:10.1007/bf00710014 · Cited by 82
Multiple Non-LTR Retrotransposons in the Genome of Arabidopsis thaliana
Wright, D. A., Ning, K., Smalle, J., Hauge, B. M., Goodman, H. M., & Voytas, D. F. (1996) · Genetics · doi:10.1093/genetics/142.2.569 · Cited by 82
Integration, regulation, and long-term stability of R2 retrotransposons
Eickbush, T. H., & Eickbush, D. G. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0011-2014 · Cited by 81
Self-citation
Sequence variability within the tobacco retrotransposon Tnt1 population.
Casacuberta, J., Vernhettes, S., & Grandbastien, M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07265.x · Cited by 81
The adventures of the Ty1-copia group of retrotransposons in plants
Kumar, A. (1996) · Trends in Genetics · doi:10.1016/0168-9525(96)81393-x · Cited by 81
Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription.
Tavis, J. E., & Ganem, D. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.9.4107 · Cited by 81
The Immunological Conundrum of Endogenous Retroelements
Kassiotis, G. (2023) · Annual Review of Immunology · doi:10.1146/annurev-immunol-101721-033341 · Cited by 81

Authors: Xiong, Y., & Eickbush, T. H.
Affiliations: University of Rochester (US)
ORCID: Xiong, Y.
Venue: The EMBO Journal
Publisher: Springer Science and Business Media LLC
Published: 1990-10-01
Volume: 9
Issue: 10
Pages: 3353-3362
ISSN: 0261-4189 (ISSN-L)
1460-2075
DOI: 10.1002/j.1460-2075.1990.tb07536.x
PMC: PMC552073
OpenAlex: W1554644662
Cited by: 1,374
References: 77
Citations by year: 2026: 16 · 2025: 19 · 2024: 12 · 2023: 20 · 2022: 21 · 2021: 20 · 2020: 15 · 2019: 18 · 2018: 22 · 2017: 28 · 2016: 29 · 2015: 34 · 2014: 32 · 2013: 44 · 2012: 29
FWCI: 87.47
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: www.springer.com/tdm (tdm)
www.springer.com/tdm (vor)
Locations: The EMBO Journal (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Keywords: retroelements, reverse transcriptase, retrotransposons, RNA-dependent RNA polymerase, positive-strand RNA viruses, LTR retrotransposons, retroviral evolution, hepadnaviruses, group II introns, organelle DNA, common ancestor, horizontal gene transfer
MeSH terms: Amino Acid Sequence, Animals, DNA Transposable Elements, Biological Evolution, Humans, Introns, Molecular Sequence Data, Phylogeny, RNA-Directed DNA Polymerase, DNA-Directed RNA Polymerases, Sequence Homology, Nucleic Acid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Origin and evolution of retroelements based upon their reverse transcriptase sequences

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks