The “metabolically-obese,” normal-weight individual

Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance.

National Diabetes Data Group (1979) · Diabetes · doi:10.2337/diab.28.12.1039 · Cited by 4,909 · see citing works

Effect of Weight Loss without Salt Restriction on the Reduction of Blood Pressure in Overweight Hypertensive Patients

Reisin, E., Abel, R., Modan, M., Silverberg, D. S., Eliahou, H. E., & Modan, B. (1978) · New England Journal of Medicine · doi:10.1056/nejm197801052980101 · Cited by 759 · see citing works

Endocrine and Metabolic Effects of Experimental Obesity in Man

Sims, E. A. H., Danforth, E., Horton, E. S., Bray, G. A., Glennon, J. A., & Salans, L. B. (1973) · Elsevier eBooks · doi:10.1016/b978-0-12-571129-6.50016-6 · Cited by 563 · see citing works

Effects of Weight Reduction on Obesity STUDIES OF LIPID AND CARBOHYDRATE METABOLISM IN NORMAL AND HYPERLIPOPROTEINEMIC SUBJECTS

Olefsky, J. M., Reaven, G. M., & Farquhar, J. W. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107560 · Cited by 510 · see citing works

Biliary lipid secretion in cholesterol gallstone disease. The effect of cholecystectomy and obesity.

Shaffer, E. A., & SMALL, D. M. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108705 · Cited by 346 · see citing works

Studies of Human Adipose Tissue ADIPOSE CELL SIZE AND NUMBER IN NONOBESE AND OBESE PATIENTS

Salans, L. B., Cushman, S. W., & Weismann, R. E. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107258 · Cited by 325 · see citing works

Effect of exercise and physical fitness on serum lipids and lipoproteins

Lopez‐S, A., Vial, R., Balart, L., & ARROYAVE, G. (1974) · Atherosclerosis · doi:10.1016/0021-9150(74)90073-2 · Cited by 291 · see citing works

The effect of physical training on insulin production in obesity

Björntorp, P. A., de Jounge, K., Sjöström, L., & Sullivan, L. (1970) · Metabolism · doi:10.1016/0026-0495(70)90020-x · Cited by 281 · see citing works

Relationship of Childhood Weight Status to Morbidity in Adults

Abraham, S., Collins, G., & Nordsieck, M. (1971) · HSMHA Health Reports · doi:10.2307/4594149 · Cited by 271 · see citing works

Effects of long-term physical training on body fat, metabolism, and blood pressure in obesity

Krotkiewski, M., Mandroukas, K., Sjöström, L., Sullivan, L., Wetterqvist, H., & Björntorp, P. A. (1979) · Metabolism · doi:10.1016/0026-0495(79)90018-0 · Cited by 247 · see citing works

Aging and Diabetes

Andres, R. (1971) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)32479-8 · Cited by 232 · see citing works

Carbohydrate and lipid metabolism in middle-aged, physically well-trained men

Björntorp, P. A., Fahlén, M., Grimby, G., Gustafson, A., Holm, J., Renström, P. A. F. H., & Scherstén, T. (1972) · Metabolism · doi:10.1016/0026-0495(72)90034-0 · Cited by 231 · see citing works

Risk Factors for the Development of Cholelithiasis in Man

Bennion, L. J., & Grundy, S. M. (1978) · New England Journal of Medicine · doi:10.1056/nejm197811302992205 · Cited by 196 · see citing works

Glucose Intolerance During Decreased Physical Activity in Man

Lipman, R. L., Raskin, P., Love, T., Triebwasser, J. H., Lecocq, F. R., & Schnure, J. J. (1972) · Diabetes · doi:10.2337/diab.21.2.101 · Cited by 195 · see citing works

Changes of body composition in man during maturity and their nutritional implications.

Brozek, J. M. (1952) · PubMed · Cited by 170 · see citing works

Effect of diet composition on the hyperinsulinemia of obesity

Grey, N., & Kipnis, D. M. (1971) · New England Journal of Medicine · doi:10.1056/nejm197110072851504 · Cited by 156 · see citing works

Bile Acid Kinetics in Relation to Sex, Serum Lipids, Body Weights, and Gallbladder Disease in Patients with Various Types of Hyperlipoproteinemia

Einarsson, K., Hellström, K., & Kallner, M. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107876 · Cited by 126 · see citing works

EFFECTS OF PHYSICAL TRAINING ON GLUCOSE TOLERANCE, PLASMA INSULIN AND LIPIDS AND ON BODY COMPOSITION IN MEN AFTER MYOCARDIAL INFARCTION

Björntorp, P. A., Berchtold, P., Grimby, G., Lindholm, B., Sanne, H., Tibblin, G., & Wilhelmsen, L. (1972) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1972.tb04843.x · Cited by 91 · see citing works

Insulin Secretion in Relation to Adipose Tissue in Men

Björntorp, P. A., Berchtold, P., & Tibblin, G. (1971) · Diabetes · doi:10.2337/diab.20.2.65 · Cited by 91 · see citing works

Insulin and glucose responses during bed rest with isotonic and isometric exercise

Dolkas, C. B., & GREENLEAF, J. E. (1977) · Journal of Applied Physiology · doi:10.1152/jappl.1977.43.6.1033 · Cited by 76 · see citing works

DOES HYPERGLYCÆMIA OR HYPERINSULINÆMIA CHARACTERISE THE PATIENT WITH CHEMICAL DIABETES ?

Reaven, G., Olefsky, J. M., & Farquhar, J. (1972) · The Lancet · doi:10.1016/s0140-6736(72)90977-4 · Cited by 76 · see citing works

GLUCOSE TOLERANCE, AGE, AND CIRCULATING INSULIN

Chlouverakis, C., Jarrett, R. J., & KEEN, H. (1967) · The Lancet · doi:10.1016/s0140-6736(67)92774-2 · Cited by 71 · see citing works

GALLBLADDER DISEASE IN HYPERLIPOPROTEINqMIA

Einarsson, K. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92831-7 · Cited by 70 · see citing works

INSULIN EXCESS AS THE INITIAL LESION IN DIABETES

Jackson, W. P. U., Mieghem, W. V., & Keller, P. (1972) · The Lancet · doi:10.1016/s0140-6736(72)91221-4 · Cited by 66 · see citing works

Hyperinsulinemia and Enlarged Adipocytes in Patients with Endogenous Hyperlipoproteinemia without Obesity or Diabetes Mellitus

Bernstein, R. S., Grant, N., & KIPNIS, D. M. (1975) · Diabetes · doi:10.2337/diab.24.2.207 · Cited by 39 · see citing works

GLUCOSE TOLERANCE, PLASMA LIPIDS AND SERUM INSULIN IN PATIENTS WITH ISCHAEMIC HEART DISEASES

Christiansen, I. S., Deckert, T., Kjerulf, K., Midtgaard, K., & WORNING, H. (1968) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1968.tb02458.x · Cited by 36 · see citing works

The Pattern of Plasma Insulin Response to Glucose in Patients with a Previous Myocardial Infarction—The Respective Effects of Age and Disease

Malherbe, C., Marc De Gasparo, B., Berthet, P., Hertogh, R. D., & Hoet, J. J. (1971) · European Journal of Clinical Investigation · doi:10.1111/eci.1971.1.4.265 · Cited by 30 · see citing works

Studies on the natural history of asymptomatic diabetes in young people

Fajans, S. S., Floyd, J. C., Pek, S., et al. (1973) · Metabolism · doi:10.1016/0026-0495(73)90183-2 · Cited by 21 · see citing works

Evaluation of Age-adjusted Criteria for Potential Diabetes

O’Sullivan, J. B., & Mahan, C. M. (1971) · Diabetes · doi:10.2337/diab.20.12.811 · Cited by 17 · see citing works

Does age affect glucose tolerance?

Gm, R. (1977) · PubMed · Cited by 17 · see citing works

Immunoreactive insulin and glucose response to oral glucose in offspring of patients with endogenous hypertriglyceridaemia

Werbin, B., Tamir, I., Heldenberg, D., et al. (1977) · Clinica Chimica Acta · doi:10.1016/0009-8981(77)90116-4 · Cited by 4 · see citing works

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

Wajchenberg, B. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0415 · Cited by 2,961 · see citing works

Pathophysiology of human visceral obesity: an update

Tchernof, A., & Després, J.-P. (2013) · Physiological Reviews · doi:10.1152/physrev.00033.2011 · Cited by 2,583 · see citing works

Adipose tissue remodeling and obesity

Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45887 · Cited by 1,941 · see citing works

Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

Chait, A., & den Hartigh, L. J. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.00022 · Cited by 1,529 · see citing works

The metabolically obese, normal-weight individual revisited.

Ruderman, N., Chisholm, D., Pi-Sunyer, X., & Schneider, S. (1998) · Diabetes · doi:10.2337/diabetes.47.5.699 · Cited by 893 · see citing works

Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesis

Kalinkovich, A., & Livshits, G. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2016.09.008 · Cited by 882 · see citing works

Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women

Goodpaster, B. H., Krishnaswami, S., Resnick, H., Kelley, D. E., Haggerty, C., Harris, T. B., Schwartz, A. V., Kritchevsky, S., & Newman, A. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.372 · Cited by 619 · see citing works

Association of Weight Status With Mortality in Adults With Incident Diabetes

Carnethon, M. R., De Chavez, P. J. D., Biggs, M. L., Lewis, C. E., Pankow, J. S., Bertoni, A. G., Golden, S. H., Liu, K., Mukamal, K. J., Campbell-Jenkins, B., et al. (2012) · JAMA · doi:10.1001/jama.2012.9282 · Cited by 567 · see citing works

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

Unger, R. H., & Scherer, P. E. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2010.01.009 · Cited by 436 · see citing works

Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

Sun, K., Park, J., Gupta, O. T., Holland, W. L., Auerbach, P., Zhang, N., Goncalves Marangoni, R., Nicoloro, S. M., Czech, M. P., Varga, J., et al. (2014) · Nature Communications · doi:10.1038/ncomms4485 · Cited by 364 · see citing works

NASH in lean individuals

Younes, R., & Bugianesi, E. (2019) · Seminars in Liver Disease · doi:10.1055/s-0038-1677517 · Cited by 235 · see citing works

Metabolic and Behavioral Characteristics of Metabolically Obese but Normal-Weight Women

Conus, F., Allison, D. B., Rabasa-Lhoret, R., St-Onge, M., St-Pierre, D. H., Tremblay-Lebeau, A., & Poehlman, E. T. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0265 · Cited by 215 · see citing works

The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity

O'Connell, J., Lynch, L., Cawood, T. J., Kwasnik, A., Nolan, N., Geoghegan, J., McCormick, A., O'Farrelly, C., & O'Shea, D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009997 · Cited by 211 · see citing works

Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine

Unger, R. H. (2005) · Biochimie · doi:10.1016/j.biochi.2004.11.014 · Cited by 184 · see citing works

Adipose tissue and metabolic syndrome: too much, too little or neither

Grundy, S. M. (2015) · European Journal of Clinical Investigation · doi:10.1111/eci.12519 · Cited by 187 · see citing works

Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients

Mathew, H., Farr, O. M., & Mantzoros, C. S. (2016) · Metabolism · doi:10.1016/j.metabol.2015.10.019 · Cited by 182 · see citing works

The Lipid Accumulation Product and All‐cause Mortality in Patients at High Cardiovascular Risk: A PreCIS Database Study

Ioachimescu, A. G., Brennan, D. M., Hoar, B. M., & Hoogwerf, B. J. (2010) · Obesity · doi:10.1038/oby.2009.453 · Cited by 147 · see citing works

Causes and Consequences of Polycystic Ovary Syndrome: Insights From Mendelian Randomization

Zhu, T., & Goodarzi, M. O. (2022) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab757 · Cited by 126 · see citing works

Body Composition in Asians and Caucasians

Haldar, S., Chia, S. C., & Henry, C. J. (2015) · Advances in Food and Nutrition Research · doi:10.1016/bs.afnr.2015.07.001 · Cited by 100 · see citing works

Intermittent fasting improves hepatic end points in nonalcoholic fatty liver disease: a systematic review and meta-analysis

Lange, M., Nadkarni, D., Martin, L., Newberry, C., Kumar, S., & Kushner, T. (2023) · Hepatology Communications · doi:10.1097/hc9.0000000000000212 · Cited by 49 · see citing works

Adipose Tissue Dysfunction: A Multistep Process

Sun, K., & Scherer, P. E. (2010) · Research and Perspectives in Endocrine Interactions · doi:10.1007/978-3-642-13517-0_6 · Cited by 23 · see citing works

A systematic review of physical activity and nutritional interventions for the management of normal weight and overweight obesity

Jacob, E., Moura, A., & Avery, A. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.08.001 · Cited by 7 · see citing works

Measuring Human Age by Estimating Lifetime Caloric Consumption

Gruber, R. P., & Kalamas, A. D. (1999) · Gerontology · doi:10.1159/000022132 · Cited by 1 · see citing works

The rate and degree of food compensation on alteration of its caloric density in rats.

Sd, S., & Vk, M. (1994) · PubMed · Cited by 1 · see citing works

The influence of the degree of caloric restriction on the formation of skin tumors and hepatomas in mice.

Tannenbaum, A., & Silverstone, H. (1949) · PubMed · Cited by 88 · see citing works

Caloric intake necessary for weight maintenance in anorexia nervosa: nonbulimics require greater caloric intake than bulimics

Kaye, W., Gwirtsman, H. E., Obarzanek, E., George, T., Jimerson, D. C., & Mh, E. (1986) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/44.4.435 · Cited by 68 · see citing works

Pre-exposure to high- versus low-caloric foods: Effects on children's subsequent fruit intake

Coelho, J. S., van den Akker, K., Nederkoorn, C., & Jansen, A. T. M. (2011) · Eating Behaviors · doi:10.1016/j.eatbeh.2011.11.004 · Cited by 8 · see citing works