Evolution of the genetic code
Integrity signals
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The translation system is ancient and highly conserved, and it must have started with protobiopolymers.
“The translation system is ancient and highly conserved, and it must have started with protobiopolymers [41,64,65,66,67].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [64]
The remaining ten amino acids are derivatives of the first ten primitive amino acids.
“The remaining ten amino acids are derivatives of the first ten primitive amino acids.”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [64]
The SNS type code shares similarity with the Phase 1 amino acids that were generated in prebiotic synthesis.
“The SNS type code shares similarity with the Phase 1 amino acids that were generated in prebiotic synthesis [64].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [64]
The genetic code and the translation mechanism evolved together in the prebiotic world.
“We concur with the view that the genetic code and the translation mechanism evolved together in the prebiotic world [64].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [64]
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- Authors
- Woese, C. R.
- Affiliations
- University of Illinois Urbana-Champaign (US)
- Corresponding author
- Woese, C. R.
- Venue
- The Science of Nature
- Published
- 1973-10
- Volume
- 60
- Issue
- 10
- Pages
- 447-459
- ISSN
- 0028-1042 (ISSN-L)
- 1432-1904
- OpenAlex
- W2083627310
- Cited by
- 141
- References
- 58
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 2 · 2020: 7 · 2019: 5 · 2018: 5 · 2017: 10 · 2016: 4 · 2015: 5 · 2014: 5 · 2013: 5 · 2012: 2
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Die Naturwissenschaften (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- genetic code, origin of the genetic code, codon evolution, molecular evolution
- MeSH terms
- Amino Acids, Base Sequence, Binding Sites, Biological Evolution, Genes, Genetic Code, Models, Structural, Molecular Biology, Mutation, Nucleic Acid Conformation, Phenotype, Protein Binding, Ribosomes, RNA, Ribosomal, RNA, Transfer, Suppression, Genetic, Protein Biosynthesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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