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Reference ranges for uterine artery mean pulsatility index at 11–41 weeks of gestation

Gómez, O., Figueras, F., Fernández, S., Bennasar, M., Martínez, J. M., Puerto, B., Gratacós, E.·2008·Ultrasound in Obstetrics & Gynecology

Abstract

Objectives: To construct gestational age (GA)‐based reference ranges for the uterine artery (UtA) mean pulsatility index (PI) at 11–41 weeks of pregnancy. Methods: A prospective cross‐sectional observational study was carried out of 20 consecutive singleton pregnancies for each completed gestational week at 11–41 weeks. UtAs were examined by color and pulsed Doppler imaging, and the mean PI, as well as the presence or absence of a bilateral protodiastolic notch, were recorded. Polynomials were fitted by means of least‐square regression to estimate the relationship between the mean UtA‐PI and GA. Results: A total of 620 women were included. A second‐degree polynomial (Log e mean UtA‐PI = 1.39 − 0.012 × GA + GA 2 × 0.0000198, with GA measured in days), after a natural logarithmic transformation, was selected to model our data. There was a significant decrease in the mean UtA‐PI between 11 weeks (mean PI, 1.79; 95th centile, 2.70) and 34 weeks (mean PI, 0.70; 95th centile, 0.99). It then became more stable up until 41 weeks (mean PI, 0.65; 95th centile, 0.89). Conclusions: The mean UtA‐PI shows a progressive decrease until the late stages of pregnancy. Reference ranges for mean UtA‐PI may have clinical value in screening for placenta‐associated diseases in the early stages of pregnancy, and in evaluating patients with pregnancy‐induced hypertension and/or small‐for‐gestational age fetuses during the third trimester. Copyright © 2008 ISUOG. Published by John Wiley & Sons, Ltd.

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Metadata

Authors
Gómez, O., Figueras, F., Fernández, S., Bennasar, M., Martínez, J. M., Puerto, B., & Gratacós, E.
Venue
Ultrasound in Obstetrics & Gynecology
Publisher
Wiley
Published
2008-05-06
Volume
32
Issue
2
Pages
128-132
ISSN
  • 0960-7692 (ISSN-L)
  • 1469-0705
OpenAlex
W2019033274
Cited by
592
References
29
FWCI
13.22
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Reference ranges for uterine artery mean pulsatility index at 11–41 weeks of gestation. https://app.cochat.ai/papers/10.1002/uog.5315
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Gómez, O., Figueras, F., Fernández, S., Bennasar, M., Martínez, J. M., Puerto, B., & Gratacós, E. (2008). Reference ranges for uterine artery mean pulsatility index at 11–41 weeks of gestation. Ultrasound in Obstetrics & Gynecology. https://doi.org/10.1002/uog.5315

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