Understanding of COVID‐19 based on current evidence
Open accessAbstract
Since December 2019, a series of unexplained pneumonia cases have been reported in Wuhan, China. On 12 January 2020, the World Health Organization (WHO) temporarily named this new virus as the 2019 novel coronavirus (2019-nCoV). On 11 February 2020, the WHO officially named the disease caused by the 2019-nCoV as coronavirus disease (COVID-19). The COVID-19 epidemic is spreading all over the world, especially in China. Based on the published evidence, we systematically discuss the characteristics of COVID-19 in the hope of providing a reference for future studies and help for the prevention and control of the COVID-19 epidemic.
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The respiratory problems experienced by patients with COVID-19 significantly differ from other respiratory conditions (e.g., dry cough is common).
“This is because the respiratory problems experienced by patients with COVID-19 significantly differ from other respiratory conditions (e.g., dry cough is common [4, 19]) and COVID-19 patients' rapid deterioration to acute respiratory failure [2–4].”
From Effects of short-term breathing exercises on respiratory recovery in patients with COVID-19: a quasi-experimental study (2022) · cites this paper as [19]
Typically, a non-productive cough is associated with COVID-19; productive coughing may appear at a later stage [19].
“Typically, a non-productive cough is associated with COVID-19; productive coughing may appear at a later stage [19].”
From Effects of short-term breathing exercises on respiratory recovery in patients with COVID-19: a quasi-experimental study (2022) · cites this paper as [19]
Cites
Clinical characteristics of coronavirus disease 2019 in China
Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., Liu, L., Shan, H., Lei, C.-L., Hui, D. S. C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2002032 · Cited by 30,246 · see citing works
Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia
Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K. S. M., Lau, E. H. Y., Wong, J. Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001316 · Cited by 16,575 · see citing works
A new coronavirus associated with human respiratory disease in China
Wu, F., Zhao, S., Yu, B., Chen, Y.-M., Wang, W., Song, Z.-G., Hu, Y., Tao, Z.-W., Tian, J.-H., Pei, Y.-Y., et al. (2020) · Nature · doi:10.1038/s41586-020-2008-3 · Cited by 11,688 · see citing works
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C.-L., Abiona, O., Graham, B. S., & McLellan, J. S. (2020) · Science · doi:10.1126/science.abb2507 · Cited by 8,897 · see citing works
Hui, D. S., I Azhar, E., Madani, T. A., Ntoumi, F., Kock, R., Dar, O., Ippolito, G., Mchugh, T. D., Memish, Z. A., Drosten, C., et al. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.01.009 · Cited by 3,809 · see citing works
Single-cell RNA expression profiling of ACE2, the receptor of SARS-CoV-2
Zhao, Y., Zhao, Z., Wang, Y., Zhou, Y., Ma, Y., & Zuo, W. (2020) · doi:10.1101/2020.01.26.919985 · Cited by 860 · see citing works
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Zhang, W., Zhao, Y., Zhang, F., Wang, Q., Li, T., Liu, Z., Wang, J., Qin, Y., Zhang, X., Yan, X., et al. (2020) · Clinical Immunology · doi:10.1016/j.clim.2020.108393 · Cited by 1,266 · see citing works
Castagnoli, R., Votto, M., Licari, A., Brambilla, I., Bruno, R., Perlini, S., Rovida, F., Baldanti, F., & Marseglia, G. L. (2020) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2020.1467 · Cited by 1,085 · see citing works
SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development
Wang, M.-Y., Zhao, R., Gao, L.-J., Gao, X.-F., Wang, D.-P., & Cao, J.-M. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.587269 · Cited by 874 · see citing works
Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection
Liguori, C., Pierantozzi, M., Spanetta, M., Sarmati, L., Cesta, N., Iannetta, M., Ora, J., Mina, G. G., Puxeddu, E., Balbi, O., et al. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.05.037 · Cited by 212 · see citing works
Behavioral immune system linked to responses to the threat of COVID-19
Makhanova, A., & Shepherd, M. A. (2020) · Personality and Individual Differences · doi:10.1016/j.paid.2020.110221 · Cited by 188 · see citing works
Microstructure, pathophysiology, and potential therapeutics of COVID‐19: A comprehensive review
Singh, S. P., Pritam, M., Pandey, B., & Yadav, T. P. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26254 · Cited by 166 · see citing works
Kazu, İ. Y., & Kuvvetli, M. (2023) · Education and Information Technologies · doi:10.1007/s10639-023-11756-y · Cited by 83 · see citing works
Zhou, W., Shao, W., Zhang, Y., Liu, D., Liu, M., & Jin, T. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00292.2020 · Cited by 36 · see citing works
Ahmed-Hassan, H., Sisson, B., Shukla, R. K., Wijewantha, Y., Funderburg, N. T., Li, Z., Hayes, D., Demberg, T., & Liyanage, N. P. M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01979 · Cited by 47 · see citing works
Kader, M., Hossain, M. A., Reddy, V., Perera, N. K. P., & Rashid, M. (2022) · BMC Sports Science, Medicine and Rehabilitation · doi:10.1186/s13102-022-00451-z · Cited by 33 · see citing works
“, physician, Physiotherapist, occupational therapist, and nurses) can increase positive outcomes [6, 15, 19].”
Background
- Authors
- Sun, P., Lu, X., Xu, C., Sun, W., & Pan, B.
- Affiliations
- Central Hospital of Zibo (CN)
- Weifang Medical University (CN)
- Boxing People's Hospital (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Corresponding author
- Pan, Bo
- Venue
- Journal of Medical Virology
- Publisher
- Wiley
- Published
- 2020-03-05
- Volume
- 92
- Issue
- 6
- Pages
- 548-551
- ISSN
- 0146-6615 (ISSN-L)
- 1096-9071
- PMC
- PMC7228250
- OpenAlex
- W3008196127
- Cited by
- 1,107
- References
- 6
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 52 · 2023: 116 · 2022: 182 · 2021: 304 · 2020: 435 · 2019: 1
- FWCI
- 34.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Medical Virology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- COVID-19 pandemic, SARS-CoV-2, novel coronavirus, epidemic characteristics, epidemic prevention and control
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adenosine Monophosphate, Adrenal Cortex Hormones, Alanine, Animals, Antiviral Agents, China, Chiroptera, Communicable Disease Control, Humans, Pneumonia, Viral, Survival Analysis, Coronavirus Infections, Disease Management, Oseltamivir, Pandemics
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