The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Estrogenic control of mitochondrial function and biogenesis
Open accessAbstract
Estrogens have cell‐specific effects on a variety of physiological endpoints including regulation of mitochondrial biogenesis and activity. Estrogens regulate gene transcription by the classical genomic mechanism of binding to estrogen receptors α and β (ERα and ERβ) as well as the more recently described nongenomic pathways involving plasma membrane‐associated ERs that activate intracellular protein kinase‐mediated phosphorylation signaling cascades. Here I will review the rapid and longer‐term effects of estrogen on mitochondrial function. The identification of ERα and ERβ within mitochondria of various cells and tissues is discussed with a model of estrogen regulation of the transcription of nuclear respiratory factor‐1 (NRF‐1, NRF1). NRF‐1 subsequently promotes transcription of mitochondrial transcription factor Tfam (mtDNA maintenance factor, also called mtTFA) and then Tfam targets mtDNA‐encoded genes. The nuclear effects of estrogens on gene expression directly controlling mitochondrial biogenesis, oxygen consumption, mtDNA transcription, and apoptosis are reviewed. Overall, we are just beginning to evaluate the many direct and indirect effects of estrogens on mitochondrial activities. J. Cell. Biochem. 105: 1342–1351, 2008. © 2008 Wiley‐Liss, Inc.
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Citations
Cites
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
Ventura-Clapier, R., Garnier, A., & Veksler, V. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn098 · Cited by 932
Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?
Guarente, L. (2008) · Cell · doi:10.1016/j.cell.2008.01.007 · Cited by 513
Nuclear control of respiratory gene expression in mammalian cells
Scarpulla, R. C. (2006) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20743 · Cited by 489
Estrogen Increases Mitochondrial Efficiency and Reduces Oxidative Stress in Cerebral Blood Vessels
Stirone, C., Duckles, S. P., Krause, D. N., & Procaccio, V. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.014662 · Cited by 315
Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria
Irwin, R. W., Yao, J., Hamilton, R. T., Cadenas, E., Brinton, R. D., & Nilsen, J. (2008) · Endocrinology · doi:10.1210/en.2007-1227 · Cited by 289
Mitochondrial localization of ERα and ERβ in human MCF7 cells
Chen, J. Q., Delannoy, M., Cooke, C., & Yager, J. D. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00508.2003 · Cited by 272
Viña, J., Borrás, C., Gambini, J., Sastre, J., & Pallardó, F. V. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.03.090 · Cited by 271
Rapid Estrogen Signaling in the Brain
Raz, L., Khan, M. M., Mahesh, V. B., Vadlamudi, R. K., & Brann, D. W. (2008) · Neurosignals · doi:10.1159/000111559 · Cited by 201
Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor α in Brain Endothelial Cells
Razmara, A., Sunday, L., Stirone, C., Wang, X. B., Krause, D. N., Duckles, S. P., & Procaccio, V. (2008) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.134072 · Cited by 161
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Iorga, A., Cunningham, C. M., Moazeni, S., Ruffenach, G., Umar, S., & Eghbali, M. (2017) · Biology of Sex Differences · doi:10.1186/s13293-017-0152-8 · Cited by 914
Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
Cheng, A., Wan, R., Yang, J.-L., Kamimura, N., Son, T. G., Ouyang, X., Luo, Y., Okun, E., & Mattson, M. P. (2012) · Nature Communications · doi:10.1038/ncomms2238 · Cited by 401
Mitochondria: A central target for sex differences in pathologies
Ventura-Clapier, R., Moulin, M., Piquereau, J., Lemaire, C., Mericskay, M., Veksler, V., & Garnier, A. (2017) · Clinical Science · doi:10.1042/cs20160485 · Cited by 371
Signaling the mitochondrial unfolded protein response
Pellegrino, M. W., Nargund, A. M., & Haynes, C. M. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.02.019 · Cited by 359
Telonis, A. G., Loher, P., Honda, S., Jing, Y., Palazzo, J., Kirino, Y., & Rigoutsos, I. (2015) · Oncotarget · doi:10.18632/oncotarget.4695 · Cited by 191
Metadata
- Authors
- Klinge, C. M.
- Venue
- Journal of Cellular Biochemistry
- Publisher
- Wiley
- Published
- 2008-10-07
- Volume
- 105
- Issue
- 6
- Pages
- 1342-1351
- ISSN
- 0730-2312 (ISSN-L)
- 1097-4644
- OpenAlex
- W2046082610
- Cited by
- 318
- References
- 9
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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