Cantó, Carles

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature

Metabolism, Diabetes, and CancerSirtuins and Resveratrol in Medicine

Cited by 3,300

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Cantó, C., Menzies, K. J., & Auwerx, J. (2015) · Cell Metabolism

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 1,648

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Cantó, C., & Auwerx, J. (2009) · Current Opinion in Lipidology

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,624

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Cantó, C., Houtkooper, R. H., Pirinen, E., Youn, D. Y., Oosterveer, M. H., Cen, Y., Fernandez-Marcos, P. J., Yamamoto, H., Andreux, P. A., Cettour-Rose, P., et al. (2012) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 1,238

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Mouchiroud, L., Houtkooper, R. H., Moullan, N., Katsyuba, E., Ryu, D., Cantó, C., Mottis, A., Jo, Y.-S., Viswanathan, M., Schoonjans, K., et al. (2013) · Cell

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 1,210

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

Cantó, C., Jiang, L. Q., Deshmukh, A. S., Mataki, C., Coste, A., Lagouge, M., Zierath, J. R., & Auwerx, J. (2010) · Cell Metabolism

Metabolism, Diabetes, and CancerSirtuins and Resveratrol in Medicine

Cited by 921

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

Bai, P., Cantó, C., Oudart, H., Brunyánszki, A., Cen, Y., Thomas, C., Yamamoto, H., Huber, A., Kiss, B., Houtkooper, R. H., et al. (2011) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 837

The metabolic footprint of aging in mice

Houtkooper, R. H., Argmann, C., Houten, S. M., Cantó, C., Jeninga, E. H., Andreux, P. A., Thomas, C., Doenlen, R., Schoonjans, K., & Auwerx, J. (2011) · Scientific Reports

Genetics, Aging, and Longevity in Model OrganismsMetabolomics and Mass Spectrometry Studies

Cited by 528

The molecular targets of resveratrol

Kulkarni, S. S., & Cantó, C. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer

Cited by 477

Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?

Cantó, C., & Auwerx, J. (2012) · Pharmacological Reviews

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 433

AMP-activated protein kinase and its downstream transcriptional pathways

Cantó, C., & Auwerx, J. (2010) · Cellular and Molecular Life Sciences

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 421

Caloric restriction, SIRT1 and longevity

Cantó, C., & Auwerx, J. (2009) · Trends in Endocrinology & Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 395

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Ratajczak, J., Joffraud, M., Trammell, S. A. J., Ras, R., Canela, N., Boutant, M., Kulkarni, S. S., Rodrigues, M., Redpath, P., Migaud, M. E., et al. (2016) · Nature Communications

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 378

The Role of PARP-1 and PARP-2 Enzymes in Metabolic Regulation and Disease

Bai, P., & Cantó, C. (2012) · Cell Metabolism

PARP inhibition in cancer therapySirtuins and Resveratrol in Medicine

Cited by 312

Mitochondrial function in the brain links anxiety with social subordination

Hollis, F., van der Kooij, M. A., Zanoletti, O., Lozano, L., Cantó, C., & Sandi, C. (2015) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorMitochondrial Function and Pathology

Cited by 288

Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle

Greggio, C., Jha, P., Kulkarni, S. S., Lagarrigue, S., Broskey, N. T., Boutant, M., Wang, X., Conde Alonso, S., Ofori, E., Auwerx, J., et al. (2017) · Cell Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 286

Calorie Restriction: Is AMPK a Key Sensor and Effector

Cantó, C., & Auwerx, J. (2011) · Physiology

Metabolism, Diabetes, and CancerGenetics, Aging, and Longevity in Model Organisms

Cited by 282

NAD + repletion improves muscle function in muscular dystrophy and counters global PARylation

Ryu, D., Zhang, H., Ropelle, E. R., Sorrentino, V., Mázala, D. A. G., Mouchiroud, L., Marshall, P. L., Campbell, M. D., Ali, A. S., Knowels, G. M., et al. (2016) · Science Translational Medicine

Sirtuins and Resveratrol in MedicineMuscle Physiology and Disorders

Cited by 256

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

Pirinen, E., Cantó, C., Jo, Y. S., Morato, L., Zhang, H., Menzies, K. J., Williams, E. G., Mouchiroud, L., Moullan, N., Hagberg, C., et al. (2014) · Cell Metabolism

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 254

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

Cantó, C., Sauve, A. A., & Bai, P. (2013) · Molecular Aspects of Medicine

Sirtuins and Resveratrol in MedicinePARP inhibition in cancer therapy

Cited by 246

Mitochondrial response to nutrient availability and its role in metabolic disease

Gao, A. W., Cantó, C., & Houtkooper, R. H. (2014) · EMBO Molecular Medicine

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 148

Circadian Rhythms and Mitochondria: Connecting the Dots

Sardon Puig, L., Valera-Alberni, M., Cantó, C., & Pillon, N. J. (2018) · Frontiers in Genetics

Circadian rhythm and melatoninMitochondrial Function and Pathology

Cited by 113

Distinct patterns of skeletal muscle mitochondria fusion, fission and mitophagy upon duration of exercise training

Arribat, Y., Broskey, N. T., Greggio, C., Boutant, M., Conde Alonso, S., Kulkarni, S. S., Lagarrigue, S., Carnero, E. A., Besson, C., Cantó, C., et al. (2019) · Acta Physiologica

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 112