The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
Abstract
The interactions of nanoparticles with the soft surfaces of biological systems like cells play key roles in executing their biomedical functions and in toxicity. The discovery or design of new biomedical functions, or the prediction of the toxicological consequences of nanoparticles in vivo, first require knowledge of the interplay processes of the nanoparticles with the target cells. This article focusses on the cellular uptake, location and translocation, and any biological consequences, such as cytotoxicity, of the most widely studied and used nanoparticles, such as carbon‐based nanoparticles, metallic nanoparticles, and quantum dots. The relevance of the size and shape, composition, charge, and surface chemistry of the nanoparticles in cells is considered. The intracellular uptake pathways of the nanoparticles and the cellular responses, with potential signaling pathways activated by nanoparticle interactions, are also discussed.
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Cites
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Cited by
Danaei, M., Dehghankhold, M., Ataei, S., Hasanzadeh Davarani, F., Javanmard, R., Dokhani, A., Khorasani, S., & Mozafari, M. R. (2018) · Pharmaceutics · doi:10.3390/pharmaceutics10020057 · Cited by 4,832
Cellular uptake of nanoparticles: Journey inside the cell
Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., Brown, D., Alkilany, A. M., Farokhzad, O. C., & Mahmoudi, M. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00636a · Cited by 2,859
Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Foroozandeh, P., & Aziz, A. A. (2018) · Nanoscale Research Letters · doi:10.1186/s11671-018-2728-6 · Cited by 1,377
Physicochemical Properties Determine Nanomaterial Cellular Uptake, Transport, and Fate
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Self-citationPolymeric Nanostructures for Imaging and Therapy
Elsabahy, M., Heo, G. S., Lim, S.-M., Sun, G., & Wooley, K. L. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00135 · Cited by 508
Metadata
- Authors
- Zhao, F., Zhao, Y., Liu, Y., Chang, X., Chen, C., & Zhao, Y.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2011-04-26
- Volume
- 7
- Issue
- 10
- Pages
- 1322-1337
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W1993373375
- Cited by
- 1,175
- References
- 8
- FWCI
- 29.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhao, F., Zhao, Y., Liu, Y., Chang, X., Chen, C., & Zhao, Y. (2011). Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials. Small. https://doi.org/10.1002/smll.201100001
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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