Synthesis, Characterization, and Properties Evaluation of Poly[( N ‐isopropylacrylamide)‐ co ‐ester]s
Abstract
Abstract Copolymerization behavior of cyclic ketene acetal like 5,6‐benzo‐2‐methylene‐1,3‐dioxepane (BMDO) with N ‐isopropylacrylamide (NIPAAm) is studied by free radical polymerization. Structural characterization is done using 1D and 2D NMR techniques. Under optimized reaction conditions, quantitative ring‐opening of BMDO took place during the copolymerizations leading to the formation of poly(NIPAAm‐ co ‐ester)s. The reactivity ratios for the copolymerization of BMDO and NIPAAm were determined using Kelen–Tüdõs method and found to be r BMDO = 0.11 and r NIPAAm = 7.31. Copolymers with low mol‐% of BMDO were found to be soluble in water and also showed hydrolytic degradability. Different degradable copolymers could be generated with varied glass transition temperatures and lower critical solution temperatures (LCSTs). magnified image
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Increasing interest in biodegradable polyesters and the versatility of RROP with respect to structures accessible via different monomers and their copolymerization with conventional vinyl monomers has changed the situation significantly.
“However, with the increasing interest in biodegradable polyesters and the versatility of RROP with respect to the structures accessible via very different monomers [25] and their copolymerization with conventional vinyl monomers [26 -34] has changed the situation significantly.”
From Ring-Opening Polymerization—An Introductory Review (2013) · cites this paper as [26]
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- Authors
- Ren, L., & Agarwal, S.
- Affiliations
- Philipps University of Marburg (DE)
- Corresponding author
- Agarwal, Seema
- ORCID
- Agarwal, Seema
- Venue
- Macromolecular Chemistry and Physics
- Publisher
- Wiley
- Published
- 2007-02-05
- Volume
- 208
- Issue
- 3
- Pages
- 245-253
- ISSN
- 1022-1352 (ISSN-L)
- 1521-3935
- OpenAlex
- W2141139727
- Cited by
- 60
- References
- 33
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 4
- FWCI
- 2.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Macromolecular Chemistry and Physics (publishedVersion)
- ERef Bayreuth (University of Bayreuth) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer Synthesis and Characterization
- Keywords
- N-isopropylacrylamide, cyclic ketene acetals, ring-opening copolymerization, radical polymerization, copolymer reactivity ratios, copolymer solubility, glass transition temperature, lower critical solution temperature, thermoresponsive polymers, biodegradable polymers
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