Rapid Estrogen Signaling in the Brain

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

Revankar, C. M., Cimino, D. F., Sklar, L. A., Arterburn, J. B., & Prossnitz, E. R. (2005) · Science · doi:10.1126/science.1106943 · Cited by 2,302 · see citing works

Estrogen Actions in the Central Nervous System

McEwen, B. S., & Alves, S. E. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0365 · Cited by 1,483 · see citing works

Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

Thomas, P., Pang, Y., Filardo, E. J., & Dong, J. (2004) · Endocrinology · doi:10.1210/en.2004-1064 · Cited by 1,410 · see citing works

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Filardo, E. J., Quinn, J. A., Bland, K. I., & Frackelton, A. R. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.10.0532 · Cited by 1,387 · see citing works

The Multifaceted Mechanisms of Estradiol and Estrogen Receptor Signaling

Hall, J. M., Couse, J. F., & Korach, K. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100029200 · Cited by 1,202 · see citing works

Skeletal Effects of Estrogen*

Turner, R. T., Riggs, B. L., & Spelsberg, T. C. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-3-275 · Cited by 758 · see citing works

Integration of the extranuclear and nuclear actions of estrogen

Levin, E. R. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0390 · Cited by 708 · see citing works

Neurotrophic and neuroprotective actions of estrogen: Basic mechanisms and clinical implications

Brann, D. W., Dhandapani, K. M., Wakade, C. G., Mahesh, V. B., & Khan, M. M. (2007) · Steroids · doi:10.1016/j.steroids.2007.02.003 · Cited by 649 · see citing works

A novel signaling molecule, p130, forms stable complexes in vivo with v‐Crk and v‐Src in a tyrosine phosphorylation‐dependent manner.

Sakai, R., Iwamatsu, A., Hirano, N., Ogawa, S., Tanaka, T., Mano, H., Yazaki, Y., & Hirai, H. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06684.x · Cited by 648 · see citing works

Estrogen Actions in the Central Nervous System

McEwen, B. S. (1999) · Endocrine Reviews · doi:10.1210/er.20.3.279 · Cited by 640 · see citing works

Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor

Mermelstein, P. G., Becker, J., & Surmeier, D. J. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00595.1996 · Cited by 633 · see citing works

Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer

Carmeci, C., Thompson, D. A., Ring, H. Z., Francke, U., & Weigel, R. J. (1997) · Genomics · doi:10.1006/geno.1997.4972 · Cited by 590 · see citing works

Estrogen and cognitive functioning in women

Sherwin, B. B. (2003) · Endocrine Reviews · doi:10.1210/er.2001-0016 · Cited by 560 · see citing works

ER-X: A Novel, Plasma Membrane-Associated, Putative Estrogen Receptor That Is Regulated during Development and after Ischemic Brain Injury

Toran‐Allerand, C. D., Guan, X., MacLusky, N. J., Horváth, T. L., Diano, S., Singh, M., Connolly, E. S., Nethrapalli, I. S., & Tinnikov, A. A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-19-08391.2002 · Cited by 547 · see citing works

Nature of Functional Estrogen Receptors at the Plasma Membrane

Pedram, A., Razandi, M., & Levin, E. R. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0525 · Cited by 523 · see citing works

Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system

Brailoiu, E., Dun, S. L., Brailoiu, G. C., Mizuo, K., Sklar, L. A., Oprea, T. I., Prossnitz, E. R., & Dun, N. J. (2007) · Journal of Endocrinology · doi:10.1677/joe-07-0017 · Cited by 501 · see citing works

Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites

Milner, T. A., McEwen, B. S., Hayashi, S., Li, C. J., Reagan, L. P., & Alves, S. E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20010115)429:3 · Cited by 491 · see citing works

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

Watters, J. J., Campbell, J. S., Cunningham, M. J., Krebs, E. G., & Dorsa, D. M. (1997) · Endocrinology · doi:10.1210/endo.138.9.5489 · Cited by 490 · see citing works

Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways

Singh, M., Sétáló, G., Guan, X., Warren, M., & Toran‐Allerand, C. D. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-04-01179.1999 · Cited by 465 · see citing works

Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C

Qiu, J., Bosch, M. A., Tobias, S. C., Grandy, D. K., Scanlan, T. S., Rønnekleiv, O. K., & Kelly, M. J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-29-09529.2003 · Cited by 460 · see citing works

Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons

Wong, M., & Moss, R. L. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-08-03217.1992 · Cited by 455 · see citing works

A Conserved Mechanism for Steroid Receptor Translocation to the Plasma Membrane

Pedram, A., Razandi, M., Sainson, R. C. A., Kim, J. K., Hughes, C. C. W., & Levin, E. R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611877200 · Cited by 449 · see citing works

Palmitoylation-dependent Estrogen Receptor α Membrane Localization: Regulation by 17β-Estradiol

Acconcia, F., Ascenzi, P., Bocedi, A., Spisni, E., Tomasi, V., Trentalance, A., Visca, P., & Marino, M. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-07-0547 · Cited by 440 · see citing works

Genomic Targets of Nuclear Estrogen Receptors

O’Lone, R. B., Frith, M. C., Karlsson, E. K., & Hansen, U. M. (2004) · Molecular Endocrinology · doi:10.1210/me.2003-0044 · Cited by 439 · see citing works

Induction of p130 cas Signaling Complex Formation upon Integrin-Mediated Cell Adhesion: a Role for Src Family Kinases

Vuori, K., Hirai, H., Aizawa, S., & Ruoslahti, E. I. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.6.2606 · Cited by 421 · see citing works

ERs Associate with and Regulate the Production of Caveolin: Implications for Signaling and Cellular Actions

Razandi, M., Oh, P., Pedram, A., Schnitzer, J. E., & Levin, E. R. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.1.0757 · Cited by 402 · see citing works

GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release

Filardo, E. J., & Thomas, P. (2005) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2005.08.005 · Cited by 388 · see citing works

Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation

Milner, T. A., Ayoola, K., Drake, C. T., Herrick, S. P., Tabori, N. E., McEwen, B. S., Mitra, S. W., & Alves, S. E. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20724 · Cited by 358 · see citing works

G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane

Funakoshi, T., Yanai, A., Shinoda, K., Kawano, M. M., & Mizukami, Y. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.191 · Cited by 352 · see citing works

17β-Estradiol Potentiates Kainate-Induced Currents via Activation of the cAMP Cascade

Gu, Q., & Moss, R. L. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-11-03620.1996 · Cited by 346 · see citing works

Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor α

Lu, Q. R., Pallas, D. C., Surks, H. K., Baur, W. E., Mendelsohn, M. E., & Karas, R. H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407492101 · Cited by 266 · see citing works

Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons

Nabekura, J., Oomura, Y., Minami, T., Mizuno, Y., & Fukuda, A. (1986) · Science · doi:10.1126/science.3726531 · Cited by 262 · see citing works

Emerging diversities in the mechanism of action of steroid hormones

Brann, D. W., Hendry, L. B., & Mahesh, V. B. (1995) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(94)00160-n · Cited by 260 · see citing works

ICAM-1 Signaling Pathways Associated with Rho Activation in Microvascular Brain Endothelial Cells

Etienne‐Manneville, S., Adamson, P., Greenwood, J., Strosberg, A. D., Cazaubon, S. M., & Couraud, P. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.10.5755 · Cited by 248 · see citing works

Estrogen-Induced Activation of the Mitogen-Activated Protein Kinase Cascade in the Cerebral Cortex of Estrogen Receptor-α Knock-Out Mice

Singh, M., Sétáló, G., Guan, X., Frail, D. E., & Toran‐Allerand, C. D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-05-01694.2000 · Cited by 247 · see citing works

Estrogen Dendrimer Conjugates that Preferentially Activate Extranuclear, Nongenomic Versus Genomic Pathways of Estrogen Action

Harrington, W. R., Kim, S. H., Funk, C. C., Madak‐Erdogan, Z., Schiff, R., Katzenellenbogen, J. A., & Katzenellenbogen, B. S. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0186 · Cited by 246 · see citing works

Skeletal effects of estrogen

Turner, R. T. (1994) · Endocrine Reviews · doi:10.1210/er.15.3.275 · Cited by 242 · see citing works

Membrane-Initiated Actions of Estrogens in Neuroendocrinology: Emerging Principles

Vasudevan, N., & Pfaff, D. W. (2007) · Endocrine Reviews · doi:10.1210/er.2005-0021 · Cited by 231 · see citing works

Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways

Kelly, M. J. (1999) · Steroids · doi:10.1016/s0039-128x(98)00095-6 · Cited by 227 · see citing works

17β-estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuroprotection

Wu, T.-W., Wang, J. M., Chen, S., & Brinton, R. D. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.027 · Cited by 227 · see citing works

Steering estrogen signals from the plasma membrane to the nucleus: Two sides of the coin

Manavathi, B., & Kumar, R. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20551 · Cited by 222 · see citing works

Protective Effects of Estrogen and Selective Estrogen Receptor Modulators in the Brain1

Dhandapani, K. M., & Brann, D. W. (2002) · Biology of Reproduction · doi:10.1095/biolreprod.102.003848 · Cited by 218 · see citing works

Estrogen-containing hormone therapy and Alzheimer’s disease risk: Understanding discrepant inferences from observational and experimental research

Henderson, V. W. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.06.017 · Cited by 215 · see citing works

Rapid modulation of long‐term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons

Mukai, H., Tsurugizawa, T., Murakami, G., Kominami, S., Ishii, H., Ogiue-Ikeda, M., Takata, N., Tanabe, N., Furukawa, A., Hojo, Y., et al. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04264.x · Cited by 214 · see citing works

Estrogen Receptor Protein Interaction with Phosphatidylinositol 3-Kinase Leads to Activation of Phosphorylated Akt and Extracellular Signal-Regulated Kinase 1/2 in the Same Population of Cortical Neurons: A Unified Mechanism of Estrogen Action

Mannella, P., & Brinton, R. D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1443-06.2006 · Cited by 213 · see citing works

Estrogen Receptor β Mediates Rapid Estrogen Actions on Gonadotropin-Releasing Hormone NeuronsIn Vivo

Ábrahám, I. M., Han, S., Todman, M. G., Korach, K. S., & Herbison, A. E. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-13-05771.2003 · Cited by 212 · see citing works

Estrogen Receptor-Mediated Rapid Signaling

Moriarty, K., Kim, K. H., & Bender, J. R. (2006) · Endocrinology · doi:10.1210/en.2006-0729 · Cited by 205 · see citing works

Direct and Indirect Regulation of Gonadotropin-Releasing Hormone Neurons by Estradiol1

Petersen, S. L., Ottem, E. N., & Carpenter, C. D. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.103.019745 · Cited by 201 · see citing works

Nonclassical estrogen receptor α signaling mediates negative feedback in the female mouse reproductive axis

Glidewell-Kenney, C., Hurley, L., Pfaff, L. E., Weiss, J., Levine, J. E., & Jameson, J. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611514104 · Cited by 200 · see citing works

Differential Effects of Estradiol and Estradiol-BSA Conjugates

Stevis, P. E., Deecher, D. C., Suhadolnik, L., Mallis, L. M., & Frail, D. E. (1999) · Endocrinology · doi:10.1210/endo.140.11.7247 · Cited by 197 · see citing works

Critical in Vivo Roles for Classical Estrogen Receptors in Rapid Estrogen Actions on Intracellular Signaling in Mouse Brain

Ábrahám, I. M., Todman, M. G., Korach, K. S., & Herbison, A. E. (2004) · Endocrinology · doi:10.1210/en.2003-1676 · Cited by 197 · see citing works

Molecular Cloning and Characterization of PELP1, a Novel Human Coregulator of Estrogen Receptor α

Vadlamudi, R. K., Wang, R., Mazumdar, A., Şahin, A. A., Kumar, R., Kim, Y.-S., & Shin, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103783200 · Cited by 193 · see citing works

The effects of microelectrophoretically applied estrogen, cortisol and acetylcholine on medial preoptic-septal unit activity throughout the estrous cycle of the female rat

Kelly, M. J., Moss, R. L., & Dudley, C. A. (1977) · Experimental Brain Research · doi:10.1007/bf00237858 · Cited by 185 · see citing works

S-palmitoylation modulates human estrogen receptor-α functions

Acconcia, F., Ascenzi, P., Fabozzi, G., Visca, P., & Marino, M. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.02.129 · Cited by 180 · see citing works

Receptor Mechanisms Mediating Non-Genomic Actions of Sex Steroids

Boonyaratanakornkit, V., & Edwards, D. (2007) · Seminars in Reproductive Medicine · doi:10.1055/s-2007-973427 · Cited by 178 · see citing works

The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actions

Kow, L., & Pfaff, D. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404889101 · Cited by 171 · see citing works

Differential sensitivity of preoptic-septal neurons to microelectrophoressed estrogen during the estrous cycle

Kelly, M. J., Moss, R. L., & Dudley, C. A. (1976) · Brain Research · doi:10.1016/0006-8993(76)91017-9 · Cited by 170 · see citing works

Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line

Vasudevan, N., Kow, L., & Pfaff, D. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.221449798 · Cited by 159 · see citing works

Single unit recording in hypothalamus and preoptic area of estrogen-treated and untreated ovariectomized female rats

Bueno, J., & Pfaff, D. W. (1976) · Brain Research · doi:10.1016/0006-8993(76)90988-4 · Cited by 157 · see citing works

Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores

Beyer, C., & Raab, H. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00045.x · Cited by 138 · see citing works

The specificity of the response of preoptic-septal area neurons to estrogen: 17?-estradiol versus 17?-estradiol and the response of extrahypothalamic neurons

Kelly, M. J., Moss, R. L., Dudley, C. A., & Fawcett, C. P. (1977) · Experimental Brain Research · doi:10.1007/bf00237857 · Cited by 137 · see citing works

Estradiol Stimulates Progesterone Synthesis in Hypothalamic Astrocyte Cultures

Micevych, P. E., Chaban, V. V., Ogi, J., Dewing, P., Lu, J. K. H., & Sinchak, K. (2006) · Endocrinology · doi:10.1210/en.2006-0774 · Cited by 136 · see citing works

MAPK Signaling Is Critical to Estradiol Protection of CA1 Neurons in Global Ischemia

Jover‐Mengual, T., Zukin, R. S., & Etgen, A. M. (2006) · Endocrinology · doi:10.1210/en.2006-1137 · Cited by 131 · see citing works

17β-estradiol induces Ca2+ influx, dendritic and nuclear Ca2+ rise and subsequent cyclic AMP response element-binding protein activation in hippocampal neurons: A potential initiation mechanism for estrogen neurotrophism

Zhao, L.-Q., Chen, S.-H., Wang, M. J., & Brinton, R. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.11.054 · Cited by 129 · see citing works

A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons

Castets, F., Bartoli, M., Barnier, J. V., Baillat, G., Salin, P., Moqrich, A., Bourgeois, J. P., Denizot, F., Rougon, G., Calothy, G., et al. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.134.4.1051 · Cited by 129 · see citing works

p130Cas interacts with estrogen receptor α and modulates non-genomic estrogen signaling in breast cancer cells

Cabodi, S., Moro, L., Baj, G., Smeriglio, M., Stefano, P. D., Gippone, S., Surico, N., Silengo, L., Turco, E., Tarone, G., et al. (2004) · Journal of Cell Science · doi:10.1242/jcs.01025 · Cited by 128 · see citing works

Zinedin, SG2NA, and Striatin Are Calmodulin-binding, WD Repeat Proteins Principally Expressed in the Brain

Castets, F., Rakitina, T. V., Gaillard, S., Moqrich, A., Mattéi, M., & Monneron, A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909782199 · Cited by 127 · see citing works

Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons

Honda, K., Shimohama, S., Sawada, H., Kihara, T., Nakamizo, T., Shibasaki, H., & Akaike, A. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1098 · Cited by 126 · see citing works

Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus

Kuroki, Y., Fukushima, K., Kanda, Y., Mizuno, K., & Watanabe, Y. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00425-8 · Cited by 126 · see citing works

Estrogen induces a rapid secretion of amyloid β precursor protein via the mitogen‐activated protein kinase pathway

Manthey, D., Heck, S., Engert, S., & Behl, C. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02346.x · Cited by 122 · see citing works

Estrogen Modulation of G‐Protein‐Coupled Receptor Activation of Potassium Channels in the Central Nervous System

Kelly, M. J., Qiu, J., & Rønnekleiv, O. K. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1286.001 · Cited by 121 · see citing works

Changes in firing rates of single preoptic and hypothalamic units following an intravenous administration of estrogen in the castrated female rat

Yagi, K. (1973) · Brain Research · doi:10.1016/0006-8993(73)90219-9 · Cited by 116 · see citing works

Sex Differences in Hippocampal Estradiol-Induced N-Methyl-D-Aspartic Acid Binding and Ultrastructural Localization of Estrogen Receptor-Alpha

Romeo, R. D., McCarthy, J. B., Wang, A. C., Milner, T. A., & McEwen, B. S. (2005) · Neuroendocrinology · doi:10.1159/000089557 · Cited by 115 · see citing works

Diversity of ovarian steroid signaling in the hypothalamus.

Rønnekleiv, O., & Kelly, M. J. (2005) · Frontiers in neuroendocrinology (Print) · doi:10.1016/j.yfrne.2005.05.001 · Cited by 109 · see citing works

Requirements for estrogen receptor α membrane localization and function

Evinger, A. J., & Levin, E. (2005) · Steroids · doi:10.1016/j.steroids.2005.02.015 · Cited by 108 · see citing works

Estrogen as Neuroprotectant of Nigrostriatal Dopaminergic System: Laboratory and Clinical Studies

Dluzen, D. E., & Horstink, M. W. I. M. (2003) · Endocrine · doi:10.1385/endo:21:1:67 · Cited by 106 · see citing works

Caveolin-1 Mutations in Human Breast Cancer

Li, T., Sotgia, F., Vuolo, M. A., Li, M., Yang, W., Pestell, R. G., Sparano, J. A., & Lisanti, M. P. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.051089 · Cited by 105 · see citing works

The striatin family: A new signaling platform in dendritic spines

Benoist, M., Gaillard, S., & Castets, F. (2006) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2005.12.006 · Cited by 104 · see citing works

Neuroprotection by estrogen via extracellular signal‐regulated kinase against quinolinic acid‐induced cell death in the rat hippocampus

Kuroki, Y., Fukushima, K., Kanda, Y., Mizuno, K., & Watanabe, Y. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01409.x · Cited by 98 · see citing works

Estrogen activates rapid signaling in the brain: Role of estrogen receptor α and estrogen receptor β in neurons and glia

Mhyre, A. J., & Dorsa, D. M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.10.019 · Cited by 97 · see citing works

Regulation of Cyclic Adenosine 3′,5′-Monophosphate Signaling and Pulsatile Neurosecretion by Gi-coupled Plasma Membrane Estrogen Receptors in Immortalized Gonadotropin-Releasing Hormone Neurons

Navarro, C. E., Saeed, S. A., Murdock, C. M., Martínez‐Fuentes, A. J., Arora, K. K., Krsmanović, L. Z., & Catt, K. J. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0040 · Cited by 93 · see citing works

Estradiol enhances Akt activation in cortical explant cultures following neuronal injury

Wilson, M. E., Liu, Y., & Wise, P. M. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00181-x · Cited by 89 · see citing works

Expression of ?2-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells

Marzolo, M., Rommy von Bernhardi, M., Bu, G., & Inestrosa, N. C. (2000) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(20000501)60:3 · Cited by 87 · see citing works

Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA)

Taguchi, Y., Koslowski, M., & Bodenner, D. (2004) · Nuclear Receptor · doi:10.1186/1478-1336-2-5 · Cited by 82 · see citing works

UNIT ACTIVITY IN THE HYPOTHALAMUS, SEPTUM AND PREOPTIC AREA OF THE RAT: CHARACTERISTICS OF SPONTANEOUS ACTIVITY AND THE EFFECT OF OESTROGEN

LINCOLN, D. W. (1967) · Journal of Endocrinology · doi:10.1677/joe.0.0370177 · Cited by 82 · see citing works

Plasma membrane oestrogen receptor mediates neuroprotection against β‐amyloid toxicity through activation of Raf‐1/MEK/ERK cascade in septal‐derived cholinergic SN56 cells

Guerra, B., Díaz, M. L., Alonso, R., & Marín, R. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02695.x · Cited by 82 · see citing works

Cortical inputs to m2-immunoreactive striatal interneurons in rat and monkey

Thomas, T. M., Smith, Y., Levey, A. I., & Hersch, S. M. (2000) · Synapse · doi:10.1002/1098-2396(20000915)37:4 · Cited by 81 · see citing works

Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR

Vadlamudi, R. K., & Kumar, R. (2007) · Nuclear Receptor Signaling · doi:10.1621/nrs.05004 · Cited by 79 · see citing works

Estrogen receptor-α mediates estradiol attenuation of ATP-induced Ca2+ signaling in mouse dorsal root ganglion neurons

Chaban, V. V., & Micevych, P. E. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20524 · Cited by 78 · see citing works

Effects of Estrogen on the Electrical Activity of Identified and Unidentified Hypothalamic Units

DUFY, B., Partouche, C., Poulain, D., Dufy-Barbe, L., & Vincent, J. D. (2008) · Neuroendocrinology · doi:10.1159/000122610 · Cited by 68 · see citing works

Distinctive Actions of Membrane-Targeted Versus Nuclear Localized Estrogen Receptors in Breast Cancer Cells

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Ack1 Mediates Cdc42-dependent Cell Migration and Signaling to p130Cas

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Untitled work

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Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory

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Extranuclear Estrogen Receptors Mediate the Neuroprotective Effects of Estrogen in the Rat Hippocampus

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Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke

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17-β-Estradiol: A Powerful Modulator of Blood–Brain Barrier BCRP Activity

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Estrogen and Tamoxifen Protect against Mn-Induced Toxicity in Rat Cortical Primary Cultures of Neurons and Astrocytes

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Estrogen Is Renoprotective via a Nonreceptor-dependent Mechanism after Cardiac Arrest In Vivo

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Combinations of Physiologic Estrogens with Xenoestrogens Alter ERK Phosphorylation Profiles in Rat Pituitary Cells

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Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1

Bourque, M., Morissette, M., & Paolo, T. D. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.04.006 · Cited by 56 · see citing works

LIM kinase mediates estrogen action on the actin depolymerization factor Cofilin

Yuen, G. S., McEwen, B. S., & Akama, K. T. (2010) · Brain Research · doi:10.1016/j.brainres.2010.07.067 · Cited by 54 · see citing works

Dissecting natural sensory plasticity: hormones and experience in a maternal context

Miranda, J. A., & Liu, R. C. (2009) · Hearing Research · doi:10.1016/j.heares.2009.04.014 · Cited by 52 · see citing works

Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B

Xu, X., Ye, Y., Li, T., Chen, L., Dong, T., Luo, Q., & Lü, M. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.09.007 · Cited by 51 · see citing works

Oestrogen Signalling and Neuroprotection in Cerebral Ischaemia

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17β-Estradiol-Mediated Neuroprotection and ERK Activation Require a Pertussis Toxin-Sensitive Mechanism Involving GRK2 and β-Arrestin-1

Dominguez, R., Hu, E., Zhou, M., & Baudry, M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0550-09.2009 · Cited by 50 · see citing works

Combination Therapy for Multi-Target Manipulation of Secondary Brain Injury Mechanisms

Somayaji, M. R., Przekwas, A. J., & Gupta, R. K. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170828165711 · Cited by 50 · see citing works

Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system

Tozzi, A., de Iure, A., Tantucci, M., Durante, V., Quiroga‐Varela, A., Giampà, C., Mauro, M. D., Mazzocchetti, P., Costa, C., Filippo, M. D., et al. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00192 · Cited by 49 · see citing works

Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway

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Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats

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Long-Term Potentiation in the Rat Medial Vestibular Nuclei Depends on Locally Synthesized 17β-Estradiol

Grassi, S., Frondaroli, A., Dieni, C. V., Scarduzio, M., & Pettorossi, V. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1697-09.2009 · Cited by 45 · see citing works

Association of the rs3743205 variant of DYX1C1 with dyslexia in Chinese children

Lim, C. K. P., Ho, C. S., Chou, C. H. N., & Waye, M. M. Y. (2011) · Behavioral and Brain Functions · doi:10.1186/1744-9081-7-16 · Cited by 47 · see citing works

PELP1: Structure, biological function and clinical significance

Sareddy, G. R., & Vadlamudi, R. K. (2016) · Gene · doi:10.1016/j.gene.2016.03.017 · Cited by 47 · see citing works

Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion

Yang, X., Guo, Y., He, J., Zhang, F., Sun, X., Yang, S., & Dong, H. (2017) · Oncotarget · doi:10.18632/oncotarget.18313 · Cited by 46 · see citing works

Neuroprotective actions of estradiol and novel estrogen analogs in ischemia: Translational implications

Etgen, A. M., Jover‐Mengual, T., & Zukin, R. S. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.12.005 · Cited by 46 · see citing works

Genistein potentiates activity of the cation channel TRPC5 independently of tyrosine kinases

Wong, C., Huang, Y., & Yao, X. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00636.x · Cited by 47 · see citing works

Neuroactive gonadal drugs for neuroprotection in male and female models of Parkinson's disease

Litim, N., Morissette, M., & Paolo, T. D. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.09.024 · Cited by 45 · see citing works

Cooperation of Genomic and Rapid Nongenomic Actions of Estrogens in Synaptic Plasticity

Lai, Y., Yu, D. S., Zhang, J. H., & Chen, G. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9979-y · Cited by 45 · see citing works

Mechanisms underlying the interactions between rapid estrogenic and BDNF control of synaptic connectivity

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G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane

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Rapid Estradiol Modulation of Neuronal Connectivity and Its Implications for Disease

Srivastava, D. P., & Penzes, P. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00077 · Cited by 44 · see citing works

G protein‐coupled receptor 30 contributes to improved remyelination after cuprizone‐induced demyelination

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The brain cytokine levels are modulated by estrogen following traumatic brain injury: Which estrogen receptor serves as modulator?

Khaksari, M., Abbasloo, E., Dehghan, F., Soltani, Z., & Asadikaram, G. (2015) · International Immunopharmacology · doi:10.1016/j.intimp.2015.05.046 · Cited by 43 · see citing works

Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs

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Effects of 17beta-estradiol on glutamate synaptic transmission and neuronal excitability in the rat medial vestibular nuclei.

Grassi, S., Frondaroli, A., Scarduzio, M., Dutia, M., Dieni, C. V., & Pettorossi, V. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.039 · Cited by 43 · see citing works

Male/female differences in neuroprotection and neuromodulation of brain dopamine

Bourque, M. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00035 · Cited by 40 · see citing works

Distribution and Posttranslational Modification of Synaptic ERα in the Adult Female Rat Hippocampus

Tabatadze, N., Smejkalová, T., & Woolley, C. S. (2012) · Endocrinology · doi:10.1210/en.2012-1870 · Cited by 39 · see citing works

Structural Basis for Ca2+-induced Activation and Dimerization of Estrogen Receptor α by Calmodulin

Zhang, Y., Li, Z., Sacks, D. B., & Ames, J. B. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.334797 · Cited by 38 · see citing works

Modulatory role of androgenic and estrogenic neurosteroids in determining the direction of synaptic plasticity in the CA1 hippocampal region of male rats

Pettorossi, V., Mauro, M. D., Scarduzio, M., Panichi, R., Tozzi, A., Calabresi, P., & Grassi, S. (2013) · Physiological Reports · doi:10.1002/phy2.185 · Cited by 37 · see citing works

Signaling mechanisms involved in the acute effects of estradiol on 5-HT clearance

Benmansour, S., Privratsky, A. A., Adeniji, O. S., & Frazer, A. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571300165x · Cited by 38 · see citing works

Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

Tozzi, A., Durante, V., Manca, P., Mauro, M. D., Blasi, J., Grassi, S., Calabresi, P., Kawato, S., & Pettorossi, V. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00534 · Cited by 31 · see citing works

The foam cell-derived exosomal miRNA Novel-3 drives neuroinflammation and ferroptosis during ischemic stroke

Qin, C., Dong, M., Tang, Y., Chu, Y., Zhou, L., Zhang, H., Yang, S., Zhang, L., Pang, X., Zhu, L., et al. (2024) · Nature Aging · doi:10.1038/s43587-024-00727-8 · Cited by 40 · see citing works

Nuclear receptors in transgenerational epigenetic inheritance

Ozgyin, L., Erdős, E., Bojcsuk, D., & Bálint, B. L. (2015) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2015.02.012 · Cited by 37 · see citing works

Sex steroid hormones as neuroprotective elements in ischemia models

Rubio, A. E. C., Pérez-Álvarez, M. J., Chala, C. L., & Wandosell, F. G. (2018) · Journal of Endocrinology · doi:10.1530/joe-18-0129 · Cited by 37 · see citing works

Proline-, glutamic acid-, and leucine-rich protein 1 mediates estrogen rapid signaling and neuroprotection in the brain

Sareddy, G. R., Zhang, Q., Wang, R., Scott, E. L., Zou, Y., O’Connor, J. C., Chen, Y., Dong, Y., Vadlamudi, R. K., & Brann, D. W. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516729112 · Cited by 36 · see citing works

Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat

Mauro, M. D., Tozzi, A., Calabresi, P., Pettorossi, V., & Grassi, S. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00376 · Cited by 31 · see citing works

Estrogenic biological activity and underlying molecular mechanisms of green tea constituents

Kiyama, R. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.11.014 · Cited by 36 · see citing works

17β‐Estradiol protects Schwann cells against H2O2‐induced cytotoxicity and increases transplanted Schwann cell survival in a cervical hemicontusion spinal cord injury model

Siriphorn, A., Chompoopong, S., & Floyd, C. L. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06770.x · Cited by 35 · see citing works

Estradiol and tamoxifen differentially regulate a plasmalemmal voltage-dependent anion channel involved in amyloid-beta induced neurotoxicity

Herrera, J. L., Fernandez, C., Díaz, M. L., Cury, D., & Marín, R. (2011) · Steroids · doi:10.1016/j.steroids.2011.02.014 · Cited by 34 · see citing works

Signalosomes in the brain: relevance in the development of certain neuropathologies such as Alzheimer’s disease

Marín, R. (2011) · Frontiers in Physiology · doi:10.3389/fphys.2011.00023 · Cited by 34 · see citing works

Reprint of ”GPR30 mediates estrogen rapid signaling and neuroprotection”

Tang, H., Zhang, Q., Yang, L., Dong, Y., Khan, M. M., Yang, F., Brann, D. W., & Wang, R. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.05.005 · Cited by 31 · see citing works

Estrogen Receptor β-Selective Agonists Stimulate Calcium Oscillations in Human and Mouse Embryonic Stem Cell-Derived Neurons

Zhang, L., Blackman, B. E., Schonemann, M. D., Zogovic-Kapsalis, T., Pan, X., Tagliaferri, M. A., Harris, H. A., Cohen, I. V., Pera, R. A. R., Mellon, S. H., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011791 · Cited by 30 · see citing works

Membrane-Initiated Signaling of Estrogen in the Brain

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New insights into estrogen signaling and actions in the brain

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Membrane-Initiated Effects of Estrogen in the Central Nervous System

R∅nnekleiv, O. K., & Kelly, M. J. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00032-2 · Cited by 1 · see citing works

The estrous cycle: its influence on single unit activity in the forebrain

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Rapid Estrogen Signaling in the Brain: Implications for the Fine-Tuning of Neuronal Circuitry

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