WNT Signaling and Lymphocyte Development
Open accessAbstract
Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.
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The Wnt signalling pathway is an important regulator in all developmental stages of T-cells.
“Furthermore, with regard to T-cell development, the Wnt signalling pathway has been described as an important regulator in all developmental stages of T-cells [42,43,44].”
From Nemo-Like Kinase in Development and Diseases: Insights from Mouse Studies (2020) · cites this paper as [43]
Cites
Polakis, P. (2000) · Genes & Development · doi:10.1101/gad.14.15.1837 · Cited by 3,183 · see citing works
Functional interaction of β-catenin with the transcription factor LEF-1
Behrens, J., von Kries, J. P., Kühl, M., Bruhn, L., Wedlich, D., Grosschedl, R., & Birchmeier, W. (1996) · Nature · doi:10.1038/382638a0 · Cited by 2,912 · see citing works
RAG-1-deficient mice have no mature B and T lymphocytes
Mombaerts, P., Iacomini, J., Johnson, R. S., Herrup, K., Tonegawa, S., & Papaioannou, V. E. (1992) · Cell · doi:10.1016/0092-8674(92)90030-g · Cited by 2,898 · see citing works
β‐catenin is a target for the ubiquitin–proteasome pathway
Aberle, H., Bauer, A., Stappert, J., Kispert, A., & Kemler, R. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3797 · Cited by 2,533 · see citing works
XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos
Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destrée, O., & Clevers, H. (1996) · Cell · doi:10.1016/s0092-8674(00)80112-9 · Cited by 1,824 · see citing works
Self-citationDepletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
Kořínek, V., Barker, N., Moerer, P., van Donselaar, E. G., Huls, G. A., Peters, P. J., & Clevers, H. C. (1998) · Nature Genetics · doi:10.1038/1270 · Cited by 1,580 · see citing works
Self-citationLinking Colorectal Cancer to Wnt Signaling
Bienz, M., & Clevers, H. C. (2000) · Cell · doi:10.1016/s0092-8674(00)00122-7 · Cited by 1,516 · see citing works
Self-citationA new member of the frizzled family from Drosophila functions as a Wingless receptor
Bhanot, P., van den Brink, M. R. M., Samos, C. H., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, D. J., Nathans, J., & Nusse, R. (1996) · Nature · doi:10.1038/382225a0 · Cited by 1,504 · see citing works
Wetering, M. L. V. D., Cavallo, R. A., Dooijes, D., van Beest, M., van Es, J. V., Loureiro, J., Ypma, A., Hursh, D., Jones, T. L., Bejsovec, A., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)81925-x · Cited by 1,347 · see citing works
Self-citationLDL-receptor-related proteins in Wnt signal transduction
Tamai, K., Semënov, M. V., Kato, Y., Spokony, R. F., Liu, C., Katsuyama, Y., Hess, F. J., Saint‐Jeannet, J., & He, X. (2000) · Nature · doi:10.1038/35035117 · Cited by 1,334 · see citing works
Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β
Behrens, J., Jerchow, B., Würtele, M., Grimm, J., Asbrand, C., Wirtz, R. M., Kühl, M., Wedlich, D., & Birchmeier, W. (1998) · Science · doi:10.1126/science.280.5363.596 · Cited by 1,255 · see citing works
Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S., & Kikuchi, A. (1998) · The EMBO Journal · doi:10.1093/emboj/17.5.1371 · Cited by 1,248 · see citing works
Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene
Harada, N., Tamai, Y., Ishikawa, T., Sauer, B., Takaku, K., Oshima, M., & Taketo, M. M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.21.5931 · Cited by 1,198 · see citing works
Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
Mombaerts, P., Clarke, A. R., Rudnicki, M. A., Iacomini, J., Itohara, S., Lafaille, J. J., Wang, L., Ichikawa, Y., Jaenisch, R., Hooper, M., et al. (1992) · Nature · doi:10.1038/360225a0 · Cited by 1,114 · see citing works
An LDL-receptor-related protein mediates Wnt signalling in mice
Pinson, K. I., Brennan, J., Monkley, S. J., Avery, B. J., & Skarnes, W. C. (2000) · Nature · doi:10.1038/35035124 · Cited by 1,086 · see citing works
van Genderen, C., Okamura, R., Fariñas, I., Quo, R. G., Parslow, T., Bruhn, L., & Grosschedl, R. (1994) · Genes & Development · doi:10.1101/gad.8.22.2691 · Cited by 1,031 · see citing works
Profound block in thymocyte development in mice lacking p56lck
Molina, T. J., Kishihara, K., Siderovski, D. P., van Ewijk, W., Narendran, A., Timms, E. M., Wakeham, A. C., Paige, C. J., Hartmann, K.-U., Veillette, A., et al. (1992) · Nature · doi:10.1038/357161a0 · Cited by 970 · see citing works
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
Wehrli, M., Dougan, S. T., Caldwell, K. A., O’Keefe, L. V., Schwartz, S. L., Vaizel-Ohayon, D., Schejter, E. D., Tomlinson, A., & DiNardo, S. (2000) · Nature · doi:10.1038/35035110 · Cited by 871 · see citing works
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G., & Kemler, R. (1996) · Mechanisms of Development · doi:10.1016/0925-4773(96)00597-7 · Cited by 855 · see citing works
Drosophila Tcf and Groucho interact to repress Wingless signalling activity
Cavallo, R. A., Cox, R. T., Moline, M. M., Roose, J., Polevoy, G. A., Clevers, H., Peifer, M., & Bejsovec, A. (1998) · Nature · doi:10.1038/26982 · Cited by 730 · see citing works
Self-citationGiese, K., Cox, J. S., & Grosschedl, R. (1992) · Cell · doi:10.1016/0092-8674(92)90129-z · Cited by 685 · see citing works
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
Roose, J. P., Molenaar, M., Peterson, J., Hurenkamp, J., Brantjes, H., Moerer, P., van de Wetering, M., Destrée, O., & Clevers, H. C. (1998) · Nature · doi:10.1038/26989 · Cited by 674 · see citing works
Self-citationTravis, A., Amsterdam, A., Bélanger, C., & Grosschedl, R. (1991) · Genes & Development · doi:10.1101/gad.5.5.880 · Cited by 614 · see citing works
An HMG-box-containing T-cell factor required for thymocyte differentiation
Verbeek, S., Izon, D., Hofhuis, F., Robanus-Maandag, E., Riele, H. T., van de Watering, M., Oosterwegel, M., Wilson, A., Macdonald, H., & Clevers, H. (1995) · Nature · doi:10.1038/374070a0 · Cited by 585 · see citing works
Self-citationWetering, M., Oosterwegel, M., Dooijes, D., & Clevers, H. (1991) · EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07928.x · Cited by 546 · see citing works
Self-citationKishida, S., Yamamoto, H., Ikeda, S., Kishida, M., Sakamoto, I., Koyama, S., & Kikuchi, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.18.10823 · Cited by 491 · see citing works
Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- micePreprint
Galcerán, J., Fariñas, I., Depew, M. J., Clevers, H. C., & Grosschedl, R. (1999) · Genes & Development · doi:10.1101/gad.13.6.709 · Cited by 462 · see citing works
Self-citationβ-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
Hovanes, K., Li, T. W. H., Munguia, J. E., Truong, T., Milovanović, T., Marsh, J., Holcombe, R. F., & Waterman, M. L. (2001) · Nature Genetics · doi:10.1038/ng0501-53 · Cited by 458 · see citing works
Wnt Signaling Regulates B Lymphocyte Proliferation through a LEF-1 Dependent Mechanism
Reya, T., O'Riordan, M., Okamura, R., Devaney, E., Willert, K., Nusse, R., & Grosschedl, R. (2000) · Immunity · doi:10.1016/s1074-7613(00)00004-2 · Cited by 450 · see citing works
Crystal Structure of a β-Catenin/Tcf Complex
Graham, T. A., Weaver, C. I., Mao, F., Kimelman, D., & Xu, W. (2000) · Cell · doi:10.1016/s0092-8674(00)00192-6 · Cited by 406 · see citing works
Altered T cell development in mice with a targeted mutation of the CD3‐epsilon gene.
Malissen, M., Gillet, A., Ardouin, L., Bouvier, G., Trucy, J., Ferrier, P., Vivier, É., & MALISSEN, B. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00146.x · Cited by 405 · see citing works
Kishida, S., Yamamoto, H., Hino, S.-I., Ikeda, S., Kishida, M., & Kikuchi, A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4414 · Cited by 400 · see citing works
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1
Galcerán, J., Miyashita-Lin, E. M., Devaney, E. J., Rubenstein, J. L. R., & Grosschedl, R. (2000) · Development · doi:10.1242/dev.127.3.469 · Cited by 399 · see citing works
Cook, D., Fry, M., Hughes, K., Sumathipala, R., Woodgett, J. R., & Dale, T. C. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00830.x · Cited by 388 · see citing works
dishevelled and armadillo act in the Wingless signalling pathway in Drosophila
Noordermeer, J. N., Klingensmith, J., Perrimon, N., & Nusse, R. (1994) · Nature · doi:10.1038/367080a0 · Cited by 378 · see citing works
Waterman, M. L., Fischer, W. H., & Jones, K. A. (1991) · Genes & Development · doi:10.1101/gad.5.4.656 · Cited by 359 · see citing works
Ancestry and diversity of the HMG box superfamily
Laudet, V., Stéhelin, D., & Clevers, H. C. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.10.2493 · Cited by 334 · see citing works
Self-citationOkamura, R. M., Sigvardsson, M., Galcerán, J., Verbeek, S. J., Clevers, H. C., & Grosschedl, R. (1998) · Immunity · doi:10.1016/s1074-7613(00)80454-9 · Cited by 333 · see citing works
Self-citationKořínek, V., Barker, N., Willert, K., Molenaar, M., Roose, J. P., Wagenaar, G. T. M., Markman, M. W. M., Lamers, W., Destrée, O., & Clevers, H. C. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.3.1248 · Cited by 326 · see citing works
Self-citationThe Yin-Yang of TCF/β-Catenin Signaling
Barker, N., Morin, P. J., & Clevers, H. C. (1999) · Advances in cancer research · doi:10.1016/s0065-230x(08)60783-6 · Cited by 292 · see citing works
Self-citationALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function.Preprint
Bruhn, L., Munnerlyn, A., & Grosschedl, R. (1997) · Genes & Development · doi:10.1101/gad.11.5.640 · Cited by 281 · see citing works
DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1.Preprint
Giese, K., Amsterdam, A., & Grosschedl, R. (1991) · Genes & Development · doi:10.1101/gad.5.12b.2567 · Cited by 263 · see citing works
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
Brannon, M. K., Brown, J. D., Bates, R. L., Kimelman, D., & Moon, R. T. (1999) · Development · doi:10.1242/dev.126.14.3159 · Cited by 247 · see citing works
Interaction of Axin and Dvl‐2 proteins regulates Dvl‐2‐stimulated TCF‐dependent transcription
Smalley, M. J., Sara, E., Paterson, H., Naylor, S., Cook, D., Jayatilake, H., Fryer, L. G. D., Hutchinson, L., Fry, M., & Dale, T. C. (1999) · The EMBO Journal · doi:10.1093/emboj/18.10.2823 · Cited by 247 · see citing works
The β-catenin–TCF-1 pathway ensures CD4+CD8+ thymocyte survival
Ioannidis, V., Beermann, F., Clevers, H. C., & Held, W. (2001) · Nature Immunology · doi:10.1038/90623 · Cited by 246 · see citing works
Self-citationDifferential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis
Oosterwegel, M. A., van de Wetering, M., Timmerman, J. J., Kruisbeek, A. M., Destrée, O., Meijlink, F. C. P. W., & Clevers, H. C. (1993) · Development · doi:10.1242/dev.118.2.439 · Cited by 246 · see citing works
Self-citationCritical Involvement of Tcf-1 in Expansion of Thymocytes
Schilham, M. W., Wilson, A., Moerer, P., Benaissa-Trouw, B. J., Cumano, A., & Clevers, H. C. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.8.3984 · Cited by 237 · see citing works
Self-citationTcf4 can specifically recognize beta-catenin using alternative conformations.
Graham, T. A., Ferkey, D. M., Mao, F., Kimelman, D., & Xu, W. (2001) · Nature Structural Biology · doi:10.1038/nsb718 · Cited by 216 · see citing works
Structure of a human Tcf4-beta-catenin complex.
Poy, F., Lepourcelet, M., Shivdasani, R. A., & Eck, M. J. (2001) · Nature Structural Biology · doi:10.1038/nsb720 · Cited by 200 · see citing works
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
Staal, F. J. T., Meeldijk, J., Moerer, P., Jay, P., van de Weerdt, B. C. M., Vainio, S. J., Nolan, G. P., & Clevers, H. C. (2001) · European Journal of Immunology · doi:10.1002/1521-4141(200101)31:1 · Cited by 200 · see citing works
Self-citationvan de Wetering, M., Castrop, J., Kořínek, V., & Clevers, H. C. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.3.745 · Cited by 191 · see citing works
Self-citationGounari, F., Aifantis, I., Khazaie, K., Hoeflinger, S., Harada, N., Taketo, M. M., & von Boehmer, H. (2001) · Nature Immunology · doi:10.1038/ni0901-863 · Cited by 167 · see citing works
Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro.Preprint
Sheridan, P. L., Sheline, C. T., Cannon, K. S., Voz, M. L., Pazin, M. J., Kadonaga, J. T., & Jones, K. A. (1995) · Genes & Development · doi:10.1101/gad.9.17.2090 · Cited by 159 · see citing works
Giese, K., & Grosschedl, R. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06155.x · Cited by 159 · see citing works
Carlsson, P., Waterman, M. L., & Jones, K. A. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2418 · Cited by 154 · see citing works
Oosterwegel, M. A., van de Wetering, M., Dooijes, D., Klomp, L. W. J., Winoto, A., Georgopoulos, K., Meijlink, F. C. P. W., & Clevers, H. C. (1991) · The Journal of Experimental Medicine · doi:10.1084/jem.173.5.1133 · Cited by 142 · see citing works
Self-citationHattori, N., Kawamoto, H., Fujimoto, S., Kuno, K., & Katsura, Y. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.3.1137 · Cited by 142 · see citing works
Mayall, T. P., Sheridan, P. L., Montminy, M. R., & Jones, K. A. (1997) · Genes & Development · doi:10.1101/gad.11.7.887 · Cited by 118 · see citing works
Sequence-specific HMG box factors recognize 10-12 base pair minor groove motifs
van Beest, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004102200 · Cited by 112 · see citing works
Sequence-specific High Mobility Group Box Factors Recognize 10–12-Base Pair Minor Groove Motifs
van Beest, M., Dooijes, D., van de Wetering, M., Kjærulff, S., Bonvin, A. M. J. J., Nielsen, O., & Clevers, H. C. (2000) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61506-1 · Cited by 101 · see citing works
Self-citationHovanes, K., Li, T. W. H., & Waterman, M. L. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.9.1994 · Cited by 101 · see citing works
Interaction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction
Itoh, K., Antipova, A. A., Ratcliffe, M., & Sokol, S. Y. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.2228-2238.2000 · Cited by 95 · see citing works
Prieve, M. G., & Waterman, M. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4503 · Cited by 90 · see citing works
Clonal Acquisition of the Ly49A NK Cell Receptor Is Dependent on the trans-Acting Factor TCF-1
Held, W., Kunz, B., Lowin, B., van de Wetering, M., & Clevers, H. C. (1999) · Immunity · doi:10.1016/s1074-7613(00)80118-1 · Cited by 84 · see citing works
Self-citationvan de Wetering, M., Oosterwegel, M. A., Holstege, F. C. P., Dooyes, D., Suijkerbuijk, R. F., van Kessel, A. G., & Clevers, H. C. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42476-3 · Cited by 43 · see citing works
Self-citationDooijes, D., van de Wetering, M., Knippels, L. M. J., & Clevers, H. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74537-2 · Cited by 36 · see citing works
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Reya, T., & Clevers, H. (2005) · Nature · doi:10.1038/nature03319 · Cited by 3,666 · see citing works
Self-citationWyss-Coray (2006) · doi:10.1038/nm1484 · Cited by 1,284 · see citing works
Endothelial cell–cell junctions: happy together
Dejana, E. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1357 · Cited by 1,184 · see citing works
The circadian clock: pacemaker and tumour suppressor
Fu, L., & Lee, C. C. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1072 · Cited by 678 · see citing works
The Wnt signaling pathway and its role in tumor development
Lustig, B., & Behrens, J. (2003) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-003-0431-0 · Cited by 521 · see citing works
Lampugnani, M. G., Zanetti, A., Corada, M., Takahashi, T., Balconi, G., Breviario, F., Orsenigo, F., Cattelino, A., Kemler, R., Daniel, T. O., et al. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200209019 · Cited by 410 · see citing works
Bcl11b is required for differentiation and survival of αβ T lymphocytes
Wakabayashi, Y., Watanabe, H., Inoue, J., Takeda, N., Sakata, J., Mishima, Y., Hitomi, J., Yamamoto, T., Utsuyama, M., Niwa, O., et al. (2003) · Nature Immunology · doi:10.1038/ni927 · Cited by 356 · see citing works
β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis
Cobas, M., Wilson, A., Ernst, B., Mancini, S., Macdonald, H., Kemler, R., & Radtke, F. (2004) · Journal of Experimental Medicine · doi:10.1084/jem.20031615 · Cited by 401 · see citing works
Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2
Oshima, T., Abe, M., Asano, J., Hara, T., Kitazoe, K.-I., Sekimoto, E., Tanaka, Y., Shibata, H., Hashimoto, T., Ozaki, S., et al. (2005) · Blood · doi:10.1182/blood-2004-12-4940 · Cited by 344 · see citing works
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Bafico, A., Liu, G., Goldin, L., Harris, V., & Aaronson, S. A. (2004) · Cancer Cell · doi:10.1016/j.ccr.2004.09.032 · Cited by 321 · see citing works
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Kikuchi, A., Yamamoto, H., Sato, A., & Matsumoto, S. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02294.x · Cited by 317 · see citing works
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Derksen, P. W. B., Tjin, E. P. M., Meijer, H. P., Klok, M. D., MacGillavry, H. D., van Oers, M. H. J., Lokhorst, H. M., Bloem, A. C., Clevers, H. C., Nusse, R., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305855101 · Cited by 306 · see citing works
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Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
Balc̆iūnaite, G., Keller, M. P., Balciunaite, E., Piali, L., Žuklys, S., Mathieu, Y., Gill, J. W., Boyd, R. L., Sussman, D. J., & Holländer, G. A. (2002) · Nature Immunology · doi:10.1038/ni850 · Cited by 261 · see citing works
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Rosenbauer, F., Owens, B. M., Yu, L., Tumang, J. R., Steidl, U., Kutok, J. L., Clayton, L. K., Wagner, K., Scheller, M., Iwasaki, H., et al. (2006) · Nature Genetics · doi:10.1038/ng1679 · Cited by 237 · see citing works
Maillard, I. P., Adler, S. H., & Pear, W. S. (2003) · Immunity · doi:10.1016/s1074-7613(03)00325-x · Cited by 219 · see citing works
Willinger, T., Freeman, T. C., Herbert, M., Hasegawa, H., McMichael, A. J., & Callan, M. F. C. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.3.1439 · Cited by 197 · see citing works
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Notani, D., Gottimukkala, K. P., Jayani, R. S., Limaye, A. S., Damle, M., Mehta, S. S., Purbey, P. K., Joseph, J., & Galande, S. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000296 · Cited by 198 · see citing works
Testing the Circadian Gene Hypothesis in Prostate Cancer: A Population-Based Case-Control Study
Zhu, Y. L., Stevens, R. G., Hoffman, A. E., FitzGerald, L. M., Kwon, E. M., Ostrander, E. A., Davis, S., Zheng, T., & Stanford, J. L. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0648 · Cited by 169 · see citing works
Attenuated Wnt Signaling Perturbs Pancreatic Growth but Not Pancreatic Function
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Mukherjee, S., Mazumdar, M., Chakraborty, S., Manna, A., Saha, S., Khan, P., Bhattacharjee, P., Guha, D., Adhikary, A., Mukherjee, S., et al. (2014) · Stem Cell Research & Therapy · doi:10.1186/scrt506 · Cited by 151 · see citing works
The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis
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Identification of a global gene expression signature of B-chronic lymphocytic leukemia.
Jelinek, D. F., Tschumper, R. C., Stolovitzky, G. A., Iturria, S. J., Tu, Y., Lepre, J., Shah, N. H., & Kay, N. E. (2003) · PubMed · Cited by 131 · see citing works
Taniuchi, K., Nakagawa, H., Nakamura, T., Eguchi, H., Ohigashi, H., Ishikawa, O., Katagiri, T., & Nakamura, Y. (2005) · Cancer Research · doi:10.1158/0008-5472.105.65.1 · Cited by 129 · see citing works
Badders, N. M., Goel, S., Clark, R. J., Klos, K. S., Kim, S. Y., Bafico, A., Lindvall, C. J., Williams, B. O., & Alexander, C. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006594 · Cited by 127 · see citing works
Identification of Target Genes of the p16INK4A-pRB-E2F Pathway
Vernell, R., Helin, K., & Müller, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304930200 · Cited by 121 · see citing works
Guo, Z., Dose, M., Kovalovsky, D., Chang, R., O’Neil, J., Look, A. T., von Boehmer, H., Khazaie, K., & Gounari, F. (2007) · Blood · doi:10.1182/blood-2006-11-059071 · Cited by 121 · see citing works
c-Myc mediates pre-TCR-induced proliferation but not developmental progression
Dose, M., Khan, I., Guo, Z., Kovalovsky, D., Krueger, A., von Boehmer, H., Khazaie, K., & Gounari, F. (2006) · Blood · doi:10.1182/blood-2006-02-005900 · Cited by 120 · see citing works
Frizzled 9 knock-out mice have abnormal B-cell development
Ranheim, E. A., Kwan, H. C. K., Reya, T., Wang, Y.-K., Weissman, I. L., & Francke, U. (2004) · Blood · doi:10.1182/blood-2004-06-2334 · Cited by 117 · see citing works
Loss of adenomatous polyposis coli gene function disrupts thymic development
Gounari, F., Chang, R., Cowan, J. M., Guo, Z., Dose, M., Gounaris, E. G., & Khazaie, K. (2005) · Nature Immunology · doi:10.1038/ni1228 · Cited by 108 · see citing works
Chen, A., & Kong, L. (2018) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2018.08.002 · Cited by 106 · see citing works
Wnt signaling in the stem cell niche
Rattis, F. M., Voermans, C., & Reya, T. (2004) · Current Opinion in Hematology · doi:10.1097/01.moh.0000133649.61121.ec · Cited by 106 · see citing works
Liu, P., Xu, B., Shen, W., Zhu, H., Wu, W., Fu, Y., Chen, H., Dong, H., Zhu, Y., Miao, K., et al. (2011) · Leukemia · doi:10.1038/leu.2011.357 · Cited by 104 · see citing works
Gene expression analysis of B‐lymphoma cells resistant and sensitive to bortezomib*
Shringarpure, R., Catley, L. P., Bhole, D., Burger, R., Podar, K., Tai, Y., Kessler, B. M., Galardy, P. J., Ploegh, H. L., Tassone, P., et al. (2006) · British Journal of Haematology · doi:10.1111/j.1365-2141.2006.06132.x · Cited by 98 · see citing works
Gene expression profiling reveals a highly specialized genetic program of plasma cells
Underhill, G. H., George, D., Bremer, E. G., & Kansas, G. S. (2003) · Blood · doi:10.1182/blood-2002-08-2673 · Cited by 93 · see citing works
Alternative Splicing of SLC39A14 in Colorectal Cancer is Regulated by the Wnt Pathway
Thorsen, K., Mansilla, F., Schepeler, T., Øster, B., Rasmussen, M. H., Dyrskjøt, L., Karni, R., Akerman, M., Krainer, A. R., Laurberg, S., et al. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m110.002998 · Cited by 90 · see citing works
Staal, F. J. T., & Clevers, H. C. (2003) · Current Opinion in Immunology · doi:10.1016/s0952-7915(03)00003-7 · Cited by 86 · see citing works
Self-citationPortis, T., & Longnecker, R. (2002) · Journal of Virology · doi:10.1128/jvi.77.1.105-114.2003 · Cited by 81 · see citing works
Catalano, V., Dentice, M., Ambrosio, R., Luongo, C., Carollo, R., Benfante, A., Todaro, M., Stassi, G., & Salvatore, D. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-1542 · Cited by 79 · see citing works
Barandon, L., Casassus, F., Leroux, L., Moreau, C., Allières, C., Lamazière, J. D., Dufourcq, P., Couffinhal, T., & Duplàa, C. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.232280 · Cited by 74 · see citing works
Kennell, J. A., O’Leary, E. E., Gummow, B. M., Hammer, G. D., & MacDougald, O. A. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5366-5375.2003 · Cited by 73 · see citing works
B-cell commitment: deciding on the players
Hardy, R. R. (2003) · Current Opinion in Immunology · doi:10.1016/s0952-7915(03)00012-8 · Cited by 72 · see citing works
Age‐related alterations of gene expression patterns in human CD8<sup>+</sup> T cells
Cao, J., Gollapudi, S., Sharman, E. H., Jia, Z., & Gupta, S. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2009.00534.x · Cited by 71 · see citing works
Spagnuolo, R. (2003) · Blood · doi:10.1182/blood-2003-07-2459 · Cited by 71 · see citing works
Insect galectins: Roles in immunity and development
Pace, K. E., & Baum, L. G. (2002) · Glycoconjugate Journal · doi:10.1023/b:glyc.0000014092.86763.2f · Cited by 67 · see citing works
Osada, M., Jardine, L., Misir, R., Andl, T., Millar, S. E., & Pezzano, M. T. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009062 · Cited by 61 · see citing works
Subversion of T lineage commitment by PU.1 in a clonal cell line system
Dionne, C. J., Tse, K. Y., Weiss, A. H., Franco, C. B., Wiest, D. L., Anderson, M. K., & Rothenberg, E. V. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.01.027 · Cited by 54 · see citing works
Guinot, A., Oeztuerk-Winder, F., & Ventura, J. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-3302 · Cited by 53 · see citing works
Circadian clock circuitry in colorectal cancer
Mazzoccoli, G. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i15.4197 · Cited by 47 · see citing works
Dorfman, D. M., Greisman, H. A., & Shahsafaei, A. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64287-3 · Cited by 48 · see citing works
Rui, Q., Dong, S., Jiang, W., & Wang, D. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.109782 · Cited by 47 · see citing works
Role of WNT signaling in normal and malignant hematopoiesis.
Khan, N. I., & Bendall, L. J. (2006) · PubMed · doi:10.14670/hh-21.761 · Cited by 47 · see citing works
Pathogen-specific TLR2 Protein Activation Programs Macrophages to Induce Wnt-β-Catenin Signaling
Bansal, K., Trinath, J., Chakravortty, D., Patil, S. A., & Balaji, K. N. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.260414 · Cited by 46 · see citing works
RetractedLong-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail☆
Lin, M., & Kopan, R. (2003) · Developmental Biology · doi:10.1016/j.ydbio.2003.07.007 · Cited by 45 · see citing works
Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages
Kamimura, K., Mishima, Y., Obata, M., Endo, T., Aoyagi, Y., & Kominami, R. (2007) · Oncogene · doi:10.1038/sj.onc.1210388 · Cited by 44 · see citing works
Transcriptional Regulation of CD4 Gene Expression by T Cell Factor-1/β-Catenin Pathway
Huang, Z., Xie, H., Ioannidis, V., Held, W., Clevers, H. C., Sadim, M. S., & Sun, Z. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.8.4880 · Cited by 44 · see citing works
Self-citationYang, H., Youm, Y., Sun, Y., Rim, J., Galbán, C. J., Vandanmagsar, B., & Dixit, V. D. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.1008621 · Cited by 44 · see citing works
Fabbri, A., Cossa, M., Sonzogni, A., Bidoli, P., Canova, S., Cortinovis, D. L., Abbate, M. I., Calabrese, F., Nannini, N., Lunardi, F., et al. (2017) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-017-2130-2 · Cited by 42 · see citing works
VE-Cadherin Expression and Clustering Maintain Low Levels of Survivin in Endothelial Cells
Iurlaro, M., Demontis, F., Corada, M., Zanetta, L., Drake, C., Gariboldi, M., Peiró, S., Cano, A., Navarro, P., Cattelino, A., et al. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63287-7 · Cited by 42 · see citing works
Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line
Buckley, S. M., Ulloa‐Montoya, F., Abts, D., Oostendorp, R. A. J., Dzierzak, E. A., Ekker, S. C., & Verfaillie, C. M. (2010) · Experimental Hematology · doi:10.1016/j.exphem.2010.09.010 · Cited by 40 · see citing works
Plakoglobin Is O-Glycosylated Close to the N-terminal Destruction Box
Hatsell, S. J., Medina, L., Merola, J., Haltiwanger, R. S., & Cowin, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301346200 · Cited by 40 · see citing works
Braunstein, M., & Anderson, M. K. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/678705 · Cited by 39 · see citing works
Ichii, M., Oritani, K., Yokota, T., Nishida, M., Takahashi, I., Shirogane, T., Ezoe, S., Saitoh, N., Tanigawa, R., Kincade, P. W., et al. (2008) · Experimental Hematology · doi:10.1016/j.exphem.2007.12.013 · Cited by 39 · see citing works
Li, F., Person, R., Takemaru, K., Williams, K., Meade-White, K. D., Ozsahin, A. H., Güngör, T., Moon, R. T., & Horwitz, M. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310759200 · Cited by 39 · see citing works
Hughes, T. A., & Brady, H. J. M. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.09.014 · Cited by 38 · see citing works
Regulation of T-cell receptor Dβ1 promoter by KLF5 through reiterated GC-rich motifs
Yang, X. O., Doty, R. T., Hicks, J., & Willerford, D. M. (2003) · Blood · doi:10.1182/blood-2002-08-2579 · Cited by 38 · see citing works
Wnt-10b promotes differentiation of skin epithelial cells in vitro
Ouji, Y., Yoshikawa, M., Shiroi, A., & Ishizaka, S. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.104 · Cited by 37 · see citing works
Ben-Lulu, S., Pollak, Y., Mogilner, J. G., Bejar, J., Coran, A. G., & Sukhotnik, I. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045221 · Cited by 37 · see citing works
Pal, I., Rajesh, Y., Banik, P., Dey, G., Dey, K. K., Bharti, R., Naskar, D., Chakraborty, S., Ghosh, S. K., Das, S. K., et al. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.03.008 · Cited by 36 · see citing works
Neural stem cells in the adult ciliary epithelium express GFAP and are regulated by Wnt signaling
Das, A. V., Zhao, X., James, J., Kim, M., Cowan, K. H., & Ahmad, I. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.11.064 · Cited by 36 · see citing works
Marei, H. E. S., Althani, A., Afifi, N. M., Michetti, F., Pescatori, M., D, R. P. M., Casalbore, P., Cenciarelli, C., Schwartz, P. H., & Ahmed, A.-E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028420 · Cited by 34 · see citing works
Pygopus is required for embryonic brain patterning in Xenopus
Lake, B. B., & Kao, K. R. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00305-1 · Cited by 33 · see citing works
Clinical significance of lymphoid enhancer-binding factor 1 expression in acute myeloid leukemia
Fu, Y., Zhu, H., Wu, W., Xu, J., Chen, T., Xu, B., Qian, S., Li, J., & Liu, P. (2013) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2013.805759 · Cited by 32 · see citing works
Kagoshima, H., Sawa, H., Mitani, S., Bürglin, T. R., Shigesada, K., & Kohara, Y. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.08.034 · Cited by 31 · see citing works
Role of the Wnt/β-catenin network in regulating hematopoiesis
Wilusz, M., & Majka, M. (2008) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-008-0029-y · Cited by 30 · see citing works
Wnt-10b secreted from lymphocytes promotes differentiation of skin epithelial cells
Ouji, Y., Yoshikawa, M., Shiroi, A., & Ishizaka, S. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.028 · Cited by 29 · see citing works
Swain, R. K., Katoh, M., Medina, A., & Steinbeißer, H. (2005) · Cell Communication and Signaling · doi:10.1186/1478-811x-3-12 · Cited by 29 · see citing works
Notch and lymphopoiesis: a view from the microenvironment
Parreira, L., Neves, H., & Simões, S. D. M. (2003) · Seminars in Immunology · doi:10.1016/s1044-5323(03)00004-6 · Cited by 27 · see citing works
Marei, H. E. S., Althani, A., Afifi, N. M., Abdelmaksoud, A., Bernardini, C., Michetti, F., Barba, M., Pescatori, M., Maira, G., Paldino, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082206 · Cited by 27 · see citing works
Portis, T., Ikeda, M., & Longnecker, R. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.05.009 · Cited by 27 · see citing works
LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells
Ngai, H., Barragán, G. A., Tian, G., Balzeau, J. C., Zhang, C., Courtney, A. N., Guo, L., Xu, X. Y., Wood, M. S., Drabek, J. M., et al. (2022) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-22-0333 · Cited by 26 · see citing works
Frequent β-catenin overexpression without exon 3 mutation in cutaneous lymphomas
Bellei, B., Pacchiarotti, A., Perez, M., & Faraggiana, T. (2004) · Modern Pathology · doi:10.1038/modpathol.3800181 · Cited by 25 · see citing works
Variation of LEF-1 mRNA expression in low-grade B-cell non-Hodgkin's lymphoma
Howe, D. J., & Bromidge, T. J. (2005) · Leukemia Research · doi:10.1016/j.leukres.2005.06.004 · Cited by 24 · see citing works
Recognizing Paradigm Instability in Theories of Carcinogenesis
Baker, S. G. (2014) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2014/6855 · Cited by 23 · see citing works
Cai, Y., Wu, P., Özen, M., Yu, Y., Wang, J., Ittmann, M., & Liu, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.11.041 · Cited by 22 · see citing works
Nemo-Like Kinase in Development and Diseases: Insights from Mouse Studies
Daams, R., & Massoumi, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239203 · Cited by 21 · see citing works
Membrane properties of retinal stem cells/progenitors
Das, A. V., Edakkot, S., Thoreson, W. B., James, J., Bhattacharya, S., & Ahmad, I. (2005) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2005.04.003 · Cited by 21 · see citing works
Chen, K., Huang, Y., Guo, M. M., Lin, T., Weng, W.-T., Yang, H.-J., Yang, K. D., & Kuo, H. (2018) · Oncotarget · doi:10.18632/oncotarget.25305 · Cited by 20 · see citing works
Lewintre, E. J., Martín, C. R., Montaner, D. A., Marín, M., Terol, M. J., Farrás, R., Benet, I., Calvete, J. J., Dopazo, J., & García-Conde, J. (2009) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428190802541807 · Cited by 19 · see citing works
Circadian rhythm in prostate cancer: time to take notice of the clock
Zhu, W., He, Q., Feng, D., Wei, Q., & Yang, L. (2022) · Asian Journal of Andrology · doi:10.4103/aja202255 · Cited by 18 · see citing works
Altered Mucosal Immune-Microbiota Interactions in Familial Adenomatous Polyposis
Noble, A., Durant, L. R., Dilke, S. M., Man, R., Martín, I. R., Patel, R., Hoyles, L., Pring, E. T., Latchford, A. R., Clark, S. K., et al. (2022) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000428 · Cited by 16 · see citing works
Stephanthraniline A inhibits the proliferation and activation of T cells in vitro and in vivo
Chen, F., Yang, N., Ye, Y., Sun, H., Li, X., & Xu, S. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.04.012 · Cited by 15 · see citing works
Wurster, A. L., & Pazin, M. J. (2012) · Biochemistry and Cell Biology · doi:10.1139/o11-042 · Cited by 15 · see citing works
Initiation and Limitation of Ly-49A NK Cell Receptor Acquisition by T Cell Factor-1
Ioannidis, V., Kunz, B., Tanamachi, D. M., Scarpellino, L., & Held, W. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.2.769 · Cited by 15 · see citing works
Baljinnyam, B., Klauzińska, M., Saffo, S., Callahan, R., & Rubin, J. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029455 · Cited by 13 · see citing works
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt
Liu, C., Ma, L., Wang, Y., Zhao, J., Chen, P., Chen, X., Wang, Y., Hu, Y., Liu, Y., Jia, X., et al. (2021) · Science Advances · doi:10.1126/sciadv.abg6262 · Cited by 12 · see citing works
Age-dependent transcriptomic profiles of leukocytes in pediatric population
Koutsogiannaki, S., Kim, S., & Yuki, K. (2023) · Clinical Immunology · doi:10.1016/j.clim.2023.109728 · Cited by 10 · see citing works
Tracing the path of cancer initiation: the AA protein-based model for cancer genesis
Adjiri, A. (2018) · BMC Cancer · doi:10.1186/s12885-018-4739-1 · Cited by 10 · see citing works
Nam, M., Kim, G.-Y., Yun, S.-E., Jang, J.-Y., Kim, Y.-H., Choi, E. H., Kang, S., & Rhim, H. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.95 · Cited by 10 · see citing works
- Authors
- van de Wetering, M., de Lau, W., & Clevers, H.
- Affiliations
- University Medical Center Utrecht (NL)
- Corresponding author
- Clevers, Hans
- ORCID
- Clevers, Hans
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2002-04
- Volume
- 109
- Issue
- 2
- Pages
- S13-S19
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1987938190
- Cited by
- 139
- References
- 66
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 3 · 2015: 3 · 2014: 3 · 2013: 5 · 2012: 8
- FWCI
- 1.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (publishedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Wnt/β-catenin signaling in development and cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- Wnt signaling, lymphocyte development, Notch signaling, signaling pathways, cell fate determination, vertebrate immune system
- MeSH terms
- Animals, Cell Differentiation, DNA-Binding Proteins, Humans, Lymphocytes, Proto-Oncogene Proteins, Thymus Gland, Transcription Factors, Signal Transduction, Mice, Knockout, Cell Lineage, Zebrafish Proteins, Wnt Proteins, Mice, Lymphoid Enhancer-Binding Factor 1
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