The mechanism of arrest of neuronal migration in the Zellweger malformation: An hypothesis based upon cytoarchitectonic analysis
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In patients with Zellweger syndrome, the most prominent feature of brain pathology is malformation of the cortex, attributed to neuronal migration defects.
“In patients with Zellweger syndrome, the most prominent feature of the brain pathology is a malformation of the cortex, which has been attributed to neuronal migration defects.”
From Peroxisomes in brain development and function (2016) · cites this paper as [50]
The abnormalities in cytoarchitecture of the cerebral cortex in Zellweger syndrome are usually bilateral and approximately symmetrical.
“The abnormalities in the cytoarchitecture of the cerebral cortex are usually bilateral and approximately symmetrical [49,50].”
From Peroxisomes in brain development and function (2016) · cites this paper as [50]
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- Authors
- Evrard, P., Caviness, V. S., Prats-Vinas, J., & Lyon, G.
- Affiliations
- Harvard University (US)
- Venue
- Acta Neuropathologica
- Published
- 1978-01
- Volume
- 41
- Issue
- 2
- Pages
- 109-117
- ISSN
- 0001-6322 (ISSN-L)
- 1432-0533
- OpenAlex
- W2060840571
- Cited by
- 175
- References
- 29
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 5 · 2017: 2 · 2015: 3 · 2012: 2
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Acta Neuropathologica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Fetal and Pediatric Neurological Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neuronal heterotopia, cerebellar cortex, inferior olive, cortical lamination, cytoarchitecture
- MeSH terms
- Abnormalities, Multiple, Brain, Cell Movement, Cerebellar Cortex, Cerebellum, Cerebral Cortex, Humans, Infant, Male, Neurons, Purkinje Cells, Syndrome
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