Maternal Exposure Causes Mitochondrial Dysfunction in Brain, Liver, and Heart of Mouse Fetus: An Explanation for Perfluorooctanoic Acid Induced Abortion and Developmental Toxicity

Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings

Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620 · see citing works

Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

Olsen, G. W., Burris, J. M., Ehresman, D. J., Froehlich, J. W., Seacat, A. M., Butenhoff, J. L., & Zobel, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10009 · Cited by 2,049 · see citing works

Mitochondria: Dynamic Organelles in Disease, Aging, and Development

Chan, D. C. (2006) · Cell · doi:10.1016/j.cell.2006.06.010 · Cited by 1,987 · see citing works

Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature

Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639 · see citing works

The Role of Mitochondrial Function in the Oocyte and Embryo

Dumollard, R., Duchen, M. R., & Carroll, J. (2007) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(06)77002-8 · Cited by 531 · see citing works

Neonatal Exposure to Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA) Causes Neurobehavioural Defects in Adult Mice

Johansson, N., Fredriksson, A., & Eriksson, P. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2007.10.008 · Cited by 463 · see citing works

Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease

Nissanka, N., & Moraes, C. T. (2017) · FEBS Letters · doi:10.1002/1873-3468.12956 · Cited by 453 · see citing works

Perfluorooctane Sulfonate in Fish-Eating Water Birds Including Bald Eagles and Albatrosses

Kannan, K., Franson, J. C., Bowerman, W. W., Hansen, K. J., Jones, P. D., & Giesy, J. P. (2001) · Environmental Science & Technology · doi:10.1021/es001935i · Cited by 304 · see citing works

The role of mitochondrial function and cellular bioenergetics in ageing and disease

Brand, M. D., Orr, A. L., Perevoshchikova, I. V., & Quinlan, C. L. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12208 · Cited by 292 · see citing works

Mitochondrial distribution and function in oocytes and early embryos

Bavister, B. D., & Squirrell, J. M. (2000) · Human Reproduction · doi:10.1093/humrep/15.suppl_2.189 · Cited by 285 · see citing works

Exposure to Polyfluoroalkyl Chemicals and Attention Deficit/Hyperactivity Disorder in U.S. Children 12–15 Years of Age

Hoffman, K., Webster, T. F., Weisskopf, M. G., Weinberg, J., & Vieira, V. M. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.1001898 · Cited by 262 · see citing works

Serum Levels of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and Pregnancy Outcome

Stein, C. R., Savitz, D. A., & Dougan, M. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp212 · Cited by 262 · see citing works

Carryover of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) from Soil to Plant and Distribution to the Different Plant Compartments Studied in Cultures of Carrots (Daucus carota ssp. Sativus), Potatoes (Solanum tuberosum), and Cucumbers (Cucumis Sativus)

Lechner, M., & Knapp, H. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf201355y · Cited by 225 · see citing works

Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures.

Wolf, C. J., Fenton, S., Schmid, J., Calafat, A., Kuklenyik, Z., Bryant, X. A., Thibodeaux, J. R., Das, K., White, S., Lau, C., et al. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl159 · Cited by 199 · see citing works

Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain

Khacho, M., & Slack, R. S. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24538 · Cited by 185 · see citing works

Extraction and clean-up strategies for the analysis of poly- and perfluoroalkyl substances in environmental and human matrices

van Leeuwen, S. P. J., & de Boer, J. (2007) · Journal of Chromatography A · doi:10.1016/j.chroma.2007.02.069 · Cited by 182 · see citing works

Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a High-throughput Targeted Metabolomics Approach

Yu, N., Wei, S., Li, M., Yang, J., Li, K., Jin, L. N., Xie, Y., Giesy, J. P., Zhang, X., & Yu, H. (2016) · Scientific Reports · doi:10.1038/srep23963 · Cited by 137 · see citing works

Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells

Blerkom, J. V. (2008) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60463-4 · Cited by 117 · see citing works

Nrf2- and PPARα-Mediated Regulation of Hepatic Mrp Transporters after Exposure to Perfluorooctanoic Acid and Perfluorodecanoic Acid

Maher, J. M., Aleksunes, L. M., Dieter, M. Z., Tanaka, Y., Peters, J. M., Manautou, J. E., & Klaassen, C. D. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn177 · Cited by 112 · see citing works

Locomotor behavior in zebrafish (Danio rerio) larvae exposed to perfluoroalkyl acids

Ulhaq, M., Örn, S., Carlsson, G., Morrison, D. A., & Norrgren, L. (2013) · Aquatic Toxicology · doi:10.1016/j.aquatox.2013.10.021 · Cited by 104 · see citing works

Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) – A comparison with lysosomotropic drugs

Garcia, D. S., Sjödin, M. O. D., Hellstrandh, M., Norinder, U., Nikiforova, V., Lindberg, J., Wincent, E., Bergman, Å., Cotgreave, I. A., & Kos, V. M. (2017) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.12.021 · Cited by 83 · see citing works

Perfluorooctanoic acid-induced hepatic toxicity following 21-day oral exposure in mice

Son, H., Kim, S.-H., Shin, H., Bae, H. I., & Yang, J. (2007) · Archives of Toxicology · doi:10.1007/s00204-007-0246-x · Cited by 79 · see citing works

Toxicity of cuprizone a Cu²⁺chelating agent on isolated mouse brain mitochondria: a justification for demyelination and subsequent behavioral dysfunction

Faizi, M., Salimi, A., Seydi, E., Naserzadeh, P., Kouhnavard, M., Rahimi, A., & Pourahmad, J. (2016) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2016.1172284 · Cited by 71 · see citing works

Mechanistic approach for the toxic effects of perfluorooctanoic acid on isolated rat liver and brain mitochondria

Mashayekhi, V., Tehrani, K. H. M. E., Hashemzaei, M., Tabrizian, K., Shahraki, J., & Hosseini, M.-J. (2015) · Human & Experimental Toxicology · doi:10.1177/0960327114565492 · Cited by 70 · see citing works

Effects of perfluorooctanoic acid (PFOA) exposure to pregnant mice on reproduction.

Yahia, D., el-Nasser, M. A., Abedel-Latif, M., Tsukuba, C., Yoshida, M., Sato, I., & Tsuda, S. (2010) · Journal of Toxicological Sciences · doi:10.2131/jts.35.527 · Cited by 67 · see citing works

Perflurooctanoic acid induces developmental cardiotoxicity in chicken embryos and hatchlings.

Jiang, Q.-X., Lust, R., Strynar, M., Dagnino, S., & DeWitt, J. (2012) · Toxicology · doi:10.1016/j.tox.2012.01.005 · Cited by 64 · see citing works

Attention deficit-hyperactivity disorder suffers from mitochondrial dysfunction

Verma, P., Singh, A., Nthenge-Ngumbau, D. N., Rajamma, U., Sinha, S., Mukhopadhyay, K., & Mohanakumar, K. P. (2016) · BBA Clinical · doi:10.1016/j.bbacli.2016.10.003 · Cited by 64 · see citing works

Mitochondria play an important role in the cell proliferation suppressing activity of berberine

Yan, X., Yu, X., Wang, X., Jiang, J.-F., Yuan, Z., Lü, X., Fan, L., & Xing, D. (2017) · Scientific Reports · doi:10.1038/srep41712 · Cited by 52 · see citing works

Neurobehavioral Teratogenicity of Perfluorinated Alkyls in an Avian Model

Pinkas, A., Slotkin, T. A., Brick-Turin, Y., Van der Zee, E. A., & Yanai, J. (2010) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2009.11.004 · Cited by 48 · see citing works

Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria

Seydi, E., Rasekh, H. R., Salimi, A., Mohsenifar, Z., & Pourahmad, J. (2016) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520616666160425110839 · Cited by 47 · see citing works

Toxicity of Atorvastatin on Pancreas Mitochondria: A Justification for Increased Risk of Diabetes Mellitus

Sadighara, M., Amirsheardost, Z., Minaiyan, M., Hajhashemi, V., Naserzadeh, P., Salimi, A., Seydi, E., & Pourahmad, J. (2016) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12656 · Cited by 45 · see citing works

Perfluorooctanoic acid induces mitochondrial dysfunction in MC3T3-E1 osteoblast cells

Choi, E. M., Suh, K. S., Rhee, S. Y., Oh, S., Woo, J., Kim, S. W., Kim, Y. S., Pak, Y. K., & Chon, S. (2016) · Journal of Environmental Science and Health Part A · doi:10.1080/10934529.2016.1253402 · Cited by 31 · see citing works

Perfluorooctanoic Acid Induced-Developmental Cardiotoxicity: Are Peroxisome Proliferator Activated Receptor α (PPARα) and Bone Morphorgenic Protein 2 (BMP2) Pathways Involved?

Jiang, Q., Lust, R. M., & DeWitt, J. C. (2013) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2013.789415 · Cited by 27 · see citing works

Embryo Toxic Effects of Atorvastatin on Mouse Fetus

Emami, F., Asl, B. M., Seydi, E., Zargar, M. A., Naserzadeh, P., & Pourahmad, J. (2013) · Iranian journal of pharmaceutical sciences · Cited by 6 · see citing works

Mitochondrial Dysfunction in Reproductive and Developmental Toxicity

Palmeira, C. M., & Ramalho‐Santos, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804239-7.00053-6 · Cited by 6 · see citing works

Measurement of Mitochondrial Toxicity Parameters in Embryonic Hippocampus

Salimi, A., & Pourahmad, J. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7883-0_31 · Cited by 3 · see citing works

A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior

Starnes, H. M., Rock, K. D., Jackson, T. W., & Belcher, S. M. (2022) · Frontiers in Toxicology · doi:10.3389/ftox.2022.881584 · Cited by 166 · see citing works

A Critical Review on Transplacental Transfer of Per- and Polyfluoroalkyl Substances: Prenatal Exposure Levels, Characteristics, and Mechanisms

Ma, D., Lü, Y., Liang, Y., Ruan, T., Li, J., Zhao, C., Wang, Y., & Jiang, G. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.1c01057 · Cited by 136 · see citing works

A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)

Wen, Z.-J., Wei, Y.-J., Zhang, Y., & Zhang, Y. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03477-5 · Cited by 109 · see citing works

PFAS and Potential Adverse Effects on Bone and Adipose Tissue through Interactions with PPARγ

Kirk, A. B., Michelsen-Correa, S., Rosen, C., Martin, C. F., & Blumberg, B. (2021) · Endocrinology · doi:10.1210/endocr/bqab194 · Cited by 90 · see citing works

Does Low Maternal Exposure to Per- and Polyfluoroalkyl Substances Elevate the Risk of Spontaneous Preterm Birth? A Nested Case-Control Study in China.

Liu, X.-T., Chen, D., Wang, B., Xu, F., Pang, Y., Zhang, L., Zhang, Y.-L., Jin, L., Li, Z.-W., & Ren, A. (2020) · Environmental Science and Technology · doi:10.1021/acs.est.0c01930 · Cited by 70 · see citing works

Per‐ and polyfluoroalkyl substances activate UPR pathway, induce steatosis and fibrosis in liver cells

Qi, Q., Niture, S. K., Gadi, S. V., Arthur, E., Moore, J. T., Levine, K. E., & Kumar, D. (2022) · Environmental Toxicology · doi:10.1002/tox.23680 · Cited by 77 · see citing works

Association between maternal exposure to perfluoroalkyl and polyfluoroalkyl substances and risks of adverse pregnancy outcomes: A systematic review and meta-analysis

Deji, Z., Liu, P., Wang, X., Zhang, X., Luo, Y., & Huang, Z. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.146984 · Cited by 64 · see citing works

Toxicity of perfluorooctanoic acid on zebrafish early embryonic development determined by single-cell RNA sequencing

Yu, J. H., Cheng, W., Jia, M., Chen, L., Gu, C., Ren, H., & Wu, B. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127888 · Cited by 62 · see citing works

Mechanism of immunosuppression in zebrafish (Danio rerio) spleen induced by environmentally relevant concentrations of perfluorooctanoic acid

Zhong, Y., Shen, L., Ye, X., Zhou, D., He, Y., & Zhang, H. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126200 · Cited by 59 · see citing works

Gestational bisphenol A exposure induces fatty liver development in male offspring mice through the inhibition of HNF1b and upregulation of PPARγ

Long, Z., Fan, J., Wu, G., Liu, X., Wu, H., Liu, J., Chen, Y., Su, S., Cheng, X., Xu, Z., et al. (2020) · Cell Biology and Toxicology · doi:10.1007/s10565-020-09535-3 · Cited by 58 · see citing works

Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA)

Souders, C. L., Sanchez, C. L., Malphurs, W. L., Aristizabal‐Henao, J. J., Bowden, J. A., & Martyniuk, C. J. (2021) · NeuroToxicology · doi:10.1016/j.neuro.2021.05.009 · Cited by 56 · see citing works

Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA

Xu, L., Chen, Y.-K., Zhang, Q.-Y., Chen, L., Zhang, K.-K., Li, J.-H., Liu, J.-L., Wang, Q., & Xie, X. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.153281 · Cited by 54 · see citing works

The relationship between perfluoroalkyl substances and hypertension: A systematic review and meta-analysis

Pan, K., Yu, J., Long, X., Yang, L., Huang, Z., & Yu, J. (2023) · Environmental Research · doi:10.1016/j.envres.2023.116362 · Cited by 54 · see citing works

Exposure to per- and polyfluoroalkyl substance and metabolic syndrome: A nationally representative cross-sectional study from NHANES, 2003-2018.

Wu, M., Zhu, Z., Wan, R., & Xu, J. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123615 · Cited by 49 · see citing works

Reduced Birth Weight and Exposure to Per- and Polyfluoroalkyl Substances: A Review of Possible Underlying Mechanisms Using the AOP-HelpFinder

Gundacker, C., Audouze, K., Widhalm, R., Granitzer, S., Forsthuber, M., Jornod, F., Wielsøe, M., Long, M., Halldorsson, T. I., Uhl, M., et al. (2022) · Toxics · doi:10.3390/toxics10110684 · Cited by 48 · see citing works

Influence of maternal endocrine disrupting chemicals exposure on adverse pregnancy outcomes: A systematic review and meta-analysis

Liu, B., Lü, X., Jiang, A., Lv, Y., Zhang, H., & Xu, B. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.115851 · Cited by 44 · see citing works

Mechanism of Placenta Damage in Gestational Diabetes Mellitus by Investigating TXNIP of Patient Samples and Gene Functional Research in Cell Line

Sarina, S., Li, D. F., Feng, Z. Q., Du, J., Zhao, W. H., Huang, N., Jia, J. C., Wu, Z. Y., Alamusi, Wang, Y. Y., et al. (2019) · Diabetes Therapy · doi:10.1007/s13300-019-00713-z · Cited by 43 · see citing works

Pre-differentiation exposure of PFOA induced persistent changes in DNA methylation and mitochondrial morphology in human dopaminergic-like neurons

Zhao, H., Xie, J., Wu, S., Sánchez, O. F., Zhang, X., Freeman, J. L., & Yuan, C. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.119684 · Cited by 34 · see citing works

Perfluorooctanoic acid (PFOA) induces cardiotoxicity by activating the Keap1/Nrf2 pathway in zebrafish (Danio rerio) embryos

Liu, X., Chen, R., Peng, Y., Zhou, Y., Xia, M., Wu, X., Wang, Y., Yin, W., Han, Y., & Yu, M. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117098 · Cited by 32 · see citing works

Integrated evidence of transcriptional, metabolic, and intestinal microbiota changes in Ruditapes philippinarum due to perfluorooctanoic acid-induced immunotoxicity

Li, F., Gong, X., Zhou, Y., Geng, Q., Jiang, Y., Lin, Y., Qu, M., & Tan, Z. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170341 · Cited by 28 · see citing works

Perfluorooctanoic acid exposure in vivo perturbs mitochondrial metabolic during oocyte maturation

Zhang, P., Qi, C., Ma, Z., Wang, Y., Zhang, L., & Hou, X. (2022) · Environmental Toxicology · doi:10.1002/tox.23652 · Cited by 29 · see citing works

Developmental toxicant exposures and sex-specific effects on epigenetic programming and cardiovascular health across generations

Svoboda, L. K., Ishikawa, T., & Dolinoy, D. C. (2022) · Environmental Epigenetics · doi:10.1093/eep/dvac017 · Cited by 27 · see citing works

Toxicity assessment of hexafluoropropylene oxide-dimer acid on morphology, heart physiology, and gene expression during zebrafish (Danio rerio) development

Gong, S., McLamb, F., Shea, D., Vu, J. P., Vasquez, M. F., Feng, Z., Bozinovic, K., Hirata, K. K., Gersberg, R. M., & Bozinovic, G. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-24542-z · Cited by 23 · see citing works

13C isotope-based metabolic flux analysis revealing cellular landscape of glucose metabolism in human liver cells exposed to perfluorooctanoic acid

Zhang, R., Chen, B., Lin, L., Zhang, H., & Luan, T. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.145329 · Cited by 22 · see citing works

Do perfluoroalkyl substances aggravate the occurrence of obesity-associated glucolipid metabolic disease?

Liu, H., Hu, W., Li, X., Hu, F., Xi, Y., Su, Z., Huang, Y., Liu, B., & Zhang, C. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111724 · Cited by 20 · see citing works

Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study

Xu, Z., Du, B., Wang, H., Li, Z., Wu, Y., Wang, Q., Niu, Y., Zhang, Q., Sun, K., Wang, J., et al. (2023) · Environmental Health · doi:10.1186/s12940-023-01023-5 · Cited by 21 · see citing works

Impacts of PFOAC8, GenXC6, and their mixtures on zebrafish developmental toxicity and gene expression provide insight about tumor-related disease

Liu, H., Chen, Y., Hu, W., Luo, Y., Zhu, P., You, S., Li, Y., Jiang, Z., Xi, Y., Su, Z., et al. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.160085 · Cited by 19 · see citing works

Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice

Xia, Y., Hao, L., Li, Y., Li, Y.-F., Chen, J., Li, L., Han, X., Liu, Y., Wang, X., & Li, D. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114497 · Cited by 18 · see citing works

Stomatin-like protein 2 (SLP2) regulates the proliferation and invasion of trophoblast cells by modulating mitochondrial functions

Zhang, X., Li, B., Fu, L., Adu‐Gyamfi, E. A., Xu, B.-R., Liu, T., Chen, X., Lan, X., Wang, Y., Xu, H.-B., et al. (2020) · Placenta · doi:10.1016/j.placenta.2020.07.008 · Cited by 16 · see citing works

Maternal plasma perfluoroalkyl substances concentrations in early pregnancy and cardiovascular development in offspring: A prospective cohort study

Wang, J., Du, B., Wu, Y., Li, Z., Wang, H., Niu, Y., Ye, Y., Chen, Q., Wang, Q., Wu, Y., et al. (2023) · Environment International · doi:10.1016/j.envint.2023.107748 · Cited by 17 · see citing works

Perfluorooctanoic acid affects mouse brain and liver tissue through oxidative stress

Endirlik, B. Ü., Eken, A., Canpınar, H., Öztürk, F., & Gürbay, A. (2022) · Archives of Industrial Hygiene and Toxicology · doi:10.2478/aiht-2022-73-3629 · Cited by 15 · see citing works

Perfluorooctanoic acid-induced developmental cardiotoxicity in chicken embryo: Roles of miR-490-5p

Guo, Y., Yuan, J., Ni, H., Ji, J., Zhong, S., Zheng, Y., & Jiang, Q. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.120022 · Cited by 15 · see citing works

Curcumin-Loaded Chitosan Nanoparticle Preparation and Its Protective Effect on Celecoxib-induced Toxicity in Rat isolated Cardiomyocytes and Mitochondria

Ebrahimi, H. A., Esmaeli, S., Khezri, S., & Salimi, A. (2022) · Drug Research · doi:10.1055/a-1960-3092 · Cited by 13 · see citing works

Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function

Yu, J., Duan, Y., Lu, Q., Chen, M., Ning, F., Ye, Y., Lu, S., Ou, D., Sha, X., Gan, X., et al. (2024) · Placenta · doi:10.1016/j.placenta.2024.04.011 · Cited by 13 · see citing works

Exploring the neurodegenerative potential of per- and polyfluoroalkyl substances through an adverse outcome pathway network

Mousavi, S. E., Yu, Q., & Shin, H. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.178972 · Cited by 13 · see citing works

Assessment of perfluorooctanoic acid toxicity in pancreatic cells

Abudayyak, M., Öztaş, E., & Özhan, G. (2021) · Toxicology in Vitro · doi:10.1016/j.tiv.2021.105077 · Cited by 13 · see citing works

Chronic PFAS exposure induces chemotherapy resistance by promoting mitochondria-related alterations in ovarian cancer cells

Rickard, B. P., Sapienza‐Lundie, L. A., Overchuk, M., Tulino, J., Mori, M. P., McCord, J. P., Chappell, V. A., Bortner, C. D., Bae-Jump, V. L., Santos, J. H., et al. (2025) · Environmental Research · doi:10.1016/j.envres.2025.122211 · Cited by 12 · see citing works

Maternal exposure to E 551 during pregnancy leads to genome-wide DNA methylation changes and metabolic disorders in the livers of pregnant mice and their fetuses

Zhan, Y., Lou, H., Shou, R., Li, A., Shang, J., Jin, Y., Lü, L., Zhu, L., Lu, X., & Fan, X. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.133233 · Cited by 12 · see citing works

Per- and Polyfluoroalkyl Substances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers

Baldwin, W. S., Davis, T. T., & Eccles, J. A. (2023) · Biomarkers in disease · doi:10.1007/978-3-031-07392-2_67 · Cited by 11 · see citing works

Inulin alleviates intestinal changes caused by gestational PFOA and GenX exposure in the offspring of mice through reshaping maternal gut microbiota and vertically inhibiting the TLR4/NF-κB/NLRP3 inflammatory pathway in the pups

Chen, Y.-K., Lai, M.-Q., Zhang, Q.-Y., Zhong, M.-T., Zhang, J., Chen, Y.-Q., Guo, X., Wang, Q., & Xie, X. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.126749 · Cited by 10 · see citing works

Mitochondrial dysfunction in pregnancy loss: a review

Lu, L., Huang, X., Shi, Y., Jiang, Y., Han, Y., & Zhang, Y. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05171-1 · Cited by 9 · see citing works

Hexafluoropropylene oxide homologues, the novel alternatives to PFOA, induce mitochondrial dysfunction and cytotoxicity in Leydig cells through disrupting SIRT1/PGC-1α signaling pathway

Le, M.-L., Xue, J.-Y., Wu, L.-H., Zhao, X., Ding, J., Yuan, Y., Wan, Y.-Q., & Zhang, D. (2025) · Toxicology · doi:10.1016/j.tox.2025.154282 · Cited by 8 · see citing works

Perfluorooctanoic Acid-Disturbed Serum and Liver Lipidome in C57BL/6 Mice

Gao, B., Tu, P., Chi, L., Shen, W., & Gao, N. (2022) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.2c00239 · Cited by 8 · see citing works

Prenatal Per‐ and Polyfluoroalkyl Substance Exposures and Longitudinal Blood Pressure Measurements in Children Aged 3 to 18 Years: Findings From a Racially and Ethnically Diverse US Birth Cohort

Li, Z., Wang, G., Hong, X., Brady, T. M., Pearson, C., Buckley, J. P., Wang, X., & Zhang, M. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.039949 · Cited by 7 · see citing works

Identifying possible neurodevelopmental effects of per- and polyfluoroalkyl substances (PFAS) through an adverse outcome pathway (AOP) network for human developmental neurotoxicology

Mousavi, S. E., Zarean, M., Yu, Q., Abbasi, S., & Kwong, R. W. M. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.181170 · Cited by 7 · see citing works

Perfluorooctanoic acid exposure and its neurodegenerative consequences in C57BL6/J mice

Neisiani, A. K., Mousavi, M. K., Soltani, M., & Aliomrani, M. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02387-8 · Cited by 7 · see citing works

Publication Trends on Mitophagy in the World and China: A 16-Year Bibliometric Analysis

Chen, J., Li, X., Jia, Y., Xia, Z., & Ye, J. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.793772 · Cited by 5 · see citing works

Prenatal Per- and Polyfluoroalkyl Substances (PFAS) Exposures, Newborn Mitochondrial DNA Copy Number, and the Modifying Role of the Maternal Folate Level

Li, Z., Qu, X., Hong, X., Wang, G., Song, M., Choi, G., Buckley, J. P., & Wang, X. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.5c06494 · Cited by 4 · see citing works

Human cerebral organoids reveal PFOA-induced axonal injury as a conserved mechanism of neurodevelopmental disruption

Chen, W.-R., Huang, Y., Zhou, W., Yang, J., Ren, T., Zhang, L., Zhu, T., Shan, X., Du, Y., Zhou, G., et al. (2026) · Environment International · doi:10.1016/j.envint.2026.110233 · Cited by 3 · see citing works

PFOA exposure causes variations of Acot1 among tissues in rats, and Acot1 in serum can be potentially used as a sensitive marker for health monitoring

Zhou, Y., Qiao, Y., Zhang, X., Ma, X., Liu, H., & Wang, L. (2022) · Toxicology Research · doi:10.1093/toxres/tfac065 · Cited by 4 · see citing works

Insights into the synergistic effects between deposited Fe oxides and dissolved organic matter in influencing perfluorooctanoic acid transport in saturated porous media

Xing, Y., Chen, X., Li, Q., Ji, L., Fu, X., & Wang, J. (2024) · Environmental Technology & Innovation · doi:10.1016/j.eti.2024.103838 · Cited by 4 · see citing works

Per- and Polyfluoroalkylsubstances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers

Baldwin, W. S., Davis, T. T., Eccles, J. A., & Absentia, I. (2022) · Biomarkers in disease · doi:10.1007/978-3-030-87225-0_67-1 · Cited by 3 · see citing works

Investigation of toxicity effect of TiCN coated on 304 SS and 410 SS substrates in rat fibroblasts and B-lymphocytes

Naserzadeh, P., Razmı, A., Yeşildal, R., & Ashtari, B. (2022) · Toxicology Research · doi:10.1093/toxres/tfac007 · Cited by 3 · see citing works

Assessing perfluorooctanoic acid toxicity in lung, heart, and testis tissues of mice: Evaluation of protective effects of taurine and coenzyme Q10

Endirlik, B. Ü., Eken, A., Öztürk, F., & Gürbay, A. (2023) · Journal of Research in Pharmacy · doi:10.29228/jrp.326 · Cited by 2 · see citing works

Insights into the Neurotoxicology of Traditional and Emerging Per- and Polyfluoroalkyl Substances: Mechanisms and Research Frontiers

Ren, Z., Wang, X., Meng, L., Ren, D., Sun, J., Cai, Y., Duan, Y., Ning, X., Ku, T., & Sang, N. (2026) · Environment & Health · doi:10.1021/envhealth.5c00628 · Cited by 2 · see citing works

Mephedrone as a new synthetic amphetamine induces abortion, morphological alterations and mitochondrial dysfunction in mouse embryos

Salimi, A., Kazemnezhad, M., Asl, B. M., Jokar, F., Jamali, Z., & Pourahmad, J. (2020) · Toxin Reviews · doi:10.1080/15569543.2020.1803358 · Cited by 2 · see citing works

Elucidating the potential neurotoxicity of chiral phenthoate: Molecular insight from experimental and computational studies

Ding, F., Peng, W., Peng, Y.-K., & Liu, B.-Q. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.127007 · Cited by 2 · see citing works

Integrating population epidemiology and bioinformatics to decipher the hypertensive effects of per- and polyfluoroalkyl substances mixtures

Lai, J.-F., Tu, H.-X., Zhang, Y.-Q., Amjad, M., Yang, Q., He, Y., Zhang, Y.-T., Liang, L.-X., Dong, G., & Liu, R.-Q. (2026) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2026.101148 · Cited by 1 · see citing works

Toxicity of superparamagnetic iron oxide nanoparticles on retinoblastoma mitochondria

Seydi, E., Tahmasebi, G., Arjmand, A., & Pourahmad, J. (2023) · Cutaneous and Ocular Toxicology · doi:10.1080/15569527.2023.2275030 · Cited by 1 · see citing works

Long/Short-Chain Pfass and Their Mixtures on Zebrafish Embryos Developmental Toxicity and Relevant Gene Regulation Mechanisms: Enlightenment to Human HealthPreprint

Liu, H., Chen, Y., Hu, W., Luo, Y., Zhu, P. S., You, S., Li, Y., Jiang, Z., Xi, Y., Su, Z. M., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4002343

Maternal Exposure to Perfluoroalkyl Substances in Early Pregnancy and Cardiovascular Development in OffspringPreprint

Wang, J., Du, B., Wu, Y., Li, Z., Wang, H., Niu, Y., Ye, Y., Chen, Q., Wang, Q., Wu, Y., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4145595

Maternal Exposure to Perfluoroalkyl Substances in Early Pregnancy and Cardiovascular Development in Offspring: A Prospective Cohort StudyPreprint

Wang, J., Du, B., Wu, Y., Li, Z., Wang, H., Niu, Y., Ye, Y., Chen, Q., Wang, Q., Wu, Y., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4170055

Per- and Polyfluoroalkylsubstances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers

Baldwin, W. S., Davis, T. T., & Eccles, J. A. (2023) · Biomarkers in disease · doi:10.1007/978-3-030-87225-0_67-2

Could the Risk of Chronic Degenerative Valve Disease (CDVD) in Dogs Depend on Exposure to Endocrine-Disrupting Chemicals Polluting the Environment?

Makowska, K., Martı́n, J., Pasławski, R., Rychlik, A., Aparicio, I., Santos, J. L., Alonso, E., Górecka-Politańska, M., & Gonkowski, S. (2025) · Animals · doi:10.3390/ani15233443

Additional file 1 of Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study

Xu, Z., Du, B., Wang, H., Li, Z., Wu, Y., Wang, Q., Niu, Y., Zhang, Q., Sun, K., Wang, J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24406730

Advances in the Distribution, Transport, and Transformation of PFAS in the Drinking Water System: From Source to Tap

Yang, H.-W., He, W.-Y., Li, D.-W., Pan, X., Li, X., Zhu, Q., Xiang, H., & Ouyang, E.-M. (2026) · Water environment research · doi:10.1002/wer.70299

Co-exposure of polyethylene terephthalate micro- and nanoplastics with per- and polyfluoroalkyl substances triggers immune dysregulation, apoptotic activation, and neurotoxicity

Dharshan, S. S., Madesh, S., Rao, S. M., Ramamurthy, K., Rajagopal, R., Alfarhan, A. H., Choi, K. C., & Arockiaraj, J. (2026) · Ecotoxicology · doi:10.1007/s10646-025-03017-0

Perfluorooctanoic acid (PFOA) induces lipid accumulation, oxidative stress, and reduced neurogenesis in primary human neuronal progenitor cells

Marinello, W. P., & Zylka, M. J. (2026) · Frontiers in Toxicology · doi:10.3389/ftox.2026.1814052

Assessment of acute functional effects of perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and hexafluoropropylene oxide dimer acid (HFPO-DA) in human iPSC-derived cardiomyocytes using multielectrode arrays

Kim, M. W., Lee, M., Park, J. H., Lee, S.-G., Oh, J.-S., Park, S., Jeong, Y., Kim, Y., Shin, H., Kim, C., et al. (2026) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2026.105184

Perfluorooctanoic acid (PFOA) exposure affects early embryonic development and offspring oocyte quality via inducing mitochondrial dysfunction

Zhou, Y., Li, R., Li, S., Ma, X., Liu, L., Niu, D., & Duan, X. (2022) · Environment International · doi:10.1016/j.envint.2022.107413 · Cited by 114 · see citing works

Hepatic Mitochondrial Alteration in CD-1 Mice Associated with Prenatal Exposures to Low Doses of Perfluorooctanoic Acid (PFOA)

Quist, E. M., Filgo, A. J., Cummings, C. A., Kissling, G. E., Hoenerhoff, M. J., & Fenton, S. E. (2014) · Toxicologic Pathology · doi:10.1177/0192623314551841 · Cited by 67 · see citing works

Mechanistic approach for the toxic effects of perfluorooctanoic acid on isolated rat liver and brain mitochondria

Mashayekhi, V., Tehrani, K. H. M. E., Hashemzaei, M., Tabrizian, K., Shahraki, J., & Hosseini, M.-J. (2015) · Human & Experimental Toxicology · doi:10.1177/0960327114565492 · Cited by 70 · see citing works

Effects of perfluorooctanoic acid exposure during pregnancy in the mouse.

Lau, C., Thibodeaux, J. R., Hanson, R., Narotsky, M., Rogers, J. M., Lindstrom, A., & Strynar, M. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj105 · Cited by 547 · see citing works

Perfluorooctanoic acid exposure in early pregnancy induces oxidative stress in mice uterus and liver

Zhang, Y., Zhang, L., Bao, J., Liu, L., & Wang, X. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-15453-6 · Cited by 16 · see citing works