The Economic Burden of Personality Disorders in Mental Health Care
Abstract
OBJECTIVE: Some evidence suggests that personality disorders are associated with a high economic burden due to, for example, a high demand on psychiatric, health, and social care services. However, state-of-the-art cost studies for the broad range of personality disorder diagnoses are lacking. The present study examines the direct medical costs, as well as the indirect costs, of patients seeking mental health treatment with DSM-IV personality disorders. METHOD: The 1740 subjects included in this study were recruited from March 2003 to March 2006 from 6 different mental health care institutes in the Netherlands specializing in the psychotherapeutic treatment of personality disorders. The direct and indirect costs were assessed using the Trimbos and Institute for Medical Technology Assessment Questionnaire on Costs Associated with Psychiatric Illness. Personality disorders were diagnosed using the Structured Interview for DSM-IV Personality. RESULTS: The mean total costs of the personality disorder group in the 12 months prior to treatment were 11,126 euros per patient. Two thirds (66.5%) of these costs consisted of direct medical costs, while the remaining costs were related to productivity losses. Borderline and obsessive-compulsive personality disorders were uniquely associated with increased mean total costs. CONCLUSIONS: Treatment-seeking patients with personality disorders pose a high economic burden on society, a burden substantially higher than that found in, for instance, depression or generalized anxiety disorder. These high societal costs present a strong argument in favor of prioritizing effective personality disorder treatments in reimbursement decisions.
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BPD results in a high burden of disease and considerable societal costs.
“In addition, people with BPD often have poor physical health [3] and excess mortality from medical conditions [1] resulting in a high burden of disease and considerable societal costs [7, 8].”
Personality disorders have been associated with similar or higher societal costs than mood and anxiety disorders.
“Personality disorders (PDs) are now being accepted as important conditions in mainstream psychiatry and have been associated with similar or higher costs to society than mood and anxiety disorders [9–11]”
From Personality disorders are important risk factors for disability pensioning (2014) · cites this paper as [10]
Soeteman et al calculated the total burden of personality disorder in the Netherlands to be £11,126 per patient.
“They calculated the total burden of personality disorder in the Netherlands to be £11,126 per patient”
From Personality disorder: a new global perspective (2010) · cites this paper as [23]
Cites
Treatment utilization by patients with personality disorders
Bender, D. S., Dolan, R. T., Skodol, A. E., Sanislow, C. A., Dyck, I. R., McGlashan, T. H., Shea, M. T., Zanarini, M. C., Oldham, J. M., & Gunderson, J. G. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.2.295 · Cited by 779 · see citing works
Size of burden of schizophrenia and psychotic disorders
Wulf Rössler, A., Salize, H. J., van Os, J., & Riecher‐Rössler, A. (2005) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2005.04.009 · Cited by 746 · see citing works
The impact of psychiatric disorders on work loss days
Kessler, R. C., & Frank, R. G. (1997) · Psychological Medicine · doi:10.1017/s0033291797004807 · Cited by 716 · see citing works
Structured interview for DSM-IV personality: SIDP-IV
Mowry, B. J. (1998) · Australian & New Zealand Journal of Psychiatry · Cited by 592 · see citing works
Drummond, M. (1992) · PharmacoEconomics · doi:10.2165/00019053-199202010-00001 · Cited by 489 · see citing works
A practical guide for calculating indirect costs of disease
Koopmanschap, M. A., & Rutten, F. F. H. (1996) · PharmacoEconomics · doi:10.2165/00019053-199610050-00003 · Cited by 358 · see citing works
Cost-of-illness studies of depression
Luppa, M., Heinrich, S., Angermeyer, M. C., König, H., & Riedel-Heller, S. G. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.017 · Cited by 356 · see citing works
An outcome study of psychotherapy for patients with borderline personality disorder.
(1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.3.358 · Cited by 328 · see citing works
Labor and Health Status in Economic Evaluation of Health Care: The Health and Labor Questionnaire
Roijen, L. H., Essink‐Bot, M., Koopmanschap, M., Bonsel, G. J., & Rutten, F. (1996) · International Journal of Technology Assessment in Health Care · doi:10.1017/s0266462300009764 · Cited by 303 · see citing works
Treatment histories of borderline inpatients
Zanarini, M. C., Frankenburg, F. R., Khera, G. S., & Bleichmar, J. (2001) · Comprehensive Psychiatry · doi:10.1053/comp.2001.19749 · Cited by 290 · see citing works
Lost productivity among full‐time workers with mental disorders
Lim, D., Sanderson, K. A., & Andrews, G. (2000) · The Journal of Mental Health Policy and Economics · doi:10.1002/mhp.93 · Cited by 266 · see citing works
The Burden of Disease in Personality Disorders: Diagnosis-Specific Quality of Life
Soeteman, D. I., Verheul, R., & Busschbach, J. J. V. (2008) · Journal of Personality Disorders · doi:10.1521/pedi.2008.22.3.259 · Cited by 218 · see citing works
Self-citationBATEMAN, A. W., & Fonagy, P. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.1.169 · Cited by 209 · see citing works
Treatment Rejecting and Treatment Seeking Personality Disorders: Type R and Type S
Tyrer, P., Mitchard, S., Methuen, C., & Ranger, M. (2003) · Journal of Personality Disorders · doi:10.1521/pedi.17.3.263.22152 · Cited by 195 · see citing works
Growth of the Literature on the Topic of Personality Disorders
Blashfield, R. K., & Intoccia, V. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.3.472 · Cited by 185 · see citing works
The economic impact of schizophrenia.
Rice, D. P. (1999) · PubMed · Cited by 183 · see citing works
Indirect Costs in Economic Studies
Koopmanschap, M. A., & Rutten, F. (1993) · PharmacoEconomics · doi:10.2165/00019053-199304060-00006 · Cited by 170 · see citing works
The economic burden of depression in the US: societal and patient perspectives
Greenberg, P. E., & Birnbaum, H. G. (2005) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.6.3.369 · Cited by 166 · see citing works
Frequent consulters in general practice
Gill, D. M., & Sharpe, M. (1999) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(98)00118-4 · Cited by 141 · see citing works
Goeree, R. A., OʼBrien, B. J., Blackhouse, G., Agro, K., & Goering, P. N. (1999) · The Canadian Journal of Psychiatry · doi:10.1177/070674379904400505 · Cited by 90 · see citing works
Economic impact of personality disorders in UK primary care attenders
Rendu, A., Moran, P., Patel, A. K., Knapp, M. R. J., & MANN, A. H. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.181.1.62 · Cited by 83 · see citing works
Verstappen, S. M. M., Boonen, A. E. R. C. H., Verkleij, H., Bijlsma, J. W. J., Buskens, E., & Jacobs, J. W. G. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.033977 · Cited by 81 · see citing works
The cost-effectiveness of psychotherapy: a plan for research
KRUPNICK, J. L., & Pincus, H. A. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.10.1295 · Cited by 69 · see citing works
Cost-offset following specialist treatment of severe personality disorders
Dolan, B. M., Warren, F., Menzies, D., & Norton, K. (1996) · Psychiatric Bulletin · doi:10.1192/pb.20.7.413 · Cited by 57 · see citing works
Schizophrenia, substance use disorders and medical co-morbidity
Dickey, B., Azeni, H., Weiss, R. D., & Sederer, L. I. (2000) · The Journal of Mental Health Policy and Economics · doi:10.1002/1099-176x(200003)3:1 · Cited by 41 · see citing works
Economic outcomes and costs in the treatment of schizophrenia
Knapp, M. R. J. (1997) · Clinical Therapeutics · doi:10.1016/s0149-2918(97)80080-x · Cited by 38 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Cost of disorders of the brain in Europe 2010
Gustavsson, A., Svensson, M., Jacobi, F., Allgulander, C., Alonso, J., Beghi, E., Dodel, R., Ekman, M., Faravelli, C., Fratiglioni, L., et al. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.08.008 · Cited by 1,723 · see citing works
Bamelis, L. L. M., Evers, S. M. A. A., Spinhoven, P., & Arntz, A. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12040518 · Cited by 497 · see citing works
Psychological therapies for people with borderline personality disorder
Storebø, O. J., Stoffers-Winterling, J. M., Völlm, B. A., Kongerslev, M. T., Mattivi, J. T., Jørgensen, M. S., Faltinsen, E., Todorovac, A., Sales, C. P., Callesen, H. E., et al. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012955.pub2 · Cited by 450 · see citing works
Personality Disorders in DSM-5
Skodol, A. E. (2012) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032511-143131 · Cited by 360 · see citing works
Skodol, A. E., Clark, L. A., Bender, D. S., Krueger, R. F., Morey, L. C., Verheul, R., Alarcon, R. D., Bell, C. C., Siever, L. J., & Oldham, J. M. (2011) · Personality Disorders: Theory, Research, and Treatment · doi:10.1037/a0021891 · Cited by 305 · see citing works
Self-citationRizvi, S. L., Dimeff, L. A., Skutch, J., Carroll, D., & Linehan, M. M. (2011) · Behavior Therapy · doi:10.1016/j.beth.2011.01.003 · Cited by 271 · see citing works
Friborg, O., Martinsen, E. W., Martinussen, M., Kaiser, S., Øvergård, K. T., & Rosenvinge, J. H. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.08.023 · Cited by 242 · see citing works
Personality Disorder Types Proposed for DSM-5
Skodol, A. E., Bender, D. S., Morey, L. C., Clark, L. A., Oldham, J. M., Alarcon, R. D., Krueger, R. F., Verheul, R., Bell, C. C., & Siever, L. J. (2011) · Journal of Personality Disorders · doi:10.1521/pedi.2011.25.2.136 · Cited by 241 · see citing works
Self-citationBales, D., van Beek, N., Smits, M., Willemsen, S., Busschbach, J. J. V., Verheul, R., & Andrea, H. (2012) · Journal of Personality Disorders · doi:10.1521/pedi.2012.26.4.568 · Cited by 199 · see citing works
Self-citationPinto, A., Steinglass, J. E., Greene, A. L., Weber, E. U., & Simpson, H. B. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.09.007 · Cited by 169 · see citing works
Treatment of Borderline Personality Disorder: Is Supply Adequate to Meet Public Health Needs?
Iliakis, E. A., Sonley, A. K. I., Ilagan, G. S., & Choi-Kain, L. W. (2019) · Psychiatric Services · doi:10.1176/appi.ps.201900073 · Cited by 161 · see citing works
Atroszko, P. A., Demetrovics, Z., & Griffiths, M. D. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17020660 · Cited by 138 · see citing works
Personality disorder: a new global perspective
TYRER, P., MULDER, R., CRAWFORD, M., NEWTON-HOWES, G., SIMONSEN, E., NDETEI, D., KOLDOBSKY, N., FOSSATI, A., MBATIA, J., & BARRETT, B. (2010) · World Psychiatry · doi:10.1002/j.2051-5545.2010.tb00270.x · Cited by 102 · see citing works
Wagner, T., Fydrich, T., Stiglmayr, C., Marschall, P., Salize, H.-J., Renneberg, B., Fleßa, S., & Roepke, S. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.07.004 · Cited by 92 · see citing works
McMain, S. F., Chapman, A. L., Kuo, J. R., Guimond, T., Streiner, D. L., Dixon-Gordon, K. L., Isaranuwatchai, W., & Hoch, J. S. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1802-z · Cited by 82 · see citing works
Personality disorders are important risk factors for disability pensioning
Østby, K. A., Czajkowski, N., Knudsen, G. P., Ystrom, E., Gjerde, L. C., Kendler, K. S., Ørstavik, R. E., & Reichborn-Kjennerud, T. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0878-0 · Cited by 72 · see citing works
Schramm, A. T., Venta, A., & Sharp, C. (2013) · Personality Disorders: Theory, Research, and Treatment · doi:10.1037/a0031389 · Cited by 55 · see citing works
Prada, P., Zamberg, I., Bouillault, G., Jimenez, N., Zimmermann, J., Hasler, R., Aubry, J.-M., Nicastro, R., & Perroud, N. (2017) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12178 · Cited by 47 · see citing works
Slotema, C. W., Blom, J. D., Niemantsverdriet, M. B. A., Deen, M., & Sommer, I. E. C. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00084 · Cited by 46 · see citing works
Hastrup, L. H., Kongerslev, M. T., & Simonsen, E. (2019) · Journal of Personality Disorders · doi:10.1521/pedi_2018_32_344 · Cited by 44 · see citing works
Bamelis, L. L. M., Arntz, A., Wetzelaer, P., Verdoorn, R., & Evers, S. M. A. A. (2015) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09412 · Cited by 35 · see citing works
Bamelis, L. L., Evers, S. M., & Arntz, A. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-75 · Cited by 33 · see citing works
Eye movement desensitization and reprocessing (EMDR) in patients with a personality disorder
Hafkemeijer, L., de Jongh, A., van der Palen, J., & Starrenburg, A. (2020) · European Journal of Psychotraumatology · doi:10.1080/20008198.2020.1838777 · Cited by 26 · see citing works
Schilling, L., Moritz, S., Köther, U., & Nagel, M. (2015) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.29.2.153 · Cited by 24 · see citing works
Gjerde, L. C., Czajkowski, N., Røysamb, E., Ystrom, E., Tambs, K., Aggen, S. H., Ørstavik, R. E., Kendler, K. S., Reichborn-Kjennerud, T., & Knudsen, G. P. (2015) · Psychological Medicine · doi:10.1017/s0033291715001440 · Cited by 23 · see citing works
Personality disorder and population mental health
Quirk, S. E., Williams, L. J., Chanen, A. M., & Berk, M. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00144-8 · Cited by 21 · see citing works
Groot, I. Z., Venhuizen, A.-S. S. M., Bachrach, N., Walhout, S., de Moor, B., Nikkels, K., Dalmeijer, S., Maarschalkerweerd, M., van Aalderen, J. R., de Lange, H., et al. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04248-9 · Cited by 18 · see citing works
Gharraee, B., Shabani, A., Masoumian, S., Zamirinejad, S., Yaghmaeezadeh, H., Khanjani, S., & Ghahremani, S. (2021) · doi:10.21203/rs.3.rs-670472/v1 · Cited by 9 · see citing works
Mindfulness and negative affectivity in real time: a within-person process model
Mneimne, M., Dashineau, S., & Yoon, K. L. (2019) · Cognition and Emotion · doi:10.1080/02699931.2019.1597684 · Cited by 7 · see citing works
Tijdig herkennen en behandelen van borderlineproblematiek bij jongeren met MBT-early
Hutsebaut, J., Feenstra, D., Keur, E., Schäfer, B., & Bales, D. (2017) · Tijdschrift voor Psychotherapie · doi:10.1007/s12485-017-0216-6 · Cited by 5 · see citing works
Suñol, J., María Panisello, J., Castell, E., Juan Tárraga López, P., Sánchez, C., & Pérez, V. (2017) · Universal Journal of Public Health · doi:10.13189/ujph.2017.050305 · Cited by 4 · see citing works
Remeeus, M. G. A., Clarke, S. L., Feenstra, D. J., Van Eeren, H., Smits, M. L., Debruyne, S., Kouijzer, M. E. J., Luyten, P., Scholte, R. H. J., & Hutsebaut, J. (2024) · Trials · doi:10.1186/s13063-024-08095-9 · Cited by 3 · see citing works
“In addition, people with BPD often have poor physical health [3] and excess mortality from medical conditions [1] resulting in a high burden of disease and considerable societal costs [7, 8].”
Mason, C. K., Kelley, K., & DeShong, H. L. (2024) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2023.100693
- Authors
- Soeteman, D. I., Hakkaart-van Roijen, L., Verheul, R., & Busschbach, J. J. V.
- Affiliations
- De Viersprong (NL)
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2008-02-15
- Volume
- 69
- Issue
- 2
- Pages
- 259-265
- ISSN
- 0160-6689 (ISSN-L)
- OpenAlex
- W2142467951
- Cited by
- 417
- References
- 26
- Citations by year
- 2026: 10 · 2025: 23 · 2024: 17 · 2023: 68 · 2022: 35 · 2021: 41 · 2020: 24 · 2019: 25 · 2018: 25 · 2017: 22 · 2016: 16 · 2015: 24 · 2014: 17 · 2013: 17 · 2012: 15
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- UvA-DARE (University of Amsterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- personality disorders, economic burden, direct medical costs, indirect costs, productivity loss, borderline personality disorder, obsessive-compulsive personality disorder, DSM-IV personality disorders, mental health care costs, treatment-seeking patients, health care reimbursement
- MeSH terms
- Adult, Aged, Analysis of Variance, Female, Humans, Male, Mental Health Services, Middle Aged, Netherlands, Personality Disorders, Surveys and Questionnaires, Regression Analysis, Health Care Costs, Cost of Illness
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