Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

Identification of c- MYC as a Target of the APC Pathway

He, T.-C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., & Kinzler, K. W. (1998) · Science · doi:10.1126/science.281.5382.1509 · Cited by 4,566

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma

Korinek, V., Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B., & Clevers, H. (1997) · Science · doi:10.1126/science.275.5307.1784 · Cited by 2,905

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destrée, O., & Clevers, H. (1996) · Cell · doi:10.1016/s0092-8674(00)80112-9 · Cited by 1,824

Wnt signalling and its impact on development and cancer

Klaus, A., & Birchmeier, W. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2389 · Cited by 1,595

Caught up in a Wnt storm: Wnt signaling in cancer

Giles, R. H., van Es, J. H., & Clevers, H. (2003) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/s0304-419x(03)00005-2 · Cited by 1,482

The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF

Ishitani, T., Ninomiya-Tsuji, J., Nagai, S.-I., Nishita, M., Meneghini, M., Barker, N., Waterman, M., Bowerman, B., Clevers, H., Shibuya, H., et al. (1999) · Nature · doi:10.1038/21674 · Cited by 621

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

Giese, K., Kingsley, C., Kirshner, J. R., & Grosschedl, R. (1995) · Genes & Development · doi:10.1101/gad.9.8.995 · Cited by 541

Wnt Signaling Regulates B Lymphocyte Proliferation through a LEF-1 Dependent Mechanism

Reya, T., O'Riordan, M., Okamura, R., Devaney, E., Willert, K., Nusse, R., & Grosschedl, R. (2000) · Immunity · doi:10.1016/s1074-7613(00)00004-2 · Cited by 450

Interaction of Nuclear Receptors with the Wnt/β-Catenin/Tcf Signaling Axis: Wnt You Like to Know?

Mulholland, D. J., Dedhar, S., Coetzee, G. A., & Nelson, C. C. (2005) · Endocrine Reviews · doi:10.1210/er.2003-0034 · Cited by 377

Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity

Zhang, J. A., Mortazavi, A., Williams, B. A., Wold, B. J., & Rothenberg, E. V. (2012) · Cell · doi:10.1016/j.cell.2012.01.056 · Cited by 337

POP-1 and Anterior–Posterior Fate Decisions in C. elegans Embryos

Lin, R., Hill, R. J., & Priess, J. R. (1998) · Cell · doi:10.1016/s0092-8674(00)80917-4 · Cited by 282

Critical Involvement of Tcf-1 in Expansion of Thymocytes

Schilham, M. W., Wilson, A., Moerer, P., Benaissa-Trouw, B. J., Cumano, A., & Clevers, H. C. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.8.3984 · Cited by 237

Regulation of Lymphoid Enhancer Factor 1/T-Cell Factor by Mitogen-Activated Protein Kinase-Related Nemo-Like Kinase-Dependent Phosphorylation in Wnt/β-Catenin Signaling

Ishitani, T., Ninomiya-Tsuji, J., & Matsumoto, K. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.4.1379-1389.2003 · Cited by 212

T cell factor 1: A master regulator of the T cell response in disease

Escobar, G., Mangani, D., & Anderson, A. C. (2020) · Science Immunology · doi:10.1126/sciimmunol.abb9726 · Cited by 211

WNT Signaling and Lymphocyte Development

van de Wetering, M., de Lau, W., & Clevers, H. (2002) · Cell · doi:10.1016/s0092-8674(02)00709-2 · Cited by 139

The biochemical role of SRY in sex determination

R. Harley, V., & N. Goodfellow, P. (1994) · Molecular Reproduction and Development · doi:10.1002/mrd.1080390211 · Cited by 114

Lymphoid enhancer factor/T cell factor expression in colorectal cancer

Waterman, M. L. (2004) · Cancer and Metastasis Reviews · doi:10.1023/a:1025858928620 · Cited by 106

The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing

Hovanes, K., Li, T. W. H., & Waterman, M. L. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.9.1994 · Cited by 101

Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells

Yao, C. J., Works, K., Romagnoli, P. A., & Austin, G. E. (2005) · Leukemia · doi:10.1038/sj.leu.2403918 · Cited by 40

The Hippo pathway effector Yki downregulates Wg signaling to promote retinal differentiation in the Drosophila eye

Wittkorn, E., Sarkar, A., Garcia, K., Kango-Singh, M., & Singh, A. (2015) · Development · doi:10.1242/dev.117358 · Cited by 39

GRG5/AES Interacts with T-Cell Factor 4 (TCF4) and Downregulates Wnt Signaling in Human Cells and Zebrafish Embryos

Costa, Â. M. S., Pereira-Castro, I., Ricardo, E., Spencer, F., Fisher, S., & Costa, L. T. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067694 · Cited by 13

Tau-tubulin kinase 2 restrains microtubule-depolymerizer KIF2A to support primary cilia growth

Benk Vysloužil, D., Bernatík, O., Lánská, E., Renzová, T., Binó, L., Lacigová, A., Drahošová, T., Lánský, Z., & Čajánek, L. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02072-8 · Cited by 11

Visualizing WNT signaling in mammalian systems

van der Wal, T., & van Amerongen, R. (2023) · Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2023.02.001 · Cited by 2