The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Effects of Supplementation with Curcuminoids on Dyslipidemia in Obese Patients: A Randomized Crossover Trial
Open accessAbstract
Dyslipidemia is a leading risk factor for cardiovascular disease and is also a common feature of obesity. Curcumin is a bioactive phytochemical with well‐known antioxidant, anti‐inflammatory, and cardioprotective properties. The present study investigated the hypolipidemic activity of curcumin in obese individuals. Participants (n = 30) were treated with curcuminoids (1 g/day), or placebo in a randomized, double‐blind, placebo‐controlled, crossover trial. Serum concentrations of total cholesterol, triglycerides, low‐density lipoprotein cholesterol and high‐density lipoprotein cholesterol, together with anthropometric parameters and high‐sensitivity C‐reactive protein were measured before and after each treatment period. Anthropometric parameters including weight, BMI, waist circumference, hip circumference, arm circumference, and body fat remained statistically unchanged by the end of trial (p > 0.05). As for the lipid profile parameters, serum triglycerides were significantly reduced following curcumin supplementation (p = 0.009). However, curcuminoids were not found to affect serum levels of total cholesterol, low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol, and high‐sensitivity C‐reactive protein (p > 0.05). In summary, the findings of the present study indicated that curcuminoid supplementation (1 g/day for 30 days) leads to a significant reduction in serum triglycerides concentrations but do not have a significant influence on other lipid profile parameters as well as body mass index and body fat. Copyright © 2012 John Wiley & Sons, Ltd.
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Mechanisms linking obesity to insulin resistance and type 2 diabetes
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature · doi:10.1038/nature05482 · Cited by 5,448
A central role for JNK in obesity and insulin resistance
Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature · doi:10.1038/nature01137 · Cited by 3,359
Cited by
Curcumin: A Review of Its Effects on Human Health
Hewlings, S., & Kalman, D. (2017) · Foods · doi:10.3390/foods6100092 · Cited by 2,720
Effects of curcumin on HDL functionality
Ganjali, S., Blesso, C. N., Banach, M., Pirro, M., Majeed, M., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.02.008 · Cited by 186
Sahebkar, A., Mohammadi, A., Atabati, A., Rahiman, S., Tavallaie, S., Iranshahi, M., Akhlaghi, S., Ferns, G. A., & Ghayour‐Mobarhan, M. (2013) · Phytotherapy Research · doi:10.1002/ptr.4952 · Cited by 183
Self-citationCurcuminoids for the management of hypertriglyceridaemia
Sahebkar, A. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2013.140-c1 · Cited by 172
Self-citationRegulation of PCSK9 by nutraceuticals
Momtazi, A. A., Banach, M., Pirro, M., Katsiki, N., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.023 · Cited by 131
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Metadata
- Authors
- Mohammadi, A., Sahebkar, A., Iranshahi, M., Amini, M., Khojasteh, R., Ghayour‐Mobarhan, M., & Ferns, G. A.
- Venue
- Phytotherapy Research
- Publisher
- Wiley
- Published
- 2012-05-21
- Volume
- 27
- Issue
- 3
- Pages
- 374-379
- ISSN
- 0951-418X (ISSN-L)
- 1099-1573
- OpenAlex
- W1930004935
- Cited by
- 277
- References
- 2
- FWCI
- 5.15
- Type
- journal article
- Language
- en
- Open access
- green
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