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From Dose to Response: In Vivo Nanoparticle Processing and Potential Toxicity
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“Amorphous nano-silica (SiO2) in alveolar macrophages examined by HRTEM after subchronic inhalation in rats at 27 days post-exposure period had undergone significant in vivo breakdown and transformation [102].”
From Particle toxicology and health - where are we? (2019) · cites this paper as [102]
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“In particular, a portion of the original NPs were partially dissolved and secondary SiO2-reaction zones (precipitates) formed as a result of in vivo processing (also called bioprocessing – see section “The 5Bs” below) as shown in Fig. 5 ([102], previously not published).”
From Particle toxicology and health - where are we? (2019) · cites this paper as [102]
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“Compared to the starting materials, the bioprocessed SiO2 particles showed dissolution patterns (voids/pore formation) and outward growth of reaction zones.”
From Particle toxicology and health - where are we? (2019) · cites this paper as [102]
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Particle toxicology and health - where are we?
Riediker, M., Zink, D., Kreyling, W., Oberdörster, G., Elder, A., Graham, U., Lynch, I., Duschl, A., Ichihara, G., Ichihara, S., et al. (2019) · Particle and Fibre Toxicology · doi:10.1186/s12989-019-0302-8 · Cited by 237
Self-citationKlocke, C., Sherina, V., Graham, U. M., Gunderson, J., Allen, J. L., Sobolewski, M., Blum, J. L., Zelikoff, J. T., & Cory-Slechta, D. A. (2018) · Inhalation Toxicology · doi:10.1080/08958378.2018.1533053 · Cited by 41
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Metadata
- Authors
- Graham, U. M., Jacobs, G., Yokel, R. A., Davis, B. H., Dozier, A. K., Birch, M. E., Tseng, M. T., Oberdörster, G., Elder, A., & DeLouise, L.
- Venue
- Advances in Experimental Medicine and Biology
- Publisher
- Springer International Publishing
- Published
- 2017
- Pages
- 71-100
- ISSN
- 0065-2598
- 2214-8019
- PMC
- PMC6376403
- Cited by
- 59
- References
- 6
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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