The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Bone Tissue Engineering: State of the Art and Future Trends
Open accessAbstract
Summary: Although several major progresses have been introduced in the field of bone regenerative medicine during the years, current therapies, such as bone grafts, still have many limitations. Moreover, and in spite of the fact that material science technology has resulted in clear improvements in the field of bone substitution medicine, no adequate bone substitute has been developed and hence large bone defects/injuries still represent a major challenge for orthopaedic and reconstructive surgeons. It is in this context that TE has been emerging as a valid approach to the current therapies for bone regeneration/substitution. In contrast to classic biomaterial approach, TE is based on the understanding of tissue formation and regeneration, and aims to induce new functional tissues, rather than just to implant new spare parts. The present review pretends to give an exhaustive overview on all components needed for making bone tissue engineering a successful therapy. It begins by giving the reader a brief background on bone biology, followed by an exhaustive description of all the relevant components on bone TE, going from materials to scaffolds and from cells to tissue engineering strategies, that will lead to “engineered” bone. Scaffolds processed by using a methodology based on extrusion with blowing agents. magnified imageScaffolds processed by using a methodology based on extrusion with blowing agents.
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Cites
Multilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
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Tissue-engineered bone regeneration
Petite, H., Viateau, V., Bensaïd, W., Meunier, A., de Pollak, C., Bourguignon, M., Oudina, K., Sedel, L., & Guillemin, G. (2000) · Nature Biotechnology · doi:10.1038/79449 · Cited by 1,475
Repair of bone defects using synthetic mimetics of collagenous extracellular matrices
Lutolf, M. P., Weber, F. E., Schmoekel, H. G., Schense, J. C., Kohler, T., Müller, R., & Hubbell, J. A. (2003) · Nature Biotechnology · doi:10.1038/nbt818 · Cited by 850
Use of polyphosphazenes for skeletal tissue regeneration
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Self-citation
Cited by
Polymeric Scaffolds in Tissue Engineering Application: A Review
Dhandayuthapani, B., Yoshida, Y., Maekawa, T., & Kumar, D. S. (2011) · International Journal of Polymer Science · doi:10.1155/2011/290602 · Cited by 1,773
An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering
Gentile, P., Chiono, V., Carmagnola, I., & Hatton, P. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15033640 · Cited by 1,593
Biodegradable synthetic polymers: Preparation, functionalization and biomedical application
Tian, H., Tang, Z., Zhuang, X., Chen, X., & Jing, X. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.06.004 · Cited by 1,293
Collagen for bone tissue regeneration
Ferreira, A. M., Gentile, P., Chiono, V., & Ciardelli, G. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.06.014 · Cited by 938
Current development of biodegradable polymeric materials for biomedical applications
Song, R., Murphy, M., Li, C., Ting, K., Soo, C., & Zheng, Z. (2018) · Drug Design, Development and Therapy · doi:10.2147/dddt.s165440 · Cited by 915
Metadata
- Authors
- Salgado, A. J., Coutinho, O. P., & Reis, R. L.
- Venue
- Macromolecular Bioscience
- Publisher
- Wiley
- Published
- 2004-08-03
- Volume
- 4
- Issue
- 8
- Pages
- 743-765
- ISSN
- 1616-5187 (ISSN-L)
- 1616-5195
- OpenAlex
- W2139457077
- Cited by
- 1,681
- References
- 6
- FWCI
- 27.25
- Type
- journal article
- Language
- en
- Open access
- green
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