Cited by 102Personality Disorders and PsychopathologyPersonality Traits and PsychologyBipolar Disorder and Treatment

The DOI matches its Crossref record; 47 of the 54 references it cites were found in a registry or an index, and 7 are not checked yet; none of the 54 sources its claims cite is checked for support yet.

Personality disorder: a new global perspective

Open access

Abstract

Personality disorder is now being accepted as an important condition in mainstream psychiatry across the world. Although it often remains unrecognized in ordinary practice, research studies have shown it is common, creates considerable morbidity, is associated with high costs to services and to society, and interferes, usually negatively, with progress in the treatment of other mental disorders. We now have evidence that personality disorder, as currently classified, affects around 6% of the world population, and the differences between countries show no consistent variation. We are also getting increasing evidence that some treatments, mainly psychological, are of value in this group of disorders. What is now needed is a new classification that is of greater value to clinicians, and the WPA Section on Personality Disorders is currently undertaking this task.

Checked 2026-10-06 · 7 references not checked yet

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

This review argues that personality disorder is common, costly, and under-recognized worldwide, with prevalence estimates around 6% globally and 3–10% in community samples. It calls for a new, clinically useful classification and concludes that psychological treatments show promise while drug treatments lack long-term support.

Key findings

  • Recent epidemiological studies report varied prevalence: 4.4% in Great Britain (Coid et al., n=628), 14.8% in the US (Grant et al., n=43,093), and a 10-country survey (Huang et al., n=21,162) found no consistent cross-country pattern; the abstract cites around 6% globally and a 3–10% community range.
  • Comorbid personality disorder predicts poorer outcomes: meta-analytic evidence from more than 60 depression studies indicates roughly double the likelihood of non-recovery, while psychosis studies show prevalence estimates from 4.5% to 100% and poorly studied outcomes.
  • Economic burden estimates include £704 million per year in English health and social care costs for people with personality disorder in contact with general practitioners, rising to £7.9 billion with productivity losses; a Dutch estimate is £11,126 per patient.
  • Treatment and classification: psychotropic drugs are judged to have no proven long-term value; structured team psychological approaches are suggested for borderline personality disorder and cognitive/group approaches for antisocial personality disorder, with rewards preferred over punishment; three quarters of surveyed experts favored replacing DSM-IV, and the WPA Section is developing ICD-11 proposals.

Methods

  • Design: narrative global-perspective review and position paper from the WPA Section on Personality Disorders, not primary research.
  • Data: summarizes three major recent epidemiological studies (Huang et al. 2009, Coid et al. 2006, Grant et al. 2004) and reviews literature on comorbidity, costs, treatment, and classification.
  • Analysis: qualitative synthesis, including reference to a meta-analysis of more than 60 depression studies described as unpublished data and to systematic reviews of treatment trials.

Limitations

  • Stated: epidemiological studies are few because national surveys rarely assess personality disorder and lay-interviewer assessment is difficult; cost estimates rely on service attenders and therefore do not represent the whole personality disorder population, so the true cost remains unknown.
  • Stated: treatment evidence is concentrated on borderline personality disorder, with too few randomized trials for clear conclusions; evidence for other personality disorders is scant, two cluster C trials disagree, and psychosis measurement reliability and outcomes are unclear.
  • Evident from the text: as a review/position piece, it relies on selected literature and some unpublished data, and the proposed dimensional factors are acknowledged to have little validity evidence so far.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1002/j.2051-5545.2010.tb00270.x

Cites

47 of 54 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

37 Not checked yet · 16 Own interpretation · 13 No basis given

Verify all 54 references — free account

Show all 33 claims

  • It may state two separate claims as one. 21
  • Probably not a substantial claim. 15
33 of 33
  • The paper relies on this without support.

    People with severe personality disorder cause the most disruption to services and society.

    “it is the people in this group who cause the most disruption to services and to society”
  • The paper relies on this without support.

    Prevalence estimates from different countries can be meaningfully compared despite differences in methods and instruments.

    “the differences between countries show no consistent variation”
2 of 2

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

2 of 2

Citations

Cites

Show all 54 references

Research works printed but not linked: 3

  1. Newton-Howes, 2008, The prevalence of personality disorder in schizophrenia: rates and explanatory modelling, Psychol Med, 37, 1
  2. National Institute of Health and Clinical Excellence, 2009, Borderline personality disorder: treatment and management
  3. National Institute of Health and Clinical Excellence, 2009, Antisocial personality disorder: treatment, management and prevention

Cited by

Sorted by citations

Items 101–102 of 102

Metadata

Authors
TYRER, P., MULDER, R., CRAWFORD, M., NEWTON-HOWES, G., SIMONSEN, E., NDETEI, D., KOLDOBSKY, N., FOSSATI, A., MBATIA, J., & BARRETT, B.
Affiliations
  • Imperial College London (GB)
  • University of Otago (NZ)
  • University of Nairobi (KE)
  • Universidad Nacional de La Plata (AR)
  • IRCCS Ospedale San Raffaele (IT)
  • Ministry of Health and Social Welfare (TZ)
Venue
World Psychiatry
Publisher
Wiley
Published
2010-02
Volume
9
Issue
1
Pages
56-60
ISSN
1723-8617 (ISSN-L)
OpenAlex
W1754023234
Cited by
102
References
54
Citations by year
2026: 1 · 2025: 4 · 2024: 2 · 2023: 8 · 2022: 10 · 2021: 14 · 2020: 7 · 2019: 8 · 2018: 11 · 2017: 8 · 2016: 3 · 2015: 7 · 2014: 4 · 2013: 1 · 2012: 5
FWCI
5.28
Type
journal article
Language
en
Open access
Locations
  • World Psychiatry (publishedVersion)
  • PubMed Central (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
  • Americanae (AECID Library) (submittedVersion, cc-by-nc-sa)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
  • Research Portal (King's College London) (submittedVersion)
  • RUCforsk (Roskilde University) (submittedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
personality disorders, global prevalence, morbidity, service costs, psychological intervention, personality disorder classification

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