The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Tissue specific perfusion imaging using arterial spin labeling
Abstract
Quantitative magnetic resonance measurements of regional tissue perfusion can be obtained using magnetically labeled arterial water as a diffusable tracer. Continuous labeling is achieved in flowing spins using adiabatic inversion. The effects of continuous labeling of proximal arterial spins and T1 relaxation in distal tissue magnetization result in a steady‐state change in tissue magnetization which is tissue specific, i.e., it can be quantified in units of blood flow per gram of tissue per unit time. This magnetization is sampled using standard imaging sequences. The theoretical basis for this method, including the effects of macromolecular spin saturation, is reviewed. Recent results demonstrating the successful implementation of this technique in vitro and in vivo in rat brain, heart, and kidney, and in human brain and kidney are presented, as well as the use of a separate RF coil for arterial labeling to produce selective perfusion images in rat brain. This approach allows quantitative perfusion images to be obtained completely non‐invasively at the resolution of 1 H MRI, and is useful in the clinical and investigational evaluation of organ physiology.
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Cites
Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.
Kwong, K. K., Belliveau, J. W., Chesler, D. A., Goldberg, I. E., Weisskoff, R. M., Poncelet, B. P., Kennedy, D. N., Hoppel, B. E., Cohen, M. S., & Turner, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5675 · Cited by 4,212
Functional mapping of the human visual cortex by magnetic resonance imaging
Belliveau, J. W., Kennedy, D. N., McKinstry, R. C., Buchbinder, B. R., Weisskoff, R. M., Cohen, M. S., Vevea, J. M., Brady, T. J., & Rosen, B. R. (1991) · Science · doi:10.1126/science.1948051 · Cited by 1,883
Cited by
Diffuse optics for tissue monitoring and tomography
Durduran, T., Choe, R., Baker, W. B., & Yodh, A. G. (2010) · Reports on Progress in Physics · doi:10.1088/0034-4885/73/7/076701 · Cited by 1,161
Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker
Wang, Y., & Liu, T. (2015) · Magnetic Resonance in Medicine · doi:10.1002/mrm.25358 · Cited by 878
Real-time fMRI neurofeedback: Progress and challenges
Sulzer, J., Haller, S., Scharnowski, F., Weiskopf, N., Birbaumer, N., Blefari, M. L., Bruehl, A. B., Cohen, L. G., deCharms, R. C., Gassert, R., et al. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.03.033 · Cited by 453
Detre, J. A., & Alsop, D. C. (1999) · European Journal of Radiology · doi:10.1016/s0720-048x(99)00050-9 · Cited by 299
Self-citationYe, F. Q., Mattay, V. S., Jezzard, P., Frank, J. A., Weinberger, D. R., & McLaughlin, A. C. (1997) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910370215 · Cited by 294
Metadata
- Authors
- Detre, J. A., Zhang, W., Roberts, D. A., Silva, A. C., Williams, D. S., Grandis, D. J., Koretsky, A. P., & Leigh, J. S.
- Venue
- NMR in Biomedicine
- Publisher
- Wiley
- Published
- 1994-03
- Volume
- 7
- Issue
- 1-2
- Pages
- 75-82
- ISSN
- 0952-3480 (ISSN-L)
- 1099-1492
- OpenAlex
- W2156057467
- Cited by
- 335
- References
- 2
- FWCI
- 6.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Detre, J. A., Zhang, W., Roberts, D. A., Silva, A. C., Williams, D. S., Grandis, D. J., Koretsky, A. P., & Leigh, J. S. (1994). Tissue specific perfusion imaging using arterial spin labeling. NMR in Biomedicine. https://doi.org/10.1002/nbm.1940070112
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