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Fully automated liquid extraction‐based surface sampling and ionization using a chip‐based robotic nanoelectrospray platform

Kertesz, Vilmos, Van Berkel, Gary J.·2010·Journal of Mass Spectrometry

Abstract

A fully automated liquid extraction‐based surface sampling device utilizing an Advion NanoMate chip‐based infusion nanoelectrospray ionization system is reported. Analyses were enabled for discrete spot sampling by using the Advanced User Interface of the current commercial control software. This software interface provided the parameter control necessary for the NanoMate robotic pipettor to both form and withdraw a liquid microjunction for sampling from a surface. The system was tested with three types of analytically important sample surface types, viz., spotted sample arrays on a MALDI plate, dried blood spots on paper, and whole‐body thin tissue sections from drug dosed mice. The qualitative and quantitative data were consistent with previous studies employing other liquid extraction‐based surface sampling techniques. Published in 2009 by John Wiley & Sons, Ltd.

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Metadata

Authors
Kertesz, V., & Van Berkel, G. J.
Venue
Journal of Mass Spectrometry
Publisher
Wiley
Published
2009-12-17
Volume
45
Issue
3
Pages
252-260
ISSN
  • 1076-5174 (ISSN-L)
  • 1096-9888
OpenAlex
W2035212554
Cited by
350
References
0
FWCI
7.44
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Fully automated liquid extraction‐based surface sampling and ionization using a chip‐based robotic nanoelectrospray platform. https://app.cochat.ai/papers/10.1002/jms.1709
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Kertesz, V., & Van Berkel, G. J. (2010). Fully automated liquid extraction‐based surface sampling and ionization using a chip‐based robotic nanoelectrospray platform. Journal of Mass Spectrometry. https://doi.org/10.1002/jms.1709

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