The DOI matches its Crossref record; 183 of the 183 references it cites were found in a registry or an index.
AMP-activated protein kinase and its downstream transcriptional pathways
Open accessAbstract
The AMP-activated protein kinase (AMPK) is a key regulator of catabolic versus anabolic processes. Its properties as an energy sensor allow it to couple the energy status of the cell to the metabolic environment. These adaptations not only take place through the acute modulation of key metabolic enzymes via direct phosphorylation, but also through a slower transcriptional adaptative response. The question of how AMPK regulates the expression of a number of gene sets, such as those related to mitochondrial biogenesis, energy production and oxidative protection, is only beginning to be elucidated, and still many questions remain to be answered. In this review we will try to integrate our current knowledge on how AMPK regulates transcription in muscle and liver, which will serve as examples to illustrate the major advances in the field and the key challenges ahead.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Activation of AMPK increases mitochondrial chemical energy generation by increasing the AMP to ATP ratio236.”
From Mitochondrial and metabolic dysfunction in ageing and age-related diseases (2022) · cites this paper as [236]
In the citing paper
“This two-step activation of PGC-1α might be a conserved mechanism for AMPK to confer specificity among the various targets of SIRT1 (Canto & Auwerx, 2010).”
From Mitochondrial response to nutrient availability and its role in metabolic disease (2014) · cites this paper as Canto & Auwerx, 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels
Catterall, W. A., Chandy, K. G., Clapham, D. E., Gutman, G. A., Hofmann, F., Harmar, A. J., Abernethy, D. R., & Spedding, M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.4.5 · Cited by 7,126
Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action
Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13505 · Cited by 5,652
Resveratrol improves health and survival of mice on a high-calorie diet
Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290
Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139
Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057
Self-citationTSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Gwinn, D. M., Shackelford, D. B., Egan, D. F., Mihaylova, M. M., Mery, A., Vasquez, D. S., Turk, B. E., & Shaw, R. J. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.03.003 · Cited by 3,849
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L.-L., et al. (2003) · Nature · doi:10.1038/nature01960 · Cited by 3,796
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Imai, S.-I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000) · Nature · doi:10.1038/35001622 · Cited by 3,510
Cited by
Sorted by citations
Items 301–400 of 418
Central Apolipoprotein A-IV Stimulates Thermogenesis in Brown Adipose Tissue
Pence, S., LaRussa, Z., Shen, Z., Liu, M., Coschigano, K. T., Shi, H., & Lo, C. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031221 · Cited by 8
Zhang, G., Zhang, T., Jin, Y., Liu, J., Guo, Y., Fan, Y., El-Samahy, M. A., Meng, F., Wang, F., & Lei, Z. (2018) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2018.01.009 · Cited by 10
Screening of Therapeutic Targets for Canine Mast Cell Tumors from a Variety of Kinase Molecules
Takeuchi, Y., Fujino, Y., Watanabe, M., Nakagawa, T., Ohno, K., Sasaki, N., Sugano, S., & Tsujimoto, H. (2011) · Journal of Veterinary Medical Science · doi:10.1292/jvms.11-0093 · Cited by 7
Srivastava, A., Singh, S., Rajpurohit, C. S., Srivastava, P., Pandey, A., Kumar, D., Khanna, V. K., & Pant, A. B. (2018) · NeuroMolecular Medicine · doi:10.1007/s12017-018-8487-9 · Cited by 7
Li, X., Zhu, Q., Yang, Z., Zhu, M., Xie, Z., Fan, Y., & Zhao, T. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119626 · Cited by 6
Is the secret for a successful aging to keep track of cancer pathways?
Tramontano, D., & Amicis, F. D. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26825 · Cited by 6
Ruderman, N. B., & Shulman, G. I. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00043-3 · Cited by 7
Naderian, R., Pari, S. M., Hemmati, M. A., & Eslami, M. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01802-6 · Cited by 5
Kodi, T., Nandakumar, K., & Kishore, A. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05932-7 · Cited by 6
Ana, C. T. S., Ju, J., de Barros, F. A. R., & Kim, K. (2024) · Journal of Food Science · doi:10.1111/1750-3841.17224 · Cited by 5
Casillas-Ramírez, A., Maroto-Serrat, C., Sanus, F., Micó-Carnero, M., Rojano-Alfonso, C., Cabrer, M., & Peralta, C. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.10.016 · Cited by 5
Hirai, I., Ebara, M., Nakanishi, S., Yamamoto, C., Sasaki, T., Ikuta, K., & Yamamoto, Y. (2012) · Immunobiology · doi:10.1016/j.imbio.2012.06.008 · Cited by 5
Metformin and reprogramming into iPSCs
Serrano, M. (2012) · Cell Cycle · doi:10.4161/cc.11.6.19745 · Cited by 5
Park, S. H., Sung, Y.-Y., Jang, S., Nho, K. J., Choi, G., & Kim, H. K. (2016) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-016-1309-4 · Cited by 5
Hou, Y., Su, L. C., Zhao, Y., Liu, C., Yao, D., Zhang, M., Zhao, L., & Jin, Y. (2021) · Journal of Applied Animal Research · doi:10.1080/09712119.2021.1889563 · Cited by 5
Satô, A., Sato, S., Omori, G., & Koshinaka, K. (2022) · Nutrients · doi:10.3390/nu14030710 · Cited by 5
Dai, G., Li, M., He, X., & Quan, N. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.101910 · Cited by 5
Xu, A., Wang, L., Luo, M., Zhang, H., Ning, M., Pan, J., Duan, X., Wang, Y., & Liu, X. (2023) · Molecular Medicine Reports · doi:10.3892/mmr.2023.13141 · Cited by 5
Uchiumi, F., Larsen, S. H., & Tanum, S.-I. (2013) · InTech eBooks · doi:10.5772/53905 · Cited by 6
Yang, N., Chung, D., Liu, C., Liang, B., & Li, X.-M. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-261 · Cited by 5
Amaral, M. E. C., Ribeiro, R. A., Vanzela, E. C., & Barbosa‐Sampaio, H. C. (2016) · International Journal of Experimental Pathology · doi:10.1111/iep.12165 · Cited by 5
AMPK-mediatedhy Poglycemic Effect of Banana Stem Juice on Type 2 Diabetes
Dong, N. T. K., & Huong, P. T. (2020) · Biosciences Biotechnology Research Asia · doi:10.13005/bbra/2812 · Cited by 5
Increased BAT Thermogenesis in Male Mouse Apolipoprotein A4 Transgenic Mice
LaRussa, Z., Kuo, H.-C. N., West, K., Shen, Z., Wisniewski, K., Tso, P., Coschigano, K. T., & Lo, C. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044231 · Cited by 5
Resveratrol: A Sirtuin Activator and The Fountain of Youth
Meiliana, A., Dewi, N. M., & Wijaya, A. (2015) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v7i1.16 · Cited by 4
Austin, J. A., Jenkins, R. E., Austin, G. M., Glenn, M. A., Dunn, K. M., Scott, L. J., Lucas, C., & Clark, R. E. (2019) · Biochemical Journal · doi:10.1042/bcj20190121 · Cited by 5
Gorica, E., Piragine, E., Mengozzi, A., Cappelli, F., Duranti, E., Masi, S., Virdis, A., Testai, L., Pagnotta, E., Righetti, L., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118238 · Cited by 4
Sun, Y., Li, F., Hua, W., Che, Z., Tian, M., Lu, Y.-Y., & Huang, Q. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.140485 · Cited by 6
Expression of the Forkhead box transcription factor Foxo3a in human periapical granulomas
Ishii, K., Hatori, K., Takeichi, O., Makino, K., Himi, K., Komiya, H., & Ogiso, B. (2018) · Journal of Oral Science · doi:10.2334/josnusd.17-0439 · Cited by 4
Agaty, S. M. E. (2018) · General Physiology and Biophysics · doi:10.4149/gpb_2018026 · Cited by 4
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells
Lee, Y., Chiou, J., Wang, L., & Chang, L. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115017 · Cited by 4
1,25-(OH) 2 D 3 ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway
Tian, S., Yang, X., Wang, J., Luo, J., & Guo, H. (2021) · Journal of International Medical Research · doi:10.1177/0300060520981360 · Cited by 4
Cytosolic DNA and intracellular Ca2+: Maintaining genome stability during replication stress
Li, S., Lu, H.-T., & You, Z. (2025) · DNA repair · doi:10.1016/j.dnarep.2025.103877 · Cited by 3
Odriozola-Martínez, A., González, A., Odriozola, I., Corbi, F., & Álvarez‐Herms, J. (2025) · Nutrients · doi:10.3390/nu18010059 · Cited by 3
A nutrient-responsive AMPK/TBK1 circuit restricts adipocyte catabolism
Wisessaowapak, C., Skorobogatko, Y. V., Kim, H., Xue, F., Son, S., Fu, H., Zhang, S., Lertvilai, P., Chang, L., Hoang, A., et al. (2026) · JCI Insight · doi:10.1172/jci.insight.200168 · Cited by 3
Feldman, F., Koudoufio, M., Sané, A. T., Marcil, V., Sauvé, M. F., Butcher, J., Patey, N., Martel, C., Spahis, S., Duan, H., et al. (2025) · Antioxidants · doi:10.3390/antiox14030268 · Cited by 5
Novel function of TREK-1 in regulating adipocyte differentiation and lipid accumulation
Kim, A., Jung, S., Kim, Y., Jung, J., Lee, S., Lee, H., Kim, M. J., Park, J., Hwang, E. M., & Lee, J. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07478-3 · Cited by 3
Park, K., Jung, S., Li, C., Ha, J., & Jeong, Y. (2025) · Nutrients · doi:10.3390/nu17121990 · Cited by 4
Behera, S., & Ghosh‐Roy, A. (2026) · Journal of Neuroscience · doi:10.1523/jneurosci.0124-25.2026 · Cited by 3
When histones are under glucose starvation
Lee, J., Oh, S., Abmayr, S. M., & Workman, J. L. (2020) · Journal of Biosciences · doi:10.1007/s12038-019-9971-6 · Cited by 3
Analysis of miRNA expression profile in lung tissues of an intermittent hypoxia rat model
Liu, Z., Ai, L., Li, R., Yang, Y., Chen, K., He, C., & Li, Y. (2021) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2021.103741 · Cited by 3
Wang, D., Wang, J., Yin, Z., Gong, K. Q., Zhang, S., Zha, Z., & Duan, Y. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s485084 · Cited by 3
Liu, X., Chen, J., Li, J., Zeng, Z., Jiang, X., Gao, Y., Huang, Z., Wu, Q., Gong, Y. Q., & Xie, C. (2021) · Gene · doi:10.1016/j.gene.2021.145900 · Cited by 3
Ali, M., Bakr, M. H., Abdelzaher, L. A., Sayed, S. A., Mali, V., Desai, A. A., & Radwan, E. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155398 · Cited by 3
Starvation and fasting: Biochemical Aspects
Haller, W., & Bines, J. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-375083-9.00254-3 · Cited by 3
Starvation and fasting: Biochemical aspects
McGrath, K. H., Haller, W., & Bines, J. E. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821848-8.00068-8 · Cited by 3
Sha, P., Feng, X., Wang, Y., Meng, J., Deng, L., Ma, Z., Li, D., Wang, J., Zhou, Z., Zhu, J., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.138268 · Cited by 2
Sun, R., Li, W., Liao, M., Yu, Y., Mou, Y., Ji, J., Chen, F., Hu, X., & Ma, L. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107348 · Cited by 3
Shin, S.-B., Kim, Y., & Park, H. (2025) · Genes & Nutrition · doi:10.1186/s12263-025-00788-3 · Cited by 2
El‐Moaty, H. I. A., Saber, S., Hamad, R. S., Elmorsy, E. A., Farrag, A. A. M., Cavalu, S. D., Eissa, H., El-kott, A. F., Negm, S., AlShehri, M. A., et al. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103375 · Cited by 2
Zheng, J., Zhao, J., Li, M., Cheng, Y., Fang, X., Zhao, L., & Zhao, Y. (2026) · Journal of Animal Science · doi:10.1093/jas/skag152 · Cited by 2
Heat Therapy Can Improve Hepatic Mitochondrial Function and Glucose Control
Johnson, C. N., Jensen, R. S., Schulze, A. T. V., & Geiger, P. C. (2022) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000296 · Cited by 2
Chen, W., Gao, S. Z., Zhao, N., Han, L., & Sun, P. (2024) · Aquaculture Reports · doi:10.1016/j.aqrep.2024.102316 · Cited by 2
Fan, J. (2024) · American Journal of Translational Research · doi:10.62347/jbre5043 · Cited by 2
Duo, R., Wang, Y., Ma, Q., Wang, X., Zhang, Y., & Shen, H. (2025) · Clinical Rheumatology · doi:10.1007/s10067-025-07406-y · Cited by 2
Al-Suhaimi, E. A. (2014) · Anales de la Real Academia Nacional de Farmacia · Cited by 2
A Mimic of the Tumor Microenvironment on GPR30 Gene Expression in Breast Cancer
Rasoulpoor, S., Asgharzadeh, M. R., & Shabani, S. (2022) · Multidisciplinary Cancer Investigation · doi:10.30699/mci.6.2.584-1 · Cited by 2
To eat or not to eat – Anti‐ageing effects of energy restriction
Neves, D., Martins, M. J., Passos, E., & Tomada, I. (2015) · Wiley eBooks · doi:10.1002/9781118823408.ch2 · Cited by 2
Contributions of AMP kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases
Kodiha, M., Mahboubi, H., & Stochaj, U. (2013) · Wiley eBooks · doi:10.1002/9781118395318.ch22 · Cited by 2
Tough, R. H., & McLaren, P. J. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2025.1551171 · Cited by 1
Hesperetin Induces Apoptosis of Human Gastric Adenocarcinoma Cells
Yang, J. Y., Kim, H. W., Woo, H. J., Kim, J. Y., Park, M., & Kim, S. (2025) · Journal of Experimental & Biomedical Sciences/Biomedical Science Letters · doi:10.15616/bsl.2025.31.2.137 · Cited by 1
DDR2 ameliorates nonalcoholic hepatic steatosis by activating the AMPK/ACC pathway
Guo, M., Lin, L., Wang, Y., Gao, J., Xiang, W., Hua, H., Wang, D., Huang, C., Wang, X., Zou, B., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-42992-0 · Cited by 1
Flück, M., Gasser, B. A., & Giraud, M.-N. (2026) · The FASEB Journal · doi:10.1096/fj.202504082r · Cited by 1
Compounds in Vegetables Including Okra and Fenugreek of Potential Value in the Treatment of Diabetes
Lea, M. A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-397153-1.00028-7 · Cited by 1
SIRT7: from a Metabolic Regulator to a Disease Marker
Lin, Z. (2015) · International Journal of Cancer Studies & Research · doi:10.19070/2167-9118-150009 · Cited by 1
Vaiserman, A. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12295-4 · Cited by 1
Ruan, Z., Ge, W., He, Z., Pan, C., Luo, X., Lv, M., Bi, X., & Ma, H. (2014) · Turkish Journal of Fisheries and Aquatic Sciences · doi:10.4194/trjfas23871 · Cited by 1
Investigating the role and regulation of the AMPK-related kinase NUAK1
Bull, D. (2013) · doi:10.25560/23995 · Cited by 1
SHP gains citizenship of the AMPK kingdom
Chung, H. (2011) · Cellular and Molecular Immunology · doi:10.1038/cmi.2011.39 · Cited by 1
Mehanna, R. A., Hassaan, P. S., Nomeir, H. M., & Dwedar, F. (2018) · Bulletin of Egyptian Society for Physiological Sciences · doi:10.21608/besps.2018.8159 · Cited by 1
Resveratrol Inhibitory Effects Against a Malignant Tumor: A Molecular Insight
Wcisło, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813008-7.00018-7 · Cited by 1
Cantó, C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-811752-1.00017-1 · Cited by 1
Self-citationLKB1/AMPK pathway in the control of hepatic energy metabolism
Viollet, B., & Foretz, M. (2015) · Wiley eBooks · doi:10.1002/9781118663387.ch23 · Cited by 1
Athippozhy, A. (2011) · UKnowledge (University of Kentucky)
Determining the Role of Autophagy in HER2/neu-Induced Mammary Tumor Dormancy and Recurrence
Dwyer, S. (2013) · Scholarly Commons (University of Pennsylvania)
Adapt, Survive or Die - Metabolic Imbalances and the Enteric Nervous System
Voss, U. (2013) · Lund University Publications (Lund University)
Nissinen, T. A. (2014) · Jyväskylä University Digital Archive (University of Jyväskylä)
Eastern boundary currents off North-West Africa
Pelegrí, J. L., & Peña‐Izquierdo, J. (2015) · AquaDocs (United Nations Educational, Scientific and Cultural Organization) · doi:10.13039/501100003329 · Cited by 21
Resveratrol as a Novel Therapeutic Agent for Treating Duchenne Muscular Dystrophy
Burt, M. (2013) · uO Research (University of Ottawa) · doi:10.20381/ruor-3321
Autophagy in Metabolism, Cell Death, and Leukemogenesis
Altman, B. J. (2011) · DukeSpace (Duke University)
Batatinha, H. (2015) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2015.tde-08122015-185802
Kinases and Mitochondrial Cycling
Carreras, M. C., & Poderoso, J. J. (2012) · Oxidative stress and disease · doi:10.1201/b12308-13
Role of Autophagy Activation in Alleviating Alcohol Neurotoxicity
Luo, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00021-4
The Neurodegenerative Drosophila Melanogaster Ampk Mutant Loechrig
Cook, M. (2012) · Online Publication Service of Würzburg University (Würzburg University)
The role of folate in non-alcoholic fatty liver disease
Sid, V. (2019) · Mspace (University of Manitoba)
Hegab, M. (2019) · The Medical Journal of Cairo University/The Medical Journal of Cairo University · doi:10.21608/mjcu.2019.69916
Heat Shock Protein 72 Regulation of Metabolism
Archer, A. E. (2018) · KU ScholarWorks (The University of Kansas)
Munansangu, B. S. M. (2018) · Boloka Institutional Repository (North-west University)
The Effects of Chromium on Skeletal Muscle Membrane/Cytoskeletal Parameters and Insulin Sensitivity
Hoffman, N. J. (2012) · IUScholarWorks (Indiana University) · doi:10.7912/c2/1996
汤, 冉. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.133489
Zhu, Y., Deng, H., Liu, J., Li, X., Huang, X. H., Che, Z., Bai, W., & Jiao, R. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115639
The Impact of Gut Microbial Metabolomics on Type 2 Diabetes Development in People Living with HIV
Rodríguez, D., Anaya-Ambriz, E. J., Méndez-Ríos, P. C., Andrade-Villanueva, J. F., González-Hernández, L. A., Holguín-Aguirre, T. E., Martínez-Ayala, P., Ruíz-Herrera, V. V., Álvarez-Zavala, M., & Sánchez-Reyes, K. (2025) · Metabolites · doi:10.3390/metabo15090627
PRKAG1 mediates the anti-Japanese encephalitis virus effect of Nitazoxanide through autophagy
Ma, H., Wang, X., Wang, C., Ye, W., Zhou, W. H., Zou, F., & Zhang, K. (2025) · Veterinary Microbiology · doi:10.1016/j.vetmic.2025.110740
Metadata
- Authors
- Cantó, C., & Auwerx, J.
- Affiliations
- École Polytechnique Fédérale de Lausanne (CH)
- Corresponding author
- Auwerx, Johan
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2010-07-17
- Volume
- 67
- Issue
- 20
- Pages
- 3407-3423
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- PMC
- PMC3622821
- OpenAlex
- W2067872036
- Cited by
- 421
- References
- 183
- Citations by year
- 2026: 17 · 2025: 28 · 2024: 19 · 2023: 23 · 2022: 20 · 2021: 24 · 2020: 25 · 2019: 23 · 2018: 28 · 2017: 32 · 2016: 20 · 2015: 27 · 2014: 25 · 2013: 30 · 2012: 33
- FWCI
- 3.08
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cellular and Molecular Life Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- reroDoc Digital Library (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (DK-59820, P01DK059820)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Keywords
- AMPK, transcriptional regulation, energy sensing, mitochondrial biogenesis, muscle, liver, metabolic adaptation, gene expression regulation
- MeSH terms
- Animals, Humans, Models, Biological, Transcription, Genetic, Signal Transduction, AMP-Activated Protein Kinases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
