The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Optimization and validation of a fully‐integrated pulse sequence for modified look‐locker inversion‐recovery (MOLLI) T1 mapping of the heart
Open accessAbstract
Purpose: To optimize and validate a fully‐integrated version of modified Look‐Locker inversion‐recovery (MOLLI) for clinical single‐breathhold cardiac T1 mapping. Materials and Methods: A MOLLI variant allowing direct access to all pulse sequence parameters was implemented on a 1.5T MR system. Varying four critical sequence parameters, MOLLI was performed in eight gadolinium‐doped agarose gel phantoms at different simulated heart rates. T1 values were derived for each variant and compared to nominal T1 values. Based on the results, MOLLI was performed in midcavity short‐axis views of 20 healthy volunteers pre‐ and post‐Gd‐DTPA. Results: In phantoms, a readout flip angle of 35°, minimum TI of 100 msec, TI increment of 80 msec, and use of three pausing heart cycles allowed for most accurate and least heart rate–dependent T1 measurements. Using this pulse sequence scheme in humans, T1 relaxation times in normal myocardium were comparable to data from previous studies, and showed narrow ranges both pre‐ and postcontrast without heart rate dependency. Conclusion: We present an optimized implementation of MOLLI for fast T1 mapping with high spatial resolution, which can be integrated into routine imaging protocols. T1 accuracy is superior to the original set of pulse sequence parameters and heart rate dependency is avoided. J. Magn. Reson. Imaging 2007;26:1081–1086. © 2007 Wiley‐Liss, Inc.
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Cites
Modified Look‐Locker inversion recovery (MOLLI) for high‐resolution T1 mapping of the heart
Messroghli, D. R., Radjenovic, A., Kozerke, S., Higgins, D. M., Sivananthan, M. U., & Ridgway, J. P. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20110 · Cited by 1,349
Self-citationCardiovascular Magnetic Resonance in Cardiac Amyloidosis
Maceira, A. M., Joshi, J., Prasad, S. K., Moon, J. C., Perugini, E., Harding, I., Sheppard, M. N., Poole-Wilson, P. A., Hawkins, P. N., & Pennell, D. J. (2005) · Circulation · doi:10.1161/01.cir.0000152819.97857.9d · Cited by 982
Time Saving in Measurement of NMR and EPR Relaxation Times
Look, D. C., & Locker, D. R. (1970) · Review of Scientific Instruments · doi:10.1063/1.1684482 · Cited by 819
Quantification of T1 values by SNAPSHOT-FLASH NMR imaging
Deichmann, R., & Haase, A. (1992) · Journal of Magnetic Resonance (1969) · doi:10.1016/0022-2364(92)90347-a · Cited by 406
Messroghli, D. R., Plein, S., Higgins, D. M., Walters, K., Jones, T. R., Ridgway, J. P., & Sivananthan, M. U. (2006) · Radiology · doi:10.1148/radiol.2382041903 · Cited by 239
Self-citationMessroghli, D., Bainbridge, G. J., Alfakih, K., Jones, T. R., Plein, S., Ridgway, J. P., & Sivananthan, M. U. (2005) · Radiology · doi:10.1148/radiol.2351040249 · Cited by 73
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Chin, C. W. L., Shah, A. S. V., McAllister, D. A., Joanna Cowell, S., Alam, S., Langrish, J. P., Strachan, F. E., Hunter, A. L., Maria Choy, A., Lang, C. C., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu189 · Cited by 233
Kanagala, P., Cheng, A. S. H., Singh, A., Khan, J. N., Gulsin, G. S., Patel, P., Gupta, P., Arnold, J. R., Squire, I. B., Ng, L. L., et al. (2019) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2018.11.031 · Cited by 126
Metadata
- Authors
- Messroghli, D. R., Greiser, A., Fröhlich, M., Dietz, R., & Schulz‐Menger, J.
- Venue
- Journal of Magnetic Resonance Imaging
- Publisher
- Wiley
- Published
- 2007-09-25
- Volume
- 26
- Issue
- 4
- Pages
- 1081-1086
- ISSN
- 1053-1807 (ISSN-L)
- 1522-2586
- OpenAlex
- W2054186815
- Cited by
- 353
- References
- 6
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Messroghli, D. R., Greiser, A., Fröhlich, M., Dietz, R., & Schulz‐Menger, J. (2007). Optimization and validation of a fully‐integrated pulse sequence for modified look‐locker inversion‐recovery (MOLLI) T1 mapping of the heart. Journal of Magnetic Resonance Imaging. https://doi.org/10.1002/jmri.21119
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