The role of microRNAs in human diseases

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M. J., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 4,992 · see citing works

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., Guo, J., Zhang, Y., Chen, J., Guo, X., et al. (2008) · Cell Research · doi:10.1038/cr.2008.282 · Cited by 4,560 · see citing works

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., Mitchell, P. S., Bennett, C. F., Pogosova-Agadjanyan, E. L., Stirewalt, D. L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019055108 · Cited by 3,294 · see citing works

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Vickers, K. C., Palmisano, B. T., Shoucri, B. M., Shamburek, R. D., & Remaley, A. T. (2011) · Nature Cell Biology · doi:10.1038/ncb2210 · Cited by 2,741 · see citing works

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

Ma, L., Teruya-Feldstein, J., & Weinberg, R. A. (2007) · Nature · doi:10.1038/nature06174 · Cited by 2,605 · see citing works

A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

Calin, G. A., Ferracin, M., Cimmino, A., Leva, G. D., Shimizu, M., Wojcik, S. E., Iorio, M. V., Visone, R., Sever, N. İ., Fabbri, M., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050995 · Cited by 2,403 · see citing works

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

Kosaka, N., Iguchi, H., Yoshioka, Y., Takeshita, F., Matsuki, Y., & Ochiya, T. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.107821 · Cited by 1,950 · see citing works

Endogenous human microRNAs that suppress breast cancer metastasis

Tavazoie, S. F., Alarcón, C. R., Óskarsson, T., Padua, D. M., Wang, Q., Bos, P. D., Gerald, W. L., & Massagué, J. (2008) · Nature · doi:10.1038/nature06487 · Cited by 1,858 · see citing works

Detection of elevated levels of tumour‐associated microRNAs in serum of patients with diffuse large B‐cell lymphoma

Lawrie, C. H., Gal, S., Dunlop, H. M., Pushkaran, B., Liggins, A. P., Pulford, K. A. F., Banham, A. H., Pezzella, F., Boultwood, J., Wainscoat, J. S., et al. (2008) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07077.x · Cited by 1,739 · see citing works

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

van Rooij, E., Sutherland, L. B., Liu, N., Williams, A. H., McAnally, J., Gerard, R. D., Richardson, J. A., & Olson, E. N. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608791103 · Cited by 1,507 · see citing works

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

Hunter, M. P., Ismail, N., Zhang, X., Aguda, B. D., Lee, E. J., Yu, L., Xiao, T., Schafer, J., Lee, M. T., Schmittgen, T. D., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003694 · Cited by 1,453 · see citing works

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

Zernecke, A., Bidzhekov, K., Noels, H., Shagdarsuren, E., Gan, L., Denecke, B., Hristov, M., Koeppel, T. A., Nazari-Jahantigh, M., Lutgens, E., et al. (2009) · Science Signaling · doi:10.1126/scisignal.2000610 · Cited by 1,335 · see citing works

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

Rabinowits, G., Gerçel-Taylor, Ç., Day, J. M., Taylor, D. D., & Kloecker, G. H. (2009) · Clinical Lung Cancer · doi:10.3816/clc.2009.n.006 · Cited by 1,261 · see citing works

Genetic variation in microRNA networks: the implications for cancer research

Ryan, B. M., Robles, A. I., & Harris, C. C. (2010) · Nature reviews. Cancer · doi:10.1038/nrc2867 · Cited by 1,260 · see citing works

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

Clop, A., Marcq, F., Takeda, H., Pirottin, D., Tordoir, X., Bibé, B., Bouix, J., Caiment, F., Elsen, J.-M., Eychenne, F., et al. (2006) · Nature Genetics · doi:10.1038/ng1810 · Cited by 1,260 · see citing works

Circulating MicroRNAs in Patients With Coronary Artery Disease

Fichtlscherer, S., Rosa, S. D., Fox, H., Schwietz, T., Fischer, A., Liebetrau, C., Weber, M. A., Hamm, C. W., Roexe, T., Müller-Ardogan, M., et al. (2010) · Circulation Research · doi:10.1161/circresaha.109.215566 · Cited by 1,222 · see citing works

A microRNA DNA methylation signature for human cancer metastasis

Lujambio, A., Calin, G. A., Villanueva, A., Ropero, S., Sánchez‐Céspedes, M., Blanco, D., Montuenga, L. M., Rossi, S., Nicoloso, M. S., Faller, W. J., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803055105 · Cited by 1,078 · see citing works

Sequence Variants in <i>SLITRK1</i> Are Associated with Tourette's Syndrome

Abelson, J. F., Kwan, K. Y., O'Roak, B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rašin, M.-R., Gunel, M., et al. (2005) · Science · doi:10.1126/science.1116502 · Cited by 940 · see citing works

Common SNP in <i>pre-miR-146a</i> decreases mature miR expression and predisposes to papillary thyroid carcinoma

Jazdzewski, K., Murray, E. L., Franssila, K., Jarzab, B., Schoenberg, D. R., & de la Chapelle, A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802682105 · Cited by 842 · see citing works

Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer

Hu, Z., Chen, X., Zhao, Y., Tian, T., Jin, G., Shu, Y., Chen, Y., Xu, L., Zen, K., Zhang, C., et al. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.24.9342 · Cited by 796 · see citing works

Circulating microRNAs as Novel Minimally Invasive Biomarkers for Breast Cancer

Heneghan, H., Miller, N., Lowery, A., Sweeney, K., Newell, J., & Kerin, M. J. (2010) · Annals of Surgery · doi:10.1097/sla.0b013e3181cc939f · Cited by 681 · see citing works

Extracellular microRNA: A new source of biomarkers

Etheridge, A., Lee, I., Hood, L., Galas, D. J., & Wang, K. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.03.004 · Cited by 662 · see citing works

The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform

Resnick, K. E., Alder, H., Hagan, J. P., Richardson, D. L., Croce, C. M., & Cohn, D. E. (2008) · Gynecologic Oncology · doi:10.1016/j.ygyno.2008.08.036 · Cited by 647 · see citing works

A SNP in a let-7 microRNA Complementary Site in the KRAS 3′ Untranslated Region Increases Non–Small Cell Lung Cancer Risk

Chin, L. J., Ratner, E., Leng, S., Zhai, R., Nallur, S. V., Babar, I., Müller, R., Straka, E., Su, L., Burki, E. A., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-2129 · Cited by 634 · see citing works

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

Jeyaseelan, K., Lim, K. Y., & Armugam, A. (2008) · Stroke · doi:10.1161/strokeaha.107.500736 · Cited by 587 · see citing works

MicroRNAs and epigenetics

Sato, F., Tsuchiya, S., Meltzer, S. J., & Shimizu, K. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08089.x · Cited by 586 · see citing works

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

Mencía, Á., Modamio-Høybjør, S., Redshaw, N., Morín, M., Mayo-Merino, F., Olavarrieta, L., Aguirre, L. A., del Castillo, I., Steel, K. P., Dalmay, T., et al. (2009) · Nature Genetics · doi:10.1038/ng.355 · Cited by 550 · see citing works

A Comprehensive Analysis of Common Copy-Number Variations in the Human Genome

Wong, K. K. Y., deLeeuw, R. J., Dosanjh, N. S., Kimm, L. R., Cheng, Z., Horsman, D. E., MacAulay, C. E., Ng, R. T., Brown, C. J., Eichler, E. E., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/510560 · Cited by 518 · see citing works

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

Hullinger, T. G., Montgomery, R. L., Seto, A. G., Dickinson, B., Semus, H. M., Lynch, J. M., Dalby, C. M., Robinson, K., Stack, C., Latimer, P. A., et al. (2011) · Circulation Research · doi:10.1161/circresaha.111.244442 · Cited by 502 · see citing works

Brain and Blood microRNA Expression Profiling of Ischemic Stroke, Intracerebral Hemorrhage, and Kainate Seizures

Liu, D.-Z., Tian, Y., Ander, B. P., Xu, H., Stamova, B. S., Zhan, X., Turner, R. J., Jickling, G. C., & Sharp, F. R. (2009) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2009.186 · Cited by 496 · see citing works

Circulating microRNAs: Association with disease and potential use as biomarkers

Reid, G., Kirschner, M. B., & van Zandwijk, N. (2010) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2010.11.004 · Cited by 465 · see citing works

Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer

Asaga, S., Kuo, C. T., Nguyen, T. T., Terpenning, M., Giuliano, A. E., & Hoon, D. S. �. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2010.151845 · Cited by 451 · see citing works

The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function

Brueckner, B., Stresemann, C., Kuner, R., Mund, C., Musch, T., Meister, M. A., Sültmann, H., & Lyko, F. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4074 · Cited by 444 · see citing works

Variation in the miRNA-433 Binding Site of FGF20 Confers Risk for Parkinson Disease by Overexpression of α-Synuclein

Wang, G., van der Walt, J. M., Mayhew, G. M., Li, Y., Zuchner, S. L., Scott, W. K., Martin, E. R., & Vance, J. M. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.021 · Cited by 441 · see citing works

Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer

Roth, C., Rack, B. K., Müller, V., Janni, W., Pantel, K., & Schwarzenbach, H. (2010) · Breast Cancer Research · doi:10.1186/bcr2766 · Cited by 431 · see citing works

Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders.

Miller, D. T., Shen, Y., Weiss, L. A., Korn, J., Anselm, I., Bridgemohan, C., Cox, G. F., Dickinson, H., Gentile, J., Harris, D. J., et al. (2009) · Journal of Medical Genetics · doi:10.1136/jmg.2008.059907 · Cited by 427 · see citing works

A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance

Mishra, P. J., Humeniuk, R., Mishra, P. J., Longo-Sorbello, G. S. A., Banerjee, D., & Bertino, J. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706217104 · Cited by 417 · see citing works

Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles

Yuan, A., Farber, E. L., Rapoport, A. L., Tejada, D., Deniskin, R., Akhmedov, N. B., & Farber, D. B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004722 · Cited by 416 · see citing works

Altered expression of microRNA‐203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

Stańczyk, J., Ospelt, C., Karouzakis, E., Filer, A. D., Raza, K., Kolling, C., Gay, R., Buckley, C. D., Tak, P. P., Gay, S., et al. (2010) · Arthritis & Rheumatism · doi:10.1002/art.30115 · Cited by 407 · see citing works

Diagnostic Assay Based on hsa-miR-205 Expression Distinguishes Squamous From Nonsquamous Non–Small-Cell Lung Carcinoma

Lebanony, D., Benjamin, H., Gilad, S., Ezagouri, M., Dov, A., Ashkenazi, K., Gefen, N., Izraeli, S., Rechavi, G., Pass, H. I., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.19.4134 · Cited by 407 · see citing works

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

Gong, J., Tong, Y., Zhang, H., Wang, K., Hu, T., Shan, G., Sun, J., & Guo, A. (2011) · Human Mutation · doi:10.1002/humu.21641 · Cited by 375 · see citing works

MicroRNAs in Human Diseases: From Cancer to Cardiovascular Disease

Ha, T.-Y. (2011) · Immune Network · doi:10.4110/in.2011.11.3.135 · Cited by 367 · see citing works

miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer

Augoff, K., McCue, B., Plow, E. F., & Sossey‐Alaoui, K. (2012) · Molecular Cancer · doi:10.1186/1476-4598-11-5 · Cited by 362 · see citing works

Circulating microRNAs in breast cancer and healthy subjects

Zhu, W., Qin, W., Atasoy, U., & Sauter, E. R. (2009) · BMC Research Notes · doi:10.1186/1756-0500-2-89 · Cited by 359 · see citing works

A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

Melo, S. A., Moutinho, C., Ropero, S., Calin, G. A., Rossi, S., Spizzo, R., Fernández, A. F., Dávalos, V., Villanueva, A., Montoya, G., et al. (2010) · Cancer Cell · doi:10.1016/j.ccr.2010.09.007 · Cited by 347 · see citing works

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis

Shen, J., Ambrosone, C. B., DiCioccio, R. A., Odunsi, K. O., Lele, S., & Zhao, H. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn172 · Cited by 347 · see citing works

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development · doi:10.1242/dev.025080 · Cited by 343 · see citing works

Systemic miRNA-195 Differentiates Breast Cancer from Other Malignancies and Is a Potential Biomarker for Detecting Noninvasive and Early Stage Disease

Heneghan, H., Miller, N., Kelly, R., Newell, J., & Kerin, M. J. (2010) · The Oncologist · doi:10.1634/theoncologist.2010-0103 · Cited by 317 · see citing works

Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans

de Pontual, L., Yao, E. S., Callier, P., Faivre, L. O., Drouin‐Garraud, V., Cariou, S., van Haeringen, A., Geneviève, D., Goldenberg, A., Oufadem, M., et al. (2011) · Nature Genetics · doi:10.1038/ng.915 · Cited by 295 · see citing works

Hypermethylation of let-7a-3 in Epithelial Ovarian Cancer Is Associated with Low Insulin-like Growth Factor-II Expression and Favorable Prognosis

Lu, L., Katsaros, D., de la Longrais, I. A. R., Sochirca, O., & Yu, H. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-2544 · Cited by 282 · see citing works

Evaluation of Genetic Variants in MicroRNA-Related Genes and Risk of Bladder Cancer

Yang, H., Dinney, C. P., Ye, Y., Zhu, Y., Grossman, H. B., & Wu, X. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-5991 · Cited by 266 · see citing works

A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

Luo, X., Yang, W., Ye, D., Cui, H., Zhang, Y., Hirankarn, N., Qian, X., Tang, Y., Lau, Y., de Vries, N., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002128 · Cited by 262 · see citing works

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion

Mukai, J., Dhilla, A., Drew, L. J., Stark, K. L., Cao, L., MacDermott, A. B., Karayiorgou, M., & Gogos, J. A. (2008) · Nature Neuroscience · doi:10.1038/nn.2204 · Cited by 260 · see citing works

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

Bousquet, M., Quelen, C., Rosati, R., Mas, V. M., Starza, R. L., Bastard, C., Lippert, É., Talmant, P., Lafage‐Pochitaloff, M., Leroux, D., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20080285 · Cited by 248 · see citing works

miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo

Ouyang, Y., Lu, Y., Yue, S., et al. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.09.012 · Cited by 239 · see citing works

Single Nucleotide Polymorphisms of microRNA Machinery Genes Modify the Risk of Renal Cell Carcinoma

Horikawa, Y., Wood, C. G., Yang, H., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-1199 · Cited by 233 · see citing works

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

Wang, P., Chen, L., Zhang, J., Chen, H., Fan, J., Wang, K., Luo, J., Chen, Z., Meng, Z., & Liu, L. (2013) · Oncogene · doi:10.1038/onc.2012.598 · Cited by 224 · see citing works

Genetic Variations in MicroRNA-Related Genes Are Novel Susceptibility Loci for Esophageal Cancer Risk

Ye, Y., Wang, K. K., Gu, J. H., Yang, H., Lin, J. M., Ajani, J. A., & Wu, X. (2008) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-08-0135 · Cited by 222 · see citing works

MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia

Yang, G.-Y. (2011) · Frontiers in Bioscience-Elite · doi:10.2741/e330 · Cited by 190 · see citing works

A functional polymorphism in Pre‐miR‐146a gene is associated with prostate cancer risk and mature miR‐146a expression in vivo

Xu, B., Feng, N., Li, P., Tao, J., Wu, D., Zhang, Z., Tong, N., Wang, J., Song, N., Zhang, W., et al. (2009) · The Prostate · doi:10.1002/pros.21080 · Cited by 186 · see citing works

MicroRNA profiling in cancer

Munker, R., & Calin, G. A. (2011) · Clinical Science · doi:10.1042/cs20110005 · Cited by 174 · see citing works

Association of MicroRNA-196a-2 Gene Polymorphism with Gastric Cancer Risk in a Chinese Population

Peng, S., Kuang, Z., Sheng, C., et al. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-1007-x · Cited by 172 · see citing works

MicroRNA expression profiling in classic Hodgkin lymphoma

Navarro, A., Gayà, A., Martı́nez, A., Urbano-Ispizúa, Á., Pons, A., Balagué, O., Gel, B., Abrisqueta, P., López‐Guillermo, A., Artells, R., et al. (2007) · Blood · doi:10.1182/blood-2007-06-096784 · Cited by 170 · see citing works

The role of microRNA in rheumatoid arthritis and other autoimmune diseases

Furer, V., Greenberg, J. D., Attur, M. G., Abramson, S. B., & Pillinger, M. H. (2010) · Clinical Immunology · doi:10.1016/j.clim.2010.02.005 · Cited by 168 · see citing works

Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients

Eitan, R., Kushnir, M., Lithwick‐Yanai, G., David, M., Hoshen, M., Glezerman, M., Hod, M., Sabah, G., Rosenwald, S., & Levavi, H. (2009) · Gynecologic Oncology · doi:10.1016/j.ygyno.2009.04.024 · Cited by 161 · see citing works

Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker

Brendle, A., Lei, H., Brandt, A., et al. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn126 · Cited by 153 · see citing works

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity

Asuthkar, S., Velpula, K. K., Chetty, C., Gorantla, B., & Rao, J. S. (2012) · Oncotarget · doi:10.18632/oncotarget.683 · Cited by 150 · see citing works

MicroRNAs as biomarkers for CNS cancer and other disorders

Smaele, E. D., Ferretti, E., & Gulino, A. (2010) · Brain Research · doi:10.1016/j.brainres.2010.03.103 · Cited by 149 · see citing works

Serum and urinary free microRNA level in patients with systemic lupus erythematosus

Wang, G., Tam, L., Li, E., Kwan, B. C., Chow, K.-M., Luk, C. C., Li, P., & Szeto, C. (2011) · Lupus · doi:10.1177/0961203310389841 · Cited by 146 · see citing works

Epigenetic Regulation of MicroRNAs in Acute Lymphoblastic Leukemia

Román‐Gómez, J., Agirre, X., Jiménez‐Velasco, A., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.19.3441 · Cited by 140 · see citing works

Genetic Variants in MicroRNA Biosynthesis Pathways and Binding Sites Modify Ovarian Cancer Risk, Survival, and Treatment Response

Liang, D., Meyer, L. A., Chang, D. W., Lin, J. M., Pu, X., Ye, Y., Gu, J. H., Wu, X., & Lu, K. H. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0130 · Cited by 132 · see citing works

Innovative Electrochemical Approach for an Early Detection of microRNAs

Lusi, E. A., Passamano, M., Guarascio, P., et al. (2009) · Analytical Chemistry · doi:10.1021/ac8026788 · Cited by 130 · see citing works

miR-34b Targets Cyclic AMP–Responsive Element Binding Protein in Acute Myeloid Leukemia

Pigazzi, M., Manara, E., Baron, E., & Basso, G. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3404 · Cited by 128 · see citing works

Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha

Scotto, L., Narayan, G., Nandula, S. V., et al. (2008) · Molecular Cancer · doi:10.1186/1476-4598-7-58 · Cited by 123 · see citing works

MicroRNA expression changes in lymphoblastoid cell lines in response to lithium treatment

Chen, H., Wang, N., Burmeister, M., & McInnis, M. G. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709000029 · Cited by 121 · see citing works

Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia

Sonoki, T., Iwanaga, E., Mitsuya, H., et al. (2005) · Leukemia · doi:10.1038/sj.leu.2403938 · Cited by 115 · see citing works

miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells

Kuhn, S., Johnson, S. L., Furness, D. N., Chen, J., Ingham, N., Hilton, J. M., Steffes, G., Lewis, M. A., Zampini, V., Hackney, C. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016646108 · Cited by 114 · see citing works

Localization‐ and mutation‐dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co‐expressed miRNAs located at 14q32.31

Haller, F., von Heydebreck, A., Zhang, J. D., Gunawan, B., Langer, C., Ramadori, G. P., Wiemann, S., & Şahin, Ö. (2009) · The Journal of Pathology · doi:10.1002/path.2610 · Cited by 114 · see citing works

MicroRNA-218 Is Deleted and Downregulated in Lung Squamous Cell Carcinoma

Davidson, M. R., Larsen, J. E., Yang, I. A., Hayward, N. K., Clarke, B. E., Duhig, E., Passmore, L. H., Bowman, R., & Fong, K. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012560 · Cited by 114 · see citing works

MicroRNA‐137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck

Langevin, S. M., Stone, R. A., Bunker, C. H., Lyons‐Weiler, M. A., LaFramboise, W. A., Kelly, L. A., Seethala, R. R., Grandis, J. R., Sobol, R. W., & Taioli, E. (2010) · Cancer · doi:10.1002/cncr.25689 · Cited by 109 · see citing works

The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease

Tüfekçi, K. U., Genç, Ş., & Genç, K. (2011) · Parkinson s Disease · doi:10.4061/2011/487450 · Cited by 108 · see citing works

Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion

Li, Y., Kong, D., Ahmad, A., Bao, B., Dyson, G. E., & Sarkar, F. H. (2012) · Epigenetics · doi:10.4161/epi.21236 · Cited by 106 · see citing works

A functional varient in microRNA-146a is associated with risk of esophageal squamous cell carcinoma in Chinese Han

Guo, H., Wang, K., Xiong, G., Hu, H., Wang, D., Xu, X., Guan, X., Yang, K., & Bai, Y. (2010) · Familial Cancer · doi:10.1007/s10689-010-9370-5 · Cited by 105 · see citing works

MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer

Tang, J. T., Wang, J., Du, W., et al. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr114 · Cited by 105 · see citing works

Circulating miR-142-3p levels in patients with systemic sclerosis

Makino, K., Jinnin, M., Kajihara, I., Honda, N., Sakai, K., Masuguchi, S., Fukushima, S., Inoue, Y., & Ihn, H. (2011) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.2011.04158.x · Cited by 99 · see citing works

Genetic variation in MicroRNA genes and risk of oral premalignant lesions

Clague, J., Lippman, S. M., Yang, H., et al. (2009) · Molecular Carcinogenesis · doi:10.1002/mc.20588 · Cited by 97 · see citing works

Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas

Minor, J., Wang, X., Zhang, F., et al. (2011) · Oral Oncology · doi:10.1016/j.oraloncology.2011.11.006 · Cited by 91 · see citing works

Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer

Hulf, T., Sibbritt, T., Wiklund, E. D., Patterson, K., Song, J. Z., Stirzaker, C., Qu, W., Nair, S. S., Horvath, L. G., Armstrong, N. J., et al. (2012) · Oncogene · doi:10.1038/onc.2012.300 · Cited by 88 · see citing works

Epigenetic Regulation of miR-212 Expression in Lung Cancer

Incoronato, M., Urso, L., Portela, A., Laukkanen, M. O., Soini, Y., Quintavalle, C., Keller, S., Esteller, M., & Condorelli, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027722 · Cited by 84 · see citing works

A Functional Variant in MicroRNA-196a2 Is Associated with Susceptibility of Colorectal Cancer in a Chinese Population

Zhan, J., Chen, L., Chen, Z., et al. (2011) · Archives of Medical Research · doi:10.1016/j.arcmed.2011.04.001 · Cited by 83 · see citing works

Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma

Gebauer, K., Peters, I., Dubrowinskaja, N., Hennenlotter, J., Abbas, M., Scherer, R., Tezval, H., Merseburger, A., Stenzl, A., Kuczyk, M., et al. (2013) · British Journal of Cancer · doi:10.1038/bjc.2012.537 · Cited by 81 · see citing works

MicroRNAs in cardiac disease

Dorn, G. W. (2011) · Translational research · doi:10.1016/j.trsl.2010.12.013 · Cited by 75 · see citing works

A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma

Permuth‐Wey, J., Thompson, R. C., Nabors, B., et al. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0634-1 · Cited by 73 · see citing works

miRNA genes and the brain: implications for psychiatric disorders a

Forero, D. A., van der Ven, K., Callaerts, P., & Del-Favero, J. (2010) · Human Mutation · doi:10.1002/humu.21344 · Cited by 69 · see citing works

Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes

Duan, S., Mi, S., Zhang, W., & Dolan, M. E. (2009) · RNA Biology · doi:10.4161/rna.6.4.8830 · Cited by 65 · see citing works

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer

Zhang, X., Yang, H., Lee, J. J., et al. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq177 · Cited by 62 · see citing works

MicroRNAs in colorectal cancer: Function, dysregulation and potential as novel biomarkers

Nugent, M., Miller, N., & Kerin, M. J. (2011) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2011.05.005 · Cited by 61 · see citing works

Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma

Corthals, S. L., Jongen‐Lavrencic, M., de Knegt, Y., et al. (2009) · Leukemia Research · doi:10.1016/j.leukres.2009.10.026 · Cited by 60 · see citing works

KRAS mutation, KRAS–LCS6 polymorphism, and non-small cell lung cancer

Nelson, H. H., Christensen, B. C., Plaza, S. L., et al. (2009) · Lung Cancer · doi:10.1016/j.lungcan.2009.09.008 · Cited by 59 · see citing works

Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562

Drake, K. M., Ruteshouser, E. C., Natrajan, R., Harbor, P. C., Wegert, J., Gessler, M., Pritchard‐Jones, K., Grundy, P. E., Dome, J. S., Huff, V., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-1065 · Cited by 58 · see citing works

Methylation mediated silencing of miR-23b expression and its role in glioma stem cells

Geng, J., Luo, H., Pu, Y., Zhou, Z., Wu, X., Xu, W., & Yang, Z. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.08.055 · Cited by 53 · see citing works

Inherited polymorphisms in the RNA-mediated interference machinery affect microRNA expression and lung cancer survival

Rotunno, M., Zhao, Y., Bergen, A. W., Koshiol, J. E., Burdette, L. A., Rubagotti, M., Linnoila, R. I., Marincola, F. M., Bertazzi, P. A., Pesatori, A. C., et al. (2010) · British Journal of Cancer · doi:10.1038/sj.bjc.6605976 · Cited by 49 · see citing works

The miR‐15a‐miR‐16‐1 locus is homozygously deleted in a subset of prostate cancers

Porkka, K. P., Ogg, E.-L., Saramäki, O. R., Vessella, R. L., Pukkila, H., Lähdesmäki, H. J., van Weerden, W. M., Wolf, M., Kallioniemi, O., Jenster, G. W., et al. (2011) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20873 · Cited by 47 · see citing works

miR-205 Expression Levels in Nonsmall Cell Lung CancerDo Not Always Distinguish Adenocarcinomas From Squamous Cell Carcinomas

Vescovo, V. D., Cantaloni, C., Cucino, A., Girlando, S., Silvestri, M., Bragantini, E., Fasanella, S., Cuorvo, L. V., Palma, P., Rossi, G., et al. (2011) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e3182068171 · Cited by 47 · see citing works

Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126

Harnprasopwat, R., Ha, D., Toyoshima, T., et al. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.07.009 · Cited by 46 · see citing works

Characterization of a 7.6-Mb germline deletion encompassing the NF1 locus and about a hundred genes in an NF1 contiguous gene syndrome patient

Pasmant, É., de Saint-Trivier, A., Laurendeau, I., Dieux‐Coëslier, A., Parfait, B., Vidaud, M., Vidaud, D., & Bièche, I. (2008) · European Journal of Human Genetics · doi:10.1038/ejhg.2008.134 · Cited by 32 · see citing works

Increased Number of MicroRNA Target Sites in Genes Encoded in CNV Regions. Evidence for an Evolutionary Genomic Interaction

Felekkis, K. N., Voskarides, K., Dweep, H., et al. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr078 · Cited by 30 · see citing works

A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan

Lin, C., Li, L., Ho, S.-F., et al. (2008) · BMC Genetics · doi:10.1186/1471-2156-9-92 · Cited by 24 · see citing works

A C/T mutation in microRNA target sites in BMP5 gene is potentially associated with fatness in pigs

Shao, G. C., Luo, L. F., Jiang, S. W., et al. (2010) · Meat Science · doi:10.1016/j.meatsci.2010.09.013 · Cited by 21 · see citing works

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

O'Brien, J., Hayder, H., Zayed, Y., & Peng, C. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00402 · Cited by 5,287 · see citing works

emiRIT: a text-mining-based resource for microRNA information

Roychowdhury, D., Gupta, S., Qin, X., Arighi, C. N., & Vijay-Shanker, K. (2021) · Database · doi:10.1093/database/baab031 · Cited by 15 · see citing works

MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact

Kunz, M., Göttlich, C., Walles, T., Nietzer, S., Dandekar, G., & Dandekar, T. (2017) · Tumor Biology · doi:10.1177/1010428317706430 · Cited by 23 · see citing works

MicroRNA-34, microRNA-130, microRNA-148, microRNA-181, microRNA-194 and microRNA-605 expression in colon cancer tissue

Игоревич, А. Д., Afanasyev, S. G., Avgustinovich, A. V., Спирина, Л. В., Ковалева, И. В., Zinnurova, A. B., & Belova, V. A. (2024) · South Russian Journal of Cancer · doi:10.37748/2686-9039-2024-5-1-2

MicroRNA Abnormalities and Their Roles in Lung Cancers

Osada, H. (2009) · Haigan · doi:10.2482/haigan.49.894

Therapeutic modulation of microRNAs

Chau, B., Esau, C. C., Mackenna, D., Neben, S., & Gibson, N. W. (2013) · Drug Discovery Today Therapeutic Strategies · doi:10.1016/j.ddstr.2013.12.002 · Cited by 2 · see citing works

Expression profiles of miRNAs in human pancreatic cancer cell lines

Shineng, Zhang, C. X., Haijun, et al. (2009) · Acta Scientiarum Naturalium Universitatis Sunyatseni