The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Rattle‐Type Fe3O4@SiO2 Hollow Mesoporous Spheres as Carriers for Drug Delivery
Abstract
Rattle‐type Fe 3 O 4@SiO 2 hollow mesoporous spheres with different particle sizes, different mesoporous shell thicknesses, and different levels of Fe 3 O 4 content are prepared by using carbon spheres as templates. The effects of particle size and concentration of Fe 3 O 4@SiO 2 hollow mesoporous spheres on cell uptake and their in vitro cytotoxicity to HeLa cells are evaluated. The spheres exhibit relatively fast cell uptake. Concentrations of up to 150 µg mL−1 show no cytotoxicity, whereas a concentration of 200 µg mL−1 shows a small amount of cytotoxicity after 48 h of incubation. Doxorubicin hydrochloride (DOX), an anticancer drug, is loaded into the Fe 3 O 4@SiO 2 hollow mesoporous spheres, and the DOX‐loaded spheres exhibit a somewhat higher cytotoxicity than free DOX. These results indicate the potential of Fe 3 O 4@SiO 2 hollow mesoporous spheres for drug loading and delivery into cancer cells to induce cell death.
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Citations
Cites
Micellar Nanocarriers: Pharmaceutical Perspectives
Torchilin, V. P. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9132-0 · Cited by 1,910
Cited by
Wu, W., Wu, Z., Yu, T., Jiang, C., & Kim, W.-S. (2015) · Science and Technology of Advanced Materials · doi:10.1088/1468-6996/16/2/023501 · Cited by 1,574
Mesoporous silica nanoparticles in drug delivery and biomedical applications
Wang, Y., Zhao, Q., Han, N., Bai, L., Li, J., Liu, J., Che, E., Hu, L., Zhang, Q., Jiang, T., et al. (2015) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2014.09.014 · Cited by 1,192
Sol–gel based materials for biomedical applications
Owens, G. J., Singh, R. K., Foroutan, F., Alqaysi, M., Han, C.-M., Mahapatra, C., Kim, H.-W., & Knowles, J. C. (2016) · Progress in Materials Science · doi:10.1016/j.pmatsci.2015.12.001 · Cited by 958
Nguyen, M. D., Tran, H.-V., Xu, S., & Lee, T. R. (2021) · Applied Sciences · doi:10.3390/app112311301 · Cited by 783
Hollow‐Structured Mesoporous Materials: Chemical Synthesis, Functionalization and Applications
Li, Y., & Shi, J. (2014) · Advanced Materials · doi:10.1002/adma.201305319 · Cited by 759
Metadata
- Authors
- Zhu, Y., Ikoma, T., Hanagata, N., & Kaskel, S.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2010-01-27
- Volume
- 6
- Issue
- 3
- Pages
- 471-478
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W1968293067
- Cited by
- 375
- References
- 1
- FWCI
- 12.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhu, Y., Ikoma, T., Hanagata, N., & Kaskel, S. (2010). Rattle‐Type Fe3O4@SiO2 Hollow Mesoporous Spheres as Carriers for Drug Delivery. Small. https://doi.org/10.1002/smll.200901403
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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