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Cited by 295

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression

Open access
Donohoe, Dallas R., Bultman, Scott J.·2012·Journal of Cellular Physiology

Abstract

Diet and energy metabolism affect gene expression, which influences human health and disease. Here, we discuss the role of epigenetics as a mechanistic link between energy metabolism and control of gene expression. A number of key energy metabolites including SAM, acetyl‐CoA, NAD+, and ATP serve as essential co‐factors for many, perhaps most, epigenetic enzymes that regulate DNA methylation, posttranslational histone modifications, and nucleosome position. The relative abundance of these energy metabolites allows a cell to sense its energetic state. And as co‐factors, energy metabolites act as rheostats to modulate the activity of epigenetic enzymes and upregulate/downregulate transcription as appropriate to maintain homeostasis. J. Cell. Physiol. 227: 3169–3177, 2012. © 2012 Wiley Periodicals, Inc.

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Crossref · 10.1002/jcp.24054

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Metadata

Authors
Donohoe, D. R., & Bultman, S. J.
Venue
Journal of Cellular Physiology
Publisher
Wiley
Published
2012-05-17
Volume
227
Issue
9
Pages
3169-3177
ISSN
  • 0021-9541 (ISSN-L)
  • 1097-4652
OpenAlex
W2044984438
Cited by
295
References
53
FWCI
4.53
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression. https://app.cochat.ai/papers/10.1002/jcp.24054
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Donohoe, D. R., & Bultman, S. J. (2012). Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression. Journal of Cellular Physiology. https://doi.org/10.1002/jcp.24054

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.