Curcuminoids Modulate Pro‐Oxidant–Antioxidant Balance but not the Immune Response to Heat Shock Protein 27 and Oxidized LDL in Obese Individuals
Abstract
Curcuminoids have potentially important functional qualities including anti‐inflammatory and antioxidant properties. In this randomized double‐blind placebo‐controlled cross‐over trial, the effects of a curcuminoid supplement on serum pro‐oxidant–antioxidant balance (PAB) and antibody titres to Hsp27 (anti‐Hsp27) and oxLDL (anti‐oxLDL) were investigated. Thirty obese individuals were randomized to receive either curcuminoids (1 g/day) or placebo for a period of 30 days. After a wash‐out period of 2 weeks, subjects were crossed over to the alternate regimen for another 30 days. Serum PAB along with anti‐Hsp27 and anti‐oxLDL titres was measured at the beginning and at the end of each study period. There was no significant carry‐over effect for any of the assessed parameters. Curcuminoid supplementation was associated with a significant decrease in PAB (p = 0.044). However, no significant change was observed in serum concentrations of anti‐Hsp27 or anti‐oxLDL (p > 0.05). These findings suggest that oral curcuminoids supplementation (1g/day) is effective in reducing oxidative stress burden, though this needs to be validated in larger study populations. Copyright © 2013 John Wiley & Sons, Ltd.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Curcuminoids supplementation resulted in no significant change in serum concentrations of oxidative markers anti-Hsp27 and anti-oxidized LDL in obese individuals.
“And curcuminoids supplementation, which have potentially important functional qualities including anti-inflammatory and antioxidant properties, resulted in no significant change in serum concentrations of oxidative markers anti-Hsp27 and anti-oxidized LDL in obese individuals [39].”
From The influence of obesity on the effects of spirulina supplementation in the human metabolic response of Korean elderly (2016) · cites this paper as [39]
Cites
Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508 · see citing works
Kuczmarski, R. J. (1994) · JAMA · doi:10.1001/jama.272.3.205 · Cited by 2,362 · see citing works
Curcumin as “Curecumin”: From kitchen to clinic
Goel, A., Kunnumakkara, A. B., & Aggarwal, B. B. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.016 · Cited by 2,220 · see citing works
The Role Of Glutamate Neurotoxicity In Hypoxic-Ischemic Neuronal Death
Choi, D. W., & Rothman, S. M. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.13.030190.001131 · Cited by 2,210 · see citing works
Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus
Wilson, P. W. F., D’Agostino, R. B., Parise, H., SULLIVAN, L. M., & Meigs, J. B. (2005) · Circulation · doi:10.1161/circulationaha.105.539528 · Cited by 2,061 · see citing works
Antioxidant and radical scavenging properties of curcumin
Ak, T. P., & Gülçın, İ. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.05.003 · Cited by 1,942 · see citing works
Increasing Prevalence of Overweight Among US Adults
Kuczmarski, R. J. (1994) · JAMA · doi:10.1001/jama.1994.03520030047027 · Cited by 1,574 · see citing works
Dose escalation of a curcuminoid formulation
Lao, C. D., Ruffin, M. T., Normolle, D. P., Heath, D. D., Murray, S. I., Bailey, J. M., Boggs, M. E., Crowell, J. A., Rock, C. L., & Brenner, D. E. (2006) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-6-10 · Cited by 1,400 · see citing works
Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
Anand, P., Thomas, S. G., Kunnumakkara, A. B., Sundaram, C., Harikumar, K. B., Sung, B., Tharakan, S. T., Misra, K., Priyadarsini, K. I., Rajasekharan, K. N., et al. (2008) · Biochemical Pharmacology · doi:10.1016/j.bcp.2008.08.008 · Cited by 1,205 · see citing works
Quinn, M. T., Parthasarathy, S., Fong, L. G., & Steinberg, D. I. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.9.2995 · Cited by 1,138 · see citing works
Free radical scavenging activities of mushroom polysaccharide extracts
Liu, F., Ooi, V. E. C., & Chang, S. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)00004-0 · Cited by 945 · see citing works
Lewis A. Conner Memorial Lecture
Steinberg, D. H. (1997) · Circulation · doi:10.1161/01.cir.95.4.1062 · Cited by 743 · see citing works
Bharti, A. C., Donato, N. J., Singh, S., & Aggarwal, B. B. (2003) · Blood · doi:10.1182/blood-2002-05-1320 · Cited by 688 · see citing works
Lipoprotein oxidation and lipoprotein-induced cytotoxicity.
Hessler, J. R., Morel, D. W., Lewis, L. J., & Chisolm, G. M. (1983) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.3.3.215 · Cited by 541 · see citing works
Chandran, B., & Goel, A. (2012) · Phytotherapy Research · doi:10.1002/ptr.4639 · Cited by 527 · see citing works
Adolescent Overweight and Future Adult Coronary Heart Disease
Bibbins-Domingo, K. B., Coxson, P. G., Pletcher, M. J., Lightwood, J. M., & Goldman, L. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa073166 · Cited by 524 · see citing works
Baum, L., & Ng, A. (2004) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6403 · Cited by 483 · see citing works
Oxidized LDL and HDL: antagonists in atherothrombosis
Mertens, A. C., & Holvoet, P. (2001) · The FASEB Journal · doi:10.1096/fj.01-0273rev · Cited by 410 · see citing works
Oxidative Modification of LDL and Atherogenesis
Steinberg, D. H. (1998) · Medical science symposia series · doi:10.1007/978-94-011-5022-4_16 · Cited by 330 · see citing works
Daniel, S., Limson, J. L., Dairam, A., Watkins, G. M., & Daya, S. (2003) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2003.10.014 · Cited by 324 · see citing works
The aging paradox: free radical theory of aging
Ashok, B. T., & Ali, R. (1999) · Experimental Gerontology · doi:10.1016/s0531-5565(99)00005-4 · Cited by 318 · see citing works
Ahsan, H., Parveen, N., Khan, N. U.-D., & Hadi, S. M. (1999) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(99)00096-4 · Cited by 282 · see citing works
Mohammadi, A., Sahebkar, A., Iranshahi, M., Amini, M., Khojasteh, R., Ghayour‐Mobarhan, M., & Ferns, G. A. (2012) · Phytotherapy Research · doi:10.1002/ptr.4715 · Cited by 277 · see citing works
Self-citationAlamdari, D. H., Paletas, K., Pegiou, T., Sarigianni, M., Befani, C. D., & Koliakos, G. (2006) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.10.017 · Cited by 238 · see citing works
Concentration dependent antioxidant/pro-oxidant activity of curcumin
Banerjee, A., Kunwar, A., Mishra, B., & Priyadarsini, K. I. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.05.009 · Cited by 203 · see citing works
Rajagopalan, R., Kode, A., Varma, P. S., Rajasekaran, K. N., & Menon, V. P. (2004) · PubMed · Cited by 183 · see citing works
Parizadeh, S. M. R., Azarpazhooh, M. R., Moohebati, M., Nematy, M., Ghayour‐Mobarhan, M., Tavallaie, S., Rahsepar, A. A., Amini, M., Sahebkar, A., Mohammadi, M., et al. (2011) · Lipids · doi:10.1007/s11745-010-3517-x · Cited by 182 · see citing works
Self-citationPanahi, Y., Sahebkar, A., Parvin, S., & Saadat, A. (2012) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012040 · Cited by 176 · see citing works
Self-citationPanahi, Y., Sahebkar, A., Amiri, M., Davoudi, S. M., Beiraghdar, F., Hoseininejad, S. L., & Kolivand, M. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511006544 · Cited by 175 · see citing works
Self-citationSahebkar, A. (2012) · BioFactors · doi:10.1002/biof.1062 · Cited by 171 · see citing works
Self-citationCurcumin modulates free radical quenching in myocardial ischaemia in rats
Panchatcharam, M., Miriyala, S., Srinivasan, A., Manohar, B. M., Lokanadam, B., & Puvanakrishnan, R. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.01.030 · Cited by 150 · see citing works
Are Anti–Oxidized Low-Density Lipoprotein Antibodies Pathogenic or Protective?
Shoenfeld, Y., Wu, R., Dearing, L. D., & Matsuura, E. (2004) · Circulation · doi:10.1161/01.cir.0000143225.07377.ea · Cited by 147 · see citing works
Development and tissue‐specific distribution of mouse small heat shock protein hsp25
Gernold, M., Knauf, U., Gaestel, M., Stahl, J., & Kloetzel, P. (1993) · Developmental Genetics · doi:10.1002/dvg.1020140204 · Cited by 134 · see citing works
Alamdari, D. H., Ghayour‐Mobarhan, M., Tavallaie, S., Parizadeh, M. R., Moohebati, M., Ghafoori, F., Kazemi‐Bajestani, S. M. R., Paletas, K., Pegiou, T., & Koliakos, G. (2007) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2007.12.008 · Cited by 126 · see citing works
Self-citationCurcumin suppresses growth and induces apoptosis in primary effusion lymphoma
Shahab Uddin, M. S., Hussain, A. R., Manogaran, P. S., Al‐Hussein, K., Platanias, L. C., Gutiérrez, M. I., & Bhatia, K. G. (2005) · Oncogene · doi:10.1038/sj.onc.1208864 · Cited by 123 · see citing works
Antioxidant activities of curcumin and combinations of this curcuminoid with other phytochemicals
Aftab, N. F., & Vieira, A. V. (2009) · Phytotherapy Research · doi:10.1002/ptr.2960 · Cited by 116 · see citing works
Pauli, D., Tonka, C.-H., Tissieres, A., & Arrigo, A. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.111.3.817 · Cited by 106 · see citing works
Curcumin Inhibits Melanogenesis in Human Melanocytes
Tu, C., Lin, M., Lu, S., Qi, X., Zhang, R., & Zhang, Y. (2011) · Phytotherapy Research · doi:10.1002/ptr.3517 · Cited by 87 · see citing works
Manjunatha, H., & Srinivasan, K. (2007) · Lipids · doi:10.1007/s11745-007-3120-y · Cited by 82 · see citing works
Antibody titres to heat shock protein 27 are elevated in patients with acute coronary syndrome
Ghayour‐Mobarhan, M., Sahebkar, A., Parizadeh, S. M. R., Moohebati, M., Tavallaie, S., Kazemi‐Bajestani, S. M. R., Esmaeili, H., & Ferns, G. A. (2008) · International Journal of Experimental Pathology · doi:10.1111/j.1365-2613.2008.00586.x · Cited by 71 · see citing works
Self-citationEsmaillzadeh, A., Mirmiran, P., & Azizi, F. (2006) · Public Health Nutrition · doi:10.1079/phn2005833 · Cited by 70 · see citing works
Curcumin‐Induced Cell Death in Two Leukemia Cell Lines: K562 and Jurkat
Duvoix, A., Morceau, F., Schnekenburger, M., Delhalle, S., Galteau, M. M., Dicato, M. A., & Diederich, M. F. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1299.071 · Cited by 47 · see citing works
Heat Shock Proteins and Autoimmunity in Patients with Carotid Atherosclerosis
Riganò, R., Profumo, E., Buttari, B., Tagliani, A., Petrone, L., d’Amati, G., Ippoliti, F., Capoano, R., Fumagalli, L., Salvati, B., et al. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1381.001 · Cited by 44 · see citing works
Serum zinc and copper status in Iranian patients with pemphigus vulgaris
Yazdanpanah, M. J., Ghayour‐Mobarhan, M., Taji, A. R., Javidi, Z., Pezeshkpoor, F., Tavallaie, S., Akram, M., Esmaily, H., Shojaie‐Noori, S., Khoddami, M., et al. (2011) · International Journal of Dermatology · doi:10.1111/j.1365-4632.2011.04968.x · Cited by 41 · see citing works
Self-citationGhayour‐Mobarhan, M., Alamdari, D. H., Moohebati, M., Sahebkar, A., Nematy, M., Safarian, M., Azimi–Nezhad, M., Parizadeh, S. M. R., Tavallaie, S., Koliakos, G., et al. (2009) · Angiology · doi:10.1177/0003319709333868 · Cited by 37 · see citing works
Self-citationModulatory effects of curcumin and resveratrol on lung carcinogenesis in mice
Malhotra, A., Nair, P., & Dhawan, D. K. (2009) · Phytotherapy Research · doi:10.1002/ptr.3087 · Cited by 31 · see citing works
Pourghadamyari, H., Moohebati, M., Parizadeh, S. M. R., Falsoleiman, H., Dehghani, M., Fazlinezhad, A., Akhlaghi, S., Tavallaie, S., Sahebkar, A., Paydar, R., et al. (2010) · Cell Stress and Chaperones · doi:10.1007/s12192-010-0241-7 · Cited by 31 · see citing works
Self-citationMa, J., Phillips, L. M., Wang, Y., Dai, T., LaPage, J. A., Natarajan, R. D., & Adler, S. G. (2010) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-10-67 · Cited by 28 · see citing works
Ghayour‐Mobarhan, M., Lamb, D., Vaidya, N., Livingstone, C., Wang, T., & Ferns, G. A. (2005) · Angiology · doi:10.1177/000331970505600108 · Cited by 28 · see citing works
Self-citationNematy, M., Sakhdari, A., Moghaddam, P. A., Aliabadi, M., Kimiagar, M., Ilaty, A. A., Azimi–Nezhad, M., Shakeri, M. T., Ghayour‐Mobarhan, M., Sahebkar, A., et al. (2009) · The Scientific World JOURNAL · doi:10.1100/tsw.2009.139 · Cited by 28 · see citing works
Self-citationTucker, N. R., Ustyugov, A. A., Bryantsev, A. L., Konkel, M. E., & Shelden, E. A. (2009) · Cell Stress and Chaperones · doi:10.1007/s12192-009-0105-1 · Cited by 26 · see citing works
Sahebkar, A., Pourghadamyari, H., Moohebati, M., Parizadeh, S. M. R., Falsoleiman, H., Dehghani, M., Fazlinezhad, A., Akhlaghi, S., Tavallaie, S., Paydar, R., et al. (2011) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2011.09.011 · Cited by 24 · see citing works
Self-citationTara, F., Rayman, M. P., Boskabadi, H., Ghayour‐Mobarhan, M., Sahebkar, A., Alamdari, D. H., Razavi, B. S., Tavallaie, S., Azimi–Nezhad, M., Shakeri, M. T., et al. (2010) · Journal of Perinatal Medicine · doi:10.1515/jpm.2010.068 · Cited by 22 · see citing works
Self-citationProoxidant-antioxidant balance in stroke patients and 6-month prognosis.
Parizadeh, M. R., Azarpazhooh, M. R., Mobarra, N., Nematy, M., Alamdari, D. H., Tavalaie, S., Sahebkar, A., Hassankhani, B., Ferns, G. A., & Ghayour‐Mobarhan, M. (2011) · PubMed · Cited by 20 · see citing works
Self-citationChanges in Plasma Level of Heat Shock Protein 27 After Acute Coronary Syndrome
Heidari‐Bakavoli, A., Sahebkar, A., Mobara, N., Moohebati, M., Tavallaie, S., Rahsepar, A. A., Kazemi, A., Alavi, M.-S., Ghayour‐Mobarhan, M., & Ferns, G. A. (2011) · Angiology · doi:10.1177/0003319711406104 · Cited by 17 · see citing works
Self-citationEsmaillzadeh, A., Mirmiran, P., & Azizi, F. (2005) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.75.5.347 · Cited by 14 · see citing works
Boskabadi, H., Omran, F., Tara, F., Rayman, M., Ghayour‐Mobarhan, M., Sahebkar, A., Tavallaie, S., Shakeri, M. T., Alamdari, D., Kiani, M. A., et al. (2010) · Surrey Research Insight Open Access (The University of Surrey) · Cited by 10 · see citing works
Self-citationAmin, F., & Bano, B. (2012) · Current Proteomics · doi:10.2174/157016412799746227 · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Curcumin: A Review of Its Effects on Human Health
Hewlings, S., & Kalman, D. (2017) · Foods · doi:10.3390/foods6100092 · Cited by 2,720 · see citing works
Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
Kunnumakkara, A. B., Bordoloi, D., Padmavathi, G., Monisha, J., Roy, N. K., Prasad, S., & Aggarwal, B. B. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13621 · Cited by 1,068 · see citing works
Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies
Mirzaei, H., Shakeri, A., Rashidi, B., Jalili, A., Banikazemi, Z., & Sahebkar, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.11.098 · Cited by 519 · see citing works
Self-citationCellular and molecular mechanisms of curcumin in prevention and treatment of disease
Patel, S. S., Acharya, A., Ray, R. S., Agrawal, R. K., Raghuwanshi, R., & Jain, P. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1552244 · Cited by 518 · see citing works
The therapeutic potential of curcumin: A review of clinical trials
Salehi, B., Stojanović-Radić, Z. Z., Matejić, J. S., Sharifi‐Rad, M., Kumar, N. V. A., Martins, N. A., & Sharifi‐Rad, J. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.12.016 · Cited by 497 · see citing works
Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial
Rahmani, S., Asgary, S., Askari, G., Keshvari, M., Hatamipour, M., Feizi, A., & Sahebkar, A. (2016) · Phytotherapy Research · doi:10.1002/ptr.5659 · Cited by 462 · see citing works
Self-citationPanahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Majeed, M. A., & Sahebkar, A. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2014.12.019 · Cited by 407 · see citing works
Self-citationImmune modulation by curcumin: The role of interleukin-10
Mollazadeh, H., Cicero, A. F. G., Blesso, C. N., Pirro, M., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1358139 · Cited by 382 · see citing works
Self-citationPanahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Simental‐Mendía, L. E., Majeed, M. A., & Sahebkar, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.05.037 · Cited by 329 · see citing works
Self-citationCurcuminoid Treatment for Knee Osteoarthritis: A Randomized Double‐Blind Placebo‐Controlled Trial
Panahi, Y., Rahimnia, A., Sharafi, M., Alishiri, G., Saburi, A., & Sahebkar, A. (2014) · Phytotherapy Research · doi:10.1002/ptr.5174 · Cited by 310 · see citing works
Self-citationCurcumin Formulations for Better Bioavailability: What We Learned from Clinical Trials Thus Far?
Hegde, M., Girisa, S., BharathwajChetty, B., Vishwa, R., & Kunnumakkara, A. B. (2023) · ACS Omega · doi:10.1021/acsomega.2c07326 · Cited by 306 · see citing works
Sahebkar, A. (2013) · Phytotherapy Research · doi:10.1002/ptr.5045 · Cited by 304 · see citing works
Self-citationPanahi, Y., Kianpour, P., Mohtashami, R., Jafari, R., Simental‐Mendía, L. E., & Sahebkar, A. (2017) · Drug Research · doi:10.1055/s-0043-100019 · Cited by 288 · see citing works
Self-citationPanahi, Y., Kianpour, P., Mohtashami, R., Jafari, R., Simental‐Mendía, L. E., & Sahebkar, A. (2016) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000406 · Cited by 269 · see citing works
Self-citationAnti-Obesity Effects of Polyphenol Intake: Current Status and Future Possibilities
Boccellino, M., & D’Angelo, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165642 · Cited by 265 · see citing works
Curcumin: A new candidate for melanoma therapy?
Mirzaei, H., Naseri, G., Rezaee, R., Mohammadi, M., Banikazemi, Z., Mirzaei, H. R., Salehi, H., Peyvandi, M., Pawelek, J. M., & Sahebkar, A. (2016) · International Journal of Cancer · doi:10.1002/ijc.30224 · Cited by 254 · see citing works
Self-citationQin, S., Huang, L., Gong, J., Shen, S., Huang, J., Ren, H., & Hu, H. (2017) · Nutrition Journal · doi:10.1186/s12937-017-0293-y · Cited by 251 · see citing works
Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Karimian, M. S., Majeed, M. A., & Sahebkar, A. (2016) · Inflammopharmacology · doi:10.1007/s10787-016-0301-4 · Cited by 238 · see citing works
Self-citationSahebkar, A., Șerban, M.-C., Ursoniu, S., & Banach, M. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.01.005 · Cited by 238 · see citing works
Self-citationPanahi, Y., Khalili, N., Hosseini, M. S., Abbasinazari, M., & Sahebkar, A. (2014) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2014.07.006 · Cited by 231 · see citing works
Self-citationCurcumin as a MicroRNA Regulator in Cancer: A Review
Momtazi‐Borojeni, A. A., Shahabipour, F., Khatibi, S., Johnston, T. P., Pirro, M., & Sahebkar, A. (2016) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/112_2016_3 · Cited by 230 · see citing works
Self-citationPanahi, Y., Alishiri, G. H., Parvin, S., & Sahebkar, A. (2015) · Journal of Dietary Supplements · doi:10.3109/19390211.2015.1008611 · Cited by 229 · see citing works
Self-citationMohammadi, A., Blesso, C. N., Barreto, G. E., Banach, M., Majeed, M. A., & Sahebkar, A. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.12.005 · Cited by 226 · see citing works
Self-citationCurcuminoids modify lipid profile in type 2 diabetes mellitus: A randomized controlled trial
Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Reiner, Ž., Majeed, M. A., & Sahebkar, A. (2017) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2017.05.006 · Cited by 222 · see citing works
Self-citationCurcumin, hemostasis, thrombosis, and coagulation
Keihanian, F., Saeidinia, A., Bagheri, R. K., Johnston, T. P., & Sahebkar, A. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.26249 · Cited by 220 · see citing works
Self-citationThe Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity
Zhao, Y., Chen, B., Shen, J., Wan, L., Zhu, Y., Yi, T., & Xiao, Z. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/1459497 · Cited by 214 · see citing works
Curcumin: A natural modulator of immune cells in systemic lupus erythematosus
Momtazi‐Borojeni, A. A., Haftcheshmeh, S. M., Esmaeili, S., Johnston, T. P., Abdollahi, E., & Sahebkar, A. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.11.016 · Cited by 212 · see citing works
Self-citationGanjali, S., Sahebkar, A., Mahdipour, E., Jamialahmadi, K., Torabi, S., Akhlaghi, S., Ferns, G. A., Parizadeh, S. M. R., & Ghayour‐Mobarhan, M. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/898361 · Cited by 211 · see citing works
Self-citationIs curcumin bioavailability a problem in humans: lessons from clinical trials
Kunnumakkara, A. B., Harsha, C., Banik, K., Vikkurthi, R., Sailo, B. L., Bordoloi, D., Gupta, S. C., & Aggarwal, B. B. (2019) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2019.1650914 · Cited by 211 · see citing works
Panahi, Y., Saadat, A., Beiraghdar, F., & Sahebkar, A. (2014) · Phytotherapy Research · doi:10.1002/ptr.5149 · Cited by 204 · see citing works
Self-citationKunnumakkara, A. B., Hegde, M., Parama, D., Girisa, S., Kumar, A., Daimary, U. D., Garodia, P., Yenisetti, S. C., Oommen, O. V., & Aggarwal, B. B. (2023) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.2c00012 · Cited by 222 · see citing works
Yang, Y., Su, Y., Yang, H., Lee, Y., Chou, J. I., & Ueng, K. (2014) · Phytotherapy Research · doi:10.1002/ptr.5197 · Cited by 200 · see citing works
Curcumin as a natural regulator of monocyte chemoattractant protein-1
Karimian, M. S., Pirro, M., Majeed, M. A., & Sahebkar, A. (2016) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2016.10.001 · Cited by 196 · see citing works
Self-citationEsmaily, H., Sahebkar, A., Iranshahi, M., Ganjali, S., Mohammadi, A., Ferns, G. A., & Ghayour‐Mobarhan, M. (2015) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-015-2160-z · Cited by 194 · see citing works
Self-citationCurcumin nanofibers for the purpose of wound healing
Fereydouni, N., Darroudi, M., Movaffagh, J., Shahroodi, A., Butler, A. E., Ganjali, S., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27362 · Cited by 197 · see citing works
Self-citationTeymouri, M., Pirro, M., Johnston, T. P., & Sahebkar, A. (2016) · BioFactors · doi:10.1002/biof.1344 · Cited by 193 · see citing works
Self-citationPanahi, Y., Ghanei, M., Hajhashemi, A., & Sahebkar, A. (2014) · Journal of Dietary Supplements · doi:10.3109/19390211.2014.952865 · Cited by 192 · see citing works
Self-citationLipid-modifying effects of nutraceuticals: An evidence-based approach
Sahebkar, A., Șerban, M.-C., Gluba-Brzózka, A., Mikhailidis, D. P., Cicero, A. F. G., Rysz, J., & Banach, M. (2016) · Nutrition · doi:10.1016/j.nut.2016.04.007 · Cited by 188 · see citing works
Self-citationPanahi, Y., Badeli, R., Karami, G., & Sahebkar, A. (2014) · Phytotherapy Research · doi:10.1002/ptr.5211 · Cited by 187 · see citing works
Self-citationEffects of curcumin on HDL functionality
Ganjali, S., Blesso, C. N., Banach, M., Pirro, M., Majeed, M., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.02.008 · Cited by 186 · see citing works
Self-citationDerosa, G., Maffioli, P., Simental‐Mendía, L. E., Bo, S., & Sahebkar, A. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.07.004 · Cited by 180 · see citing works
Self-citationRole of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases
Momtazi‐Borojeni, A. A., Derosa, G., Maffioli, P., Banach, M., & Sahebkar, A. (2016) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-016-0202-7 · Cited by 179 · see citing works
Self-citationCurcumin: A potentially powerful tool to reverse cisplatin-induced toxicity
Rezaee, R., Momtazi‐Borojeni, A. A., Monemi, A., & Sahebkar, A. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.12.037 · Cited by 176 · see citing works
Self-citationSahebkar, A., & Henrotin, Y. E. (2015) · Pain Medicine · doi:10.1093/pm/pnv024 · Cited by 174 · see citing works
Self-citationRecent advances in pharmacotherapy for hypertriglyceridemia
Sahebkar, A., Chew, G. T., & Watts, G. F. (2014) · Progress in Lipid Research · doi:10.1016/j.plipres.2014.07.002 · Cited by 166 · see citing works
Self-citationTherapeutic use of curcumin‐encapsulated and curcumin‐primed exosomes
Nosrati‐Oskouie, M., Aghili‐Moghaddam, N. S., Butler, A. E., Zamani, P., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27615 · Cited by 162 · see citing works
Self-citationPiperine and Its Role in Chronic Diseases
Derosa, G., Maffioli, P., & Sahebkar, A. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-41334-1_8 · Cited by 151 · see citing works
Self-citationSahebkar, A. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.09.012 · Cited by 149 · see citing works
Self-citationEl-Bahr, S. M. (2014) · Phytotherapy Research · doi:10.1002/ptr.5239 · Cited by 134 · see citing works
Regulation of PCSK9 by nutraceuticals
Momtazi, A. A., Banach, M., Pirro, M., Katsiki, N., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.023 · Cited by 131 · see citing works
Self-citationPolyphenols and atherosclerosis: A critical review of clinical effects on LDL oxidation
Ahmadi, A., Jamialahmadi, T., & Sahebkar, A. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106414 · Cited by 111 · see citing works
Self-citationCurcumin Supplementation and Human Disease: A Scoping Review of Clinical Trials
Panknin, T., Howe, C. L., Hauer, M., Bucchireddigari, B., Rossi, A., & Funk, J. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054476 · Cited by 111 · see citing works
Panahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Soflaei, S. S., Majeed, M. A., & Sahebkar, A. (2016) · Nutrition · doi:10.1016/j.nut.2016.03.018 · Cited by 106 · see citing works
Self-citationAkbari, M., Lankarani, K. B., Tabrizi, R., Ghayour‐Mobarhan, M., Peymani, P., Ferns, G. A., Ghaderi, A., & Asemi, Z. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00649 · Cited by 105 · see citing works
Self-citationPharmacological Mechanisms and Clinical Applications of Curcumin: Update
Hao, M., Chu, Y., Lei, J., Yao, Z., Wang, P., Chen, Z., Wang, K., Sang, X., Han, X., Wang, L., et al. (2022) · Aging and Disease · doi:10.14336/ad.2022.1101 · Cited by 100 · see citing works
Therapeutic Applications of Curcumin Nanomedicine Formulations in Cardiovascular Diseases
Salehi, B., Prado-Audelo, M. L. D., Cortés, H., Leyva‐Gómez, G., Stojanović-Radić, Z. Z., Singh, Y. D., Patra, J. K., Das, G., Martins, N. A., Martorell, M., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030746 · Cited by 99 · see citing works
Mokgalaboni, K., Ntamo, Y., Ziqubu, K., Nyambuya, T. M., Nkambule, B. B., Mazibuko-Mbeje, S. E., Gabuza, K., Chellan, N., Tiano, L., & Dludla, P. V. (2021) · Food & Function · doi:10.1039/d1fo02696h · Cited by 99 · see citing works
Al-Karawi, D., Mamoori, D. A. A., & Tayyar, Y. (2015) · Phytotherapy Research · doi:10.1002/ptr.5524 · Cited by 92 · see citing works
Curcumin and Weight Loss: Does It Work?
Kasprzak‐Drozd, K., Oniszczuk, T., Gancarz, M., Kondracka, A., Rusinek, R., & Oniszczuk, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020639 · Cited by 87 · see citing works
Razavi-Azarkhiavi, K., Iranshahy, M., Sahebkar, A., Shirani, K., & Karimi, G. (2016) · Nutrition and Cancer · doi:10.1080/01635581.2016.1187280 · Cited by 86 · see citing works
Self-citationFranco‐Robles, E., Campos-Cervantes, A., Murillo-Ortiz, B. O., Segovia, J., López-Briones, S., Vergara, P., Pérez‐Vázquez, V., Ortíz, M. S. S., & Ramı́rez-Emiliano, J. (2013) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0133 · Cited by 81 · see citing works
Promising anti‐tumor properties of bisdemethoxycurcumin: A naturally occurring curcumin analogue
Ramezani, M., Hatamipour, M., & Sahebkar, A. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25795 · Cited by 80 · see citing works
Self-citationCytoprotective Effects of Natural Compounds against Oxidative Stress
Mehta, J., Rayalam, S., & Wang, X. (2018) · Antioxidants · doi:10.3390/antiox7100147 · Cited by 80 · see citing works
Saraf‐Bank, S., Ahmadi, A., Paknahad, Z., Maracy, M. R., & Nourian, M. (2019) · Phytotherapy Research · doi:10.1002/ptr.6370 · Cited by 79 · see citing works
Impact of curcumin on sirtuins: A review
Zendedel, E., Butler, A. E., Atkin, S. L., & Sahebkar, A. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27371 · Cited by 76 · see citing works
Self-citationHeat shock proteins and cardiovascular disease
Rodríguez‐Iturbe, B., & Johnson, R. (2018) · Physiology International · doi:10.1556/2060.105.2018.1.4 · Cited by 76 · see citing works
Curcumin as a therapeutic agent in leukemia
Kouhpeikar, H., Butler, A. E., Bamian, F., Barreto, G. E., Majeed, M. A., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28072 · Cited by 74 · see citing works
Self-citationNovel Therapeutic Delivery of Nanocurcumin in Central Nervous System Related Disorders
Panzarini, E., Mariano, S., Tacconi, S., Carata, E., Tata, A. M., & Dini, L. (2020) · Nanomaterials · doi:10.3390/nano11010002 · Cited by 74 · see citing works
Vascular endothelial growth factor: An important molecular target of curcumin
Saberi‐Karimian, M., Katsiki, N., Caraglia, M., Boccellino, M., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1366892 · Cited by 74 · see citing works
Self-citationSimental‐Mendía, L. E., Pirro, M., Gotto, A. M., Banach, M., Atkin, S. L., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1396201 · Cited by 72 · see citing works
Self-citationCurcumin: A Naturally Occurring Modulator of Adipokines in Diabetes
Hajavi, J., Momtazi‐Borojeni, A. A., Johnston, T. P., Banach, M., Majeed, M. A., & Sahebkar, A. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26121 · Cited by 71 · see citing works
Self-citationMultiple health benefits of curcumin and its therapeutic potential
Shah, M., Murad, W., Mubin, S., Ullah, O., Rehman, N. U., & Rahman, M. H. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-20137-w · Cited by 70 · see citing works
Therapeutic Effect of Curcumin on Metabolic Diseases: Evidence from Clinical Studies
Zeng, Y., Luo, Y., Wang, L., Zhang, K., Peng, J., & Fan, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043323 · Cited by 69 · see citing works
Curcumin and treatment of melanoma: The potential role of microRNAs
Lelli, D., Pedone, C., & Sahebkar, A. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.01.078 · Cited by 66 · see citing works
Self-citationProtective effects of curcumin against aflatoxicosis: A comprehensive review
Mohajeri, M., Behnam, B., Cicero, A. F. G., & Sahebkar, A. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.26212 · Cited by 61 · see citing works
Self-citationde Melo, I. S. V., dos Santos, A. F., & Bueno, N. B. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.09.010 · Cited by 60 · see citing works
Curcuma longa, the Polyphenolic Curcumin Compound and Pharmacological Effects on Liver
Tùng, B. T., Nham, D. T., Hải, N. T., & Thu, D. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814466-4.00010-0 · Cited by 59 · see citing works
Naturally occurring anti-cancer agents targeting EZH2
Shahabipour, F., Caraglia, M., Majeed, M. A., Derosa, G., Maffioli, P., & Sahebkar, A. (2017) · Cancer Letters · doi:10.1016/j.canlet.2017.03.020 · Cited by 57 · see citing works
Self-citationCheng, M., Ding, F., Li, L., Dai, C., Sun, X., Xu, J., Chen, F., Li, M., & Li, X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1517174 · Cited by 49 · see citing works
Rodrigues, H. C. N., Martins, T. F. P., Silva-Santana, N. C. F. E., Braga, C. C., Silva, M. A. C., da Cunha, L. C., Sugizaki, C. S. D. A., Freitas, A. T. V. D. S., Costa, N. A., & Peixoto, M. D. R. G. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.06.006 · Cited by 47 · see citing works
Teymouri, M., Barati, N., Pirro, M., & Sahebkar, A. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25749 · Cited by 46 · see citing works
Self-citationCurrent Status of Obesity: Protective Role of Catechins
Basu, T., Selman, A., Reddy, A. P., & Reddy, P. H. (2023) · Antioxidants · doi:10.3390/antiox12020474 · Cited by 45 · see citing works
Ghazimoradi, M., Saberi‐Karimian, M., Mohammadi, F., Sahebkar, A., Tavallaie, S., Safarian, H., Ferns, G. A., Ghayour‐Mobarhan, M., Moohebati, M., Esmaily, H., et al. (2017) · Phytotherapy Research · doi:10.1002/ptr.5899 · Cited by 44 · see citing works
Self-citationLiang, H., Huang, C., Chou, C.-W., Makondi, P. T., Huang, M., Wei, P., & Chang, Y. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.07.047 · Cited by 44 · see citing works
A State of the Art of Antioxidant Properties of Curcuminoids in Neurodegenerative Diseases
Silvestro, S., Sindona, C., Bramanti, P., & Mazzon, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22063168 · Cited by 43 · see citing works
Singletary, K. W. (2020) · Nutrition Today · doi:10.1097/nt.0000000000000392 · Cited by 41 · see citing works
Evaluation of the effects of curcumin in patients with metabolic syndrome
Saberi‐Karimian, M., Parizadeh, S. M. R., Ghayour‐Mobarhan, M., Salahshooh, M. M., Dizaji, B. F., Safarian, H., Javandoost, A., Ferns, G. A., Sahebkar, A., & Ahmadinejad, M. (2018) · Comparative Clinical Pathology · doi:10.1007/s00580-017-2624-y · Cited by 38 · see citing works
Self-citationThe molecular mechanisms of curcumin’s inhibitory effects on cancer stem cells
Zendedel, E., Abdollahi, E., Momtazi‐Borojeni, A. A., Korani, M., Alavizadeh, S. H., & Sahebkar, A. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27757 · Cited by 35 · see citing works
Self-citationSahoo, J. P., Behera, L., Praveena, J., Sawant, S., Mishra, A., Sharma, S. S., Ghosh, L., Mishra, A. P., Sahoo, A. R., Pradhan, P., et al. (2021) · American Journal of Plant Sciences · doi:10.4236/ajps.2021.123030 · Cited by 35 · see citing works
Park, H.-J., & Lee, H.-S. (2016) · Nutrition Research and Practice · doi:10.4162/nrp.2016.10.4.418 · Cited by 34 · see citing works
Ocular Effects of Sulfur Mustard and Therapeutic Approaches
Panahi, Y., Rajaee, S. M., & Sahebkar, A. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25892 · Cited by 34 · see citing works
Self-citationEffects of Curcumin on Serum Vitamin E Concentrations in Individuals with Metabolic Syndrome
Mohammadi, A., Sadeghnia, H. R., Saberi‐Karimian, M., Safarian, H., Ferns, G. A., Ghayour‐Mobarhan, M., & Sahebkar, A. (2017) · Phytotherapy Research · doi:10.1002/ptr.5779 · Cited by 34 · see citing works
Self-citationMakori, W. A., Kibiti, C. M., Njagi, J. M., & Ngugi, M. P. (2019) · Journal of Evidence-Based Integrative Medicine · doi:10.1177/2515690x19883258 · Cited by 34 · see citing works
Heat Shock Proteins and Cardiovascular Disease
Zilaee, M., Ferns, G. A., & Ghayour-Mobarhan, M. (2014) · Advances in clinical chemistry · doi:10.1016/b978-0-12-800263-6.00002-1 · Cited by 33 · see citing works
Self-citationOptimized curcumin formulations for the treatment of Alzheimer's disease: A patent evaluation
Shakeri, A., & Sahebkar, A. (2015) · Journal of Neuroscience Research · doi:10.1002/jnr.23696 · Cited by 33 · see citing works
Self-citationEffect of Curcumin on Anthropometric Measures: A Systematic Review on Randomized Clinical Trials
Hariri, M., & Haghighatdoost, F. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2017.1392263 · Cited by 33 · see citing works
Sun, C.-B., Yi, Y., Qin-Yi, W., Liu, Y., Yu, J., Xing, H., Si-Qi, Z., Jiong, H., Jing, W., Liu, F., et al. (2020) · Molecular Immunology · doi:10.1016/j.molimm.2020.05.017 · Cited by 30 · see citing works
Recent updates on clinical developments of curcumin and its derivatives
Joshi, P., Bisht, A., Paliwal, A., Dwivedi, J., & Sharma, S. K. (2023) · Phytotherapy Research · doi:10.1002/ptr.7974 · Cited by 30 · see citing works
On the health effects of curcumin and its derivatives
Ayub, H., Islam, M., Saeed, M., Ahmad, H., Al‐Asmari, F., Ramadan, M. F., Alissa, M., Arif, M. A., Rana, M. U. J., Subtain, M., et al. (2024) · Food Science & Nutrition · doi:10.1002/fsn3.4469 · Cited by 29 · see citing works
Vukajlović, J. M., Drakulić, D., Pejić, S., Petković, M., Ilic, T. V., Miljković, M., Stefanović, A., Prostran, M. S., & Stojanov, M. (2017) · International Journal of Neuroscience · doi:10.1080/00207454.2017.1403916 · Cited by 27 · see citing works
- Authors
- Sahebkar, A., Mohammadi, A., Atabati, A., Rahiman, S., Tavallaie, S., Iranshahi, M., Akhlaghi, S., Ferns, G. A., & Ghayour‐Mobarhan, M.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- Islamic Azad University, Mashhad (IR)
- Brighton and Sussex Medical School (GB)
- Corresponding author
- Iranshahi, Mehrdad
- Ghayour‐Mobarhan, Majid
- Venue
- Phytotherapy Research
- Publisher
- Wiley
- Published
- 2013-03-15
- Volume
- 27
- Issue
- 12
- Pages
- 1883-1888
- ISSN
- 0951-418X (ISSN-L)
- 1099-1573
- OpenAlex
- W2171479615
- Cited by
- 183
- References
- 58
- Citations by year
- 2026: 9 · 2025: 19 · 2024: 8 · 2023: 13 · 2022: 9 · 2021: 18 · 2020: 9 · 2019: 13 · 2018: 15 · 2017: 24 · 2016: 22 · 2015: 9 · 2014: 12 · 2013: 3
- FWCI
- 7.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Phytotherapy Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Curcumin's Biomedical Applications
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- curcuminoids, prooxidant-antioxidant balance, oxidative stress, obesity, HSP27, oxidized LDL, antibody titers, immune response, dietary supplementation, antioxidant activity
- MeSH terms
- Adult, Antibodies, Antioxidants, Curcumin, Double-Blind Method, Female, Heat-Shock Proteins, Humans, Lipoproteins, LDL, Male, Middle Aged, Obesity, Oxidants, Reactive Oxygen Species, Oxidative Stress, Cross-Over Studies, Molecular Chaperones, Dietary Supplements, HSP27 Heat-Shock Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
