The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Nicotine and sympathetic neurotransmission
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Peripherally, the sympathoadrenal effects of nicotine are well known, especially those pertaining to acute cardiovascular consequences [24].”
From Nicotine: Sporting Friend or Foe? A Review of Athlete Use, Performance Consequences and Other Considerations (2017) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cryer, P. E., Haymond, M. W., Santiago, J. V., & Shah, S. D. (1976) · New England Journal of Medicine · doi:10.1056/nejm197609092951101 · Cited by 1,101 · cited 2×
“Furthermore, they are markedly attenuated by combined alpha- and beta-adrenoceptor blockade, indicating that the nicotine-evoked cardiovascular effects are mediated by sympathetic activation [9].”
BackgroundBenowitz, N. L., Porchet, H., Sheiner, L., & Jacob, P. (1988) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1988.107 · Cited by 619
Mechanisms responsible for sympathetic activation by cigarette smoking in humans.
Grassi, G., Seravalle, G., Calhoun, D. A., Bolla, G. B., Giannattasio, C., Marabini, M., Del Bo, A., & Mancia, G. (1994) · Circulation · doi:10.1161/01.cir.90.1.248 · Cited by 394 · cited 3×
“This notion is mainly derived from the close relationship between plasma concentrations of nicotine and the cardiovascular effects observed during cigarette smoking [2,12].”
Background
Research works printed but not linked: 52
- Augustine, GJ, Neher, E. Neuronal Ca2+ signalling takes the local route. Curr Opin Neurobiol 1992;2:302?307. · DOI
- Benowitz, NL. Nicotine and coronary heart disease. Trends Cardiovasc Med 1991;1:315?321. · DOI
- Bertrand, D, Galzi, JL, Devillers-Thiery, A, Bertrand, S, Changeux, J-P. Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal ?7 nicotinic receptor. Proc Natl Acad Sci USA 1993;90: 6971?6975. · DOI
- Boksa, P, Livett, BG. Desensitization to nicotinic cholinergic agonists and K+ agents, that stimulate catecholamine secretion, in isolated adrenal chromaffin cells. J Neurochem 1984; 42:607?617. · DOI
- Brooks, JC. The isolated bovine adrenomedullary chromaffin cell: A model of neuronal excitation-secretion. Endocrinology 1977;101:1369?1378. · DOI
- Changeux, J-P. The TiPS lecture. The nicotinic acetylcholine receptor: An allosteric protein prototype of ligand-gated ion channels. Trends Pharmacol Sci 1990;11:485?492. · DOI
- Cheek, TR, Jackson, TR, O'Sullivan, AJ, Moreton, RB, Berridge, MJ, Burgoyne, MJ, Burgoyne, RD. Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in cocultured cells. J Cell Biol 1989;109:1219?1227. · DOI
- Deanfield, JE, Shea, MJ, Wilson, RA, Horlock, P, deLandsheere, CM, Selwyn, AP. Direct effects of smoking on the heart: Silent ischemic disturbances of coronary flow. Am J Cardiol 1986;57:1005?1009. · DOI
- Gerber, SH, Haunstetter, A, Krüger, C, Kaufmann, A, Nobiling, R, Haass, M. Role of [Na+]i and [Ca2+]i in nicotine-induced norepinephrine release from bovine adrenal chromaffin cells. Am J Physiol 1995;269(Cell Physiol 38): C572-C581. · DOI
- Haass, M, Hock, M, Richardt, G, Schömig, A. Neuropeptide Y differentiates between exocytotic and nonexocytotic noradrenaline release in guinea-pig heart. Naunyn-Schmiedebergs Arch Pharmacol 1989;340:509?515. · DOI
- Haass, M, Förster, C, Richardt, G, Kranzhöfer, R, Schömig, A. Role of calcium channels and protein kinase C for release of norepinephrine and neuropeptide Y. Am J Physiol 1990; 259 (Regulatory Integrative Comp Physiol 28):R925-R930.
- Haass, M, Richardt, G, Brenn, T, Schömig, E, Schömig, A. Nicotine-induced release of noradrenaline and neuropeptide Y in guinea-pig heart: Role of calcium channels and protein kinase C. Naunyn-Schmiedebergs Arch Pharmacol 1991; 344:527?531. · DOI
- Haass, M, Richardt, G, Schömig, A. Potentiation of potassium-evoked noradrenaline and neuropeptide Y co-release by cardiac energy depletion: Role of calcium channels and sodium-proton exchange. Naunyn-Schmiedebergs Arch Pharmacol 1992;346:410?418. · DOI
- Haass, M, Serf, C, Krüger, C, Haunstetter, A, Vahl, Ch-F, Kübler, W. Digitalis glycosides stimulate norepinephrine release from the human heart by a dual mechanism of action (abstr). Eur Heart J 1994;15(Suppl):173.
- Haeusler, G, Thoenen, H, Haefely, W, Huerlimann, A. Electrical events in cardiac adrenergic nerves and noradrenaline release from the heart induced by acetylcholine and KCl. Naunyn-Schmiedebergs Arch Pharmacol Exp Path 1968; 261:389?411. · DOI
- Hallstrom, AP, Cobb, LA, Ray, R. Smoking as a risk factor for recurrence of sudden cardiac arrest. N Engl J Med 1986; 314:271?275. · DOI
- Haunstetter, A, Haass, M, Yi, X, Krüger, C, Kübler, W. Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischaemia and reperfusion. Am J Physiol 1994;267 (Regulat Integrat Physiol 36):R1552-R1558.
- Hernandez-Cruz, A, Salia, F, Adams, PR. Subcellular calcium transients visualized by confocal microscope in a voltage-clamped neuron. Science 1990;247:858?862. · DOI
- Kao, L-S, Schneider, AS. Calcium mobilization and catecholamine secretion in adrenal chromaffin cells. J Biol Chem 1986;261:4881?4888. · DOI
- Karlin, A. Structure of nicotinic acetylcholine receptors. Curr Opin Neurobiol 1993;3:299?309. · DOI
- Kilpatrick, DL, Slepetis, R, Kirshner, N. Ion channels and membrane potential in stimulus-secretion coupling in adrenal medulla cells. J Neurochem 1981;36:1245?1255. · DOI
- Klein, LW, Ambrose, J, Pichard, A, Holt, J, Gorlin, R, Teichholz, LE. Acute coronary hemodynamic response to cigarette smoking in patients with coronary artery disease. J Am Coll Cardiol 1984;3:879?886. · DOI
- Knopf, H, Theissing, R, Hirche, H. Continuous determination of extracellular space and changes in K+, Na+, Ca2+, and H+ during global ischemia in isolated rat hearts. J Mol Cell Cardiol 1990;22:1259?1272. · DOI
- Kottke, TE. Smoking cessation therapy for the patient with heart disease. J Am Coll Cardiol 1993;22:1168?1169. · DOI
- Krüger, C, Haunstetter, A, Gerber, S, Serf, C, Kaufmann, A, Kübler, W, Haass, M. Nicotine-induced exocytotic norepinephrine release in guinea-pig heart, human atrium and bovine adrenal chromaffin cells: Modulation by single components of ischemia. J Mol Cell Cardiol 1995;27:1491?1506. · DOI
- Kübler, W, Haass, M. Cardioprotection: Definition, classification, and fundamental principles. Heart 1996;75:330?333. · DOI
- Kurz, T, Richard, G, Hagl, S, Seyfarth, M, Schömig, A. Two different mechanisms of noradrenaline release during normoxia and simulated ischemia in human cardiac tissue. J Mol Cell Cardiol 1995;27:1161?1172. · DOI
- Löffelholz, K. Autoinhibition of nicotinic release of noradrenaline from postganglionic sympathetic nerves. Naunyn-Schmiedebergs Arch Pharmacol 1970;267:49?63. · DOI
- Löffelholz, K. Release induced by nicotinic agents. In: Paton, DM, ed. The Release of Catecholamines from Adrenergic Neurons. Oxford: Pergamon Press, 1979:275?301. · DOI
- McKenna, WJ, Chew, CY, Oakley, CM. Myocardial infarction with normal coronary angiogram: Possible mechanisms of smoking risk in coronary artery disease. Br Heart J 1980; 43:493?498. · DOI
- Moliterno, DJ, Willard, JE, Lange, RA, et al. Coronary-artery vasoconstriction induced by cocaine, cigarette smoking, or both. N Engl J Med 1994;330:454?459. · DOI
- Nooney, JM, Peters, JA, Lambert, JJ. A patch clamp study of the nicotinic acetylcholine receptor of adrenomedullary chromaffin cells in culture. J Physiol 1992;455:503?527. · DOI
- Richardt, G, Haass, M, Neeb, S, Hock, M, Lang, RE, Schömig, A. Nicotine-induced release of noradrenaline and neuropeptide Y in guinea pig heart. Klin Wochenschr 1988;66(Suppl XI):21?27.
- Richardt, G, Brenn, T, Seyfarth, M, Haass, M, Schömig, E, Schömig, A. Dual effect of nicotine on cardiac noradrenaline release during metabolic blockade. Basic Res Cardiol 1994; 89:524?534. · DOI
- Robertson, D, Tseng, C-J, Appalsamy, M. Smoking and mechanisms of cardiovascular control. Am Heart J 1988; 115:258?262. · DOI
- Role, LW. Diversity in primary structure and function of neuronal nicotinic acetylcholine receptor channels. Curr Opinion Neurobiol 1992;4:254?262. · DOI
- Rosenberg, J, Benowitz, NL, Gacob, P, Wilson, M. Disposition kinetics and effects of intravenous nicotine. Clin Pharmacol Ther 1980;28:517?522. · DOI
- Rosenberg, L, Kaufman, DW, Helmrich, SP, Shapiro, S. The risk of myocardial infarction after quitting smoking in men under 55 years of age. N Engl J Med 1985;313:1511?1514. · DOI
- Rosenberg, L, Palmer, JR, Shapiro, S. Decline in the risk of myocardial infarction among women who stop smoking. N Engl J Med 1990;322:213?217. · DOI
- Sargent, PB. The diversity of neuronal nicotinic acetylcholine receptors. Ann Rev Neurosci 1993;16:403?443. · DOI
- Schömig, A, Dart, AM, Dietz, R, Mayer, E, Kübler, W. Release of endogenous catecholamines in the ischemic myocardium of the rat. Part A: Locally mediated release. Circ Res 1984;55:689?701. · DOI
- Schömig, A, Haass, M, Richardt, G. Catecholamines and arrhythmias in acute myocardial ischemia. Eur Heart J 1991; 12(Suppl F):38?47. · DOI
- Seyfarth, M, Feng, Y, Hagl, S, Sebening, F, Richardt, G, Schömig, A. Effect of myocardial ischemia on stimulation-evoked noradrenaline release. Modulated neurotransmission in rat, guinea pig, and human cardiac tissue. Circ Res 1993;73:496?502. · DOI
- Sugiishi, M, Takatsu, F. Cigarette smoking is a major risk factor for coronary spasm. Circulation 1993;87:76?69. · DOI
- Su, C, Bevan, JA. Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine. J Pharmacol Exp Ther 1970;175:533?540.
- Tsien, RY. Fluorescent probes of cell signalling. Ann Rev Neurosci 1989;12:227?253. · DOI
- Unwin, N. Neurotransmitter action: Opening of ligandgated ion channels. Cell 1993;72(Suppl):31?41. · DOI
- Verninino, S, Amador, M, Luetje, CW, Patrick, J, Dani, JA. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 1992;8: 127?134. · DOI
- Wada, A, Takara, H, Izumi, F, Kobashi, H, Yanagihara, N. Influx of 22Na through acetylcholine receptor-associated Na channels: Relationship between 22Na influx, 45Ca influx and secretion of catecholamines in cultured bovine adrenal medulla cells. Neuroscience 1985;15:283?292. · DOI
- Westfall, TC, Brasted, M. The mechanism of action of nicotine on adrenergic neurons in the perfused guinea-pig heart. J Pharmacol Exp Ther 1972;182:409?418.
- Willett, WC, Green, A, Stampfer, MJ, et al. Relative and absolute excess risks of coronary heart disease among women who smoke. N Engl J Med 1987;317:1303?1309. · DOI
- Winniford, MD, Wheelan, KR, Kremers, MS, et al. Smoking-induced coronary vasoconstriction in patients with atherosclerotic coronary artery disease: Evidence for adrenergically mediated alterations in coronary artery tone. Circulation 1986;73:662?667. · DOI
Cited by
Autonomic innervation and regulation of the immune system (1987–2007)
Nance, D. M., & Sanders, V. M. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.03.008 · Cited by 855
Chamberlain, A. M., Agarwal, S. K., Folsom, A. R., Duval, S., Soliman, E. Z., Ambrose, M., Eberly, L. E., & Alonso, A. (2011) · Heart Rhythm · doi:10.1016/j.hrthm.2011.03.038 · Cited by 284
Richards, J. M., Stipelman, B. A., Bornovalova, M. A., Daughters, S. B., Sinha, R., & Lejuez, C. W. (2011) · Biological Psychology · doi:10.1016/j.biopsycho.2011.06.009 · Cited by 132
Orzabal, M. R., Lunde-Young, E. R., Ramirez, J. I., Howe, S. Y. F., Naik, V. D., Lee, J., Heaps, C. L., Threadgill, D. W., & Ramadoss, J. (2019) · Translational Research · doi:10.1016/j.trsl.2019.01.001 · Cited by 91
“Nicotine has been shown to possess strong vasoconstrictor properties, and acts by stimulating sympathetic outflow and impairing endothelial-dependent vasorelaxation, effectively increasing the vascular resistance in the feto-placental compartment.(68,69) A lower blood volume per unit time delivered to the feto-placent…”
Pest Control Agents from Natural Products
Ujváry, I. (2010) · Hayes' Handbook of Pesticide Toxicology · doi:10.1016/b978-0-12-374367-1.00003-3 · Cited by 81
Metadata
- Authors
- Haass, M., & K�bler, W.
- Venue
- Cardiovascular Drugs and Therapy
- Published
- 1997-01
- Volume
- 10
- Issue
- 6
- Pages
- 657-665
- ISSN
- 0920-3206
- 1573-7241
- Cited by
- 233
- References
- 3
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.