Modulation of Kv7 channels and excitability in the brain

Theta oscillations in the hippocampus

Buzsáki, G. (2002) · Neuron · doi:10.1016/s0896-6273(02)00586-x · Cited by 3,332

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

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KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M-Channel

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A Potassium Channel Mutation in Neonatal Human Epilepsy

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AKAP signalling complexes: focal points in space and time

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Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

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The other side of the engram: experience-driven changes in neuronal intrinsic excitability

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Synthetic resin acid derivatives selectively open the hKV7.2/7.3 channel and prevent epileptic seizures

Ottosson, N. E., Ejneby, M. S., Wu, X., Estrada‐Mondragón, A., Nilsson, M., Karlsson, U., Schupp, M., Rognant, S., Jepps, T. A., Konradsson, P., et al. (2021) · Epilepsia · doi:10.1111/epi.16932 · Cited by 6

Effects of M currents on the persistent activity of pyramidal neurons in mouse primary auditory cortex

Ye, H., Liu, Z.-X., He, Y.-J., & Wang, X. (2022) · Journal of Neurophysiology · doi:10.1152/jn.00332.2021 · Cited by 6

The potassium channels: Neurobiology and pharmacology of tinnitus

Lai, H., Gao, M., & Yang, H. (2023) · Journal of Neuroscience Research · doi:10.1002/jnr.25281 · Cited by 6

Improved classification and pathogenicity assessment by comprehensive functional studies in a large data set of KCNQ2 variants

Zhang, Y., Xue, Y., Ma, Y., Du, X., Lu, B., Wang, Y., & Yan, Z. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122378 · Cited by 6

Ethanol inhibits Kv7.2/7.3 channel open probability by reducing the PI(4,5)P2 sensitivity of Kv7.2 subunit

Kim, K.-W., & Suh, B. (2021) · BMB Reports · doi:10.5483/bmbrep.2021.54.6.231 · Cited by 6

Escalated oxycodone self-administration is associated with expression of voltage gated and calcium activated potassium channels in the mesocorticolimbic system in rats

Wabreha, A. Y., Adjei, N., Ladenheim, B., Cadet, J. L., & Daiwile, A. P. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1653356 · Cited by 5

Shared Disease Mechanisms in Neurodevelopmental Disorders: A Cellular and Molecular Biology Perspective

Pattie, E. A., & Iffland, P. H. (2025) · Brain Sciences · doi:10.3390/brainsci16010054 · Cited by 5

Attenuation of Epileptogenesis and Cognitive Deficits by a Selective and Potent Kv7 Channel Opener in Rodent Models of Seizures

Zhuang, X.-F., Liu, Y., Yang, Z.-H., Gao, Q. F., Wang, L., Ju, C., & Wang, K. (2022) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.122.001328 · Cited by 5

KCNQ2 channels regulate the population activity of neonatal GABAergic neurons ex vivo

Hou, B., Santaniello, S., & Tzingounis, A. V. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1207539 · Cited by 5

Calcium‐sensing receptor regulates Kv7 channels via Gi/o protein signalling and modulates excitability of human induced pluripotent stem cell‐derived nociceptive‐like neurons

Chuinsiri, N., Siraboriphantakul, N., Kendall, L., Yarova, P., Nile, C. J., Song, B., Obara, I., Durham, J., & Telezhkin, V. (2024) · British Journal of Pharmacology · doi:10.1111/bph.16349 · Cited by 5

Evidence for Dual Activation of IK(M) and IK(Ca) Caused by QO-58 (5-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-phenyl-2-(trifluoromethyl)-1H-pyrazolol[1,5-a]pyrimidin-7-one)

Wu, C., Fu, P., Cho, H., Chuang, T.-H., & Wu, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137042 · Cited by 5

The Epilepsy Drug Pipeline: Update on Near-to-Market Therapies

Elder, C. J., Pellinen, J., & Terman, S. W. (2025) · Seminars in Neurology · doi:10.1055/a-2580-1187 · Cited by 4

Computational simulations and Ca2+ imaging reveal that slow synaptic depolarizations (slow EPSPs) inhibit fast EPSP evoked action potentials for most of their time course in enteric neurons

Eskikand, P. Z., Koussoulas, K., Gwynne, R. M., & Bornstein, J. C. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009717 · Cited by 4

Dehydroepiandrosterone Sulfate (DHEAS) Is an Endogenous Kv7 Channel Modulator That Reduces Kv7/M-Current Suppression and Inflammatory Pain

Alhassen, L., Alhassen, W., Wong, C., Sun, Y., Xia, Z., Civelli, O., & Hoshi, N. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.2307-22.2023 · Cited by 4

Novel KCNQ1 Q234K variant, identified in patients with long QT syndrome and epileptiform activity, induces both gain- and loss-of-function of slowly activating delayed rectifier potassium currents

Nakajima, T., Tamura, S., Kawabata‐Iwakawa, R., Itoh, H., Hasegawa, H., Kobari, T., Harasawa, S., Sekine, A., Nishiyama, M., Kurabayashi, M., et al. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1401822 · Cited by 4

La douleur sous le contrôle des canaux potassiques

Busserolles, J., & Noël, J. (2016) · Douleur et Analgésie · doi:10.1007/s11724-016-0482-z · Cited by 4

High ability of zileuton ((±)-1-(1-benzo[b]thien-2-ylethyl)-1-hydroxyurea) to stimulate IK(Ca) but suppress IK(DR) and IK(M) independently of 5-lipoxygenase inhibition

Hung, T., Huang, C., & Wu, S. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173482 · Cited by 4

Heterozygous Deletion of Epilepsy Gene KCNQ2 Has Negligible Effects on Learning and Memory

Tracy, G., Wilton, A. R., Rhodes, J. S., & Chung, H. J. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.930216 · Cited by 4

Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex

Navarro-Sánchez, M., Gil‐Miravet, I., Montero-Caballero, D., Bathgate, R. A. D., Hossain, M. A., Castillo-Gómez, E., Gundlach, A. L., & Olucha-Bordonau, F. E. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116264 · Cited by 3

Proteomics of Patient-Derived Striatal Medium Spiny Neurons in Multiple System Atrophy

Smandzich, N. J., Pich, A., Gschwendtberger, T., Greten, S., Ye, L., Klietz, M., Fonzo, A. D., Henkel, L. M., & Wegner, F. (2025) · Cells · doi:10.3390/cells14171394 · Cited by 4

Casein Kinase 2 Affects Epilepsy by Regulating Ion Channels: A Potential Mechanism

Liu, Y., Xia, D., Zhong, L., Chen, L., Zhang, L., Ai, M., Mei, R., & Pang, R. (2023) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527322666230622124618 · Cited by 3

Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model

Deng, P., Kumar, A., Cavalli, V., & Klyachko, V. A. (2024) · eLife · doi:10.7554/elife.92563.3 · Cited by 3

Emerging mechanisms involving brain Kv7 channel in the pathogenesis of hypertension

Zhu, Y. F., Sheng, Z., Yao, H., & Li, D. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115318 · Cited by 6

Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, cognition, and prefrontal cortex excitabilityPreprint

Swenson, K. S., Wulschner, L. E. G., Hoelscher, V. M., Folts, L. M., Korth, K. M., Oh, W. C., & Bates, E. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.12.06.519350 · Cited by 3

Multiregional single-cell profiling reveals shared and specialized cellular vulnerability in Alzheimer’s diseasePreprint

Travaglini, K. J., Gabitto, M. I., Ding, Y., Agrawal, A., Postupna, N. O., Mahoney, J. T., Kaplan, E. S., Melief, E. J., Goldy, J., Chakka, A. B., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.01.734821 · Cited by 7

Potassium Channels in Genetic Epilepsy

Weston, M. C., & Tzingounis, A. V. (2024) · Oxford University Press eBooks · doi:10.1093/med/9780197549469.003.0045 · Cited by 3

Effects of moderate static magnetic fields on voltage‐gated potassium ion channels in sympathetic neuron‐like PC12 cells

Kaneda, E., Kawai, T., Okamura, Y., & Miyagawa, S. (2025) · Physiological Reports · doi:10.14814/phy2.70236 · Cited by 2

The Effect of Intracellular Calcium Buffer Bapta on Epileptiform Activity of Hippocampal Neurons

Зинченко, В. П., Teplov, I. Y., Tyurin, F. V., Malibayeva, A. E., Kairat, B. K., & Tuleukhanov, S. T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157596 · Cited by 2

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Wang, T., TRABZONLU, K., Jones, E. F., & Syed, Y. A. (2025) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.70009 · Cited by 2

Assessment of gabapentin efficacy in patients with KCNQ2-developmental epileptic encephalopathy

Xiong, J., You, X., Li, H., Chen, C., Duan, H., Chen, S., Cao, X., He, F. P., Fei, Y., Xiao, Z., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-55285-3 · Cited by 2

Dual regulation of Kv7.2/7.3 channels by long-chain n-alcohols

Jeong, D.-J., Kim, K.-W., & Suh, B. (2022) · The Journal of General Physiology · doi:10.1085/jgp.202213191 · Cited by 2

Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model

Deng, P., Kumar, A., Cavalli, V., & Klyachko, V. A. (2023) · eLife · doi:10.7554/elife.92563 · Cited by 6

Hormones and the Regulation of Neuronal Voltage-Sensing Ion Channels

Lyons, D. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813814-4.00011-0 · Cited by 1

Targeted M‐Channel Activation in the Left Stellate Ganglion Protects Against Ischemia‐Induced Ventricular Arrhythmias in Canines

Peng, J., Zhou, M., Xu, L., Wang, X., Tang, Y., & Liu, Y. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.039059 · Cited by 2

miR-106b-5p downregulate KCNQ2 expression contributing to incisional pain in male rats

Zhou, J., Zhao, Y., Wan, Y., Zhong, X., Liu, Q., Huang, L., Chen, X., Lin, X., & Li, H. (2025) · Journal of Pain · doi:10.1016/j.jpain.2025.105472 · Cited by 1

Activation of Kv7.2/3 channels in the PL-NAcc circuit attenuates methamphetamine-associated contextual memory

Liu, E., Hang, Z., Liu, M., Mu, S., Han, W., Fan, S., Shi, Z. S., Yue, Q., & Sun, J. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111483 · Cited by 1

Kv7 Channels as an Important Contributor to Alcohol-Induced Modulation of Neuronal Excitability in Neonatal Rat Superior Cervical Ganglion

Jeong, D.-J., Woo, J.-N., Yun, T., Bæk, M., & Suh, B. (2025) · Cells · doi:10.3390/cells14211723 · Cited by 1

Structural basis for heteromeric assembly and subthreshold activation of human M-channel

Wang, Y., Yang, H. L., Qu, Y., Li, J., Li, X., Hou, W., Wu, K., Xie, G., Wang, X., Ye, Y., et al. (2026) · Vita · doi:10.15302/vita.2026.05.0032 · Cited by 1

From venom peptides to neurotherapeutics: BmK defensins and short-chain peptides as modulators of ion channels

Dong, Y. Y., Wang, J., Zhu, Y., Zhao, L., Zeng, Y., Tang, L., Xiao, Q., Cheng, J., Wang, C., & Tao, J. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1754290 · Cited by 1

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

Zhang, Y., Zhang, X., Chen, P., Zhou, Z.-Y., Huang, M., & He, K. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71127 · Cited by 1

Temporal multi-omic exploration of the ventral tegmental area in chronic pain and passive coping behaviors

Diezel, C. C., Majuta, L. A., Bahramnejad, E., Karlage, K. L., Partin, J. L., Barbour, S. M. D., Peterson, I. L., Flowers, M., von Hippel, S. T., Haveman, R., et al. (2026) · iScience · doi:10.1016/j.isci.2026.116085 · Cited by 1

Therapeutic Effects of Kv7 Channel Activator Retigabine against Seizures and Neurodegeneration in Kainic Acid-Induced Seizure Model

Zhuang, X.-F. (2022) · International Journal of Sciences · doi:10.18483/ijsci.2598 · Cited by 1

Coronary and carotid artery dysfunction and KV7 overexpression in a mouse model of Hutchinson-Gilford progeria syndrome

Macías, Á., Nevado, R. M., González‐Gómez, C., Gonzalo, P., Andrés‐Manzano, M. J., Dorado, B., Benedicto, I., & Andrés, V. (2023) · GeroScience · doi:10.1007/s11357-023-00808-3 · Cited by 1

The Potential of Human Induced Pluripotent Stem Cells (hiPSCs) for the Study of Channelopathies: Advances and Future Directions

Disse, P., Ritter, N., Strutz‐Seebohm, N., & Seebohm, G. (2023) · Biochemistry · doi:10.5772/intechopen.112560 · Cited by 1

Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing

López-Valverde, L., Vázquez-Mosquera, M. E., Colón, C., Álvarez, J. V., López-Pardo, B. M., López, L. L., Sánchez‐Martínez, R., Mendoza, M. L., Rodriguez, M. L., Villacorta, E., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106908 · Cited by 1

A novel KCNQ2 gene mutation in a patient with self-limitted non-familial neonatal epilepsy: a case report

Nguyen, T.-H., NGUYEN, Q. M. T., LE, K. V. T., LE, M. T. T., LE, A. N. T., Phuoc, H., HUYNH, H. T. D., & DO, T. H. T. (2021) · Science & Technology Development Journal - Health Sciences · doi:10.32508/stdjhs.v2i1.445 · Cited by 1

Time-limited alterations in cortical activity of a Knock-in mice model of KCNQ2- related Developmental and Epileptic EncephalopathyPreprint

Biba, N., Becq, H., Kurz, M., Pallesi‐Pocachard, E., Villard, L., Milh, M., Lenck‐Santini, P., & Aniksztejn, L. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.12.090464 · Cited by 1

Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPreprint

Deng, P., Kumar, A., Cavalli, V., & Klyachko, V. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.27.559792 · Cited by 1

Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPreprint

Deng, P., Kumar, A., Cavalli, V., & Klyachko, V. A. (2024) · eLife · doi:10.7554/elife.92563.2 · Cited by 1

Electrical diversity of neurons in sensory corticesPreprint

Calcini, N., Zeldenrust, F., & Celikel, T. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.07.617007 · Cited by 1

Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery

Tanaka, M. (2026) · Biomedicines · doi:10.3390/biomedicines14061265

Divide, multitask, and conquer: Coordination in channel regulation

Pablo, J. L., & Pitt, G. S. (2017) · Channels · doi:10.1080/19336950.2017.1292814

KV7.2 kanala: estruktura, erregulazioa eta kitzikagarritasun neuronalean duen ekintza

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Author response: Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency

la Rossa, A. D., Laporte, M. H., Astori, S., Marissal, T., Montessuit, S., Sheshadri, P., Ramos‐Fernández, E., Méndez, P., Khani, A., Quairiaux, C., et al. (2022) · eLife · doi:10.7554/elife.72595.sa2

The mechanisms of ion chanels involved in developmental neurotoxicity due to anesthetic exposurePreprint

Zeng, S., Zhu, R., Fu, N., Li, N., & Zhang, J. (2022) · Research Square · doi:10.21203/rs.3.rs-1608420/v1

NGRI1, PIP4K2A, and HTR2K contain possible genetics

(2020) · Bioinformatics of Genome Regulation and Structure/ Systems Biology · doi:10.18699/bgrs/sb-2020-408

Lacosamide Was Effective for Epilepsy in Two Infants with KCNQ2-related Developmental and Epileptic Encephalopathy

Takeuchi, H., Matsuura, R., Kikuchi, K., Takeda, R., Hirata, Y., Koichihara, R., Oba, D., Ohashi, H., Kato, M., & Hamano, S. (2023) · てんかん研究 · doi:10.3805/jjes.41.24

Ca 2+ -sensing receptor regulates neuronal excitability via Kv7 channel and G i/o protein signallingPreprint

Chuinsiri, N., Siraboriphantakul, N., Kendall, L., Yarova, P., Nile, C. J., Song, B., Obara, I., Durham, J., & Telezhkin, V. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.07.548061

Changes in Targets as an Explanation for Drug Resistance in Epilepsy

Martínez-Aguirre, C., Fonseca‐Barriendos, D., de la Cruz, S. H., Fuentes-Mejía, M., & Rocha, L. L. (2023) · Springer eBooks · doi:10.1007/978-3-031-36526-3_7

Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPreprint

Deng, P., Kumar, A., Cavalli, V., & Klyachko, V. A. (2023) · eLife · doi:10.7554/elife.92563.1

eLife Assessment: Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model

Tóth, K. (2023) · eLife · doi:10.7554/elife.92563.1.sa3

Therapeutic Targeting of Potassium Channels

Gamper, N. L., Huang, D., Qi, J., Dong, L., & Zhang, H. (2024) · Springer eBooks · doi:10.1007/978-3-031-52197-3_5

The Role of Paraventricular Nucleus of Thalamus in Sleep Disturbance Induced by Withdrawal from Repeated Ethanol ExposurePreprint

Bennett, A., Lee, J., Kim, H., Kapoor, V., Jury, D., & Kang, S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.04.657945 · Cited by 1

Molecular Dynamics in the Ventral Tegmental Area during Chronic Pain-Induced Negative AffectPreprint

Diezel, C. C., Majuta, L. A., Bahramnejad, E., Karlage, K. L., Partin, J. L., Barbour, S. M. D., Peterson, I. L., Flowers, M., von Hippel, S. T., Haveman, R., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.01.662604

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Song, H., Wang, Y., Wang, L., Guo, C., Liu, S., Rong, Y., Tian, J., Peng, C., Shao, Y., Ma, Z., et al. (2025) · Advanced Science · doi:10.1002/advs.202416315

Elucidation of the zinc binding site in KCNQ channels

Zhang, S., Yang, X., Yang, M., Cao, Y., Shi, S., Gamper, N. L., & Gao, H. (2025) · British Journal of Pharmacology · doi:10.1111/bph.70177

α2A-AR–Kv dysfunction drives LC hyperactivity and early sleep disturbance in amyloidogenic micePreprint

Zhang, Y.-C., Zhang, X., Chen, P., Zhou, Z.-Y., Huang, M.-Q., & He, K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.26.678734

Additional file 1 of An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

Urrutia, J., Aguado, A., Gomis-Perez, C., Muguruza‐Montero, A., Ballesteros, Ó. R., Zhang, J., Nuñez, E., Malo, C., Chung, H. J., Leonardo, A., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14643274

La contribution du courant potassique M dans les processus physio-pathologiques de la locomotion

Verneuil, J. (2021) · theses.fr (ABES) · doi:10.70675/d6aff829z706az473az9150zbe286f56aa0a

Caractérisation et intérêt thérapeutique de potentialisateurs du co-transporteur potassium-chlorure de type 2 (KCC2) dans les épilepsies du lobe temporal

Donneger, F. (2022) · theses.fr (ABES) · doi:10.70675/753a050cz1c18z423ez94f8zc1e748a6fa26

Etude des mécanismes physiopathologiques des encéphalopathies épileptiques et développementales précoces liés au variant p.T274M de KCNQ2

Biba, N. (2022) · theses.fr (ABES) · doi:10.70675/43c27dcaz3845z4a00z9f34zf2ee057a5e9b

Modulation des interneurones oriens - lacunosum moleculare

Sammari, M. (2023) · theses.fr (ABES) · doi:10.70675/edb26e6fz1bf5z491eza5e4z3f69bc9761e1

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

Kim, Y. W., Behara, P. K., Alhassen, L., Wong, C., Civelli, O., & Hoshi, N. (2026) · British Journal of Pharmacology · doi:10.1111/bph.70432

K v 7 and K 2P Potassium Channels in Thalamocortical Function and Their Therapeutic Potential in Childhood Absence Epilepsy

Takhi, A., Seebohm, G., Budde, T., & Lüttjohann, A. (2026) · Archiv der Pharmazie · doi:10.1002/ardp.70276 · Cited by 1

Kv7 channels as pharmacological targets for central nervous system diseases

Miceli, F., Soldovieri, M. V., Barrese, V., & Taglialatela, M. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100153 · Cited by 1

KV7 channel activation inhibits human and murine myometrium contractility and delays delivery in a mouse model of preterm birth

Mansour, Y. T., Mistry, H. D., Chin-Smith, E. C., Zaleska, M., Sekulich, D. C., Herington, J. L., Reese, J., Patel, R., Aaronson, P. I., Slater, D. M., et al. (2026) · Communications Medicine · doi:10.1038/s43856-026-01861-7

Preclinical investigation of the therapeutic effects of hydromethanolic leaf extract of Manihot esculenta on hyperglycemia-induced hepatorenal dysfunction: An integrated In Vitro, In Vivo, and In Silico study

Salawu, M. O., Moronfolu, I. A., & Yusuf, B. O. (2026) · Pharmacological Research - Natural Products · doi:10.1016/j.prenap.2026.100905

BindingDB Entry 50017387: Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate.

BindingDB (2023) · UC San Diego · doi:10.7270/q28g8qsz

BindingDB Entry 50016353: General Pharmacological Activation Mechanism of K

BindingDB (2023) · UC San Diego · doi:10.7270/q2gq72rj

Kv7 channels as pharmacological targets for central nervous system diseases

Miceli, F., Soldovieri, M. V., Barrese, V., & Taglialatela, M. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100153 · Cited by 1

Mutations in Kv7.5 Channels Associated with Intellectual Disability or Epileptic Encephalopathy

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