The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Adipose Tissue Dysfunction: A Multistep Process
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Adipose tissue expansion can lead to hypoxia, adipocyte cell death, enhanced chemokine secretion, and dysregulation in fatty acid fluxes.
“This expansion can lead to a myriad of effects, including hypoxia, adipocyte cell death, enhanced chemokine secretion, and dysregulation in fatty acid fluxes (8).”
From Adipose tissue remodeling and obesity (2011) · cites this paper as [8]
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Helmlinger, G., Yuan, F., Dellian, M., & Jain, R. K. (1997) · Nature Medicine · doi:10.1038/nm0297-177 · Cited by 1,651
Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation
Hosogai, N., Fukuhara, A., Oshima, K., Miyata, Y., Tanaka, S., Segawa, K., Furukawa, S., Tochino, Y., Komuro, R., Matsuda, M., et al. (2007) · Diabetes · doi:10.2337/db06-0911 · Cited by 1,257 · cited 1×
“As a highly active secretory cell, the adipocyte is prone to an overload of the secretory pathway that can be caused by several different reasons, including hypoxia and/or increased levels of reactive oxygen species ( Hosogai et al. 2007 ).”
BackgroundMinireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis
Rajala, M. W., & Scherer, P. E. (2003) · Endocrinology · doi:10.1210/en.2003-0580 · Cited by 1,204
Self-citationMetabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI
Khan, T., Muise, E. S., Iyengar, P., Wang, Z. V., Chandalia, M., Abate, N., Zhang, B. B., Bonaldo, P., Chua, S., & Scherer, P. E. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01300-08 · Cited by 1,053
Self-citationHypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue
Halberg, N., Khan, T., Trujillo, M. E., Wernstedt-Asterholm, I., Attie, A. D., Sherwani, S., Wang, Z. V., Landskroner-Eiger, S., Dineen, S., Magalang, U. J., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00192-09 · Cited by 896
Self-citationReduced Adipose Tissue Oxygenation in Human Obesity
Pasarica, M., Sereda, O. R., Redman, L. M., Albarado, D. C., Hymel, D. T., Roan, L. E., Rood, J. C., Burk, D. H., & Smith, S. R. (2009) · Diabetes · doi:10.2337/db08-1098 · Cited by 786
The “metabolically-obese,” normal-weight individual
Ruderman, N. B., Schneider, S. H., & Berchtold, P. (1981) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.8.1617 · Cited by 545
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
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Combinatorial roles of nuclear receptors in inflammation and immunity
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Self-citationPajvani, U. B., Trujillo, M. E., Combs, T. P., Iyengar, P., Jelicks, L., Roth, K. A., Kitsis, R. N., & Scherer, P. E. (2005) · Nature Medicine · doi:10.1038/nm1262 · Cited by 322
Self-citationInfluence of body fat content and distribution on variation in metabolic risk
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Diabetes and apoptosis: lipotoxicity
Kusminski, C. M., Shetty, S., Orci, L., Unger, R. H., & Scherer, P. E. (2009) · Apoptosis · doi:10.1007/s10495-009-0352-8 · Cited by 302
Self-citationEndoplasmic Reticulum Stress Markers Are Associated with Obesity in Nondiabetic Subjects
Sharma, N. K., Das, S. K., Mondal, A. K., Hackney, O. G., Chu, W. S., Kern, P. A., Rasouli, N., Spencer, H. J., Yao‐Borengasser, A., & Elbein, S. C. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1001 · Cited by 275
Systemic Fate of the Adipocyte-Derived Factor Adiponectin
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Self-citationVernochet, C., Peres, S. B., Davis, K. E., McDonald, M. E., Qiang, L., Wang, H., Scherer, P. E., & Farmer, S. R. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01899-08 · Cited by 201
Self-citationAdipocyte differentiation induces dynamic changes in NF-κB expression and activity
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Self-citationAn Exploratory Investigation of the Morphology and Biochemistry of Cellulite
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1-Butyryl-Glycerol: A novel angiogenesis factor secreted by differentiating adipocytes
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Biosynthetic regulation of monobutyrin, an adipocyte-secreted lipid with angiogenic activity
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Adipose tissue remodeling and obesity
Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45887 · Cited by 1,941
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Metadata
- Authors
- Sun, K., & Scherer, P. E.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Scherer, Philipp E.
- Venue
- Research and Perspectives in Endocrine Interactions
- Publisher
- Springer Berlin Heidelberg
- Published
- 2010
- Pages
- 67-75
- ISSN
- 1861-2253 (ISSN-L)
- OpenAlex
- W197317350
- Cited by
- 23
- References
- 22
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 2 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 5.58
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Research and perspectives in endocrine interactions (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- adipose tissue dysfunction, obesity, adipocyte hypertrophy, adipocyte hyperplasia, adipose tissue plasticity, extracellular matrix remodeling, adipose tissue vasculature, adipocyte turnover, stromal vascular cells, triglyceride storage, adipose tissue inflammation, metabolic dysfunction
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