Scherer, Philipp E.

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

Berg, A. H., Combs, T. P., Du, X., Brownlee, M., & Scherer, P. E. (2001) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 2,526

Adipose Tissue, Inflammation, and Cardiovascular Disease

Berg, A. H., & Scherer, P. E. (2005) · Circulation Research

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 2,113

Adipose tissue remodeling and obesity

Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,941

Visceral fat adipokine secretion is associated with systemic inflammation in obese humans

Fontana, L., Eagon, J. C., Trujillo, M. E., Scherer, P. E., & Klein, S. (2007) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 1,417

Adipogenesis and metabolic health

Ghaben, A. L., & Scherer, P. E. (2019) · Nature Reviews Molecular Cell Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,395

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

Kim, J.-Y., van de Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Schraw, T., Durand, J. L., Li, H., Li, G., et al. (2007) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,310

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

Wang, Q. A., Tao, C., Gupta, R. K., & Scherer, P. E. (2013) · Nature Medicine

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,262

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

Pajvani, U. B., Hawkins, M., Combs, T. P., Rajala, M. W., Doebber, T., Berger, J. P., Wagner, J. A., Wu, M., Knopps, A., Xiang, A. H., et al. (2004) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,163

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., et al. (2012) · Nature

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 1,136

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

Khan, T., Muise, E. S., Iyengar, P., Wang, Z. V., Chandalia, M., Abate, N., Zhang, B. B., Bonaldo, P., Chua, S., & Scherer, P. E. (2009) · Molecular and Cellular Biology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,053

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

Stern, J. H., Rutkowski, J. M., & Scherer, P. E. (2016) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,031

Fibrosis and adipose tissue dysfunction.

Sun, K., Tordjman, J., Clément, K., & Scherer, P. E. (2013) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 960

Why does obesity cause diabetes?

Klein, S., Gastaldelli, A., Yki-Järvinen, H., & Scherer, P. E. (2022) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesPancreatic function and diabetes

Cited by 939

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Halberg, N., Khan, T., Trujillo, M. E., Wernstedt-Asterholm, I., Attie, A. D., Sherwani, S., Wang, Z. V., Landskroner-Eiger, S., Dineen, S., Magalang, U. J., et al. (2009) · Molecular and Cellular Biology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 896

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

Holland, W. L., Miller, R. A., Wang, Z. V., Sun, K., Barth, B. M., Bui, H. H., Davis, K. E., Bikman, B. T., Halberg, N., Rutkowski, J. M., et al. (2011) · Nature Medicine

Sphingolipid Metabolism and SignalingAdipokines, Inflammation, and Metabolic Diseases

Cited by 892

Adiponectin acts in the brain to decrease body weight

Qi, Y., Takahashi, N., Hileman, S. M., Patel, H. R., Berg, A. H., Pajvani, U. B., Scherer, P. E., & Ahima, R. S. (2004) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 809

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.

Crewe, C., An, Y. A., & Scherer, P. E. (2017) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 732

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

Holland, W. L., Bikman, B. T., Wang, L.-P., Yuguang, G., Sargent, K. M., Bulchand, S., Knotts, T. A., Shui, G., Clegg, D. J., Wenk, M. R., et al. (2011) · Journal of Clinical Investigation

Sphingolipid Metabolism and SignalingAdipokines, Inflammation, and Metabolic Diseases

Cited by 705

Targeting adipose tissue in the treatment of obesity-associated diabetes

Kusminski, C. M., Bickel, P. E., & Scherer, P. E. (2016) · Nature Reviews Drug Discovery

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 678

Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling

Wernstedt Asterholm, I., Tao, C., Morley, T. S., Wang, Q. A., Delgado-Lopez, F., Wang, Z. V., & Scherer, P. E. (2014) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 668

Adiponectin, the past two decades

Wang, Z. V., & Scherer, P. E. (2016) · Journal of Molecular Cell Biology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 609

A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

Combs, T. P., Pajvani, U. B., Berg, A. H., Lin, Y., Jelicks, L. A., Laplante, M., Nawrocki, A. R., Rajala, M. W., Parlow, A. F., Cheeseboro, L., et al. (2004) · Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 545

Sexual Differentiation, Pregnancy, Calorie Restriction, and Aging Affect the Adipocyte-Specific Secretory Protein Adiponectin

Combs, T. P., Berg, A. H., Rajala, M. W., Klebanov, S., Iyengar, P., Jimenez-Chillaron, J. C., Patti, M. E., Klein, S. L., Weinstein, R. S., & Scherer, P. E. (2003) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 544

The cell biology of fat expansion

Rutkowski, J. M., Stern, J. H., & Scherer, P. E. (2015) · Journal of Cell Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 541