The development and function of regulatory T cells

PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer

Hartkopf, A. D., Taran, F., Wallwiener, M., Walter, C. B., Krämer, B., Grischke, E., & Brucker, S. Y. (2016) · Breast Care · doi:10.1159/000453569 · Cited by 30,989

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Park, J., Adoro, S., Guinter, T. I., Erman, B., Alag, A., Catálfamo, M., Kimura, M. Y., Cui, Y., Lucas, P. J., Gress, R. E., et al. (2010) · Nature Immunology · doi:10.1038/ni.1840 · Cited by 5,835

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., & Toda, M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.3.1151 · Cited by 5,608

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., et al. (2004) · Nature Medicine · doi:10.1038/nm1093 · Cited by 5,151

IL-17 and th17 cells

Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

Chen, W., Jin, W., Hardegen, N. J., Lei, K.-J., Li, L., Marinos, N. J., McGrady, G., & Wahl, S. M. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030152 · Cited by 4,678

Interleukin-10-deficient mice develop chronic enterocolitis

Kühn, R., Löhler, J., Rennick, D. M., Rajewsky, K., & Müller, W. (1993) · Cell · doi:10.1016/0092-8674(93)80068-p · Cited by 4,248

Association of CD4+ CD25+ FOXP3+ regulatory T-cells and human papilloma virus infection in Egyptian Women with breast cancerPreprint

Tawfeik, A. M., Mora, A., Osman, A. A. F., Elsheikh, N., & Elrefaei, M. (2020) · doi:10.21203/rs.2.17376/v2

T-Helper Polarization: Regulation by Noncoding RNA and Super-Enhancers

Gibbons, H. R. (2019)

Common Psychological Disorder among Patients with Retroviral Disease

Jaris, N. H., Chidambaram, S. K., Badeshae, S. K., & Razali, S. (2021) · Journal of ASIAN Behavioural Studies · doi:10.21834/jabs.v6i18.380

Regulatory T Cells in Tolerance and Autoimmunity

Wheeler, K. M. (2010) · doi:10.18130/v35276

Effects of Vitamin D in the Immune System

Azizi-Semrad, U., Pietschmann, P., & Willheim, M. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0520-7_4

Molecular linking of HIPEC (Hyperthermic Intraperitoneal Chemotherapy) and T-regulatory cells (FOXp3) and Th-17 (RORɣ) in advanced epithelial ovarian cancer

Ray, M. D., Deo, S. V. S., Luthra, K., Mathur, S. R., Anand, P., Kumar, R., Sharma, S., Kahol, S., & Wahid, A. (2022) · Clinical Immunology Communications · doi:10.1016/j.clicom.2022.03.005

Faculty Opinions recommendation of IL-35-mediated induction of a potent regulatory T cell population.

Engwerda, C. R. (2010) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.5685958.7389054

Esclerose múltipla

von Glehn, F. (2010) · doi:10.47749/t/unicamp.2010.773106

Comparison of intestinal APC subsets from homeostatic and immunostimulatory environments

Hilligan, K. L. (2014) · doi:10.26686/wgtn.17007781.v1

Efeito do interferon tipo I na indução da função tolerogênica das células dendríticas plasmocitóides na encefalomielite experimental autoimune

Santos, M. P. A. (2014) · doi:10.47749/t/unicamp.2014.950287

Estudo das subpopulações de linfócitos B dos pacientes com neuromielite óptica

Andrade, M. (2015) · doi:10.47749/t/unicamp.2015.965675

Role of CD4+ CD25+ FOXP3+ regulatory T-cells and human papilloma virus infection in Egyptian Women with breast cancerPreprint

Tawfeik, A. M., Mora, A., Osman, A. G. E.-D., El-Sheikh, N., & Elrefaei, M. (2019) · doi:10.21203/rs.2.17376/v1

Dynamics of regulatory T cells in lung transplant patients

de Silva, A. T. A. (2022) · Queensland University of Technology · doi:10.5204/thesis.eprints.230504

Molecular Therapy in Myasthenia Gravis

Gomathy, S. B., Agarwal, A., & Vishnu, V. Y. (2022) · touchREVIEWS in Neurology · doi:10.17925/usn.2022.18.1.49

Nanobiotechnology-Modified Cellular and Molecular Therapy as a Novel Approach for Autoimmune Diabetes Management

Lawand, P. V., & Desai, S. M. (2022) · Pharmaceutical Nanotechnology · doi:10.2174/2211738510666220802111315

Interaction Between Immune and Cancer Cells and Promising CAR T-cell Therapy

Rho, H., & Halasz, H. (2022) · Journal of Student Research · doi:10.47611/jsrhs.v11i3.2866

Oncolytic adenovirus Delta-24- RGD engineered to express 4-1BBL or OX40L as therapeutic approach for diffuse intrinsic pontine gliomas

Laspidea, V. (2022) · Deposito Adademico Digital Universidad De Navarra (University of Navarra) · doi:10.15581/10171/65228

Comparing how the microenvironments of the skin and lung shape T cell responses to vaccination

Palmer, O. R. (2020) · doi:10.26686/wgtn.22806971

Abatacept treatment in LRBA deficient patients results in an increase in circulating FoxP3 + Helios + natural TregPreprint

Donhauser, S., Salzmann‐Manrique, E., Lueck, L. M., Fekadu, J., Königs, C., Schubert, R., Kaffenberger, C., Moser, L. M., Bader, P., Huenecke, S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.10.579765

Effect of severity of injury on immune system and its role in patient outcome in patients with Blunt Trauma to the chestPreprint

Kabiraj, P., Mathur, P., Rajput, N., Priyadarshini, P., Kumar, A., Alam, J., Choudhary, N., Bagaria, D. K., Aggarwal, R., Soni, K. D., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4253254/v1

Role of regulatory T cells in the pathogenesis and therapeutics of neuromyelitis optica spectrum disorder

Redfern, J. S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13947-5.00002-6

Role of regulatory T cells in pathogenesis and therapeutics of celiac disease

Shah, F., & Dwivedi, M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13947-5.00011-7

THE ROLE AND FUNCTION OF REGULATORY T CELLS (TREGS) IN PREGNANCY AND PREECLAMPSIA: A NARRATIVE REVIEW

Hashemi, V., & Hosseini, A. (2024) · Studies in Medical Sciences · doi:10.61186/umj.35.3.218

Regulatory T cell infiltration precedes early events associated with persistent infectious bronchitis virus (IBV) infection in the cecal tonsils of chickens

Suhail, S. M., Isham, I. M., Farooq, M., Azhar, M., Ali, A., Mahmoud, M. E., Ghaffar, A., Herath-Mudiyanselage, H., Cork, S. C., Gupta, A. V., et al. (2025) · Virology · doi:10.1016/j.virol.2025.110691

Comparison of the Abilities of IL-10- and Retinoic Acid- Differentiated Dendritic Cells to Induce Allergen Tolerance in a Mouse Model of Asthma

Li, C. (2014) · University Library - University of Saskatchewan (University of Saskatchewan)

Lipid nanoparticle-mediated Cd14 siRNA delivery ameliorates the acute inflammatory response to intracortical microelectrode implantation

Graham, F., Hutchinson, D. W., Moon, T. J., Wang, J., Flores-Jimenez, H., Druschel, L. N., Ogunnaike, L., Gao, Y., Smith, T., DeTillio, S., et al. (2026) · Acta Biomaterialia · doi:10.1016/j.actbio.2026.01.055 · Cited by 1

De l’importance des médiateurs du stress dans le contrôle de l’immunité

Bacou, E. (2017) · theses.fr (ABES) · doi:10.70675/c3e20630z2e84z4f0ez9c4ez2ff5647f0f03

Impact de la delphinidine sur les fonctions de lymphocytes T chez les sujets sains et les patients atteints de syndrome métabolique

Dayoub, O. (2016) · theses.fr (ABES) · doi:10.70675/b096c0a2zef1bz46bfz9e9cz962e8f4cf345

Rôle du facteur de transcription Foxo3 dans la différenciation des LT CD4+ et la susceptibilité à l'auto-immunité

Stienne, C. (2015) · theses.fr (ABES) · doi:10.70675/2c3f3df6z7589z4d1aza311zce4830fc17fa

CD28 : nouvelles données sur un récepteur majeur de la costimulation lymphocytaire T

Morin, S. O. (2017) · theses.fr (ABES) · doi:10.70675/cb01635fz2f63z43e2zad0cz210485c4c5cf

A Study on the Role of the Intestinal MAdCAM-1/alpha4beta7 Axis in Tumor Immunosurveillance During PD-1 Blockade

Rauber, C. (2019) · theses.fr (ABES) · doi:10.70675/5fb4cecbz179az43d6z9448zfb2d158b7f02

Depression and the Immune Responses

Sunzeri, F. (2026) · Springer eBooks · doi:10.1007/978-3-032-14465-2_10

From Tregs to tissue remodelling: FOXP3 and IL-35 in the inflammatory landscape of nasal polyps

Gokulakannan, G., Jalil, N. A. C., Kadir, R., Ramli, R. R., Abdullah, B., Lambuk, F., & Shukri, N. M. (2026) · Inflammation Research · doi:10.1007/s00011-026-02271-0

Breast-specific regulatory T cell mediators

Modanwal, S., Mishra, A., Mishra, N., & Sethi, G. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-43846-2.00003-9

Bone-specific regulatory T cell mediators

Mishra, A. K., Singh, H., Agarwal, J., Pinki, K., Kumar, A., Mishra, A., & Khan, G. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-43846-2.00016-7

Brain-specific regulatory T cell mediators

Bharadwaj, A., Ashwani, Bhamboo, N., Vikash, & Gugulothu, D. B. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-43846-2.00008-8

Microfluidic Precision Engineered Artificial GARP Presenting Cells for Regulatory T-Cell Induction

Yi, H., Agrawal, S., Tam, G., Fong, N., Chen, J., Agrawal, A., & Lee, A. P. (2026) · Annals of Biomedical Engineering · doi:10.1007/s10439-026-04278-4

Sema3E ‐ plexinD1 Axis Is a Modulator of Foxp3 + Regulatory T‐Cells in House Dust Mite Model of Asthma

Matloubi, M., Onyilagha, C., Shan, L., Basu, S., Halayko, A. J., Almiski, M. S., & GOUNNI, A. S. (2026) · The FASEB Journal · doi:10.1096/fj.202502055rr

T cell exhaustion in parasitic infections

Gao, G., Wang, H., Mohamed, R., & Liang, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1910471

Loss of T cell-intrinsic Keap1 alleviates colitis by suppressing Th17 differentiation and enhancing regulatory T cell functions

Dasgupta, D., Tripathi, A., Griffard-Smith, R., Dahabieh, M. S., Saif, M. S. I., Roy, B. C., Burt, E., Ellis, A., Sheldon, R. D., Dhorajiya, P., et al. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104461

Role of LGALS9 and Human Milk Oligosaccharides in Modulating Immune Responses in Food Allergy: Insights from Network Pharmacology and Molecular Simulations

Chen, S., Ai, K., Liu, Y., Xiong, Z., Zhong, W., Yang, A., Wu, Z., Chen, H., & Li, X. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154764

Potencial profilático de estratégias vacinais no diabetes experimental

da Rosa, L. C. (2012) · Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences

Forward genetic analysis of natural T regulatory cell development

Salisbury, E. M. (2013) · Spiral (Imperial College London) · doi:10.25560/18844

The presence of CD25 on bovine WC1 plus gamma delta T cells is positively correlated with their production of IL-10 and TGF-beta, but not IFN-gamma

Maślanka, T., JAROSZEWSKI, J. J., Markiewicz, W., Ziółkowski, H., & Barski, D. (2012) · Polish Journal of Veterinary Sciences

The effects of environmental oxygen on CD4+ T lymphocyte activation and responses

Clay, E. (2015) · University of Birmingham Institutional Research Archive (University of Birmingham)

Mechanisms regulating the development and function of natural regulatory T cells

Gupta, S., Shang, W., & Sun, Z. (2008) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-008-0015-4 · Cited by 23

Regulatory T cells: a review.

Dasgupta, A., & Saxena, R. (2012) · PubMed · Cited by 41

Regulatory T Cells and Its Mechanism of Immunosuppression

Ai-ron, C. (2014) · Chinese Journal of Clinical Neurosciences · Cited by 2

Regulatory T Cells and Immune Tolerance

Sakaguchi, S., Yamaguchi, T., Nomura, T., & Ono, M. (2008) · Cell · doi:10.1016/j.cell.2008.05.009 · Cited by 5,485

Regulatory T cells: The suppressor arm of the immune system

Langier, S., Sade, K., & Kivity, S. (2010) · Autoimmunity Reviews · doi:10.1016/j.autrev.2010.08.013 · Cited by 43