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Cited by 376

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Methods for dealing with time‐dependent confounding

Daniel, R.M., Cousens, S.N., De Stavola, B.L., Kenward, M. G., Sterne, J. A. C.·2013·Statistics in Medicine

Abstract

Longitudinal studies, where data are repeatedly collected on subjects over a period, are common in medical research. When estimating the effect of a time‐varying treatment or exposure on an outcome of interest measured at a later time, standard methods fail to give consistent estimators in the presence of time‐varying confounders if those confounders are themselves affected by the treatment. Robins and colleagues have proposed several alternative methods that, provided certain assumptions hold, avoid the problems associated with standard approaches. They include the g‐computation formula, inverse probability weighted estimation of marginal structural models and g‐estimation of structural nested models. In this tutorial, we give a description of each of these methods, exploring the links and differences between them and the reasons for choosing one over the others in different settings. Copyright © 2012 John Wiley & Sons, Ltd.

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Metadata

Authors
Daniel, R. M., Cousens, S. N., De Stavola, B. L., Kenward, M. G., & Sterne, J. A. C.
Venue
Statistics in Medicine
Publisher
Wiley
Published
2012-12-03
Volume
32
Issue
9
Pages
1584-1618
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
OpenAlex
W2159198921
Cited by
376
References
10
FWCI
11.09
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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