The effects of caffeine on ambulatory blood pressure, heart rate, and mood in coffee drinkers
Abstract
The present study examined the effects of caffeine, as typically ingested through coffee, on ambulatory systolic and diastolic blood pressure (BP), heart rate, and mood. Normotensive coffee drinkers wore a BP monitor for two 24-hr periods, consuming decaffeinated coffee. Each cup was supplemented with 125 mg caffeine or cornstarch. Systolic and diastolic BPs were elevated on the day caffeine was consumed (maximum, 3.6 and 5.6 mm Hg, respectively), most notably shortly after ingestion. Heart rate was higher overnight following caffeine consumption. Negative Affectivity was also increased by caffeine, but Positive Affectivity and tiredness were unaffected.
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Tolerance to caffeine's more arousing effects did not develop.
“This would suggest that tolerance to caffeine's more arousing effects did not develop although this is in contrast to Green & Suls' study [31].”
From Central and peripheral effects of sustained caffeine use: tolerance is incomplete (2002) · cites this paper as [31]
Chronic caffeine consumption is associated with increased anxiety, tension, restlessness, nervousness and anger.
“It has been demonstrated with free-living and laboratory studies that chronic caffeine consumption is associated with increased anxiety, tension, restlessness, nervousness and anger [29][30][31].”
From Central and peripheral effects of sustained caffeine use: tolerance is incomplete (2002) · cites this paper as [31]
Cites
Development and validation of brief measures of positive and negative affect: The PANAS scales.
Watson, D., Clark, L. A., & Tellegen, A. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.6.1063 · Cited by 32,433 · see citing works
Toward a consensual structure of mood.
Watson, D., & Tellegen, A. (1985) · Psychological bulletin · doi:10.1037/0033-2909.98.2.219 · Cited by 5,362 · see citing works
Ethical principles of psychologists and code of conduct
American Psychological Association (1992) · American Psychologist · doi:10.1037/0003-066x.47.12.1597 · Cited by 1,362 · see citing works
Toward a consensual structure of mood
Watson, D., & Tellegen, A. (1985) · Psychological Bulletin · doi:10.1037//0033-2909.98.2.219 · Cited by 1,170 · see citing works
Effects of Caffeine on Plasma Renin Activity, Catecholamines and Blood Pressure
Robertson, D., Frölich, J. C., Carr, R. K., Watson, J. T., Hollifield, J. W., Shand, D. G., & Oates, J. A. (1978) · New England Journal of Medicine · doi:10.1056/nejm197801262980403 · Cited by 757 · see citing works
(1979) · JAMA · doi:10.1001/jama.242.23.2562 · Cited by 503 · see citing works
Tolerance to the humoral and hemodynamic effects of caffeine in man.
Robertson, D., Wade, D., Workman, R., Woosley, R. L., & Oates, J. A. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110124 · Cited by 501 · cited 2× · see citing works
“Considerations about tolerance also obscure whether caffeine, as it is used naturally, affects BP Tolerance to the BP effects of caffeine has been demonstrated ( Robertson et al., 1981 ), resulting in little or no BP increase after repeated use.”
BackgroundWatson, D. (1988) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.55.1.128 · Cited by 475 · see citing works
Clinical Pharmacology Of Caffeine
Benowitz, N. L. (1990) · Annual Review of Medicine · doi:10.1146/annurev.me.41.020190.001425 · Cited by 441 · see citing works
Watson, D. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.55.1.128 · Cited by 323 · see citing works
Effect of smoking on caffeine clearance
Parsons, W. D., & Neims, A. H. (1978) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt197824140 · Cited by 302 · see citing works
Caffeine physical dependence: a review of human and laboratory animal studies
Griffiths, R. R., & Woodson, P. P. (1988) · Psychopharmacology · doi:10.1007/bf00212836 · Cited by 276 · cited 1× · see citing works
“Perhaps the length of the study was not sufficient to allow for development of withdrawal symptoms ( Griffiths and Woodson, 1988 ).”
BackgroundCaffeine content of beverages as consumed.
Gilbert, R. M., Marshman, J. A., Schwieder, M., & Berg, R. (1976) · PubMed Central · Cited by 175 · see citing works
Effects of caffeine on alertness
Zwyghuizen‐Doorenbos, A., Roehrs, T., Lipschutz, L., Timms, V., & Roth, T. G. (1990) · Psychopharmacology · doi:10.1007/bf02245786 · Cited by 173 · see citing works
Effects of caffeine on mood and memory
Loke, W. H. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90039-x · Cited by 163 · see citing works
Effects of caffeine on vascular resistance, cardiac output and myocardial contractility in young men
Pincomb, G. A., Lovallo, W. R., Passey, R. B., Whitsett, T. L., Silverstein, S. M., & Wilson, M. F. (1985) · The American Journal of Cardiology · doi:10.1016/0002-9149(85)90578-8 · Cited by 137 · see citing works
Low-dose caffeine discrimination in humans.
Griffiths, R. R., Evans, S. M., Heishman, S. J., Preston, K. L., Sannerud, C. A., Wolf, B., & Woodson, P. P. (1990) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20216-6 · Cited by 133 · see citing works
Ad lib caffeine consumption, symptoms of caffeinism, and academic performance
Gilliland, K., & Andress, D. (1981) · American Journal of Psychiatry · doi:10.1176/ajp.138.4.512 · Cited by 121 · see citing works
Renal and cardiovascular effects of caffeine: a dose-response study
Passmore, A. P., Kondowe, G. B., & Johnston, G. D. (1987) · Clinical Science · doi:10.1042/cs0720749 · Cited by 107 · see citing works
Pharmacokinetic-pharmacodynamic modeling of caffeine: tolerance to pressor effects.
Shi, J., Benowitz, N. L., Denaro, C. P., & Sheiner, L. B. (1993) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1993.3 · Cited by 99 · see citing works
Charney, D. S., Galloway, M. P., & Heninger, G. R. (1984) · Life Sciences · doi:10.1016/0024-3205(84)90132-2 · Cited by 95 · see citing works
Dusseldorp, M., & Katan, M. B. (1990) · BMJ · doi:10.1136/bmj.300.6739.1558 · Cited by 92 · see citing works
Casiglia, E., Bongiovi, S., Paleari, C. D., Petucco, S., Boni, M., COLANGELI, G., Penzo, M., & Pessina, A. C. (1991) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1991.tb00385.x · Cited by 87 · see citing works
Effects of caffeine on blood pressure response during exercise in normotensive healthy young men
Sung, B. H., Lovallo, W. R., Pincomb, G. A., & Wilson, M. F. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)91435-9 · Cited by 81 · cited 1× · see citing works
“Any time BP is substantially elevated over normal levels, such as in hypertensives or during strenuous aerobic exercise (see Sung et al., 1990 ), caffeine may have negative consequences.”
BackgroundAnxiety and Muscle Tension as Consequences of Caffeine Withdrawal
White, B. C., Lincoln, C., Pearce, N. W., Reeb, R., & Vaida, C. (1980) · Science · doi:10.1126/science.7433978 · Cited by 77 · see citing works
REINFORCING EFFECTS OF CAFFEINE IN COFFEE AND CAPSULES
Griffiths, R. R., Bigelow, G. E., & Liebson, I. A. (1989) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1989.52-127 · Cited by 76 · see citing works
LOW‐DOSE CAFFEINE DISCRIMINATION AND SELF‐REPORTED MOOD EFFECTS IN NORMAL VOLUNTEERS
Silverman, K., & Griffiths, R. R. (1992) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1992.57-91 · Cited by 74 · see citing works
Caffeine and Cardiovascular Responses to Stress
Lane, J. D. (1983) · Psychosomatic Medicine · doi:10.1097/00006842-198310000-00008 · Cited by 65 · see citing works
Effect of decaffeinated versus regular coffee on blood pressure. A 12-week, double-blind trial.
Dusseldorp, M., Smits, P., Thien, T. A., & Katan, M. (1989) · Hypertension · doi:10.1161/01.hyp.14.5.563 · Cited by 63 · see citing works
Cardiovascular Effects of Caffeine and Stress in Regular Coffee Drinkers
Lane, J. D., & Williams, R. B. (1987) · Psychophysiology · doi:10.1111/j.1469-8986.1987.tb00271.x · Cited by 63 · see citing works
Coffee consumption and blood pressure: an Italian study.
Periti, M., Salvaggio, A., Quaglia, G., & Di Marzio, L. (1987) · Clinical Science · doi:10.1042/cs0720443 · Cited by 58 · see citing works
Persistent increase in caffeine concentrations in people who stop smoking.
Benowitz, N. L., Hall, S. M., & Modin, G. W. (1989) · BMJ · doi:10.1136/bmj.298.6680.1075 · Cited by 56 · see citing works
Snaith, R. P. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.138.6.512 · Cited by 55 · see citing works
(1973) · Behavior Therapy · doi:10.1016/s0005-7894(73)80145-5 · Cited by 50 · see citing works
Relationship between mood and blood pressure in the natural environment: An adolescent population.
Southard, D. R., Coates, T. J., Kolodner, K. B., Parker, F., Padgett, N. E., & Kennedy, H. L. (1986) · Health Psychology · doi:10.1037//0278-6133.5.5.469 · Cited by 49 · see citing works
The Effects of Caffeine on Blood Pressure in the Work Environment
Jeong, D., & Dimsdale, J. E. (1990) · American Journal of Hypertension · doi:10.1093/ajh/3.10.749 · Cited by 45 · see citing works
The Effect of Caffeine on Daytime Ambulatory Blood Pressure
Myers, M. G., & Reeves, R. A. (1991) · American Journal of Hypertension · doi:10.1093/ajh/4.5.427 · Cited by 45 · see citing works
Caffeine restriction: effect on mild hypertension.
MacDonald, T. M., Sharpe, K., Fowler, G., Lyons, D., Freestone, S., Lovell, H. G., Webster, J., & Petrie, J. C. (1991) · BMJ · doi:10.1136/bmj.303.6812.1235 · Cited by 44 · see citing works
Persistent cardiovascular effects with repeated caffeine administration.
Lane, J. D., & Manus, D. C. (1989) · Psychosomatic Medicine · doi:10.1097/00006842-198907000-00001 · Cited by 44 · see citing works
Central nervous system pharmacology of the dietary methylxanthines.
Hirsh, K. R. (1984) · PubMed · Cited by 43 · see citing works
Relationship between mood and blood pressure in the natural environment: An adolescent population.
Southard, D. R., Coates, T. J., Kolodner, K. B., et al. (1986) · Health Psychology · doi:10.1037/0278-6133.5.5.469 · Cited by 43 · see citing works
Casiglia, E., Paleari, C. D., Petucco, S., Bongiovi, S., COLANGELI, G., Baccilieri, M. S., Pavan, L., Pernice, M., & Pessina, A. C. (1992) · PubMed · Cited by 38 · see citing works
Lovallo, W. R., Pincomb, G. A., Sung, B. H., Everson‐Rose, S. A., Passey, R. B., & Wilson, M. F. (1991) · Health Psychology · doi:10.1037//0278-6133.10.4.236 · Cited by 38 · see citing works
Boiled coffee and blood pressure. A 14-week controlled trial.
Dusseldorp, M., Smits, P., Lenders, J. W. M., Thien, T. A., & Katan, M. (1991) · Hypertension · doi:10.1161/01.hyp.18.5.607 · Cited by 37 · see citing works
Effect of coffee on ambulatory blood pressure in patients with treated hypertension
Eggertsen, R., Andreasson, Å., Hedner, T., Karlberg, B. E., & Hansson, L. (1993) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1993.tb00683.x · Cited by 33 · see citing works
Superko, H. R., Myll, J., DiRicco, C., Williams, P. T., Bortz, W. M., & Wood, P. D. (1994) · The American Journal of Cardiology · doi:10.1016/0002-9149(94)90881-8 · Cited by 30 · see citing works
Lovallo, W. R., Pincomb, G. A., Sung, B. H., et al. (1991) · Health Psychology · doi:10.1037/0278-6133.10.4.236 · Cited by 30 · see citing works
Caffeine effects on several indices of cardiovascular activity at rest and during stress
France, C. R., & Ditto, B. (1988) · Journal of Behavioral Medicine · doi:10.1007/bf00844840 · Cited by 25 · see citing works
Use habits among adults of cigarettes, coffee, aspirin, and sleeping pills.
Bonham, G. S., & Leaverton, P. E. (1979) · PubMed · Cited by 22 · see citing works
Cardiovascular responses to occupational stress and caffeine in telemarketing employees.
France, C., & Ditto, B. (1989) · Psychosomatic Medicine · doi:10.1097/00006842-198903000-00004 · Cited by 20 · see citing works
Effects of repeated caffeine administration on cognition and mood
Loke, W. H. (1990) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470050406 · Cited by 20 · see citing works
Seventh International Caffeine Workshop, Santorini, Greece 13–17 June 1993
Barone, J., & Grice, H. C. (1994) · Food and Chemical Toxicology · doi:10.1016/0278-6915(84)90039-5 · Cited by 16 · see citing works
Overview of the methylxanthine beverages and foods and their effect on health.
Spiller, G. A. (1984) · PubMed · Cited by 9 · see citing works
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Smith, A. (2002) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(02)00096-0 · Cited by 741 · see citing works
The effects of red bull energy drink on human performance and mood
Alford, C., Cox, H., & Wescott, R. (2001) · Amino Acids · doi:10.1007/s007260170021 · Cited by 403 · see citing works
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Nurminen, M.-L., Niittynen, L., Korpela, R., & Vapaatalo, H. (1999) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600899 · Cited by 351 · see citing works
James, J. E. (2004) · Psychosomatic Medicine · doi:10.1097/10.psy.0000107884.78247.f9 · Cited by 232 · see citing works
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Pieper, S., Brosschot, J. F., van der Leeden, R., & Thayer, J. F. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181dbc0e9 · Cited by 136 · see citing works
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Central and peripheral effects of sustained caffeine use: tolerance is incomplete
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- Authors
- Green, P. J., & Suls, J.
- Affiliations
- University of Iowa (US)
- ORCID
- Suls, Jerry
- Venue
- Journal of Behavioral Medicine
- Published
- 1996-04
- Volume
- 19
- Issue
- 2
- Pages
- 111-128
- ISSN
- 0160-7715 (ISSN-L)
- 1573-3521
- OpenAlex
- W2050506875
- Semantic Scholar
- 303b5752f2dd9751a3e3eebd2655f8d695a0a576
- Cited by
- 84
- References
- 54
- Citations by year
- 2026: 1 · 2023: 6 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 4 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 6
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Behavioral Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01hl046448-04)
- National Heart, Lung, and Blood Institute (HL-46448)
- Topics
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- caffeine, coffee consumption, ambulatory blood pressure, heart rate, mood, negative affectivity, positive affectivity, fatigue, decaffeinated coffee, normotensive subjects
- MeSH terms
- Adult, Affect, Blood Pressure, Caffeine, Circadian Rhythm, Coffee, Double-Blind Method, Heart Rate, Humans, Male, Personality Inventory, Blood Pressure Monitors
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