Effects of curcumin on HDL functionality

Ganjali, Shiva; Blesso, Christopher N.; Banach, Maciej; Pirro, Matteo; Majeed, Muhammed; Sahebkar, Amirhossein

doi:10.1016/j.phrs.2017.02.008

Cited by 186Curcumin's Biomedical ApplicationsParaoxonase enzyme and polymorphismsNatural Products and Biological Research

Effects of curcumin on HDL functionality

Open access

Ganjali, Shiva, Blesso, Christopher N., Banach, Maciej, Pirro, Matteo, Majeed, Muhammed, Sahebkar, Amirhossein·2017·Pharmacological Research

DOI 10.1016/j.phrs.2017.02.008

Open this paper in CoChat — free account

Abstract

Curcumin, a bioactive polyphenol, is a yellow pigment of the Curcuma longa (turmeric) plant. Curcumin has many pharmacologic effects including antioxidant, anti-carcinogenic, anti-obesity, anti-angiogenic and anti-inflammatory properties. Recently, it has been found that curcumin affects lipid metabolism, and subsequently, may alleviate hyperlipidemia and atherosclerosis. Plasma HDL cholesterol (HDL-C) is an independent negative risk predictor of cardiovascular disease (CVD). However, numerous clinical and genetic studies have yielded disappointing results about the therapeutic benefit of raising plasma HDL-C levels. Therefore, research efforts are now focused on improving HDL functionality, independent of HDL-C levels. The quality of HDL particles can vary considerably due to heterogeneity in composition. Consistent with its complexity in composition and metabolism, a wide range of biological activities is reported for HDL, including antioxidant, anti-glycation, anti-inflammatory, anti-thrombotic, anti-apoptotic and immune modulatory activities. Protective properties of curcumin may influence HDL functionality; therefore, we reviewed the literature to determine whether curcumin can augment HDL function. In this review, we concluded that curcumin may modulate markers of HDL function, such as apo-AI, CETP, LCAT, PON1, MPO activities and levels. Curcumin may subsequently improve conditions in which HDL is dysfunctional and may have potential as a therapeutic drug in future. Further clinical trials with bioavailability-improved formulations of curcumin are warranted to examine its effects on lipid metabolism and HDL function.

Integrity signals

Registry

Crossref · 10.1016/j.phrs.2017.02.008

Cites

126 of 126 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Curcumin may modulate HDL production and HDL functionality biomarkers, including apolipoprotein AI, cholesteryl ester transfer protein, lecithin cholesterol acyl transferase, paraoxonase-1, myeloperoxidase, and lipoprotein-associated phospholipase A2.
“Curcumin may also modulate the production of HDL and biomarkers of HDL functionality, including apolipoprotein AI ([), cholesteryl ester transfer protein (Y), lecithin cholesterol acyl transferase ([), paraoxonase-1 (Y), myeloperoxidase (Y), and lipoprotein-associated phospholipase A2 (Y) (174-177).”
From The Role of Nutraceuticals in Statin Intolerant Patients (2018) · cites this paper as [174]

Bioavailability of curcumin: Problems and promises
Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007) · Molecular Pharmaceutics · doi:10.1021/mp700113r · Cited by 5,543 · see citing works
High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.
Gordon, D. J., Probstfield, J. L., Garrison, R. J., Neaton, J. D., Castelli, W. P., Knoke, J. D., Jacobs, D. R., Bangdiwala, S., & Tyroler, H. A. (1989) · Circulation · doi:10.1161/01.cir.79.1.8 · Cited by 3,162 · see citing works
Effects of torcetrapib in patients at high risk for coronary events
Barter, P. J., Caulfield, M., Eriksson, M., Grundy, S. M., Kastelein, J. J. P., Komajda, M., Lopez-Sendon, J., Mosca, L., Tardif, J.-C., Waters, D. D., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706628 · Cited by 3,139 · see citing works
Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy
The AIM-HIGH Investigators (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1107579 · Cited by 2,911 · see citing works
Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
Acton, S. L., Rigotti, A., Landschulz, K. T., Xu, S., Hobbs, H. H., & Krieger, M. (1996) · Science · doi:10.1126/science.271.5248.518 · Cited by 2,347 · see citing works
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
Khera, A. V., Cuchel, M., de la Llera-Moya, M., Rodrigues, A., Burke, M. F., Jafri, K., French, B. C., Phillips, J. A., Mucksavage, M. L., Wilensky, R. L., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1001689 · Cited by 1,943 · see citing works
Effects of extended-release niacin with laropiprant in high-risk patients
The HPS2-THRIVE Collaborative Group (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1300955 · Cited by 1,668 · see citing works
Molecular physiology of reverse cholesterol transport.
Fielding, C. J., & Fielding, P. E. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39898-9 · Cited by 1,448 · see citing works
HDL cholesterol efflux capacity and incident cardiovascular events
Rohatgi, A., Khera, A., Berry, J. D., Givens, E. G., Ayers, C. R., Wedin, K. E., Neeland, I. J., Yuhanna, I. S., Rader, D. R., de Lemos, J. A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409065 · Cited by 1,390 · see citing works
MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
Rayner, K. J., Suárez, Y., Dávalos, A., Parathath, S., Fitzgerald, M. L., Tamehiro, N., Fisher, E. A., Moore, K. J., & Fernández-Hernando, C. (2010) · Science · doi:10.1126/science.1189862 · Cited by 1,260 · see citing works
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
Vaisar, T., Pennathur, S., Green, P. S., Gharib, S. A., Hoofnagle, A. N., Cheung, M. C., Byun, J., Vuletic, S., Kassim, S., Singh, P., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci26206 · Cited by 942 · see citing works
Novel insights of dietary polyphenols and obesity
Wang, S. F., Moustaïd‐Moussa, N., Chen, L., Mo, H., Shastri, A. A., Su, R., Bapat, P., Kwun, I., & Shen, C. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.09.001 · Cited by 903 · see citing works
Foam cells in atherosclerosis
Yu, X.-H., Fu, Y., Zhang, D., Yin, K., & Tang, C. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2013.06.006 · Cited by 772 · see citing works
Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies
Mirzaei, H., Shakeri, A., Rashidi, B., Jalili, A., Banikazemi, Z., & Sahebkar, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.11.098 · Cited by 519 · see citing works
Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial
Rahmani, S., Asgary, S., Askari, G., Keshvari, M., Hatamipour, M., Feizi, A., & Sahebkar, A. (2016) · Phytotherapy Research · doi:10.1002/ptr.5659 · Cited by 462 · see citing works
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport
Bergt, C., Pennathur, S., Fu, X., Byun, J., O'Brien, K., McDonald, T. O., Singh, P., Anantharamaiah, G. M., Chait, A., Brunzell, J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405292101 · Cited by 454 · see citing works
Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition.
Coetzee, G. A., Strachan, A. F., van der Westhuyzen, D. R., Hoppe, H., Jeenah, M. S., & de Beer, F. C. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67562-3 · Cited by 426 · see citing works
Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis
Panahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Majeed, M. A., & Sahebkar, A. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2014.12.019 · Cited by 407 · see citing works
Inflammation Impairs Reverse Cholesterol Transport In Vivo
McGillicuddy, F. C., Moya, M. D. L. L., Hinkle, C. C., Joshi, M. R., Chiquoine, E. H., Billheimer, J. T., Rothblat, G. H., & Reilly, M. P. (2009) · Circulation · doi:10.1161/circulationaha.108.810721 · Cited by 392 · see citing works
The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages
de la Llera-Moya, M., Drazul‐Schrader, D., Asztalos, B. F., Cuchel, M., Rader, D. J., & Rothblat, G. H. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.199158 · Cited by 385 · see citing works
A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids
Navab, M., Hama, S. Y., Hough, G. P., Subbanagounder, G., Reddy, S. T., & Fogelman, A. M. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31582-0 · Cited by 334 · see citing works
The roles of different pathways in the release of cholesterol from macrophages
Adorni, M. P., Zimetti, F., Billheimer, J. T., Wang, N., Rader, D. J., Phillips, M. C., & Rothblat, G. H. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700274-jlr200 · Cited by 332 · see citing works
Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial
Panahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Simental‐Mendía, L. E., Majeed, M. A., & Sahebkar, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.05.037 · Cited by 329 · see citing works
Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles
Mackness, M., & Mackness, B. (2015) · Gene · doi:10.1016/j.gene.2015.04.088 · Cited by 310 · see citing works
Are Curcuminoids Effective C-Reactive Protein-Lowering Agents in Clinical Practice? Evidence from a Meta-Analysis
Sahebkar, A. (2013) · Phytotherapy Research · doi:10.1002/ptr.5045 · Cited by 304 · see citing works
Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials
Sahebkar, A., Cicero, A. F. G., Simental‐Mendía, L. E., Aggarwal, B. B., & Gupta, S. C. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.03.026 · Cited by 295 · see citing works
The protective role of curcumin in cardiovascular diseases
Wongcharoen, W., & Phrommintikul, A. (2009) · International Journal of Cardiology · doi:10.1016/j.ijcard.2009.01.073 · Cited by 293 · see citing works
Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial
Panahi, Y., Kianpour, P., Mohtashami, R., Jafari, R., Simental‐Mendía, L. E., & Sahebkar, A. (2017) · Drug Research · doi:10.1055/s-0043-100019 · Cited by 288 · see citing works
Effects of Supplementation with Curcuminoids on Dyslipidemia in Obese Patients: A Randomized Crossover Trial
Mohammadi, A., Sahebkar, A., Iranshahi, M., Amini, M., Khojasteh, R., Ghayour‐Mobarhan, M., & Ferns, G. A. (2012) · Phytotherapy Research · doi:10.1002/ptr.4715 · Cited by 277 · see citing works
Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?
Abdollahi, E., Momtazi‐Borojeni, A. A., Johnston, T. P., & Sahebkar, A. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25778 · Cited by 271 · see citing works
Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial
Panahi, Y., Kianpour, P., Mohtashami, R., Jafari, R., Simental‐Mendía, L. E., & Sahebkar, A. (2016) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000406 · Cited by 269 · see citing works
Curcumin use in pulmonary diseases: State of the art and future perspectives
Lelli, D., Sahebkar, A., Johnston, T. P., & Pedone, C. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.11.017 · Cited by 259 · see citing works
Long‐term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism
Shin, S., Ha, T., McGregor, R. A., & Choi, M. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100440 · Cited by 257 · see citing works
Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat–fed hamsters
Jang, E.-M., Choi, M., Jung, U. J., Kim, M., Kim, H.-J., Jeon, S.-M., Shin, S., Seong, C.-N., & Lee, M. (2008) · Metabolism · doi:10.1016/j.metabol.2008.06.014 · Cited by 251 · see citing works
Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people
DiSilvestro, R. A., Joseph, E., Zhao, S., & Bomser, J. A. (2012) · Nutrition Journal · doi:10.1186/1475-2891-11-79 · Cited by 244 · see citing works
Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver
Eck, M. V., Twisk, J., Hoekstra, M., Rij, B. T. V., van der Lans, C. A. C., Bos, I. S. T., Kruijt, J. K., Kuipers, F., & van Berkel, T. J. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211233200 · Cited by 238 · see citing works
Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial
Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Karimian, M. S., Majeed, M. A., & Sahebkar, A. (2016) · Inflammopharmacology · doi:10.1007/s10787-016-0301-4 · Cited by 238 · see citing works
Lipid-modifying effects of adjunctive therapy with curcuminoids–piperine combination in patients with metabolic syndrome: Results of a randomized controlled trial
Panahi, Y., Khalili, N., Hosseini, M. S., Abbasinazari, M., & Sahebkar, A. (2014) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2014.07.006 · Cited by 231 · see citing works
Curcumin as a MicroRNA Regulator in Cancer: A Review
Momtazi‐Borojeni, A. A., Shahabipour, F., Khatibi, S., Johnston, T. P., Pirro, M., & Sahebkar, A. (2016) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/112_2016_3 · Cited by 230 · see citing works
Mitigation of Systemic Oxidative Stress by Curcuminoids in Osteoarthritis: Results of a Randomized Controlled Trial
Panahi, Y., Alishiri, G. H., Parvin, S., & Sahebkar, A. (2015) · Journal of Dietary Supplements · doi:10.3109/19390211.2015.1008611 · Cited by 229 · see citing works
The role of dysfunctional HDL in atherosclerosis
Navab, M., Reddy, S. T., Lenten, B. J. V., Anantharamaiah, G. M., & Fogelman, A. M. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800036-jlr200 · Cited by 222 · see citing works
Effect of Curcumin on Serum and Liver Cholesterol Levels in the Rat
Rao, D. S. V. S., Sekhara, N. C., Satyanarayana, M. N., & Srinivasan, M. (1970) · Journal of Nutrition · doi:10.1093/jn/100.11.1307 · Cited by 214 · see citing works
Investigation of the Effects of Curcumin on Serum Cytokines in Obese Individuals: A Randomized Controlled Trial
Ganjali, S., Sahebkar, A., Mahdipour, E., Jamialahmadi, K., Torabi, S., Akhlaghi, S., Ferns, G. A., Parizadeh, S. M. R., & Ghayour‐Mobarhan, M. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/898361 · Cited by 211 · see citing works
Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity
Vaisar, T., Tang, C., Babenko, I. M., Hutchins, P. M., Wimberger, J., Suffredini, A. F., & Heinecke, J. W. (2015) · Journal of Lipid Research · doi:10.1194/jlr.m059089 · Cited by 210 · see citing works
Dysfunctional HDL: A novel important diagnostic and therapeutic target in cardiovascular disease?
Otocka-Kmiecik, A., Mikhailidis, D. P., Nicholls, S. J., Davidson, M. H., Rysz, J., & Banach, M. (2012) · Progress in Lipid Research · doi:10.1016/j.plipres.2012.03.003 · Cited by 205 · see citing works
Curcumin as a natural regulator of monocyte chemoattractant protein-1
Karimian, M. S., Pirro, M., Majeed, M. A., & Sahebkar, A. (2016) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2016.10.001 · Cited by 196 · see citing works
High density lipoproteins: Measurement techniques and potential biomarkers of cardiovascular risk
Hafiane, A., & Genest, J. J. (2015) · BBA Clinical · doi:10.1016/j.bbacli.2015.01.005 · Cited by 195 · see citing works
An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial
Esmaily, H., Sahebkar, A., Iranshahi, M., Ganjali, S., Mohammadi, A., Ferns, G. A., & Ghayour‐Mobarhan, M. (2015) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-015-2160-z · Cited by 194 · see citing works
Curcumin as a multifaceted compound against human papilloma virus infection and cervical cancers: A review of chemistry, cellular, molecular, and preclinical features
Teymouri, M., Pirro, M., Johnston, T. P., & Sahebkar, A. (2016) · BioFactors · doi:10.1002/biof.1344 · Cited by 193 · see citing works
Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial
Panahi, Y., Ghanei, M., Hajhashemi, A., & Sahebkar, A. (2014) · Journal of Dietary Supplements · doi:10.3109/19390211.2014.952865 · Cited by 192 · see citing works
Curcumin: An Effective Inhibitor of Interleukin-6
Ghandadi, M., & Sahebkar, A. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666161006151605 · Cited by 192 · see citing works
Investigation of the Efficacy of Adjunctive Therapy with Bioavailability‐Boosted Curcuminoids in Major Depressive Disorder
Panahi, Y., Badeli, R., Karami, G., & Sahebkar, A. (2014) · Phytotherapy Research · doi:10.1002/ptr.5211 · Cited by 187 · see citing works
Antioxidant Paraoxonase 1 Activity in the Metabolic Syndrome
Sentı́, M., Tomás, M., Fitó, M., Weinbrenner, T., Covas, M., Sala, J., Masià, R., & Marrugat, J. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030648 · Cited by 186 · see citing works
Effect of statin therapy on paraoxonase-1 status: A systematic review and meta-analysis of 25 clinical trials
Ferretti, G., Bacchetti, T., & Sahebkar, A. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.08.003 · Cited by 184 · see citing works
Curcuminoids Modulate Pro‐Oxidant–Antioxidant Balance but not the Immune Response to Heat Shock Protein 27 and Oxidized LDL in Obese Individuals
Sahebkar, A., Mohammadi, A., Atabati, A., Rahiman, S., Tavallaie, S., Iranshahi, M., Akhlaghi, S., Ferns, G. A., & Ghayour‐Mobarhan, M. (2013) · Phytotherapy Research · doi:10.1002/ptr.4952 · Cited by 183 · see citing works
Self-citation
Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials
Derosa, G., Maffioli, P., Simental‐Mendía, L. E., Bo, S., & Sahebkar, A. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.07.004 · Cited by 180 · see citing works
Role of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases
Momtazi‐Borojeni, A. A., Derosa, G., Maffioli, P., Banach, M., & Sahebkar, A. (2016) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-016-0202-7 · Cited by 179 · see citing works
A randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complications
Panahi, Y., Sahebkar, A., Parvin, S., & Saadat, A. (2012) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012040 · Cited by 176 · see citing works
Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity
Rezaee, R., Momtazi‐Borojeni, A. A., Monemi, A., & Sahebkar, A. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.12.037 · Cited by 176 · see citing works
Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial
Panahi, Y., Sahebkar, A., Amiri, M., Davoudi, S. M., Beiraghdar, F., Hoseininejad, S. L., & Kolivand, M. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511006544 · Cited by 175 · see citing works
Analgesic Efficacy and Safety of Curcuminoids in Clinical Practice: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Sahebkar, A., & Henrotin, Y. E. (2015) · Pain Medicine · doi:10.1093/pm/pnv024 · Cited by 174 · see citing works
Curcuminoids for the management of hypertriglyceridaemia
Sahebkar, A. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2013.140-c1 · Cited by 172 · see citing works
Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome?
Sahebkar, A. (2012) · BioFactors · doi:10.1002/biof.1062 · Cited by 171 · see citing works
Myeloperoxidase Targets Apolipoprotein A-I, the Major High Density Lipoprotein Protein, for Site-Specific Oxidation in Human Atherosclerotic Lesions
Shao, B., Pennathur, S., & Heinecke, J. W. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.337345 · Cited by 170 · see citing works
Molecular mechanisms for curcumin benefits against ischemic injury
Sahebkar, A. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.07.1071 · Cited by 168 · see citing works
Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo
Iranshahi, M., Sahebkar, A., Hosseini, S. T., Takasaki, M., Konoshima, T., & Tokuda, H. (2009) · Phytomedicine · doi:10.1016/j.phymed.2009.05.020 · Cited by 164 · see citing works
Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes
Shen, S. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i13.1953 · Cited by 162 · see citing works
Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial
Panahi, Y., Ghanei, M., Bashiri, S., Hajihashemi, A., & Sahebkar, A. (2014) · Drug Research · doi:10.1055/s-0034-1389986 · Cited by 158 · see citing works
Curcumin induces changes in expression of genes involved in cholesterol homeostasis
Peschel, D., Koerting, R., & Naß, N. (2006) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2006.03.007 · Cited by 152 · see citing works
Thermal stability, antioxidant, and anti-inflammatory activity of curcumin and its degradation product 4-vinyl guaiacol
Esatbeyoglu, T., Ulbrich, K., Rehberg, C., Rohn, S., & Rimbach, G. H. (2015) · Food & Function · doi:10.1039/c4fo00790e · Cited by 152 · see citing works
Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis
Zhao, J., Ching, L., Huang, Y., Chen, C., Chiang, A., Kou, Y. R., Shyue, S., & Lee, T. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100735 · Cited by 152 · see citing works
HDL functionality
Soran, H., Hama, S., Yadav, R., & Durrington, P. N. (2012) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328355ca25 · Cited by 150 · see citing works
Reciprocal and Coordinate Regulation of Serum Amyloid A Versus Apolipoprotein A-I and Paraoxonase-1 by Inflammation in Murine Hepatocytes
Han, C. Y., Chiba, T., Campbell, J. S., Fausto, N., Chaisson, M. L., Orasanu, G., Plutzky, J., & Chait, A. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000227472.70734.ad · Cited by 140 · see citing works
Lipoprotein carriers of microRNAs
Michell, D. L., & Vickers, K. C. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.01.011 · Cited by 135 · see citing works
The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis
Masson, D., Jiang, X., Lagrost, L., & Tall, A. R. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800061-jlr200 · Cited by 134 · see citing works
Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I
Collet, X., Tall, A. R., Serajuddin, H., Guendouzi, K., Royer, L. J., Oliveira, H. C. F., Barbaras, R., Jiang, X., & Francone, O. L. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)33480-5 · Cited by 131 · see citing works
Regulation of Cellular Cholesterol Efflux by Lecithin:Cholesterol Acyltransferase Reaction through Nonspecific Lipid Exchange
Czarnecka, H., & Yokoyama, S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.4.2023 · Cited by 124 · see citing works
Minimal Lipidation of Pre-β HDL by ABCA1 Results in Reduced Ability to Interact with ABCA1
Mulya, A., Lee, J., Gebre, A. K., Thomas, M. J., Colvin, P. L., & Parks, J. S. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.142455 · Cited by 113 · see citing works
Effects of supplementation with curcumin on serum adipokine concentrations: A randomized controlled trial
Panahi, Y., Hosseini, M. S., Khalili, N., Naimi, E., Soflaei, S. S., Majeed, M. A., & Sahebkar, A. (2016) · Nutrition · doi:10.1016/j.nut.2016.03.018 · Cited by 106 · see citing works
Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits
Lenten, B. J. V., Wagner, A. C., Navab, M., Anantharamaiah, G. M., Hama, S. Y., Reddy, S. T., & Fogelman, A. M. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700138-jlr200 · Cited by 103 · see citing works
HDL endocytosis and resecretion
Röhrl, C., & Stangl, H. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.07.014 · Cited by 100 · see citing works
HDL-S1P: cardiovascular functions, disease-associated alterations, and therapeutic applications
Levkau, B. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00243 · Cited by 98 · see citing works
Mitochondrial ATP synthase activity is impaired by suppressed<i>O</i>-GlcNAcylation in Alzheimer's disease
Cha, M.-Y., Cho, H. J., Kim, C., Jung, Y. O., Kang, M. J., Murray, M. E., Hong, H. S., Choi, Y.-J., Choi, H., Kim, D. K., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv358 · Cited by 95 · see citing works
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway
Huang, J., Huang, K., Lan, T., Xie, X., Shen, X., Liu, P., & Huang, H. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.10.024 · Cited by 91 · see citing works
Analgesic efficacy and safety of curcuminoids in clinical practice: A systematic review and meta-analysis of randomized controlled trials
Henrotin, Y. E., & Sahebkar, A. (2015) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2015.02.657 · Cited by 91 · see citing works
MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2
Zhang, P., Bai, H., Liu, G., Wang, H., Chen, F., Zhang, B., Zeng, P., Wu, C., Peng, C., Huang, C., et al. (2015) · Toxicology Letters · doi:10.1016/j.toxlet.2015.02.018 · Cited by 89 · see citing works
An hydroalcoholic extract of Curcuma longa lowers the apo B/apo A ratio
Ramírez-Boscá, A., Soler, A., Carrión, M. A., Dı́az-Alperi, J., Bernd, A., Quintanilla, C., Almagro, E. Q., & Miquel, J. (2000) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(00)00169-x · Cited by 87 · see citing works
Curcumin Enhanced Cholesterol Efflux by Upregulating ABCA1 Expression Through AMPK-SIRT1-LXRα Signaling in THP-1 Macrophage-Derived Foam Cells
Lin, X., Liu, M., Hu, H.-J., Feng, H., Fan, X., Zou, W.-W., Pan, Y., Hu, X., & Wang, Z. (2015) · DNA and Cell Biology · doi:10.1089/dna.2015.2866 · Cited by 86 · see citing works
Is There a Role for Curcumin Supplementation in the Treatment of Non-Alcoholic Fatty Liver Disease? The Data Suggest Yes
Zabihi, N. A., Pirro, M., Johnston, T. P., & Sahebkar, A. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666161010115235 · Cited by 85 · see citing works
Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis
Chen, F., Zhou, J., Guo, N., Ma, W., Huang, X. S., Wang, H., & Yuan, Z. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.10.051 · Cited by 82 · see citing works
HDL‐paraoxonase and Membrane Lipid Peroxidation: A Comparison Between Healthy and Obese Subjects
Ferretti, G., Bacchetti, T., Masciangelo, S., & Bicchiega, V. (2009) · Obesity · doi:10.1038/oby.2009.338 · Cited by 79 · see citing works
Dual effect of curcumin in preventing atherosclerosis: the potential role of pro-oxidant–antioxidant mechanisms
Sahebkar, A. (2014) · Natural Product Research · doi:10.1080/14786419.2014.956212 · Cited by 69 · see citing works
Curcumin promotes cholesterol efflux from adipocytes related to PPARgamma–LXRalpha–ABCA1 passway
Dong, S.-Z., Zhao, S., Wu, Z., Yang, J., Xie, X.-Z., Yu, B., & Nie, S. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-0978-z · Cited by 69 · see citing works
Sphingosine Kinase-1 Pathway Mediates High Glucose-Induced Fibronectin Expression in Glomerular Mesangial Cells
Lan, T., Liu, W., Xie, X. S., Xu, S., Huang, K., Peng, J., Shen, X., Liu, P., Wang, L., Xia, P., et al. (2011) · Molecular Endocrinology · doi:10.1210/me.2011-0095 · Cited by 67 · see citing works
Emerging therapies for raising high-density lipoprotein cholesterol (HDL-C) and augmenting HDL particle functionality
Barylski, M., Toth, P. P., Nikolic, D., Banach, M., Rizzo, M., & Montalto, G. (2014) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.11.001 · Cited by 67 · see citing works
Self-citation
Increased Oxidative Stress in Scavenger Receptor BI Knockout Mice With Dysfunctional HDL
Eck, M. V., Hoekstra, M., Hildebrand, R. B., Yaong, Y., Stengel, D., Kruijt, J. K., Sattler, W., Tietge, U. J. F., Ninio, E., van Berkel, T. J. C., et al. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.145474 · Cited by 66 · see citing works
Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial disease
Pasqualini, L., Cortese, C., Marchesi, S., Siepi, D., Pirro, M., Vaudo, G., Liberatoscioli, L., Gnasso, A., Schillaci, G., & Mannarino, E. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.03.030 · Cited by 65 · see citing works
Nicotinate-Curcumin Impedes Foam Cell Formation from THP-1 Cells through Restoring Autophagy Flux
Gu, H., Li, H., Tang, Y., Tang, X., Zheng, X., & Liao, D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154820 · Cited by 62 · see citing works
Modulation of cAMP levels by high‐fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression
Zingg, J.-M. A., Hasan, S. T., Nakagawa, K., Canepa, E., Ricciarelli, R., Villacorta, L., Azzi, A., & Meydani, M. (2016) · BioFactors · doi:10.1002/biof.1307 · Cited by 55 · see citing works
Molecular docking studies of curcumin analogs with phospholipase A2
Dileep, K. V., Tintu, I., & Sadasivan, C. (2011) · Interdisciplinary Sciences Computational Life Sciences · doi:10.1007/s12539-011-0090-9 · Cited by 51 · see citing works
Modeling studies on phospholipase A2-inhibitor complexes.
Nithya, N., Praba, G. O., & Velmurugan, D. (2008) · PubMed · Cited by 51 · see citing works
Curcumin inhibits cell growth and induces cell apoptosis through upregulation of miR-33b in gastric cancer
Sun, Q., Zhang, W., Guo, Y., Li, Z., Chen, X., Wang, Y., Du, Y., Zang, W., & Zhao, G. (2016) · Tumor Biology · doi:10.1007/s13277-016-5221-9 · Cited by 49 · see citing works
Curcumin inhibits monocyte chemoattractant protein-1 expression and enhances cholesterol efflux by suppressing the c-Jun N-terminal kinase pathway in macrophage
Liu, T., Li, C., Sun, H., Luo, T., Tan, Y., Tian, D., & Guo, Z. (2014) · Inflammation Research · doi:10.1007/s00011-014-0758-9 · Cited by 48 · see citing works
Protective Role of Dietary Curcumin in the Prevention of the Oxidative Stress Induced by Chronic Alcohol with respect to Hepatic Injury and Antiatherogenic Markers
Varatharajalu, R., Garige, M., Leckey, L. C., Reyes‐Gordillo, K., Shah, R., & Lakshman, M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5017460 · Cited by 47 · see citing works
Atheroprotective potentials of curcuminoids against ginger extract in hypercholesterolaemic rabbits
Elseweidy, M. M., Younis, N. N., El-Swefy, S. E., Abdallah, F. R., El-Dahmy, S., Elnagar, G. M., & Kassem, H. M. (2014) · Natural Product Research · doi:10.1080/14786419.2014.957699 · Cited by 45 · see citing works
Piperine potentiates the hypocholesterolemic effect of curcumin in rats fed on a high fat diet
Tu, Y. S., Sun, D., Zeng, X., YAO, N., Huang, X., Huang, D., & Yuxing, C. (2014) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2014.1717 · Cited by 40 · see citing works
ROSIGLITAZONE MODULATES FASTING AND POST‐PRANDIAL PARAOXONASE 1 ACTIVITY IN TYPE 2 DIABETIC PATIENTS
van Wijk, J. P. H., Coll, B., Cabezas, M. C., de Koning, E. J. P., Camps, J., Rabelink, T. J., Mackness, B., & Joven, J. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04505.x · Cited by 38 · see citing works
Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats
Leray, V., Freuchet, B., Bloc’h, J. L., Jeusette, I. C., Torre, C., & Nguyen, P. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002492 · Cited by 37 · see citing works
Curcumin Induces ABCA1 Expression and Apolipoprotein A-I-Mediated Cholesterol Transmembrane in the Chronic Cerebral Hypoperfusion Aging Rats
Tian, M., Zhang, X., Wang, L., & Li, Y. (2013) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x13500699 · Cited by 33 · see citing works
Lipid-Regulating Effect of Traditional Chinese Medicine: Mechanisms of Actions
Bei, W., Guo, J., Wu, H., & Cao, Y. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/970635 · Cited by 31 · see citing works
Effects of Curcuma xanthorrhiza Roxb. and curcuminoids on the level of serum and liver lipids, serum apolipoprotein A-I and lipogenic enzymes in rats
Yasni, S., Imaizumi, K., Nakamura, M., Aimoto, J., & SUGANO, M. (1993) · Food and Chemical Toxicology · doi:10.1016/0278-6915(93)90096-h · Cited by 30 · see citing works
Plasma C-reactive protein in subjects with hypo/hyperalphalipoproteinemias
Pirro, M., Siepi, D., Lupattelli, G., Roscini, A. R., Schillaci, G., Gemelli, F., Vaudo, G., Marchesi, S., Pasqualini, L., & Mannarino, E. (2003) · Metabolism · doi:10.1053/meta.2003.50072 · Cited by 30 · see citing works
Curcumin induces paraoxonase 1 in cultured hepatocytes in vitro but not in mouse liver in vivo
Schrader, C., Schiborr, C., Frank, J., & Rimbach, G. H. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510004356 · Cited by 28 · see citing works
Subfractions of high-density lipoprotein (HDL) and dysfunctional HDL in chronic kidney disease patients
Rysz-Górzyńska, M., & Banach, M. (2016) · Archives of Medical Science · doi:10.5114/aoms.2016.60971 · Cited by 25 · see citing works
Can We Change the Functionality of HDL Cholesterol with Nonpharmacological and Pharmacological Agents?
Dragan, S. R., Șerban, M.-C., & Banach, M. (2014) · Current Medicinal Chemistry · doi:10.2174/0929867321666140303153829 · Cited by 21 · see citing works
Protective effect of curcumin on chloroform as by-product of water chlorination induced cardiotoxicity
Salama, A. F., Tousson, E., Shalaby, K. A., & Hussien, H. T. (2014) · Biomedicine & Preventive Nutrition · doi:10.1016/j.bionut.2014.02.004 · Cited by 20 · see citing works
Systematic review and meta-analysis deciphering the impact of fibrates on paraoxonase-1 status
Sahebkar, A., Hernández‐Aguilera, A., Abelló, D., Sancho, E., Camps, J., & Joven, J. (2016) · Metabolism · doi:10.1016/j.metabol.2016.01.002 · Cited by 20 · see citing works
In vivoeffects of curcumin on the paraoxonase, carbonic anhydrase, glucose-6-phosphate dehydrogenase andβ-glucosidase enzyme activities in dextran sulphate sodium-induced ulcerative colitis mice
Yıldırım, H., Sunay, F. B., Sinan, S., & KOCKAR, F. T. (2016) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2016.1158173 · Cited by 18 · see citing works
The Protective Effect of Curcumin on Myocardial Ischemia-Reperfusion Injury
Kim, Y. S., Park, H. J., Joo, S. Y., Hong, M. H., Kim, K. H., Hong, Y. J., Kim, J. H., Park, H. W., Jeong, M. H., Cho, J. G., et al. (2008) · Korean Circulation Journal · doi:10.4070/kcj.2008.38.7.353 · Cited by 15 · see citing works
Role of Curcumin in Modulating Plasma PON1 Arylesterase Activity and Susceptibility to LDL Oxidation in Oxidatively Challenged Wistar Rats
Singh, P., & Rizvi, S. I. (2015) · Letters in Drug Design & Discovery · doi:10.2174/1570180811666141016000539 · Cited by 14 · see citing works
Protective effect of curcumin on priapism and ischemia-reperfusion injury in rats.
Yılmaz, Y., Taken, K., Atar, M. A., Ergün, M., & Söylemez, H. (2015) · PubMed · Cited by 11 · see citing works
On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: Impact on carotid intima-media thickness
Pirro, M., Vaudo, G., Lupattelli, G., Pasqualini, L., Mannarino, M. R., Schillaci, G., Alaeddin, A., Paciullo, F., Fallarino, F., Bagaglia, F., et al. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.07.008 · Cited by 9 · see citing works
Modulatory Effect of Phytoestrogens and Curcumin on Induction of Annexin 1 in Human Peripheral Blood Mononuclear Cells and their Inhibitory Effect on Secretory Phospholipase A2
Ahmad, W., Kumolosasi, E., Jantan, I., Jasamai, M., & Salim, E. (2014) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v13i2.1 · Cited by 7 · see citing works
The use of curcumin in obstructive jaundice
Karatepe, O., Gülçiçek, O. B., Adaş, G., Battal, M., Kamali, G. H., Kemık, A. S., Altuğ, T., & Karahan, S. (2009) · Archives of Medical Science · Cited by 6 · see citing works
Advances in Dyslipidemia
Aronow, W. S. (2013) · doi:10.2217/9781780843308 · Cited by 3 · see citing works
Effets métaboliques du Curcumin (obésité, lipides circulants, insulinorésistance, diabète et athérosclérose)
Lecerf, J. M. (2012) · Phytothérapie · doi:10.1007/s10298-012-0694-1 · Cited by 2 · see citing works

Flagged first, then by citations

7 of the 133 references couldn’t be matched to a known paper.

Sorted by citations

Turmeric ( Curcuma longa ) and its major constituent (curcumin) as nontoxic and safe substances: Review
Soleimani, V., Sahebkar, A., & Hosseinzadeh, H. (2018) · Phytotherapy Research · doi:10.1002/ptr.6054 · Cited by 556 · see citing works
Cellular and molecular mechanisms of curcumin in prevention and treatment of disease
Patel, S. S., Acharya, A., Ray, R. S., Agrawal, R. K., Raghuwanshi, R., & Jain, P. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1552244 · Cited by 518 · see citing works
Immune modulation by curcumin: The role of interleukin-10
Mollazadeh, H., Cicero, A. F. G., Blesso, C. N., Pirro, M., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1358139 · Cited by 382 · see citing works
Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy
Mortezaee, K., Salehi, E., Mirtavoos‐Mahyari, H., Motevaseli, E., Najafi, M., Farhood, B., Rosengren, R. J., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28122 · Cited by 342 · see citing works
The Role of Nutraceuticals in Statin Intolerant Patients
Banach, M., Patti, A. M., Giglio, R. V., Cicero, A. F. G., Atanasov, A. G., Bajraktari, G., Bruckert, E., Descamps, O., Djuric, D. M., Ezhov, M., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.04.040 · Cited by 272 · see citing works
Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy
Farhood, B., Mortezaee, K., Goradel, N. H., Khanlarkhani, N., Salehi, E., Nashtaei, M. S., Najafi, M., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27442 · Cited by 248 · see citing works
Effects of Curcuminoids Plus Piperine on Glycemic, Hepatic and Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind Placebo-Controlled Trial
Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Simental‐Mendía, L. E., Majeed, M. A., & Sahebkar, A. (2018) · Drug Research · doi:10.1055/s-0044-101752 · Cited by 236 · see citing works
Curcumin: A naturally occurring autophagy modulator
Shakeri, A., Cicero, A. F. G., Panahi, Y., Mohajeri, M., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27404 · Cited by 228 · see citing works
Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent
Mohammadi, A., Blesso, C. N., Barreto, G. E., Banach, M., Majeed, M. A., & Sahebkar, A. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.12.005 · Cited by 226 · see citing works
Medicinal plants and bioactive natural compounds in the treatment of non-alcoholic fatty liver disease: A clinical review
Bagherniya, M., Nobili, V., Blesso, C. N., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.12.020 · Cited by 225 · see citing works
Evidence of curcumin and curcumin analogue effects in skin diseases: A narrative review
Panahi, Y., Fazlolahzadeh, O., Atkin, S. L., Majeed, M. A., Butler, A. E., Johnston, T. P., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27096 · Cited by 222 · see citing works
Curcuminoids modify lipid profile in type 2 diabetes mellitus: A randomized controlled trial
Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Reiner, Ž., Majeed, M. A., & Sahebkar, A. (2017) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2017.05.006 · Cited by 222 · see citing works
Curcumin, hemostasis, thrombosis, and coagulation
Keihanian, F., Saeidinia, A., Bagheri, R. K., Johnston, T. P., & Sahebkar, A. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.26249 · Cited by 220 · see citing works
The regulation and importance of monocyte chemoattractant protein-1
Bianconi, V., Sahebkar, A., Atkin, S. L., & Pirro, M. (2017) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000389 · Cited by 219 · see citing works
Curcumin nanofibers for the purpose of wound healing
Fereydouni, N., Darroudi, M., Movaffagh, J., Shahroodi, A., Butler, A. E., Ganjali, S., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27362 · Cited by 197 · see citing works
Management of Statin Intolerance in 2018: Still More Questions Than Answers
Toth, P. P., Patti, A. M., Giglio, R. V., Nikolić, D., Castellino, G., Rizzo, M., & Banach, M. (2018) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-017-0259-7 · Cited by 188 · see citing works
Curcumin‐piperine co‐supplementation and human health: A comprehensive review of preclinical and clinical studies
Heidari, H., Bagherniya, M., Majeed, M. A., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2023) · Phytotherapy Research · doi:10.1002/ptr.7737 · Cited by 184 · see citing works
The versatile role of curcumin in cancer prevention and treatment: A focus on PI3K/AKT pathway
Hamzehzadeh, L., Atkin, S. L., Majeed, M. A., Butler, A. E., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26620 · Cited by 172 · see citing works
Targeted inhibition of STAT3 as a potential treatment strategy for atherosclerosis
Chen, Q., Lv, J., Yang, W., Xu, B., Wang, Z., Yu, Z., Wu, J., Yang, Y., & Han, Y. (2019) · Theranostics · doi:10.7150/thno.35528 · Cited by 170 · see citing works
Therapeutic use of curcumin‐encapsulated and curcumin‐primed exosomes
Nosrati‐Oskouie, M., Aghili‐Moghaddam, N. S., Butler, A. E., Zamani, P., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27615 · Cited by 162 · see citing works
Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Sadeghi, M., Dehnavi, S., Asadirad, A., Xu, S., Majeed, M. A., Jamialahmadi, T., Johnston, T. P., & Sahebkar, A. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01136-w · Cited by 163 · see citing works
Recent Molecular Mechanisms and Beneficial Effects of Phytochemicals and Plant-Based Whole Foods in Reducing LDL-C and Preventing Cardiovascular Disease
Islam, S. U., Ahmed, M. B., Ahsan, H., & Lee, Y. S. (2021) · Antioxidants · doi:10.3390/antiox10050784 · Cited by 140 · see citing works
Regulation of PCSK9 by nutraceuticals
Momtazi, A. A., Banach, M., Pirro, M., Katsiki, N., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.023 · Cited by 131 · see citing works
Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System
Bavarsad, K., Barreto, G. E., Hadjzadeh, M., & Sahebkar, A. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1169-7 · Cited by 115 · see citing works
Magnetic-Silk Core–Shell Nanoparticles as Potential Carriers for Targeted Delivery of Curcumin into Human Breast Cancer Cells
Song, W., Muthana, M., Mukherjee, J., Falconer, R. J., Biggs, C. A., & Zhao, X. (2017) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.7b00153 · Cited by 108 · see citing works
High density lipoprotein cholesterol and cancer: Marker or causative?
Pirro, M., Ricciuti, B., Rader, D. J., Catapano, A. L., Sahebkar, A., & Banach, M. (2018) · Progress in Lipid Research · doi:10.1016/j.plipres.2018.06.001 · Cited by 107 · see citing works
Hormetic effects of curcumin: What is the evidence?
Moghaddam, N. S. A., Oskouie, M. N., Butler, A., Petit, P., Barreto, G., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27880 · Cited by 103 · see citing works
Bioactive compounds from herbal medicines to manage dyslipidemia
Ji, X., Shi, S., Liu, B., Shan, M., Tang, D., Zhang, W., Zhang, Y., Zhang, L., Zhang, H., Lu, C. C., et al. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109338 · Cited by 104 · see citing works
Curcuminoids plus piperine improve nonalcoholic fatty liver disease: A clinical trial
Panahi, Y., Valizadegan, G., Ahamdi, N., Ganjali, S., Majeed, M. A., & Sahebkar, A. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28877 · Cited by 100 · see citing works
Effects of Curcumin on Microglial Cells
Ghasemi, F., Bagheri, H., Barreto, G. E., Read, M. I., & Sahebkar, A. (2019) · Neurotoxicity Research · doi:10.1007/s12640-019-00030-0 · Cited by 97 · see citing works
Choosing the appropriate wall materials for spray-drying microencapsulation of natural bioactive ingredients: Taking phenolic compounds as examples
Lu, W., Yang, X. H., Shen, J., Li, Z., Tan, S., Liu, W., & Cheng, Z. (2021) · Powder Technology · doi:10.1016/j.powtec.2021.08.082 · Cited by 96 · see citing works
Synergistic effects of liposomes encapsulating atorvastatin calcium and curcumin and targeting dysfunctional endothelial cells in reducing atherosclerosis
Li, M., Xiao, H. P., Lin, C., Sun, W., Wu, T., Wang, J., Chen, B., Chen, X., & Cheng, D. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s189819 · Cited by 92 · see citing works
Polymeric nanomicelles of curcumin: Potential applications in cancer
Farhoudi, L., Kesharwani, P., Majeed, M. A., Johnston, T. P., & Sahebkar, A. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121622 · Cited by 89 · see citing works
Anti-Angiogenic Activity of Curcumin in Cancer Therapy: A Narrative Review
Shakeri, A., Ward, N. C., Panahi, Y., & Sahebkar, A. (2018) · Current Vascular Pharmacology · doi:10.2174/1570161116666180209113014 · Cited by 85 · see citing works
Potential therapeutic effects of curcumin in gastric cancer
Barati, N., Momtazi‐Borojeni, A. A., Majeed, M. A., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27229 · Cited by 83 · see citing works
The effects of curcumin supplementation on liver function, metabolic profile and body composition in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials
Jalali, M., Mahmoodi, M., Mosallanezhad, Z., Jalali, R., Imanieh, M. H., & Moosavian, S. P. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.102283 · Cited by 82 · see citing works
Effects of phytochemicals on macrophage cholesterol efflux capacity: Impact on atherosclerosis
Soltani, S., Boozari, M., Cicero, A. F. G., Jamialahmadi, T., & Sahebkar, A. (2021) · Phytotherapy Research · doi:10.1002/ptr.6991 · Cited by 81 · see citing works
High-Density Lipoprotein Components and Functionality in Cancer: State-of-the-Art
Ganjali, S., Ricciuti, B., Pirro, M., Butler, A. E., Atkin, S. L., Banach, M., & Sahebkar, A. (2018) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2018.10.004 · Cited by 77 · see citing works
Impact of curcumin on sirtuins: A review
Zendedel, E., Butler, A. E., Atkin, S. L., & Sahebkar, A. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27371 · Cited by 76 · see citing works
Demethoxycurcumin: A naturally occurring curcumin analogue for treating non‐cancerous diseases
Hatamipour, M., Ramezani, M., Tabassi, S. A. S., Johnston, T. P., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28626 · Cited by 76 · see citing works
Curcumin as a therapeutic agent in leukemia
Kouhpeikar, H., Butler, A. E., Bamian, F., Barreto, G. E., Majeed, M. A., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28072 · Cited by 74 · see citing works
Polyphenols and Their Role in Obesity Management: A Systematic Review of Randomized Clinical Trials
Farhat, G., Drummond, S., & Al‐Dujaili, E. A. S. (2017) · Phytotherapy Research · doi:10.1002/ptr.5830 · Cited by 74 · see citing works
Vascular endothelial growth factor: An important molecular target of curcumin
Saberi‐Karimian, M., Katsiki, N., Caraglia, M., Boccellino, M., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1366892 · Cited by 74 · see citing works
Protective effects of curcumin against ischemia-reperfusion injury in the liver
Bavarsad, K., Riahi, M. M., Saadat, S., Barreto, G. E., Atkin, S. L., & Sahebkar, A. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.12.014 · Cited by 74 · see citing works
Effect of nano‐curcumin on various diseases: A comprehensive review of clinical trials
Hassanizadeh, S., Shojaei, M., Bagherniya, M., Orekhov, A. N., & Sahebkar, A. (2023) · BioFactors · doi:10.1002/biof.1932 · Cited by 73 · see citing works
Lipid-modifying activity of curcuminoids: A systematic review and meta-analysis of randomized controlled trials
Simental‐Mendía, L. E., Pirro, M., Gotto, A. M., Banach, M., Atkin, S. L., Majeed, M. A., & Sahebkar, A. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1396201 · Cited by 72 · see citing works
Curcumin - A promising nutritional strategy for chronic kidney disease patients
Alvarenga, L., Leal, V. D. O., Borges, N. A., de Aguiar, A. S., Irving, G. F., Stenvinkel, P., Lindholm, B., & Mafra, D. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.12.015 · Cited by 71 · see citing works
Curcumin: A Naturally Occurring Modulator of Adipokines in Diabetes
Hajavi, J., Momtazi‐Borojeni, A. A., Johnston, T. P., Banach, M., Majeed, M. A., & Sahebkar, A. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26121 · Cited by 71 · see citing works
Impact of curcumin on toll‐like receptors
Boozari, M., Butler, A. E., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28103 · Cited by 71 · see citing works
Botanicals and phytochemicals active on cognitive decline: The clinical evidence
Cicero, A. F. G., Fogacci, F., & Banach, M. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.12.029 · Cited by 70 · see citing works
Curcumin: a potent agent to reverse epithelial-to-mesenchymal transition
Bahrami, A., Majeed, M. A., & Sahebkar, A. (2019) · Cellular Oncology · doi:10.1007/s13402-019-00442-2 · Cited by 69 · see citing works
Add-on Treatment with Curcumin Has Antidepressive Effects in Thai Patients with Major Depression: Results of a Randomized Double-Blind Placebo-Controlled Study
Kanchanatawan, B., Tangwongchai, S., Sughondhabhirom, A., Suppapitiporn, S., Hemrunrojn, S., Carvalho, A. F., & Maes, M. H. J. (2018) · Neurotoxicity Research · doi:10.1007/s12640-017-9860-4 · Cited by 71 · see citing works
Recent advances in nanogold as a promising nanocarrier for curcumin delivery
Mahmoudi, A. A., Kesharwani, P., Majeed, M. A., Teng, Y., & Sahebkar, A. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112481 · Cited by 64 · see citing works
Inhibitory effects of phytochemicals on NLRP3 inflammasome activation: A review
Olcum, M., Tastan, B., Ercan, İ., Eltutan, B. I., & Genç, Ş. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153238 · Cited by 63 · see citing works
Effects of curcumin on hypoxia-inducible factor as a new therapeutic target
Bahrami, A., Atkin, S. L., Majeed, M. A., & Sahebkar, A. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.10.009 · Cited by 63 · see citing works
Effects of turmeric (Curcuma longa) and its constituent (curcumin) on the metabolic syndrome: An updated review
Vafaeipour, Z., Razavi, B. M., & Hosseinzadeh, H. (2022) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2022.02.008 · Cited by 62 · see citing works
The potential role of plant-derived natural products in improving arterial stiffness: A review of dietary intervention studies
Alidadi, M., Jamialahmadi, T., Cicero, A. F. G., Bianconi, V., Pirro, M., Banach, M., & Sahebkar, A. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.03.026 · Cited by 60 · see citing works
JAK/STAT3 signaling in cardiac fibrosis: a promising therapeutic target
Jiang, H., Yang, J., Li, T., Wang, X., Fan, Z., Ye, Q., & Du, Y. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1336102 · Cited by 61 · see citing works
Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets
Ghanaatian, N., Lashgari, N., Abdolghaffari, A. H., Rajaee, S. M., Panahi, Y., Barreto, G. E., Butler, A. E., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27965 · Cited by 60 · see citing works
Therapeutic Potential of Polyphenols-Loaded Polymeric Nanoparticles in Cardiovascular System
Pecháňová, O., Dayar, E., & Cebová, M. (2020) · Molecules · doi:10.3390/molecules25153322 · Cited by 63 · see citing works
Anti-atherosclerosis of oligomeric proanthocyanidins from Rhodiola rosea on rat model via hypolipemic, antioxidant, anti-inflammatory activities together with regulation of endothelial function
Zhou, Q., Han, X., Li, R., Zhao, W., Bai, B., Yan, C., & Dong, X. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.10.002 · Cited by 56 · see citing works
Antitumor effects of curcumin: A lipid perspective
Naeini, M. B., Momtazi‐Borojeni, A. A., Jaafari, M. R., Johnston, T. P., Barreto, G. E., Banach, M., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28262 · Cited by 57 · see citing works
Natural products with anti-inflammatory and immunomodulatory activities against autoimmune myocarditis
Javadi, B., & Sahebkar, A. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.07.022 · Cited by 54 · see citing works
Anticancer potential of curcumin-cyclodextrin complexes and their pharmacokinetic properties
Shahriari, M., Kesharwani, P., Johnston, T. P., & Sahebkar, A. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.122474 · Cited by 53 · see citing works
Chitosan‐based delivery systems for curcumin: A review of pharmacodynamic and pharmacokinetic aspects
Saheb, M., Fereydouni, N., Nemati, S., Barreto, G. E., Johnston, T. P., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28024 · Cited by 53 · see citing works
Therapeutic Potential of Curcumin in the Treatment of Glioblastoma Multiforme
Shahcheraghi, S. H., Zangui, M., Lotfi, M., Ghayour‐Mobarhan, M., Ghorbani, A., Jaliani, H. Z., Sadeghnia, H. R., & Sahebkar, A. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190313123704 · Cited by 51 · see citing works
Consumption of Cuban Policosanol Improves Blood Pressure and Lipid Profile via Enhancement of HDL Functionality in Healthy Women Subjects: Randomized, Double‐Blinded, and Placebo‐Controlled Study
Cho, K., Kim, S., Yadav, D., Kim, J., & Kim, J. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/4809525 · Cited by 50 · see citing works
Demethoxycurcumin: A naturally occurring curcumin analogue with antitumor properties
Hatamipour, M., Ramezani, M., Tabassi, S. A. S., Johnston, T. P., Ramezani, M., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27029 · Cited by 49 · see citing works
Gefitinib and curcumin-loaded nanoparticles enhance cell apoptosis in human oral cancer SAS cells in vitro and inhibit SAS cell xenografted tumor in vivo
Lai, K., Chueh, F., Hsiao, Y.-T., Cheng, Z.-Y., Lien, J., Liu, K.-C., Peng, S., & Chung, J. (2019) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2019.114734 · Cited by 50 · see citing works
Reversal of Doxorubicin-induced Cardiotoxicity by Using Phytotherapy: A Review.
Hosseini, A., & Sahebkar, A. (2017) · Europe PMC (PubMed Central) · doi:10.3831/kpi.2017.20.030 · Cited by 49 · see citing works
An overview of the therapeutic effects of curcumin in reproductive disorders with a focus on the antiinflammatory and immunomodulatory activities
Saifi, B., Haftcheshmeh, S. M., Feligioni, M., Izadpanah, E., Rahimi, K., Hassanzadeh, K., Mohammadi, A., & Sahebkar, A. (2022) · Phytotherapy Research · doi:10.1002/ptr.7360 · Cited by 47 · see citing works
Protective effects of plant‐derived natural products on renal complications
Yaribeygi, H., Simental‐Mendía, L. E., Butler, A. E., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.27950 · Cited by 46 · see citing works
Curcumin in heart failure: A choice for complementary therapy?
Saeidinia, A., Keihanian, F., Butler, A. E., Bagheri, R. K., Atkin, S. L., & Sahebkar, A. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.03.009 · Cited by 46 · see citing works
Dietary natural products as emerging lipoprotein(a)‐lowering agents
Momtazi‐Borojeni, A. A., Katsiki, N., Pirro, M., Banach, M., Al‐Rasadi, K., & Sahebkar, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28134 · Cited by 46 · see citing works
Curcumin Inhibits ERK/c-Jun Expressions and Phosphorylation against Endometrial Carcinoma
Zhang, Z., Yi, P., Tu, C., Zhan, J., Jiang, L., & Zhang, F. (2019) · BioMed Research International · doi:10.1155/2019/8912961 · Cited by 45 · see citing works
Bioactive Compounds of Turmeric (Curcuma longa L.)
Filho, J. G. D. O., de Almeida, M. J., de Sousa, T. L., dos Santos, D. C., & Egea, M. B. (2021) · Reference series in phytochemistry · doi:10.1007/978-3-030-57415-4_37 · Cited by 44 · see citing works
Probiotics for the treatment of hyperlipidemia: Focus on gut-liver axis and lipid metabolism
You, M. S., Zhou, L., Wu, F., Zhang, L., Zhu, S.-X., & Zhang, H. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107694 · Cited by 44 · see citing works
Turmeric
Singletary, K. W. (2020) · Nutrition Today · doi:10.1097/nt.0000000000000392 · Cited by 41 · see citing works
Mechanism of NLRP3 inflammasome in epilepsy and related therapeutic agents.
Chen, J., Gao, Y., Liu, N., Hai, D., Wei, W., Liu, Y., Lan, X.-B., Jin, X., Yu, J.-Q., & Ma, L. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.03.029 · Cited by 37 · see citing works
Neuroprotective effects of antioxidants in the management of neurodegenerative disorders: A literature review
Panahi, Y., Rajaee, S. M., Johnston, T. P., & Sahebkar, A. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26536 · Cited by 39 · see citing works
Cholesterol-Lowering Nutraceuticals Affecting Vascular Function and Cardiovascular Disease Risk
Bianconi, V., Mannarino, M. R., Sahebkar, A., Cosentino, T., & Pirro, M. (2018) · Current Cardiology Reports · doi:10.1007/s11886-018-0994-7 · Cited by 39 · see citing works
Current evidence and future perspectives for curcumin and its analogues as promising adjuncts to oxaliplatin: state-of-the-art
Zangui, M., Atkin, S. L., Majeed, M. A., & Sahebkar, A. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.01.020 · Cited by 39 · see citing works
The Role of Chemokines in Cardiovascular Diseases and the Therapeutic Effect of Curcumin on CXCL8 and CCL2 as Pathological Chemokines in Atherosclerosis
Hedayati‐Moghadam, M., Hosseinian, S., Paseban, M., Shabgah, A. G., Navashenaq, J. G., Jamialahmadi, T., Sathyapalan, T., & Sahebkar, A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-73234-9_11 · Cited by 37 · see citing works
Efficacy of curcumin plus piperine co‐supplementation in moderate‐to‐high hepatic steatosis: A double‐blind, randomized, placebo‐controlled clinical trial
Sharifi, S., Bagherniya, M., Khoram, Z., Varzaneh, A. E., Atkin, S. L., Jamialahmadi, T., Sahebkar, A., & Askari, G. (2023) · Phytotherapy Research · doi:10.1002/ptr.7764 · Cited by 37 · see citing works
A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease
Sardou, H. S., Vosough, P. R., Abbaspour, M., Akhgari, A., Sathyapalan, T., & Sahebkar, A. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01140-0 · Cited by 36 · see citing works
Germination results in reduced allergenicity of peanut by degradation of allergens and resveratrol enrichment
Rao, H., Chen, C., Tian, Y., Li, Y., Gao, Y., Tao, S., & Xue, W. (2018) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2018.10.015 · Cited by 35 · see citing works
Effects of synbiotic consumption on lipid profile: a systematic review and meta-analysis of randomized controlled clinical trials
Hadi, A., Ghaedi, E., Khalesi, S., Pourmasoumi, M., & Arab, A. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02248-7 · Cited by 35 · see citing works
Targeting HDL in tumor microenvironment: New hope for cancer therapy
Zhao, T., Zhu, N., Shi, Y., Wang, Y., Zhang, C., Deng, C., Liao, D., & Li, Q. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30412 · Cited by 34 · see citing works
Reconfiguring Nature’s Cholesterol Accepting Lipoproteins as Nanoparticle Platforms for Transport and Delivery of Therapeutic and Imaging Agents
Chuang, S. T., Cruz, S., & Narayanaswami, V. (2020) · Nanomaterials · doi:10.3390/nano10050906 · Cited by 33 · see citing works
In Vitro and In Vivo Cardioprotective Effects of Curcumin against Doxorubicin-Induced Cardiotoxicity: A Systematic Review
Zhang, Q., & Wu, L. (2022) · Journal of Oncology · doi:10.1155/2022/7277562 · Cited by 33 · see citing works
Improved light and ultraviolet stability of curcumin encapsulated in emulsion gels prepared with corn starch, OSA-starch and whey protein isolate
Zhan, S., He, M., Wu, Y., & Ouyang, J. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.138803 · Cited by 32 · see citing works
Therapeutic Effect of Curcumin in Women with Polycystic Ovary Syndrome Receiving Metformin: A Randomized Controlled Trial
Sohrevardi, S. M., Heydari, B., Azarpazhooh, M. R., Teymourzadeh, M., Simental‐Mendía, L. E., Atkin, S. L., Sahebkar, A., & Karimi‐Zarchi, M. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-64872-5_9 · Cited by 32 · see citing works
Effects of silymarin supplementation on blood lipids: A systematic review and meta‐analysis of clinical trials
Mohammadi, H., Hadi, A., Arab, A., Moradi, S., & Rouhani, M. H. (2019) · Phytotherapy Research · doi:10.1002/ptr.6287 · Cited by 31 · see citing works
The U-Shaped Association of Non-High-Density Lipoprotein Cholesterol Levels With All-Cause and Cardiovascular Mortality Among Patients With Hypertension
Cheng, Q., Liu, X., Chen, C., Huang, Y., Feng, Y., & Chen, J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.707701 · Cited by 30 · see citing works
Dietary Strategies to Improve Cardiovascular Health: Focus on Increasing High-Density Lipoprotein Functionality
Stadler, J. T., & Marsche, G. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.761170 · Cited by 31 · see citing works
Investigation of the Effect of Curcumin on Protein Targets in NAFLD Using Bioinformatic Analysis
Mahmoudi, A. A., Butler, A. E., Majeed, M. A., Banach, M., & Sahebkar, A. (2022) · Nutrients · doi:10.3390/nu14071331 · Cited by 30 · see citing works
Curcuminoids Lower Plasma Leptin Concentrations: A Meta‐analysis
Atkin, S. L., Katsiki, N., Derosa, G., Maffioli, P., & Sahebkar, A. (2017) · Phytotherapy Research · doi:10.1002/ptr.5905 · Cited by 29 · see citing works
The pharmacological basis of the curcumin nutraceutical uses: an update
Canistro, D., Chiavaroli, A., Cicia, D., Cimino, F., Currò, D., Agli, M. D., Ferrante, C., Giovannelli, L., Leone, S., Martinelli, G., et al. (2021) · doi:10.36118/pharmadvances.2021.06 · Cited by 28 · see citing works
The U Shaped Relationship Between High-Density Lipoprotein Cholesterol and All-Cause or Cause-Specific Mortality in Adult Population
Huang, Y., Liu, X., Lo, K. K.-H., Liu, L., Yu, Y., Chen, C., Huang, J., Feng, Y., & Zhang, B. (2020) · Clinical Interventions in Aging · doi:10.2147/cia.s271528 · Cited by 27 · see citing works
Review on the Therapeutic Potential of Curcumin and its Derivatives on Glioma Biology
Mohamadian, M., Ahmadi, S. S., Bahrami, A., & Ferns, G. A. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03666-1 · Cited by 26 · see citing works

Curcumin as a novel approach in improving lipid profile: An umbrella meta-analysis
Musazadeh, V., Roshanravan, N., Mohammadizadeh, M., Kavyani, Z., Dehghan, P., & Mosharkesh, E. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.07.021 · Cited by 31 · see citing works
The Effect of Curcumin on HDL Cholesterol Uptake Capacity in Obese Individuals: A Pilot Study
Saberi‐Karimian, M., Nosrati, M., Orooji, A., Kazemi, T., Javandoost, A., Mohammadi, A. M., Ferns, G. A., Aghasizadeh, M., & Ghayour‐Mobarhan, M. (2021) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.22038/jctm.2021.58306.1336
Curcumin from turmeric is an extremely efficient agent in increasing cholesterol uptake by the liver cells
(2023) · Journal of Pharmaceutical Research · doi:10.33140/jpr.08.01.01
Functional Food and Bioactive Compounds on the Modulation of the Functionality of HDL-C: A Narrative Review
Luna-Castillo, K. P., Lin, S., Muñóz-Valle, J. F., Vizmanos-Lamotte, B., López-Quintero, A., & Márquez‐Sandoval, F. (2021) · Nutrients · doi:10.3390/nu13041165 · Cited by 23 · see citing works
Curcumin and blood lipid levels: an updated systematic review and meta-analysis of randomised clinical trials
Saeedi, F., Farkhondeh, T., Roshanravan, B., Amirabadizadeh, A., Ashrafizadeh, M., & Samarghandian, S. (2020) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2020.1779309 · Cited by 24 · see citing works

Authors: Ganjali, S., Blesso, C. N., Banach, M., Pirro, M., Majeed, M., & Sahebkar, A.
Affiliations: Mashhad University of Medical Sciences (IR)
University of Connecticut (US)
Medical University of Lodz (PL)
University of Perugia (IT)
Corresponding author: Sahebkar, Amirhossein
ORCID: Ganjali, Shiva
Blesso, Christopher N.
Banach, Maciej
Pirro, Matteo
Majeed, Muhammed
Sahebkar, Amirhossein
Venue: Pharmacological Research
Publisher: Elsevier BV
Published: 2017-05
Volume: 119
Pages: 208-218
ISSN: 1043-6618 (ISSN-L)
DOI: 10.1016/j.phrs.2017.02.008
OpenAlex: W2586622953
Cited by: 186
References: 133
Citations by year: 2026: 6 · 2025: 19 · 2024: 8 · 2023: 24 · 2022: 20 · 2021: 16 · 2020: 11 · 2019: 27 · 2018: 35 · 2017: 20
FWCI: 1.64
Type: journal article
Language: en
Open access: green
figshare.com
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Pharmacological Research (publishedVersion)
PubMed (publishedVersion)
UWA Profiles and Research Repository (UWA) (submittedVersion)
Figshare (submittedVersion, cc-by)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Curcumin's Biomedical Applications
Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
Health Sciences › Medicine › Surgery › Natural Products and Biological Research
Keywords: curcumin, HDL function, HDL cholesterol, HDL dysfunction, apolipoprotein A-I, cholesteryl ester transfer protein, lecithin:cholesterol acyltransferase, paraoxonase 1, myeloperoxidase, lipid metabolism, hyperlipidemia, atherosclerosis, cardiovascular disease, polyphenols, bioavailability
MeSH terms: Animals, Anti-Inflammatory Agents, Non-Steroidal, Antioxidants, Curcumin, Humans, Lipoproteins, HDL, Curcuma, Dyslipidemias, Atherosclerosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effects of curcumin on HDL functionality

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks