Identification of a Natural Soluble Form of the Vascular Endothelial Growth Factor Receptor, FLT-1, and Its Heterodimerization with KDR

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Maynard, S. E., Min, J.-Y., Merchan, J., Lim, K.-H., Li, J., Mondal, S., Libermann, T. A., Morgan, J. P., Sellke, F. W., Stillman, I. E., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17189 · Cited by 4,101

The splice variants of vascular endothelial growth factor (VEGF) and their receptors

Robinson, C. J., & Stringer, S. E. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.5.853 · Cited by 944

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

Chaiworapongsa, T., Romero, R., Kim, Y. M., Kim, G. J., Kim, M. R., Espinoza, J., Bujold, E., Gonçalves, L., Gomez, R., Edwin, S., et al. (2005) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050400028816 · Cited by 359

Receptor Tyrosine Kinase-Targeted Cancer Therapy

Yamaoka, T., Kusumoto, S., Ando, K., Ohba, M., & Ohmori, T. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113491 · Cited by 297

Vascular endothelial growth factor and endometriotic angiogenesis

McLaren, J. (2000) · Human Reproduction Update · doi:10.1093/humupd/6.1.45 · Cited by 269

Endogenous inhibitors of angiogenesis

Ribatti, D. (2009) · Leukemia Research · doi:10.1016/j.leukres.2008.11.019 · Cited by 191

Vascular Endothelial Growth Factor Is Necessary in the Development of Arteriosclerosis by Recruiting/Activating Monocytes in a Rat Model of Long-Term Inhibition of Nitric Oxide Synthesis

Zhao, Q., Egashira, K., Inoue, S., Usui, M., Kitamoto, S., Ni, W., Ishibashi, M., Hiasa, K.-I., Ichiki, T., Shibuya, M., et al. (2002) · Circulation · doi:10.1161/hc0902.104718 · Cited by 136

Hypoxia: Adapting to High Altitude by Mutating EPAS-1 , the Gene Encoding HIF-2α

Tissot van Patot, M. C., & Gassmann, M. (2011) · High Altitude Medicine & Biology · doi:10.1089/ham.2010.1099 · Cited by 119

VEGF is required for dendritogenesis of newly born olfactory bulb interneurons

Licht, T., Eavri, R., Goshen, I., Shlomai, Y., Mizrahi, A., & Keshet, E. (2010) · Development · doi:10.1242/dev.039636 · Cited by 86

Hypoxia-inducible factor-2α regulates GM-CSF–derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis

Roda, J. M., Sumner, L. A., Evans, R., Phillips, G. S., Marsh, C. B., & Eubank, T. D. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100841 · Cited by 74

Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update

Lin, F.-L., Wang, P.-Y., Chuang, Y.-F., Wang, J.-H., Wong, V. H. Y., Bui, B. V., & Liu, G.-S. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.06.029 · Cited by 74

Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model

Roda, J. M., Wang, Y., Sumner, L. A., Phillips, G. S., Marsh, C. B., & Eubank, T. D. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103817 · Cited by 71

Evaluation of Serum and Urinary Angiogenic Factors in Patients with Endometriosis

Cho, S. H., Oh, Y. J., Nam, A., Kim, H. Y., Park, J. H., Kim, J. H., Park, K. H., Cho, D. J., & Lee, B. S. (2007) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2007.00535.x · Cited by 68

Brain homeostasis: VEGF receptor 1 and 2—two unequal brothers in mind

Wittko-Schneider, I. M., Schneider, F. T., & Plate, K. H. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1279-3 · Cited by 62

Helper-Dependent Adenovirus for the Gene Therapy of Proliferative Retinopathies: Stable Gene Transfer, Regulated Gene Expression and Therapeutic Efficacy

Lamartina, S., Cimino, M., Roscilli, G., Dammassa, E., Lazzaro, D., Rota, R., Ciliberto, G., & Toniatti, C. (2007) · The Journal of Gene Medicine · doi:10.1002/jgm.1083 · Cited by 59

Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice

Szalai, G., Romero, R., Chaiworapongsa, T., Xu, Y., Wang, B., Ahn, H., Xu, Z., Chiang, P. J., Sundell, B., Wang, R., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119547 · Cited by 46

Role of extracellular signal-regulated kinase and AKT cascades in regulating hypoxia-induced angiogenic factors produced by a trophoblast-derived cell line

Fujita, D., Tanabe, A., Sekijima, T., Soen, H., Narahara, K., Yamashita, Y., Terai, Y., Kamegai, H., & Ohmichi, M. (2010) · Journal of Endocrinology · doi:10.1677/joe-10-0027 · Cited by 33

Mechanistic computational modeling of sFLT1 secretion dynamics

Gill, A., Kinghorn, K., Bautch, V. L., & Mac Gabhann, F. (2025) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1013324 · Cited by 1