The DOI matches its Crossref record; 234 of the 234 references it cites were found in a registry or an index.
Bridging intestinal immunity and gut microbiota by metabolites
Open accessAbstract
The gastrointestinal tract is the site of nutrient digestion and absorption and is also colonized by diverse, highly mutualistic microbes. The intestinal microbiota has diverse effects on the development and function of the gut-specific immune system, and provides some protection from infectious pathogens. However, interactions between intestinal immunity and microorganisms are very complex, and recent studies have revealed that this intimate crosstalk may depend on the production and sensing abilities of multiple bioactive small molecule metabolites originating from direct produced by the gut microbiota or by the metabolism of dietary components. Here, we review the interplay between the host immune system and the microbiota, how commensal bacteria regulate the production of metabolites, and how these microbiota-derived products influence the function of several major innate and adaptive immune cells involved in modulating host immune homeostasis.
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Cites
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Self-citationHost-gut microbiota metabolic interactions
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Cited by
Wang, G., Fan, Y., Zhang, G., Cai, S., Ma, Y., Yang, L., Wang, Y., Yu, H., Qiao, S., & Zeng, X. (2024) · Microbiome · doi:10.1186/s40168-024-01750-y · Cited by 299
Self-citationMicrobiota-Derived Short-Chain Fatty Acids Promote LAMTOR2-Mediated Immune Responses in Macrophages
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Beneficial effect of vinegar consumption associated with regulating gut microbiome and metabolome
Xia, T., Kang, C., Qiang, X., Zhang, X., Li, S., Liang, K., Wang, Y., Wang, J., Cao, H., & Wang, M. (2024) · Current Research in Food Science · doi:10.1016/j.crfs.2023.100566 · Cited by 26
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Metadata
- Authors
- Wang, G., Huang, S., Wang, Y., Cai, S., Yu, H., Liu, H., Zeng, X., Zhang, G., & Qiao, S.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2019-06-27
- Volume
- 76
- Issue
- 20
- Pages
- 3917-3937
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- OpenAlex
- W2954197440
- Cited by
- 293
- References
- 234
- FWCI
- 9.67
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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