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Whole brain susceptibility mapping using compressed sensing

Open access
Wu, Bing, Li, Wei, Guidon, Arnaud, Liu, Chunlei·2012·Magnetic Resonance in Medicine

Abstract

The derivation of susceptibility from image phase is hampered by the ill‐conditioned filter inversion in certain k‐space regions. In this article, compressed sensing is used to compensate for the k‐space regions where direct filter inversion is unstable. A significantly lower level of streaking artifacts is produced in the resulting susceptibility maps for both simulated and in vivo data sets compared to outcomes obtained using the direct threshold method. It is also demonstrated that the compressed sensing based method outperforms regularization based methods. The key difference between the regularized inversions and compressed sensing compensated inversions is that, in the former case, the entire k‐space spectrum estimation is affected by the ill‐conditioned filter inversion in certain k‐space regions, whereas in the compressed sensing based method only the ill‐conditioned k‐space regions are estimated. In the susceptibility map calculated from the phase measurement obtained using a 3T scanner, not only are the iron‐rich regions well depicted, but good contrast between white and gray matter interfaces that feature a low level of susceptibility variations are also obtained. The correlation between the iron content and the susceptibility levels in iron‐rich deep nucleus regions is studied, and strong linear relationships are observed which agree with previous findings. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.

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Metadata

Authors
Wu, B., Li, W., Guidon, A., & Liu, C.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
2011-06-10
Volume
67
Issue
1
Pages
137-147
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W2152166807
Cited by
417
References
36
FWCI
11.72
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Whole brain susceptibility mapping using compressed sensing. https://app.cochat.ai/papers/10.1002/mrm.23000
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Wu, B., Li, W., Guidon, A., & Liu, C. (2012). Whole brain susceptibility mapping using compressed sensing. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.23000

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