The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
The myofibroblast, a key cell in normal and pathological tissue repair
Open accessAbstract
Myofibroblasts are characterized by their expression of α-smooth muscle actin, their enhanced contractility when compared to normal fibroblasts and their increased synthetic activity of extracellular matrix proteins. Myofibroblasts play an important role in normal tissue repair processes, particularly in the skin where they were first described. During normal tissue repair, they appear transiently and are then lost via apoptosis. However, the chronic presence and continued activity of myofibroblasts characterize many fibrotic pathologies, in the skin and internal organs including the liver, kidney and lung. More recently, it has become clear that myofibroblasts also play a role in many types of cancer as stromal or cancer-associated myofibroblast. The fact that myofibroblasts are now known to be key players in many pathologies makes understanding their functions, origin and the regulation of their differentiation important to enable them to be regulated in normal physiology and targeted in fibrosis, scarring and cancer.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Furthermore, during tissue repair, growth factors are induced by tissue injury and inflammation including CCN2/CTGF and CCN1/CYR61 that have respectively a stimulatory and antagonist effect on myofibroblasts proliferation and differentiation and on the resolution phase of the inflammatory state [24,25].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
Thomas, A. C., & Campbell, J. H. (2000) · Cited by 2,800
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., & Janmey, P. A. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20041 · Cited by 2,325
TGF-β signaling and the fibrotic response
Leask, A., & Abraham, D. J. (2004) · The FASEB Journal · doi:10.1096/fj.03-1273rev · Cited by 2,319
Desmoulière, A., Geinoz, A., Gabbiani, F., & Gabbiani, G. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.1.103 · Cited by 2,269
Self-citationPericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226
The extracellular matrix modulates the hallmarks of cancer
Pickup, M. W., Mouw, J. K., & Weaver, V. M. (2014) · EMBO Reports · doi:10.15252/embr.201439246 · Cited by 2,098
Yu, Q., & Stamenkovic, I. (2000) · PubMed · Cited by 1,952
Evidence that fibroblasts derive from epithelium during tissue fibrosis
Iwano, M., Plieth, D., Danoff, T. M., Xue, C., Okada, H., & Neilson, E. G. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15518 · Cited by 1,809
Yu, Q., & Stamenkovic, I. (2000) · Genes & Development · doi:10.1101/gad.14.2.163 · Cited by 1,754
Cited by
Sorted by citations
Cancer-associated fibroblasts in the single-cell era
Lavie, D., Ben‐Shmuel, A., Erez, N., & Scherz‐Shouval, R. (2022) · Nature Cancer · doi:10.1038/s43018-022-00411-z · Cited by 656
The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling
Shinde, A. V., Humeres, C. D., & Frangogiannis, N. G. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.11.006 · Cited by 602
Ford, K., Hanley, C. J., Mellone, M., Szyndralewiez, C., Heitz, F., Wiesel, P., Wood, O., Machado, M., Lopez, M.-A., Ganesan, A.-P., et al. (2020) · Cancer Research · doi:10.1158/0008-5472.can-19-3158 · Cited by 411
Marconi, G. D., Fonticoli, L., Rajan, T. S., Pierdomenico, S. D., Trubiani, O., Pizzicannella, J., & Diomede, F. (2021) · Cells · doi:10.3390/cells10071587 · Cited by 449
Skeletal muscle fibrosis: an overview
Mahdy, M. A. A. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2955-2 · Cited by 320
Jun, J.-I., & Lau, L. F. (2018) · Journal of Clinical Investigation · doi:10.1172/jci93563 · Cited by 358
D’Urso, M., & Kurniawan, N. A. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.609653 · Cited by 294
Muscle injuries and strategies for improving their repair
Laumonier, T., & Ménétrey, J. (2016) · Journal of Experimental Orthopaedics · doi:10.1186/s40634-016-0051-7 · Cited by 297
Samitas, Κ., Carter, A., Kariyawasam, H. H., & Xanthou, G. (2017) · Allergy · doi:10.1111/all.13373 · Cited by 271
The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets
Nguyen, J. K., Austin, E., Huang, A., Mamalis, A., & Jagdeo, J. R. (2019) · Archives of Dermatological Research · doi:10.1007/s00403-019-01972-3 · Cited by 243
Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy
Malecová, B., Gatto, S., Etxaniz, U., Passafaro, M., Cortez, A., Nicoletti, C., Giordani, L., Torcinaro, A., Bardi, M. D., Bicciato, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06068-6 · Cited by 221
Origin and Consequences of Necroinflammation
Sarhan, M., Land, W. G., Tonnus, W., Hugo, C., & Linkermann, A. (2018) · Physiological Reviews · doi:10.1152/physrev.00041.2016 · Cited by 217
Bonté, F., Girard, D., Archambault, J.-C., & Desmoulière, A. (2019) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-3681-2_10 · Cited by 225
Self-citationCurrent and upcoming therapies to modulate skin scarring and fibrosis
Coentro, J. Q., Pugliese, E., Hanley, G., Raghunath, M., & Zeugolis, D. I. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.08.009 · Cited by 207
Drug targeting to myofibroblasts: Implications for fibrosis and cancer
Yazdani, S., Bansal, R., & Prakash, J. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.07.010 · Cited by 191
He, J., Fang, B., Shan, S., Xie, Y., Wang, C., Zhang, Y., Zhang, X., & Li, Q. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03481-6 · Cited by 178
Fibroblast-to-myofibroblast transition in bronchial asthma
Michalik, M., Wójcik‐Pszczoła, K., Paw, M., Wnuk, D., Koczurkiewicz, P., Sanak, M., Pękala, E., & Madeja, Z. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2899-4 · Cited by 160
Tenbrock, L., Wolf, J., Boneva, S., Schlecht, A., Agostini, H. T., Wieghofer, P., Schlunck, G., & Lange, C. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03514-8 · Cited by 161
Ţuţuianu, R., Rosca, A., Iacomi, D. M., Simionescu, M., & Titorencu, I. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126239 · Cited by 121
Hyaluronic Acid and Skin: Its Role in Aging and Wound-Healing Processes
Chylińska, N., & Maciejczyk, M. (2025) · Gels · doi:10.3390/gels11040281 · Cited by 150
3D in vitro M2 macrophage model to mimic modulation of tissue repair
Sapudom, J., Karaman, S., Mohamed, W. K. E. A., Garcia‐Sabaté, A., Quartey, B. C., & Teo, J. C. M. (2021) · npj Regenerative Medicine · doi:10.1038/s41536-021-00193-5 · Cited by 120
Role of the Hippo Pathway in Fibrosis and Cancer
Kim, C.-L., Choi, S.-H., & Mo, J. (2019) · Cells · doi:10.3390/cells8050468 · Cited by 114
Wermuth, P. J., Li, Z., Mendoza, F. A., & Jiménez, S. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161988 · Cited by 110
Guerra, L., Odorisio, T., Zambruno, G., & Castiglia, D. (2017) · Matrix Biology · doi:10.1016/j.matbio.2017.01.002 · Cited by 110
Advances in 3D skin bioprinting for wound healing and disease modeling
Zhang, M., Zhang, C., Li, Z., Fu, X., & Huang, S. (2022) · Regenerative Biomaterials · doi:10.1093/rb/rbac105 · Cited by 118
Silica particles disorganize the polarization of pulmonary macrophages in mice
Zhao, Y., Hao, C., Bao, L., Wang, D., Li, Y., Qu, Y., Ding, M., Zhao, A., & Yao, W. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.110364 · Cited by 104
Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300
Williams, L. M., McCann, F. E., Cabrita, M., Layton, T., Cribbs, A. P., Knezevic, B., Fang, H., Knight, J. C., Zhang, M., Fischer, R., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2004281117 · Cited by 88
McAndrews, K. M., Miyake, T., Ehsanipour, E. A., Kelly, P. J., Becker, L. M., McGrail, D. J., Sugimoto, H., LeBleu, V. S., Ge, Y., & Kalluri, R. (2022) · The EMBO Journal · doi:10.15252/embj.2021109470 · Cited by 91
Schulz, J.-N., Plomann, M., Sengle, G., Gullberg, D., Krieg, T. M., & Eckes, B. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.01.025 · Cited by 88
Advances in biomaterials for skeletal muscle engineering and obstacles still to overcome
Smoak, M. M., & Mikos, A. G. (2020) · Materials Today Bio · doi:10.1016/j.mtbio.2020.100069 · Cited by 81
Mechanisms and Future of Non-Small Cell Lung Cancer Metastasis
Zhu, T., Bao, X., Chen, M., Lin, R., Zhuyan, J., Zhen, T., Xing, K., Zhou, W. J., & Zhu, S. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.585284 · Cited by 85
Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
Feng, Y., Wu, J., Sun, Z., Liu, S., Zou, M., Yuan, Z., Yu, S., Lv, G., & Yuan, F. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102715 · Cited by 81
The Mighty Fibroblast and Its Utility in Scleroderma Research
Garrett, S. M., Frost, D. B., & Feghali‐Bostwick, C. A. (2017) · Journal of Scleroderma and Related Disorders · doi:10.5301/jsrd.5000240 · Cited by 78
Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells.
Baassiri, M. G. E., Dosh, L., Haidar, H., Gerges, A., Baassiri, S., Leone, A., Rappa, F., & Jurjus, A. (2022) · Burns · doi:10.1016/j.burns.2022.11.001 · Cited by 69
Collagen Fibril Density Modulates Macrophage Activation and Cellular Functions during Tissue Repair
Sapudom, J., Mohamed, W. K. E. A., Garcia‐Sabaté, A., Alatoom, A., Karaman, S., Mahtani, N., & Teo, J. C. M. (2020) · Bioengineering · doi:10.3390/bioengineering7020033 · Cited by 72
Girard, D., Laverdet, B., Buhé, V., Trouillas, M., Ghazi, K., Alexaline, M. M., Egles, C., Misery, L., Coulomb, B., Lataillade, J., et al. (2016) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2016.0195 · Cited by 73
Self-citationVu, T. N., Chen, X., Foda, H. D., Smaldone, G. C., & Hasaneen, N. A. (2019) · Respiratory Research · doi:10.1186/s12931-019-1171-2 · Cited by 73
Ibañez, R. I. R., do Amaral, R. J. F. C., Reis, R. L., Marques, A. P., Murphy, C. M., & O’Brien, F. J. (2021) · Polymers · doi:10.3390/polym13152510 · Cited by 71
Fibroblast fate regulation by time dependent TGF-β1 and IL-10 stimulation in biomimetic 3D matrices
Sapudom, J., Wu, X., Chkolnikov, M., Ansorge, M., Anderegg, U., & Pompe, W. (2017) · Biomaterials Science · doi:10.1039/c7bm00286f · Cited by 69
Chan, J. S. K., Sng, M. K., Teo, Z. Q., Chong, H. C., Twang, J. S., & Tan, N. S. (2017) · Oncogene · doi:10.1038/onc.2017.319 · Cited by 67
Role of NGF and its receptors in wound healing (Review)
Liu, Z., Wu, H., & Huang, S. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10031 · Cited by 70
Wnuk, D., Paw, M., Ryczek, K., Bochenek, G., Sładek, K., Madeja, Z., & Michalik, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-73473-7 · Cited by 64
Stem cells, niches and scaffolds: Applications to burns and wound care
Watt, S. M., & Pleat, J. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.10.012 · Cited by 63
Otsuka, M., Shiratori, M., Chiba, H., Kuronuma, K., Sato, Y., Niitsu, Y., & Takahashi, H. (2017) · Experimental Lung Research · doi:10.1080/01902148.2017.1354946 · Cited by 63
Li, N., Wang, Z., Gao, F., Lei, Y., & Li, Z. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15221 · Cited by 59
GLP-1 receptor agonist ameliorates experimental lung fibrosis
Fandiño, J., Toba, L., González-Matías, L. C., Diz-Chaves, Y., & Mallo, F. (2020) · Scientific Reports · doi:10.1038/s41598-020-74912-1 · Cited by 63
Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway
Li, X., Xiao, T., Yang, J., Qin, Y., Gao, J., Liu, H., & Zhou, H. (2018) · Respiratory Research · doi:10.1186/s12931-018-0806-z · Cited by 61
Laloze, J., Fiévet, L., & Desmoulière, A. (2020) · Advances in Wound Care · doi:10.1089/wound.2020.1175 · Cited by 58
Self-citationCheng, W., Pan, Y., Zhang, Y., Dai, Y., Jiang, L., Shi, L., Yang, W., Xu, S., Zhang, Y., Xu, W., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-02956-2 · Cited by 57
Zhang, J., Qu, C., Li, T., Cui, W., Wang, X., & Du, J. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.008795 · Cited by 58
Grosche, J., Meißner, J., & Eble, J. A. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.03.005 · Cited by 53
Ijaz, T., Jamaluddin, M., Zhao, Y., Zhang, Y., Jay, J. W., Finnerty, C. C., Herndon, D. N., Tilton, R. G., & Brasier, A. R. (2017) · Cell Death and Disease · doi:10.1038/cddis.2016.434 · Cited by 54
Hamanaka, R. B., & Mutlu, G. M. (2021) · Amino Acids · doi:10.1007/s00726-021-02996-8 · Cited by 54
Marconi, G. D., Fonticoli, L., Rajan, T. S., Lanuti, P., Rocca, Y. D., Pierdomenico, S. D., Trubiani, O., Pizzicannella, J., & Diomede, F. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.676512 · Cited by 53
Grove, L. M., Mohan, M. L., Abraham, S., Scheraga, R. G., Southern, B. D., Crish, J. F., Prasad, S. V. N., & Olman, M. A. (2019) · Science Signaling · doi:10.1126/scisignal.aau1533 · Cited by 51
The current landscape of antifibrotic therapy across different organs: A systematic approach
Fuster‐Martínez, I., & Calatayud, S. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107245 · Cited by 60
Nanchahal, J., Ball, C., Davidson, D., Williams, L. M., Sones, W. R., McCann, F. E., Cabrita, M., Swettenham, J. B., Cahoon, N. J., Copsey, B. J., et al. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.06.022 · Cited by 52
Leask, A. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.10.016 · Cited by 52
Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Antifibrotic Prostaglandins
Lacy, S., Woeller, C. F., Thatcher, T., Pollock, S. J., Small, E., Sime, P., & Phipps, R. (2019) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2017-0248oc · Cited by 47
Zoppi, N., Chiarelli, N., Binetti, S., Ritelli, M., & Colombi, M. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.01.005 · Cited by 49
Huang, X., Gu, S., Liu, C., Zhang, L., Zhang, Z., Zhao, Y., Khoong, Y., Li, H., Gao, Y., Liu, Y., et al. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.07.181 · Cited by 49
Bersini, S., Gilardi, M., Mora, M., Krol, S., Arrigoni, C., Candrian, C., Zanotti, S., & Moretti, M. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.02.009 · Cited by 56
Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy
Zheng, W., Qian, Y., Chen, S., Ruan, H., & Fan, C. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00402 · Cited by 48
Tan, S., Han, J., Yuan, X., Song, Z., Gao, L., Gao, J., & Wang, L. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.111701 · Cited by 50
Salminen, A., Kaarniranta, K., & Kauppinen, A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102296 · Cited by 50
Granato, G., Ruocco, M. R., Iaccarino, A., Masone, S., Calı̀, G., Avagliano, A., Russo, V., Bellevicine, C., Spigna, G. D., Fiume, G., et al. (2017) · Cell Death Discovery · doi:10.1038/cddiscovery.2017.38 · Cited by 45
Paish, H. L., Kalson, N. S., Smith, G. R., Pons, A. D. C., Baldock, T., Smith, N., Swist-Szulik, K., Weir, D. J., Bardgett, M., Deehan, D. J., et al. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.11.007 · Cited by 45
Sapudom, J., Müller, C. D., Nguyen, K.-T., Martin, S., Anderegg, U., & Pompe, W. (2020) · Gels · doi:10.3390/gels6040033 · Cited by 49
An Emerging Frontier in Intercellular Communication: Extracellular Vesicles in Regeneration
Avalos, P. N., & Forsthoefel, D. J. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.849905 · Cited by 51
Chen, Q., Li, S., Li, K., Zhao, W., & Zhao, C. (2024) · Advanced Science · doi:10.1002/advs.202306018 · Cited by 42
Stroma in normal and cancer wound healing
Huet, E., Jaroz, C., Nguyen, H. Q., Belkacemi, Y., de la Taille, A., Stavrinides, V., & Whitaker, H. (2019) · The FEBS Journal · doi:10.1111/febs.14842 · Cited by 42
Liu, X., Wang, J., Dou, P., Zhang, X., Ran, X., Liu, L., & Dou, D. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/5598980 · Cited by 43
Unraveling the molecular architecture of autoimmune thyroid diseases at spatial resolution
Martínez‐Hernández, R., de la Blanca, N. S., Sacristan-Gomez, P., Serrano-Somavilla, A., de Nova, J. L. M., Sánchez‐Cabo, F., Heyn, H., Sampedro-Nuñez, M. A., & Marazuela, M. (2024) · Nature Communications · doi:10.1038/s41467-024-50192-5 · Cited by 45
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing
Vollmann, E. H., Cao, L., Amatucci, A., Reynolds, T. L., Hamann, S., Dalkilic-Liddle, I., Cameron, T. O., Hoßbach, M., Kauffman, K. J., Mir, F. F., et al. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2017.04.014 · Cited by 41
The Role of Airway Myofibroblasts in Asthma
Jendzjowsky, N. G., & Kelly, M. M. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.08.1917 · Cited by 41
The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment
Bartish, M., Abraham, M. J., Gonçalves, C., Larsson, O. S., Rolny, C., & Rincon, S. V. D. (2023) · Nature reviews. Cancer · doi:10.1038/s41568-023-00567-5 · Cited by 42
An update on myofibromas and myofibromatosis affecting the oral regions with report of 24 new cases
Smith, M. H., Reith, J. D., Cohen, D. M., Islam, N., Sibille, K. T., & Bhattacharyya, I. (2017) · Oral Surgery Oral Medicine Oral Pathology and Oral Radiology · doi:10.1016/j.oooo.2017.03.051 · Cited by 40
Metformin prevents peritendinous fibrosis by inhibiting transforming growth factor-β signaling
Zheng, W., Song, J., Zhang, Y., Chen, S., Ruan, H., & Fan, C. (2017) · Oncotarget · doi:10.18632/oncotarget.21695 · Cited by 40
Contraction of fibrin‐derived matrices and its implications for in vitro human skin bioengineering
Montero, A., Acosta, S., Hernández, R., Elvira, C., Jorcano, J. L., & Velasco, D. (2020) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37033 · Cited by 38
Knipper, K., Lyu, S. I., Quaas, A., Bruns, C. J., & Schmidt, T. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713482 · Cited by 41
Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21
Cui, X., Sun, X., Lu, F., & Jiang, X. (2018) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2018.09.007 · Cited by 38
Photobiomodulation of red and green lights in the repair process of third-degree skin burns
Simões, T. M. S., Neto, J. D. A. F., de Oliveira, T. K. B., Nonaka, C. F. W., & Catão, M. H. C. D. V. (2019) · Lasers in Medical Science · doi:10.1007/s10103-019-02776-7 · Cited by 40
Targeting persistently activated inflammatory microenvironment to promote chronic wound healing
Dai, Y., & Chen, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1708358 · Cited by 44
Saito, T., Hara, M., Kumamaru, H., Kobayakawa, K., Yokota, K., Kijima, K., Yoshizaki, S., Harimaya, K., Matsumoto, Y., Kawaguchi, K., et al. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.08.020 · Cited by 37
Midgley, A. C., Oltean, S., Hascall, V., Woods, E. L., Steadman, R., Phillips, A. O., & Meran, S. (2017) · Science Signaling · doi:10.1126/scisignal.aao1822 · Cited by 37
Mathison, M. N., Singh, V., Sanagasetti, D., Yang, L., Pinnamaneni, J. P., Yang, J., & Rosengart, T. K. (2017) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2017.06.035 · Cited by 37
Yi, M., Liu, B., Tang, Y., Li, F., Qin, W., & Yuan, X. (2018) · BioMed Research International · doi:10.1155/2018/4135806 · Cited by 36
Caffeine inhibits hypoxia-induced renal fibroblast activation by antioxidant mechanism
Nilnumkhum, A., Kanlaya, R., Yoodee, S., & Thongboonkerd, V. (2019) · Cell Adhesion & Migration · doi:10.1080/19336918.2019.1638691 · Cited by 39
Deng, B., Yang, W., Wang, D., Cheng, L., Bu, L., Rao, J., Zhang, J., Xie, J., & Zhang, B. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118465 · Cited by 36
Mesenchymal cells in the Lung: Evolving concepts and their role in fibrosis
Ligresti, G., Raslan, A., Hong, J., Caporarello, N., Confalonieri, M., & Huang, S. K. (2023) · Gene · doi:10.1016/j.gene.2022.147142 · Cited by 40
The Application of Nanoparticles Targeting Cancer-Associated Fibroblasts
Huang, Q., Ge, Y., He, Y. T., Wu, J., Tong, Y., Shang, H., Liu, X., Ba, X., Xia, D., Peng, E., et al. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s447350 · Cited by 35
Wise, L. M., Stuart, G. S., Real, N. C., Fleming, S. B., & Mercer, A. A. (2017) · Advances in Wound Care · doi:10.1089/wound.2016.0721 · Cited by 38
Fibrogenic fibroblast-selective near-infrared phototherapy to control scarring
Chen, Z., Wang, Z., Jin, T., Shen, G., Wang, Y., Tan, X., Gan, Y., Yang, F., Liu, Y., Huang, C., et al. (2019) · Theranostics · doi:10.7150/thno.36375 · Cited by 35
Yao, F., Xu, M., Dong, L., Shen, X., Shen, Y., Jiang, Y., Zhu, T., Zhang, C., & Yu, G. (2024) · BMC Pulmonary Medicine · doi:10.1186/s12890-024-03050-5 · Cited by 34
Recent developments in the pathobiology of lung myofibroblasts
Jiang, D., Dey, T., & Liu, G. (2020) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2021.1829972 · Cited by 34
Scar Formation: Cellular Mechanisms
Darby, I. A., & Desmoulière, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-44766-3_3 · Cited by 35
Self-citationLuis‐García, E. R., Becerril, C., Salgado-Aguayo, A. R., Aparicio‐Trejo, O. E., Romero, Y., Flores‐Soto, E., Mendoza-Milla, C., Montaño, M., de Sánchez, V. C., Pedraza‐Chaverrí, J., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157870 · Cited by 34
Valenzi, E., Bahudhanapati, H., Tan, J., Tabib, T., Sullivan, D. I., Nouraie, M. S., Sembrat, J., Fan, L., Chen, K., Liu, S., et al. (2023) · European Respiratory Journal · doi:10.1183/13993003.00474-2022 · Cited by 34
Deng, Z., Subilia, M., Chin, I. L., Hortin, N., Stevenson, A. W., Wood, F. M., Prêle, C. M., Choi, Y. S., & Fear, M. W. (2021) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2021.09.002 · Cited by 33
Waseem, M., Imtiaz, A., Alexander, A., Graham, L. V. D., & Contreras-Galindo, R. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102812 · Cited by 35
Metadata
- Authors
- Darby, I. A., Zakuan, N., Billet, F., & Desmoulière, A.
- Affiliations
- RMIT University (AU)
- Maintenance Myélinique et Neuropathies Périphériques (FR)
- Corresponding author
- Darby, Ian A.
- Desmoulière, Alexis
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2015-12-17
- Volume
- 73
- Issue
- 6
- Pages
- 1145-1157
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- PMC
- PMC11108523
- OpenAlex
- W2200832510
- Cited by
- 328
- References
- 143
- Citations by year
- 2026: 25 · 2025: 36 · 2024: 42 · 2023: 22 · 2022: 26 · 2021: 30 · 2020: 48 · 2019: 25 · 2018: 36 · 2017: 30 · 2016: 8
- FWCI
- 3.45
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cellular and Molecular Life Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- RMIT Research Repository (RMIT University Library) (submittedVersion)
- Figshare (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Keywords
- myofibroblasts, tissue repair, fibrosis, alpha-smooth muscle actin, extracellular matrix synthesis, skin wound healing, cancer-associated fibroblasts, stromal cells, fibroblast differentiation, apoptosis, scar formation, liver fibrosis, renal fibrosis, pulmonary fibrosis, tumor stroma
- MeSH terms
- Animals, Cicatrix, Humans, Neoplasms, Wound Healing, Myofibroblasts
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
